full name
S-phase kinase associated protein 1

synonyms
EMC19, OCP-II, OCP2, p19A, SKP1A, TCEB1L, SKP1, ENSG00000113558

HGNC
HGNC:10899

Entrez Gene
Gene:6500

ENSEMBL
ENSG00000113558

location
chr: 5
start: 133492082
stop: 133512724
strand: -

transcripts
NM_170679.2
NM_006930.3

pathways
APC/C-mediated degradation of cell cycle proteins [NCBI:1269838] [REACTOME:R-HSA-174143] [PUBMED:15678131] [PUBMED:12049731]
Activated TLR4 signalling [NCBI:1269236] [REACTOME:R-HSA-166054] [PUBMED:15276183] [PUBMED:15588429] [PUBMED:15845500] [PUBMED:15596121]
Activation of NF-kappaB in B cells [NCBI:1269186] [REACTOME:R-HSA-1169091] [PUBMED:10593898] [PUBMED:3129195] [PUBMED:7479848] [PUBMED:7809113] [PUBMED:9721103] [PUBMED:18462924] [PUBMED:8387275] [PUBMED:7628694] [PUBMED:7862124] [PUBMED:7831327] [PUBMED:7575604] [PUBMED:16356855] [PUBMED:16301747] [PUBMED:7957109] [PUBMED:11460167] [PUBMED:9914500] [PUBMED:19066035] [PUBMED:17428801] [PUBMED:7479976] [PUBMED:1756723]
Adaptive Immune System [NCBI:1269171] [REACTOME:R-HSA-1280218] [PUBMED:16551257] [PUBMED:21682741] [PUBMED:11861602]
Antigen processing: Ubiquitination & Proteasome degradation [NCBI:1269193] [REACTOME:R-HSA-983168] [PUBMED:12648452] [PUBMED:11917093] [PUBMED:19489725] [PUBMED:14734113] [PUBMED:20351195] [PUBMED:17145306]
C-type lectin receptors (CLRs) [NCBI:1269303] [REACTOME:R-HSA-5621481] [PUBMED:19521399] [PUBMED:24330199]
CLEC7A (Dectin-1) signaling [NCBI:1269304] [REACTOME:R-HSA-5607764] [PUBMED:12719478] [PUBMED:19223162]
Canonical Wnt signaling pathway [NCBI:138032] [Pathway Interaction Database:wnt_canonical_pathway] [PUBMED:16849322] [PUBMED:10228155] [PUBMED:11007767] [PUBMED:10023673] [PUBMED:19061640] [PUBMED:10074433] [PUBMED:9554852] [PUBMED:10196136] [PUBMED:18772438] [PUBMED:19309792] [PUBMED:16263762] [PUBMED:16890161] [PUBMED:16341017] [PUBMED:17569865] [PUBMED:16314428] [PUBMED:17529994] [PUBMED:10421629] [PUBMED:11751573] [PUBMED:20177058] [PUBMED:15024404] [PUBMED:12000790] [PUBMED:19107203] [PUBMED:10684251] [PUBMED:9482734] [PUBMED:16547521] [PUBMED:10092233] [PUBMED:18077588] [PUBMED:16303557] [PUBMED:19556239] [PUBMED:19561074] [PUBMED:11274398] [PUBMED:14966280] [PUBMED:9566905] [PUBMED:11834740] [PUBMED:19801552] [PUBMED:12554650] [PUBMED:16341016] [PUBMED:17510365] [PUBMED:15459103] [PUBMED:18929646] [PUBMED:15327768] [PUBMED:9312064]
Cell Cycle [NCBI:1269741] [REACTOME:R-HSA-1640170]
Cell Cycle, Mitotic [NCBI:1269763] [REACTOME:R-HSA-69278]
Cell cycle [NCBI:83054] [KEGG:hsa04110] [PUBMED:7973727] [PUBMED:17568790] [PUBMED:9832503] [PUBMED:16936746] [PUBMED:9029154] [PUBMED:12573239] [PUBMED:19020303] [PUBMED:9618481] [PUBMED:12809600] [PUBMED:8242749] [PUBMED:10385618] [PUBMED:17426725] [PUBMED:17018296] [PUBMED:16212951] [PUBMED:12925736] [PUBMED:11099028] [PUBMED:15568976] [PUBMED:15838516] [PUBMED:15838523] [PUBMED:15876871] [PUBMED:7908906] [PUBMED:9889196]
Circadian Clock [NCBI:1269871] [REACTOME:R-HSA-400253] [PUBMED:18775307] [PUBMED:18802415] [PUBMED:18786386] [PUBMED:16987893]
Circadian rhythm [NCBI:83084] [KEGG:hsa04710] [PUBMED:17586087] [PUBMED:12507418] [PUBMED:10864977] [PUBMED:18802415] [PUBMED:17463251] [PUBMED:12150932] [PUBMED:11687489] [PUBMED:12724733] [PUBMED:12015613] [PUBMED:11533719] [PUBMED:12397359] [PUBMED:15917222] [PUBMED:11165242]
Class I MHC mediated antigen processing & presentation [NCBI:1269192] [REACTOME:R-HSA-983169] [PUBMED:8717519] [PUBMED:17145306] [PUBMED:18926908] [PUBMED:17055423] [PUBMED:12495737] [PUBMED:18641646] [PUBMED:18243674]
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants [NCBI:1268891] [REACTOME:R-HSA-2894862] [PUBMED:15472075] [PUBMED:17646408] [PUBMED:17646409] [PUBMED:16738328]
Constitutive Signaling by NOTCH1 PEST Domain Mutants [NCBI:1268889] [REACTOME:R-HSA-2644606] [PUBMED:15472075] [PUBMED:17646408] [PUBMED:17646409]
Cyclin A:Cdk2-associated events at S phase entry [NCBI:1269778] [REACTOME:R-HSA-69656] [PUBMED:7629134] [PUBMED:11231585] [PUBMED:1396589] [PUBMED:15014502] [PUBMED:10454565] [PUBMED:11907280]
Cyclin D associated events in G1 [NCBI:1269767] [REACTOME:R-HSA-69231]
Cyclin E associated events during G1/S transition [NCBI:1269769] [REACTOME:R-HSA-69202]
Cytokine Signaling in Immune system [NCBI:1269310] [REACTOME:R-HSA-1280215] [PUBMED:12613569]
Dectin-1 mediated noncanonical NF-kB signaling [NCBI:1269306] [REACTOME:R-HSA-5607761] [PUBMED:19521399] [PUBMED:19302050] [PUBMED:23570314]
Degradation of GLI1 by the proteasome [NCBI:1269639] [REACTOME:R-HSA-5610780] [PUBMED:17283082] [PUBMED:10075717] [PUBMED:10725236] [PUBMED:21921029] [PUBMED:12361967]
Degradation of GLI2 by the proteasome [NCBI:1269638] [REACTOME:R-HSA-5610783] [PUBMED:19056373] [PUBMED:17283082] [PUBMED:23719536] [PUBMED:16611981]
Degradation of beta-catenin by the destruction complex [NCBI:1269596] [REACTOME:R-HSA-195253] [PUBMED:17143292]
Disease [NCBI:1268854] [REACTOME:R-HSA-1643685]
Diseases of signal transduction [NCBI:1268855] [REACTOME:R-HSA-5663202] [PUBMED:12509752]
Downstream TCR signaling [NCBI:1269176] [REACTOME:R-HSA-202424] [PUBMED:15084594]
Downstream signaling events of B Cell Receptor (BCR) [NCBI:1269185] [REACTOME:R-HSA-1168372] [PUBMED:17052215] [PUBMED:19909372]
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis [NCBI:1457807] [REACTOME:R-HSA-8854050] [PUBMED:25654763] [PUBMED:22306998]
FBXW7 Mutants and NOTCH1 in Cancer [NCBI:1268892] [REACTOME:R-HSA-2644605] [PUBMED:17909001] [PUBMED:17646409] [PUBMED:15546612] [PUBMED:11461910] [PUBMED:11585921] [PUBMED:17646408]
FCERI mediated NF-kB activation [NCBI:1269301] [REACTOME:R-HSA-2871837] [PUBMED:17336609] [PUBMED:16432253]
Fc epsilon receptor (FCERI) signaling [NCBI:1269298] [REACTOME:R-HSA-2454202] [PUBMED:15099567] [PUBMED:21799019]
G1 Phase [NCBI:1269766] [REACTOME:R-HSA-69236]
G1/S Transition [NCBI:1269768] [REACTOME:R-HSA-69206]
G2/M Transition [NCBI:1269799] [REACTOME:R-HSA-69275]
GLI3 is processed to GLI3R by the proteasome [NCBI:1269637] [REACTOME:R-HSA-5610785] [PUBMED:21921029] [PUBMED:20154143] [PUBMED:16371461] [PUBMED:10693759] [PUBMED:16705181] [PUBMED:17283082]
HIV Infection [NCBI:1269057] [REACTOME:R-HSA-162906] [PUBMED:16354571] [PUBMED:9759480]
Hedgehog 'off' state [NCBI:1269636] [REACTOME:R-HSA-5610787] [PUBMED:21801010] [PUBMED:20395968] [PUBMED:23719536] [PUBMED:21502959]
Herpes simplex infection [NCBI:377873] [KEGG:hsa05168] [PUBMED:12224518] [PUBMED:17913820] [PUBMED:12844494] [PUBMED:10998601] [PUBMED:15163721] [PUBMED:19694546] [PUBMED:16297150] [PUBMED:14747533] [PUBMED:12826401] [PUBMED:14963113] [PUBMED:15056211] [PUBMED:12797447] [PUBMED:21107701] [PUBMED:10918307] [PUBMED:10696424] [PUBMED:16076403] [PUBMED:10364308] [PUBMED:17222692] [PUBMED:9621021] [PUBMED:12224508] [PUBMED:19879619] [PUBMED:11070032] [PUBMED:9499021] [PUBMED:18596690] [PUBMED:12525427] [PUBMED:12224517] [PUBMED:10196275] [PUBMED:15047834] [PUBMED:18508584] [PUBMED:20036979]
Host Interactions of HIV factors [NCBI:1269091] [REACTOME:R-HSA-162909]
Immune System [NCBI:1269170] [REACTOME:R-HSA-168256]
Infectious disease [NCBI:1269056] [REACTOME:R-HSA-5663205]
Innate Immune System [NCBI:1269203] [REACTOME:R-HSA-168249]
Interleukin-1 signaling [NCBI:1269320] [REACTOME:R-HSA-446652] [PUBMED:19302047] [PUBMED:19022706]
Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling [NCBI:1268893] [REACTOME:R-HSA-2644607] [PUBMED:15546612] [PUBMED:17646408] [PUBMED:17646409] [PUBMED:12553912]
MAP kinase activation in TLR cascade [NCBI:1269211] [REACTOME:R-HSA-450294] [PUBMED:17637696] [PUBMED:11861597] [PUBMED:19196711] [PUBMED:11242034]
MAP3K8 (TPL2)-dependent MAPK1/3 activation [NCBI:1309122] [REACTOME:R-HSA-5684264] [PUBMED:22733995] [PUBMED:21135874]
Mitotic G1-G1/S phases [NCBI:1269764] [REACTOME:R-HSA-453279]
Mitotic G2-G2/M phases [NCBI:1269797] [REACTOME:R-HSA-453274]
MyD88 cascade initiated on plasma membrane [NCBI:1269207] [REACTOME:R-HSA-975871] [PUBMED:15728506] [PUBMED:16239509]
MyD88 dependent cascade initiated on endosome [NCBI:1269228] [REACTOME:R-HSA-975155] [PUBMED:20237413] [PUBMED:15276183] [PUBMED:18652679]
MyD88-independent TLR3/TLR4 cascade [NCBI:1269220] [REACTOME:R-HSA-166166] [PUBMED:15276183]
MyD88:Mal cascade initiated on plasma membrane [NCBI:1269237] [REACTOME:R-HSA-166058] [PUBMED:15276183]
NIK-->noncanonical NF-kB signaling [NCBI:1269331] [REACTOME:R-HSA-5676590] [PUBMED:22017430] [PUBMED:18322009] [PUBMED:19302050] [PUBMED:21173796]
NOTCH1 Intracellular Domain Regulates Transcription [NCBI:1269537] [REACTOME:R-HSA-2122947] [PUBMED:11044625] [PUBMED:8649374] [PUBMED:21737748] [PUBMED:9694793] [PUBMED:20972443] [PUBMED:11585921] [PUBMED:17114293] [PUBMED:8001118] [PUBMED:18094723] [PUBMED:8687460] [PUBMED:16256737] [PUBMED:16530044] [PUBMED:12050117] [PUBMED:10964718] [PUBMED:12391150] [PUBMED:7566092] [PUBMED:15546612] [PUBMED:15107403] [PUBMED:18374649] [PUBMED:14980219] [PUBMED:11461910] [PUBMED:10713164]
Notch signaling pathway [NCBI:83062] [KEGG:hsa04330] [NCBI:169345] [Pathway Interaction Database:notch_pathway] [PUBMED:11459941] [PUBMED:12682059] [PUBMED:11825871] [PUBMED:17658278] [PUBMED:15998794] [PUBMED:11101851] [PUBMED:19686683] [PUBMED:18490439] [PUBMED:11150244] [PUBMED:9694793] [PUBMED:10206645] [PUBMED:19704010] [PUBMED:16137758] [PUBMED:15288258] [PUBMED:17392792] [PUBMED:8749394] [PUBMED:15965470] [PUBMED:14566063] [PUBMED:19567869] [PUBMED:11585921] [PUBMED:18676613] [PUBMED:12913000] [PUBMED:10593990] [PUBMED:15274632] [PUBMED:11777909] [PUBMED:12015972] [PUBMED:10028969] [PUBMED:18043734] [PUBMED:17658279] [PUBMED:17575125] [PUBMED:10958687] [PUBMED:15300010] [PUBMED:10882062] [PUBMED:12374742] [PUBMED:11782429] [PUBMED:9653148] [PUBMED:9315665] [PUBMED:8643690] [PUBMED:17114293] [PUBMED:10837024] [PUBMED:15067010] [PUBMED:17296795] [PUBMED:10940313] [PUBMED:18628966] [PUBMED:12826675] [PUBMED:12681948] [PUBMED:16492672] [PUBMED:12551931] [PUBMED:15082708] [PUBMED:12464310] [PUBMED:12794186] [PUBMED:16107360] [PUBMED:19726682] [PUBMED:11486031] [PUBMED:16287852] [PUBMED:12297508] [PUBMED:16061358] [PUBMED:17107962] [PUBMED:9244302] [PUBMED:11425854] [PUBMED:9620803] [PUBMED:15272268] [PUBMED:18417156] [PUBMED:16000382] [PUBMED:11896183] [PUBMED:11604511] [PUBMED:16847353] [PUBMED:11432830] [PUBMED:15652348] [PUBMED:12417415] [PUBMED:14567914] [PUBMED:11006133] [PUBMED:18077452] [PUBMED:16144902] [PUBMED:15288257] [PUBMED:15585829] [PUBMED:12370315] [PUBMED:15288260] [PUBMED:17434929] [PUBMED:12814948] [PUBMED:10882063] [PUBMED:11518718]
Oocyte meiosis [NCBI:126909] [KEGG:hsa04114] [PUBMED:16760654] [PUBMED:17480229] [PUBMED:15136768] [PUBMED:18946022] [PUBMED:18598214] [PUBMED:16518630] [PUBMED:18631137] [PUBMED:15182704] [PUBMED:15182701] [PUBMED:16554437] [PUBMED:14691134] [PUBMED:18550795] [PUBMED:18096427] [PUBMED:14517314] [PUBMED:18311174]
Prolactin receptor signaling [NCBI:1269328] [REACTOME:R-HSA-1170546] [PUBMED:9626554] [PUBMED:11356125] [PUBMED:11826263]
Protein processing in endoplasmic reticulum [NCBI:167325] [KEGG:hsa04141] [PUBMED:20347046] [PUBMED:18023214] [PUBMED:20219571] [PUBMED:19491040] [PUBMED:20112977]
Regulation of APC/C activators between G1/S and early anaphase [NCBI:1269839] [REACTOME:R-HSA-176408] [PUBMED:16508672] [PUBMED:12049731] [PUBMED:12208841] [PUBMED:15678131]
Regulation of PLK1 Activity at G2/M Transition [NCBI:1269803] [REACTOME:R-HSA-2565942] [PUBMED:12207013] [PUBMED:18615013] [PUBMED:13678582] [PUBMED:18378770] [PUBMED:18566290] [PUBMED:18477460] [PUBMED:22365832]
Regulation of Wnt-mediated beta catenin signaling and target gene transcription [NCBI:169352] [Pathway Interaction Database:wnt_beta_catenin_pathway] [PUBMED:19901072] [PUBMED:19699733] [PUBMED:15142975] [PUBMED:16565090] [PUBMED:17372190] [PUBMED:17310985] [PUBMED:11751639] [PUBMED:16301527] [PUBMED:10921920] [PUBMED:8622675] [PUBMED:19571879] [PUBMED:11445543] [PUBMED:19066453] [PUBMED:15768032] [PUBMED:10704849] [PUBMED:19940019] [PUBMED:15378020] [PUBMED:10318916] [PUBMED:10617567] [PUBMED:19435523] [PUBMED:18511409] [PUBMED:18006687] [PUBMED:14638683] [PUBMED:15782138] [PUBMED:15143193] [PUBMED:9671490] [PUBMED:11263497] [PUBMED:18193033] [PUBMED:9751710] [PUBMED:11532957] [PUBMED:10898789] [PUBMED:11266540] [PUBMED:17090534] [PUBMED:15492215] [PUBMED:16309666] [PUBMED:12502739] [PUBMED:10980707] [PUBMED:17945188] [PUBMED:11572874] [PUBMED:11809808] [PUBMED:17113388] [PUBMED:20128690] [PUBMED:17709391] [PUBMED:11500377] [PUBMED:12464179] [PUBMED:18347071] [PUBMED:18347094] [PUBMED:15592430] [PUBMED:10958684] [PUBMED:12408825] [PUBMED:15525529] [PUBMED:16581771] [PUBMED:12052822] [PUBMED:15668231] [PUBMED:16014379] [PUBMED:17923689] [PUBMED:15592505] [PUBMED:10984057] [PUBMED:20044351] [PUBMED:11940574] [PUBMED:10747853] [PUBMED:12606575] [PUBMED:15728254] [PUBMED:11080158] [PUBMED:12446687] [PUBMED:20128911] [PUBMED:19816403] [PUBMED:18573912] [PUBMED:17397822] [PUBMED:10489374] [PUBMED:17052462] [PUBMED:20371816] [PUBMED:18347063] [PUBMED:11035805] [PUBMED:11792709] [PUBMED:16899215] [PUBMED:10882123] [PUBMED:12200448] [PUBMED:15060161] [PUBMED:12711682] [PUBMED:12582159] [PUBMED:12646922] [PUBMED:19460168] [PUBMED:16778892] [PUBMED:17306568] [PUBMED:12712206] [PUBMED:19711354] [PUBMED:17893322] [PUBMED:10934025] [PUBMED:19503085] [PUBMED:19433865]
Regulation of mitotic cell cycle [NCBI:1269837] [REACTOME:R-HSA-453276]
S Phase [NCBI:1269777] [REACTOME:R-HSA-69242]
SCF(Skp2)-mediated degradation of p27/p21 [NCBI:1269770] [REACTOME:R-HSA-187577] [PUBMED:7624798] [PUBMED:14532004] [PUBMED:12730199]
SCF-beta-TrCP mediated degradation of Emi1 [NCBI:1269841] [REACTOME:R-HSA-174113] [PUBMED:12791267]
Signal Transduction [NCBI:1269379] [REACTOME:R-HSA-162582] [PUBMED:17604717] [PUBMED:19648010] [PUBMED:16260143] [PUBMED:11742412] [PUBMED:19536106] [PUBMED:15863030] [PUBMED:19379690] [PUBMED:19458711] [PUBMED:19935667] [PUBMED:21252999] [PUBMED:15520807] [PUBMED:17496910] [PUBMED:15450248] [PUBMED:18043707] [PUBMED:16939974] [PUBMED:19762341] [PUBMED:18483217] [PUBMED:17084981] [PUBMED:21781017] [PUBMED:19619488]
Signaling by Hedgehog [NCBI:1269633] [REACTOME:R-HSA-5358351] [PUBMED:19081070] [PUBMED:21801010] [PUBMED:15549094] [PUBMED:23719536]
Signaling by Interleukins [NCBI:1269318] [REACTOME:R-HSA-449147] [PUBMED:19302047] [PUBMED:12445398]
Signaling by NOTCH [NCBI:1269530] [REACTOME:R-HSA-157118]
Signaling by NOTCH1 [NCBI:1269535] [REACTOME:R-HSA-1980143] [PUBMED:20972443] [PUBMED:8649374] [PUBMED:11740940] [PUBMED:15965470] [PUBMED:16284625] [PUBMED:9694793] [PUBMED:19567869] [PUBMED:12354787] [PUBMED:11585921] [PUBMED:20418862] [PUBMED:11226752] [PUBMED:9590294] [PUBMED:9315665] [PUBMED:17114293] [PUBMED:18094723] [PUBMED:10964718] [PUBMED:10879540] [PUBMED:8001118] [PUBMED:12050117] [PUBMED:18043734] [PUBMED:9819428] [PUBMED:15824097] [PUBMED:9244301] [PUBMED:16256737] [PUBMED:8687460] [PUBMED:19726682] [PUBMED:8313469] [PUBMED:15574878] [PUBMED:18296446] [PUBMED:16530044] [PUBMED:9620803] [PUBMED:18237417] [PUBMED:7566092] [PUBMED:18628966] [PUBMED:12391150] [PUBMED:12530964] [PUBMED:11006133] [PUBMED:18374649] [PUBMED:15107403] [PUBMED:18077452] [PUBMED:15652348] [PUBMED:15546612] [PUBMED:10882063] [PUBMED:14980219] [PUBMED:10713164] [PUBMED:9462510] [PUBMED:11461910] [PUBMED:14567914] [PUBMED:17003037] [PUBMED:17028573] [PUBMED:11044625] [PUBMED:10206645] [PUBMED:19524514]
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer [NCBI:1268890] [REACTOME:R-HSA-2894858] [PUBMED:15472075]
Signaling by NOTCH1 PEST Domain Mutants in Cancer [NCBI:1268888] [REACTOME:R-HSA-2644602] [PUBMED:17646408] [PUBMED:15472075] [PUBMED:17646409]
Signaling by NOTCH1 in Cancer [NCBI:1268883] [REACTOME:R-HSA-2644603] [PUBMED:17646409] [PUBMED:10367900] [PUBMED:16738328] [PUBMED:15951812] [PUBMED:22399357] [PUBMED:15546612] [PUBMED:11461910] [PUBMED:9118226] [PUBMED:15951813] [PUBMED:17646408] [PUBMED:15472075] [PUBMED:11585921] [PUBMED:17909001] [PUBMED:16612405] [PUBMED:1831692] [PUBMED:15187027]
Signaling by Wnt [NCBI:1269594] [REACTOME:R-HSA-195721] [PUBMED:19530173] [PUBMED:23256519] [PUBMED:22952392] [PUBMED:19204114] [PUBMED:19365405] [PUBMED:19619488] [PUBMED:17143292] [PUBMED:17230199] [PUBMED:18710302] [PUBMED:16099039] [PUBMED:20576942] [PUBMED:10858654] [PUBMED:12967557]
Signaling by the B Cell Receptor (BCR) [NCBI:1269183] [REACTOME:R-HSA-983705] [PUBMED:1702903] [PUBMED:2011584] [PUBMED:1081164] [PUBMED:19065780] [PUBMED:16849466] [PUBMED:1375264] [PUBMED:7538118] [PUBMED:11901194] [PUBMED:8580068] [PUBMED:19249086] [PUBMED:18596693] [PUBMED:10648173] [PUBMED:4589993] [PUBMED:8163536] [PUBMED:1376928] [PUBMED:7688784] [PUBMED:6335036] [PUBMED:17052215] [PUBMED:18818202] [PUBMED:20206686] [PUBMED:7592958] [PUBMED:7524079] [PUBMED:15489917] [PUBMED:15509800] [PUBMED:18187424] [PUBMED:7927516] [PUBMED:803528] [PUBMED:19909372] [PUBMED:20192804] [PUBMED:8306975]
TCR signaling [NCBI:1269172] [REACTOME:R-HSA-202403] [PUBMED:10375551] [PUBMED:12876557] [PUBMED:9989491]
TGF-beta signaling pathway [NCBI:83064] [KEGG:hsa04350] [PUBMED:11836504] [PUBMED:14534577] [PUBMED:10021351] [PUBMED:12809600] [PUBMED:14557817] [PUBMED:14769828] [PUBMED:10519551] [PUBMED:12163231] [PUBMED:19758997] [PUBMED:12466190] [PUBMED:11252746] [PUBMED:15063168] [PUBMED:9847239] [PUBMED:11252892]
TNFR2 non-canonical NF-kB pathway [NCBI:1269329] [REACTOME:R-HSA-5668541] [PUBMED:19680262] [PUBMED:24298274] [PUBMED:21173796] [PUBMED:20489699] [PUBMED:24432023] [PUBMED:21232019] [PUBMED:22017430]
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation [NCBI:1269229] [REACTOME:R-HSA-975138] [PUBMED:22511786] [PUBMED:18794297]
TRIF-mediated TLR3/TLR4 signaling [NCBI:1269221] [REACTOME:R-HSA-937061] [PUBMED:15814722] [PUBMED:12855817] [PUBMED:14739303]
Toll Like Receptor 10 (TLR10) Cascade [NCBI:1269206] [REACTOME:R-HSA-168142] [PUBMED:15728506] [PUBMED:18332149]
Toll Like Receptor 2 (TLR2) Cascade [NCBI:1269238] [REACTOME:R-HSA-181438] [PUBMED:10820283]
Toll Like Receptor 3 (TLR3) Cascade [NCBI:1269219] [REACTOME:R-HSA-168164] [PUBMED:19627256] [PUBMED:15733829] [PUBMED:18202435]
Toll Like Receptor 4 (TLR4) Cascade [NCBI:1269234] [REACTOME:R-HSA-166016]
Toll Like Receptor 5 (TLR5) Cascade [NCBI:1269226] [REACTOME:R-HSA-168176] [PUBMED:11489966] [PUBMED:11323673]
Toll Like Receptor 7/8 (TLR7/8) Cascade [NCBI:1269227] [REACTOME:R-HSA-168181] [PUBMED:14976262]
Toll Like Receptor 9 (TLR9) Cascade [NCBI:1269233] [REACTOME:R-HSA-168138] [PUBMED:14751759]
Toll Like Receptor TLR1:TLR2 Cascade [NCBI:1269239] [REACTOME:R-HSA-168179] [PUBMED:12975352]
Toll Like Receptor TLR6:TLR2 Cascade [NCBI:1269240] [REACTOME:R-HSA-168188] [PUBMED:14977973]
Toll-Like Receptors Cascades [NCBI:1269204] [REACTOME:R-HSA-168898] [PUBMED:15950447] [PUBMED:12893815] [PUBMED:15976490] [PUBMED:15585605] [PUBMED:14751757]
Ubiquitin mediated proteolysis [NCBI:83056] [KEGG:hsa04120] [PUBMED:16405856] [PUBMED:12944364] [PUBMED:16922408] [PUBMED:17588513] [PUBMED:16922367] [PUBMED:16922370] [PUBMED:16816840]
Vpu mediated degradation of CD4 [NCBI:1269107] [REACTOME:R-HSA-180534] [PUBMED:16354571] [PUBMED:15578980]
Wnt signaling pathway [NCBI:83061] [KEGG:hsa04310] [PUBMED:12446114] [PUBMED:14745971] [PUBMED:14530294] [PUBMED:15102436] [PUBMED:14635791] [PUBMED:19482104] [PUBMED:23256519] [PUBMED:12967557] [PUBMED:11433294] [PUBMED:18838381]