full name
ubiquitin conjugating enzyme E2 B

synonyms
E2-17kDa, HHR6B, HR6B, RAD6B, UBC2, UBE2B, ENSG00000119048

HGNC
HGNC:12473

Entrez Gene
Gene:7320

ENSEMBL
ENSG00000119048

location
chr: 5
start: 133706843
stop: 133727799
strand: +

OMIM
OMIM:179095: UBE2B

transcripts
NM_003337.2

pathways
Adaptive Immune System [NCBI:1269171] [REACTOME:R-HSA-1280218] [PUBMED:16551257] [PUBMED:21682741] [PUBMED:11861602]
Antigen processing: Ubiquitination & Proteasome degradation [NCBI:1269193] [REACTOME:R-HSA-983168] [PUBMED:12648452] [PUBMED:11917093] [PUBMED:19489725] [PUBMED:14734113] [PUBMED:20351195] [PUBMED:17145306]
Class I MHC mediated antigen processing & presentation [NCBI:1269192] [REACTOME:R-HSA-983169] [PUBMED:8717519] [PUBMED:17145306] [PUBMED:18926908] [PUBMED:17055423] [PUBMED:12495737] [PUBMED:18641646] [PUBMED:18243674]
DNA Damage Bypass [NCBI:1270367] [REACTOME:R-HSA-73893] [PUBMED:21605556] [PUBMED:10925197] [PUBMED:11595180] [PUBMED:12800216] [PUBMED:19225445] [PUBMED:25038291]
DNA Repair [NCBI:1270350] [REACTOME:R-HSA-73894] [PUBMED:10583946] [PUBMED:23175119]
E3 ubiquitin ligases ubiquitinate target proteins [NCBI:1470927] [REACTOME:R-HSA-8866654] [PUBMED:23747565] [PUBMED:27312108] [PUBMED:24699078] [PUBMED:19489725] [PUBMED:23912815] [PUBMED:22389392] [PUBMED:17588513] [PUBMED:19436320] [PUBMED:23732108] [PUBMED:19754430] [PUBMED:23624913] [PUBMED:23657496] [PUBMED:26085183]
Immune System [NCBI:1269170] [REACTOME:R-HSA-168256]
Metabolism of proteins [NCBI:1268677] [REACTOME:R-HSA-392499]
Post-translational protein modification [NCBI:1268701] [REACTOME:R-HSA-597592]
Protein ubiquitination [NCBI:1457808] [REACTOME:R-HSA-8852135] [PUBMED:23912815] [PUBMED:17588513] [PUBMED:25175772] [PUBMED:19940261] [PUBMED:19775879] [PUBMED:23624913] [PUBMED:23657496] [PUBMED:23800009] [PUBMED:22708562] [PUBMED:26235645] [PUBMED:25833379] [PUBMED:26187467] [PUBMED:24699078] [PUBMED:26085183] [PUBMED:21883762] [PUBMED:23747565] [PUBMED:27002219] [PUBMED:27312108] [PUBMED:19436320] [PUBMED:23061719] [PUBMED:24457024] [PUBMED:24652853] [PUBMED:23732108] [PUBMED:22389392] [PUBMED:19754430] [PUBMED:19489725] [PUBMED:25815272]
Recognition of DNA damage by PCNA-containing replication complex [NCBI:1270368] [REACTOME:R-HSA-110314] [PUBMED:15916957] [PUBMED:12226657]
Synthesis of active ubiquitin: roles of E1 and E2 enzymes [NCBI:1457809] [REACTOME:R-HSA-8866652] [PUBMED:26235645] [PUBMED:24457024] [PUBMED:27002219] [PUBMED:17597759] [PUBMED:19940261] [PUBMED:6277905] [PUBMED:6305978]
Ubiquitin mediated proteolysis [NCBI:83056] [KEGG:hsa04120] [PUBMED:16405856] [PUBMED:12944364] [PUBMED:16922408] [PUBMED:17588513] [PUBMED:16922367] [PUBMED:16922370] [PUBMED:16816840]