full name
secretion associated Ras related GTPase 1B

synonyms
ANDD, CMRD, GTBPB, SARA2, SAR1B, ENSG00000152700

HGNC
HGNC:10535

Entrez Gene
Gene:51128

ENSEMBL
ENSG00000152700

location
chr: 5
start: 133936839
stop: 133968533
strand: -

OMIM
OMIM:607690: SAR1B (Autosomal recessive inheritance)
OMIM:246700: Chylomicron retention disease

transcripts
NM_016103.3
NM_001033503.2

pathways
Adaptive Immune System [NCBI:1269171] [REACTOME:R-HSA-1280218] [PUBMED:16551257] [PUBMED:21682741] [PUBMED:11861602]
Antigen Presentation: Folding, assembly and peptide loading of class I MHC [NCBI:1269194] [REACTOME:R-HSA-983170] [PUBMED:19178136] [PUBMED:18926908] [PUBMED:12495737] [PUBMED:15224092] [PUBMED:18641646]
Asparagine N-linked glycosylation [NCBI:1268714] [REACTOME:R-HSA-446203] [PUBMED:16807922] [PUBMED:19647993] [PUBMED:10580125] [PUBMED:19616933] [PUBMED:20301507] [PUBMED:20301244]
COPII (Coat Protein 2) Mediated Vesicle Transport [NCBI:1268727] [REACTOME:R-HSA-204005] [PUBMED:17316621] [PUBMED:11252894]
Cargo concentration in the ER [NCBI:1309087] [REACTOME:R-HSA-5694530] [PUBMED:18843296] [PUBMED:25619253] [PUBMED:22013193] [PUBMED:12941277] [PUBMED:12426382] [PUBMED:20533886] [PUBMED:23378591] [PUBMED:12819131] [PUBMED:21878990] [PUBMED:12941276]
Chylomicron-mediated lipid transport [NCBI:1270006] [REACTOME:R-HSA-174800]
Class I MHC mediated antigen processing & presentation [NCBI:1269192] [REACTOME:R-HSA-983169] [PUBMED:8717519] [PUBMED:17145306] [PUBMED:18926908] [PUBMED:17055423] [PUBMED:12495737] [PUBMED:18641646] [PUBMED:18243674]
ER to Golgi Anterograde Transport [NCBI:1268726] [REACTOME:R-HSA-199977] [PUBMED:11252894]
Immune System [NCBI:1269170] [REACTOME:R-HSA-168256]
Legionellosis [NCBI:469200] [KEGG:hsa05134] [PUBMED:19021631] [PUBMED:19157961] [PUBMED:20375353] [PUBMED:19478083] [PUBMED:18284575] [PUBMED:19386084] [PUBMED:19666608] [PUBMED:15972519] [PUBMED:18549456] [PUBMED:1721820] [PUBMED:17124169] [PUBMED:19687203] [PUBMED:18363881] [PUBMED:19343209] [PUBMED:20941588] [PUBMED:16824952] [PUBMED:18281405] [PUBMED:18048909] [PUBMED:16495539] [PUBMED:12427954]
Lipid digestion, mobilization, and transport [NCBI:1270002] [REACTOME:R-HSA-73923]
Lipoprotein metabolism [NCBI:1270005] [REACTOME:R-HSA-174824]
MHC class II antigen presentation [NCBI:1269200] [REACTOME:R-HSA-2132295] [PUBMED:19703008] [PUBMED:9316394] [PUBMED:11684289] [PUBMED:19217269] [PUBMED:8689559]
Membrane Trafficking [NCBI:1269877] [REACTOME:R-HSA-199991] [PUBMED:11031247]
Metabolism [NCBI:1269956] [REACTOME:R-HSA-1430728]
Metabolism of lipids and lipoproteins [NCBI:1270001] [REACTOME:R-HSA-556833]
Metabolism of proteins [NCBI:1268677] [REACTOME:R-HSA-392499]
Post-translational protein modification [NCBI:1268701] [REACTOME:R-HSA-597592]
Protein processing in endoplasmic reticulum [NCBI:167325] [KEGG:hsa04141] [PUBMED:20347046] [PUBMED:18023214] [PUBMED:20219571] [PUBMED:19491040] [PUBMED:20112977]
Regulation of cholesterol biosynthesis by SREBP (SREBF) [NCBI:1270038] [REACTOME:R-HSA-1655829] [PUBMED:15457548] [PUBMED:19933148] [PUBMED:18974038]
Transport to the Golgi and subsequent modification [NCBI:1268725] [REACTOME:R-HSA-948021] [PUBMED:12717434] [PUBMED:10412983] [PUBMED:3594573]
Vesicle-mediated transport [NCBI:1269876] [REACTOME:R-HSA-5653656]