full name
early growth response 1

synonyms
AT225, G0S30, KROX-24, NGFI-A, TIS8, ZIF-268, ZNF225, EGR1, ENSG00000120738

HGNC
HGNC:3238

Entrez Gene
Gene:1958

ENSEMBL
ENSG00000120738

location
chr: 5
start: 137801181
stop: 137805004
strand: +

transcripts
NM_001964.2

pathways
AGE-RAGE signaling pathway in diabetic complications [NCBI:1319988] [KEGG:hsa04933] [PUBMED:23776698] [PUBMED:15569303] [PUBMED:16894049] [PUBMED:18323529] [PUBMED:11375353] [PUBMED:21111800] [PUBMED:19404313] [PUBMED:20470857] [PUBMED:17005604] [PUBMED:23961320] [PUBMED:21261520] [PUBMED:11180401] [PUBMED:18922799] [PUBMED:21680901] [PUBMED:11684565] [PUBMED:21590515] [PUBMED:12709399] [PUBMED:20300563] [PUBMED:21440603] [PUBMED:22558488]
Apelin signaling pathway [NCBI:1492886] [KEGG:hsa04371] [PUBMED:23973488] [PUBMED:16182514] [PUBMED:21725702] [PUBMED:22842084] [PUBMED:27825851] [PUBMED:27650065] [PUBMED:22140623] [PUBMED:23943882] [PUBMED:26944568] [PUBMED:24055369] [PUBMED:26385179] [PUBMED:26143239] [PUBMED:22028387] [PUBMED:26254105] [PUBMED:26756969] [PUBMED:22995518] [PUBMED:27979574] [PUBMED:23924696] [PUBMED:21464822] [PUBMED:25914650] [PUBMED:24990699] [PUBMED:26607438] [PUBMED:25164121] [PUBMED:25275559] [PUBMED:25139773] [PUBMED:25931124] [PUBMED:19093215] [PUBMED:20539939] [PUBMED:25652330] [PUBMED:18272138] [PUBMED:23603510]
Calcineurin-regulated NFAT-dependent transcription in lymphocytes [NCBI:137993] [Pathway Interaction Database:nfat_tfpathway] [PUBMED:11254715] [PUBMED:11356833] [PUBMED:12121669] [PUBMED:10878360] [PUBMED:11786533] [PUBMED:8284217] [PUBMED:10816557] [PUBMED:11956291] [PUBMED:7510691] [PUBMED:9195954] [PUBMED:8240350] [PUBMED:12452838] [PUBMED:8623163] [PUBMED:15834410] [PUBMED:10894164] [PUBMED:10970869] [PUBMED:10755616] [PUBMED:14607827] [PUBMED:12705856] [PUBMED:12086671] [PUBMED:7982959] [PUBMED:9047239] [PUBMED:12374808] [PUBMED:14573767] [PUBMED:12560487] [PUBMED:10570264] [PUBMED:8397339] [PUBMED:12055628] [PUBMED:15308098] [PUBMED:12065418] [PUBMED:7891702] [PUBMED:7749982] [PUBMED:14973438] [PUBMED:8674125] [PUBMED:16873067] [PUBMED:12453415] [PUBMED:8441422] [PUBMED:1737937] [PUBMED:10671476] [PUBMED:8376940] [PUBMED:9545284]
Cytokine Signaling in Immune system [NCBI:1269310] [REACTOME:R-HSA-1280215] [PUBMED:12613569]
Downstream signaling in naive CD8+ T cells [NCBI:138018] [Pathway Interaction Database:cd8tcrdownstreampathway] [PUBMED:293720] [PUBMED:7935374] [PUBMED:12065418] [PUBMED:8566027] [PUBMED:12917261] [PUBMED:8394352] [PUBMED:8441422] [PUBMED:1386920] [PUBMED:8617294] [PUBMED:12732656] [PUBMED:7889942] [PUBMED:1737937] [PUBMED:1381507] [PUBMED:16210616] [PUBMED:11927626] [PUBMED:10477579] [PUBMED:10206983] [PUBMED:8376940] [PUBMED:9395475] [PUBMED:12972619] [PUBMED:8394845] [PUBMED:11485747] [PUBMED:15814665] [PUBMED:14645153] [PUBMED:2119889] [PUBMED:8208531] [PUBMED:10970869] [PUBMED:8612134] [PUBMED:8623163] [PUBMED:16237086] [PUBMED:16585578] [PUBMED:10544201] [PUBMED:8397339] [PUBMED:14605368] [PUBMED:12560487] [PUBMED:7982959]
ErbB1 downstream signaling [NCBI:138057] [Pathway Interaction Database:erbb1_downstream_pathway] [PUBMED:1330321] [PUBMED:7939666] [PUBMED:9448004] [PUBMED:3497813] [PUBMED:7680434] [PUBMED:18567582] [PUBMED:12503606] [PUBMED:12183455] [PUBMED:8073291] [PUBMED:17563371] [PUBMED:8378775] [PUBMED:19219045] [PUBMED:1990291] [PUBMED:15550174] [PUBMED:16508002] [PUBMED:17881733] [PUBMED:11278353] [PUBMED:9889102] [PUBMED:14699061] [PUBMED:8248196] [PUBMED:8262053] [PUBMED:11319218] [PUBMED:19595761] [PUBMED:17360704] [PUBMED:15048123] [PUBMED:19341767] [PUBMED:9837959] [PUBMED:14993287] [PUBMED:19710016] [PUBMED:18516090] [PUBMED:9733714] [PUBMED:8052307] [PUBMED:10567369] [PUBMED:9335504] [PUBMED:9580112] [PUBMED:11018520] [PUBMED:10499589] [PUBMED:19706684] [PUBMED:8910287] [PUBMED:10469645] [PUBMED:11073940] [PUBMED:9315636] [PUBMED:2189103] [PUBMED:14765121] [PUBMED:14970219] [PUBMED:8332195] [PUBMED:16239230] [PUBMED:8621729] [PUBMED:11889038] [PUBMED:11029289] [PUBMED:11152283] [PUBMED:8071311] [PUBMED:12932319] [PUBMED:19541618] [PUBMED:2123453] [PUBMED:9384584] [PUBMED:8140422] [PUBMED:10644690] [PUBMED:18156174] [PUBMED:15718470] [PUBMED:12172553] [PUBMED:10082559] [PUBMED:17079732] [PUBMED:12446727] [PUBMED:9989263] [PUBMED:12551925] [PUBMED:10856237] [PUBMED:8013650] [PUBMED:7600581] [PUBMED:8688081] [PUBMED:8397445] [PUBMED:16135787] [PUBMED:7637810] [PUBMED:9438848] [PUBMED:12515821] [PUBMED:12881422] [PUBMED:9305638] [PUBMED:15284024] [PUBMED:3136398] [PUBMED:10597268] [PUBMED:10648629] [PUBMED:9790194] [PUBMED:9797479] [PUBMED:16093354] [PUBMED:7741752] [PUBMED:10891480] [PUBMED:17052213] [PUBMED:8221888] [PUBMED:9593664] [PUBMED:16892053] [PUBMED:8413226] [PUBMED:9407138] [PUBMED:9710644] [PUBMED:8248197] [PUBMED:12414794] [PUBMED:1653949] [PUBMED:12181570] [PUBMED:9550702] [PUBMED:12110590] [PUBMED:10400627] [PUBMED:9927426] [PUBMED:12242303] [PUBMED:10480933] [PUBMED:9665134] [PUBMED:11238956] [PUBMED:16984645] [PUBMED:7761091] [PUBMED:17322878] [PUBMED:12640115] [PUBMED:14963038] [PUBMED:17486115] [PUBMED:8503013] [PUBMED:16155590] [PUBMED:16628218] [PUBMED:1406636] [PUBMED:9430728] [PUBMED:19401591] [PUBMED:17053785] [PUBMED:7992057] [PUBMED:14609431] [PUBMED:9346240] [PUBMED:8626780] [PUBMED:8940018] [PUBMED:12454019] [PUBMED:10441128] [PUBMED:14747473] [PUBMED:11777939] [PUBMED:8614832] [PUBMED:8378774] [PUBMED:19121340] [PUBMED:18775988] [PUBMED:15039778] [PUBMED:9770464] [PUBMED:10567531] [PUBMED:8180183] [PUBMED:10675331] [PUBMED:1545823] [PUBMED:7958858] [PUBMED:11948693] [PUBMED:2109185] [PUBMED:8942998] [PUBMED:1637333] [PUBMED:14690430] [PUBMED:11134016] [PUBMED:12429840] [PUBMED:8621573] [PUBMED:7600582] [PUBMED:8226933] [PUBMED:10201527] [PUBMED:12832467] [PUBMED:3492494] [PUBMED:15034142] [PUBMED:9596579] [PUBMED:7889942] [PUBMED:8524316] [PUBMED:7731720] [PUBMED:8386592] [PUBMED:16407412] [PUBMED:6334806] [PUBMED:11703925] [PUBMED:11099046] [PUBMED:7876145] [PUBMED:14498832]
Glucocorticoid receptor regulatory network [NCBI:138014] [Pathway Interaction Database:reg_gr_pathway] [PUBMED:8943293] [PUBMED:1708774] [PUBMED:15826950] [PUBMED:11027313] [PUBMED:12118039] [PUBMED:9388207] [PUBMED:11751894] [PUBMED:12151000] [PUBMED:9765258] [PUBMED:9407028] [PUBMED:19074285] [PUBMED:2838908] [PUBMED:15817653] [PUBMED:9722596] [PUBMED:12917342] [PUBMED:1387550] [PUBMED:10974006] [PUBMED:15790729] [PUBMED:10825196] [PUBMED:10623828] [PUBMED:2169352] [PUBMED:9315653] [PUBMED:7759501] [PUBMED:8290595] [PUBMED:2905764] [PUBMED:12351702] [PUBMED:11080152] [PUBMED:8428574] [PUBMED:9215863] [PUBMED:15459252] [PUBMED:10400612] [PUBMED:9426156] [PUBMED:17440046] [PUBMED:18838540] [PUBMED:2169353] [PUBMED:10820245] [PUBMED:12511605] [PUBMED:2586521] [PUBMED:1740658] [PUBMED:11555652] [PUBMED:11562347] [PUBMED:9482836] [PUBMED:18337589] [PUBMED:10958685] [PUBMED:9388192] [PUBMED:15834420] [PUBMED:15657031] [PUBMED:8878484] [PUBMED:10760263] [PUBMED:12730237] [PUBMED:8702844] [PUBMED:2169351] [PUBMED:17215482] [PUBMED:8898375]
HTLV-I infection [NCBI:373901] [KEGG:hsa05166] [PUBMED:17446673] [PUBMED:16436385] [PUBMED:14686485] [PUBMED:19861996] [PUBMED:19092975] [PUBMED:11325603] [PUBMED:16155602] [PUBMED:12910251] [PUBMED:16155605] [PUBMED:16036567] [PUBMED:11244044] [PUBMED:18702816] [PUBMED:15569630] [PUBMED:21114861] [PUBMED:16155611] [PUBMED:17384582] [PUBMED:16155608] [PUBMED:10602469] [PUBMED:19014483] [PUBMED:9325311]
Immune System [NCBI:1269170] [REACTOME:R-HSA-168256]
Interferon Signaling [NCBI:1269311] [REACTOME:R-HSA-913531] [PUBMED:18929502] [PUBMED:15607020] [PUBMED:15864272] [PUBMED:14525967] [PUBMED:19059436]
Interferon alpha/beta signaling [NCBI:1269312] [REACTOME:R-HSA-909733] [PUBMED:8621447] [PUBMED:8605876] [PUBMED:8702790] [PUBMED:17969444]
Prion diseases [NCBI:101144] [KEGG:hsa05020] [PUBMED:15695097] [PUBMED:18558863] [PUBMED:11592845] [PUBMED:15528202] [PUBMED:17051207] [PUBMED:18245809] [PUBMED:14705136] [PUBMED:10398674] [PUBMED:15890824] [PUBMED:14661267] [PUBMED:15611724] [PUBMED:15342004] [PUBMED:18391177] [PUBMED:17085779] [PUBMED:12850426]
Regulation of Androgen receptor activity [NCBI:138027] [Pathway Interaction Database:ar_tf_pathway] [PUBMED:15650026] [PUBMED:17045208] [PUBMED:10364196] [PUBMED:16860317] [PUBMED:10611280] [PUBMED:10930412] [PUBMED:1525041] [PUBMED:10779504] [PUBMED:12514133] [PUBMED:1985913] [PUBMED:11931767] [PUBMED:17011549] [PUBMED:15640443] [PUBMED:16322096] [PUBMED:15923603] [PUBMED:14985354] [PUBMED:15743818] [PUBMED:12949936] [PUBMED:11994312] [PUBMED:10567371] [PUBMED:11875111] [PUBMED:15604291] [PUBMED:12890669] [PUBMED:14729952] [PUBMED:9211894] [PUBMED:9162033] [PUBMED:16705743] [PUBMED:16849544] [PUBMED:16923962] [PUBMED:11591700] [PUBMED:16051670] [PUBMED:8643509] [PUBMED:17108144] [PUBMED:16914734] [PUBMED:12682292] [PUBMED:3353726] [PUBMED:11585838] [PUBMED:16282370] [PUBMED:10381882] [PUBMED:15199155] [PUBMED:16455820] [PUBMED:14612401] [PUBMED:10625666] [PUBMED:17679089] [PUBMED:16461774]
Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) [NCBI:137930] [Pathway Interaction Database:met_pathway] [PUBMED:10793146] [PUBMED:8906793] [PUBMED:11929826] [PUBMED:10022866] [PUBMED:11532961] [PUBMED:12475979] [PUBMED:1718989] [PUBMED:1846706] [PUBMED:10970810] [PUBMED:10516287] [PUBMED:12138161] [PUBMED:11046147] [PUBMED:18073207] [PUBMED:12951049] [PUBMED:15494312] [PUBMED:9001234] [PUBMED:11352916] [PUBMED:11896055] [PUBMED:9440692] [PUBMED:8607979] [PUBMED:12244132] [PUBMED:11162460] [PUBMED:11809798] [PUBMED:9693375] [PUBMED:14636584] [PUBMED:17297451] [PUBMED:17682062] [PUBMED:19628037] [PUBMED:11069926] [PUBMED:18819921] [PUBMED:16423831] [PUBMED:10558875] [PUBMED:16858414] [PUBMED:10995442] [PUBMED:20332103] [PUBMED:11146548] [PUBMED:18346875] [PUBMED:17894413] [PUBMED:9252406] [PUBMED:17635922] [PUBMED:11134526] [PUBMED:2005882] [PUBMED:19609305] [PUBMED:8380735] [PUBMED:16537482] [PUBMED:10618718] [PUBMED:9591773] [PUBMED:12894582] [PUBMED:9748249] [PUBMED:11741535] [PUBMED:17881575] [PUBMED:10713050] [PUBMED:1655790] [PUBMED:11784715] [PUBMED:10753869] [PUBMED:10713700] [PUBMED:11118451] [PUBMED:16952352] [PUBMED:15314156] [PUBMED:19272169] [PUBMED:12802068] [PUBMED:17363898] [PUBMED:7513258] [PUBMED:1827664] [PUBMED:2541345] [PUBMED:8387483] [PUBMED:16620780] [PUBMED:11445578] [PUBMED:10734310] [PUBMED:16227611] [PUBMED:12941962] [PUBMED:15735664] [PUBMED:19071214] [PUBMED:7731718] [PUBMED:19289496] [PUBMED:11438654] [PUBMED:11896612] [PUBMED:11894096] [PUBMED:11896575] [PUBMED:7499247] [PUBMED:12147692] [PUBMED:11948414] [PUBMED:19881549] [PUBMED:19525225] [PUBMED:14684163] [PUBMED:17055484] [PUBMED:9668053] [PUBMED:10531383] [PUBMED:9681449] [PUBMED:1655405] [PUBMED:12686592] [PUBMED:19109251] [PUBMED:10679787] [PUBMED:9487126] [PUBMED:9886295] [PUBMED:12058075] [PUBMED:15452053] [PUBMED:9184210] [PUBMED:10871282] [PUBMED:17329361] [PUBMED:2554238]
Signaling events mediated by PRL [NCBI:137969] [Pathway Interaction Database:prlsignalingeventspathway] [PUBMED:11447212] [PUBMED:16508789] [PUBMED:12235145] [PUBMED:11355880] [PUBMED:16540666] [PUBMED:8196618] [PUBMED:14643450] [PUBMED:11278933] [PUBMED:16472776]
Trk receptor signaling mediated by PI3K and PLC-gamma [NCBI:137967] [Pathway Interaction Database:pi3kplctrkpathway] [PUBMED:11136977] [PUBMED:11864996] [PUBMED:8663990] [PUBMED:12367511] [PUBMED:9094314] [PUBMED:10330161] [PUBMED:11953455] [PUBMED:7886457] [PUBMED:16319926] [PUBMED:10102273] [PUBMED:11418861] [PUBMED:10729337] [PUBMED:9346240] [PUBMED:10677043] [PUBMED:15702476] [PUBMED:15207235] [PUBMED:9637919]
Trk receptor signaling mediated by the MAPK pathway [NCBI:138044] [Pathway Interaction Database:mapktrkpathway] [PUBMED:15632082] [PUBMED:11050086] [PUBMED:9687510] [PUBMED:17003042] [PUBMED:7889942] [PUBMED:11150318] [PUBMED:11331872] [PUBMED:8387505] [PUBMED:1386920] [PUBMED:8394352] [PUBMED:11278445] [PUBMED:15917464] [PUBMED:9560161] [PUBMED:11073940] [PUBMED:12826611] [PUBMED:16157584] [PUBMED:15024033] [PUBMED:9528766] [PUBMED:12011113] [PUBMED:10330161] [PUBMED:11544482] [PUBMED:12367506] [PUBMED:12917366]