full name
catenin alpha 1

synonyms
CAP102, CTNNA1, ENSG00000044115

HGNC
HGNC:2509

Entrez Gene
Gene:1495

ENSEMBL
ENSG00000044115

location
chr: 5
start: 138089075
stop: 138270723
strand: +

OMIM
OMIM:116805: CTNNA1
OMIM:608970: Macular dystrophy, patterned, 2

transcripts
NM_001903.2

pathways
Adherens junction [NCBI:83070] [KEGG:hsa04520] [PUBMED:11703922] [PUBMED:10890911] [PUBMED:15551862] [PUBMED:15561584] [PUBMED:10959047] [PUBMED:11984870] [PUBMED:10204118] [PUBMED:15489912] [PUBMED:14623871] [PUBMED:15001769] [PUBMED:12640114] [PUBMED:12665527] [PUBMED:11171368]
Adherens junctions interactions [NCBI:1270234] [REACTOME:R-HSA-418990] [PUBMED:19081036] [PUBMED:18365233]
Arf6 trafficking events [NCBI:137954] [Pathway Interaction Database:arf6_traffickingpathway] [PUBMED:10748097] [PUBMED:15590645] [PUBMED:15980073] [PUBMED:19644450] [PUBMED:16461286] [PUBMED:14675422] [PUBMED:16139226] [PUBMED:12589044] [PUBMED:15802264] [PUBMED:14585928] [PUBMED:17664335] [PUBMED:17719203] [PUBMED:12960436] [PUBMED:12447393] [PUBMED:11535619] [PUBMED:12657640] [PUBMED:16280360] [PUBMED:9314528] [PUBMED:19211056] [PUBMED:11533043] [PUBMED:12847086] [PUBMED:15146059] [PUBMED:9685333] [PUBMED:12925709] [PUBMED:15231847] [PUBMED:12810696] [PUBMED:14662749] [PUBMED:16030257] [PUBMED:12379803] [PUBMED:15775968] [PUBMED:11532961] [PUBMED:8769418]
Arrhythmogenic right ventricular cardiomyopathy (ARVC) [NCBI:117293] [KEGG:hsa05412] [PUBMED:16823481] [PUBMED:19205777] [PUBMED:11716909] [PUBMED:12270949] [PUBMED:18382419] [PUBMED:16101641] [PUBMED:16124859] [PUBMED:17413274]
Bacterial invasion of epithelial cells [NCBI:149807] [KEGG:hsa05100] [PUBMED:17298394] [PUBMED:16406780] [PUBMED:19185531] [PUBMED:19157959] [PUBMED:17719540] [PUBMED:19296488]
CDC42 signaling events [NCBI:137994] [Pathway Interaction Database:cdc42_pathway] [PUBMED:7629060] [PUBMED:7652575] [PUBMED:8653792] [PUBMED:18448434] [PUBMED:19822663] [PUBMED:19454477] [PUBMED:18662680] [PUBMED:15882626] [PUBMED:11948177] [PUBMED:9860974] [PUBMED:15225553] [PUBMED:8643625] [PUBMED:8107774] [PUBMED:8670801] [PUBMED:8034624] [PUBMED:10934474] [PUBMED:10734320] [PUBMED:17522712] [PUBMED:11525734] [PUBMED:15649357] [PUBMED:10473551] [PUBMED:16157700] [PUBMED:9822598] [PUBMED:15723051] [PUBMED:7600582] [PUBMED:18319301] [PUBMED:9042860] [PUBMED:10613909] [PUBMED:17580073] [PUBMED:12745076] [PUBMED:16253996] [PUBMED:10840034] [PUBMED:10360579] [PUBMED:11907268] [PUBMED:10934475] [PUBMED:10219243] [PUBMED:17038317] [PUBMED:8910292] [PUBMED:9403696] [PUBMED:11285260] [PUBMED:10995437] [PUBMED:9368021] [PUBMED:14970210] [PUBMED:9694656] [PUBMED:14505571] [PUBMED:17115031] [PUBMED:9317150] [PUBMED:14653992] [PUBMED:17081755] [PUBMED:12676083] [PUBMED:18216334] [PUBMED:19826000] [PUBMED:8702968] [PUBMED:11304531] [PUBMED:10973943] [PUBMED:11309380] [PUBMED:18586681] [PUBMED:15479449] [PUBMED:19097998] [PUBMED:16892055] [PUBMED:17244649] [PUBMED:8625410] [PUBMED:8497321] [PUBMED:15485841] [PUBMED:16407834] [PUBMED:11804587] [PUBMED:9867866] [PUBMED:10747870] [PUBMED:7600581] [PUBMED:12610628] [PUBMED:19435802] [PUBMED:15572110] [PUBMED:7592586] [PUBMED:11696321] [PUBMED:10559936]
CDO in myogenesis [NCBI:1270336] [REACTOME:R-HSA-375170] [PUBMED:15923648]
Cell junction organization [NCBI:1270232] [REACTOME:R-HSA-446728]
Cell-Cell communication [NCBI:1270231] [REACTOME:R-HSA-1500931] [PUBMED:20554646] [PUBMED:12598678] [PUBMED:17766183] [PUBMED:18837673] [PUBMED:16691243] [PUBMED:1616050]
Cell-cell junction organization [NCBI:1270233] [REACTOME:R-HSA-421270] [PUBMED:16487793] [PUBMED:1616050] [PUBMED:19081036] [PUBMED:16537104] [PUBMED:17854762]
Developmental Biology [NCBI:1270302] [REACTOME:R-HSA-1266738]
E-cadherin signaling in keratinocytes [NCBI:138002] [Pathway Interaction Database:ecadherin_keratinocyte_pathway] [PUBMED:16036919] [PUBMED:17439945] [PUBMED:10969083] [PUBMED:15872086] [PUBMED:17124506] [PUBMED:10660044] [PUBMED:8063817] [PUBMED:18754040] [PUBMED:19158393] [PUBMED:9628900] [PUBMED:12652652] [PUBMED:14647292] [PUBMED:12147707] [PUBMED:18065418] [PUBMED:17242406] [PUBMED:12782654] [PUBMED:12417594] [PUBMED:11777936]
E-cadherin signaling in the nascent adherens junction [NCBI:138005] [Pathway Interaction Database:ecadherin_nascentaj_pathway] [PUBMED:16371509] [PUBMED:9694656] [PUBMED:9214391] [PUBMED:17620337] [PUBMED:7969453] [PUBMED:11882288] [PUBMED:19158278] [PUBMED:11716761] [PUBMED:10402472] [PUBMED:15263019] [PUBMED:12427869] [PUBMED:11457821] [PUBMED:6976838] [PUBMED:10037790] [PUBMED:10660044] [PUBMED:15857834] [PUBMED:10202138] [PUBMED:10980705] [PUBMED:15159390] [PUBMED:2349235] [PUBMED:19114658] [PUBMED:14585958] [PUBMED:18632982] [PUBMED:12432063] [PUBMED:17261850] [PUBMED:10383446] [PUBMED:11329369] [PUBMED:14699157] [PUBMED:7954478] [PUBMED:10629228] [PUBMED:8207061] [PUBMED:15556934] [PUBMED:10473551] [PUBMED:12370292] [PUBMED:14610055] [PUBMED:16170364] [PUBMED:12770907] [PUBMED:17553930] [PUBMED:17164293] [PUBMED:2788574] [PUBMED:9512503] [PUBMED:10201395] [PUBMED:15254236] [PUBMED:15024035] [PUBMED:12447393] [PUBMED:11744701] [PUBMED:14668487] [PUBMED:18187454]
Endometrial cancer [NCBI:83109] [KEGG:hsa05213] [PUBMED:14747944] [PUBMED:11431710] [PUBMED:7585656] [PUBMED:16508724] [PUBMED:15284264] [PUBMED:17028294] [PUBMED:16248975] [PUBMED:15947972]
Hippo signaling pathway [NCBI:749777] [KEGG:hsa04390] [PUBMED:18955139] [PUBMED:20439427] [PUBMED:20951342] [PUBMED:21138973] [PUBMED:18328423] [PUBMED:21324984] [PUBMED:23034192] [PUBMED:21808241] [PUBMED:17975546] [PUBMED:22750148] [PUBMED:21084559] [PUBMED:19846288] [PUBMED:22895435] [PUBMED:22683405] [PUBMED:22658639] [PUBMED:22153608] [PUBMED:20945341] [PUBMED:22830020] [PUBMED:21874053] [PUBMED:21376238]
Leukocyte transendothelial migration [NCBI:83083] [KEGG:hsa04670] [PUBMED:15629883] [PUBMED:10975856] [PUBMED:14976004] [PUBMED:15265790] [PUBMED:15173832] [PUBMED:12540948] [PUBMED:15771581] [PUBMED:15604886] [PUBMED:14977592]
Myogenesis [NCBI:1270335] [REACTOME:R-HSA-525793]
N-cadherin signaling events [NCBI:137919] [Pathway Interaction Database:ncadherinpathway] [PUBMED:16319177] [PUBMED:19075000] [PUBMED:15121175] [PUBMED:15226396] [PUBMED:17765222] [PUBMED:7885471] [PUBMED:11086998] [PUBMED:2318342] [PUBMED:8050374] [PUBMED:9655503] [PUBMED:7962102] [PUBMED:7599959] [PUBMED:17459003] [PUBMED:9852580] [PUBMED:9052794] [PUBMED:17005551] [PUBMED:1837087] [PUBMED:1639850] [PUBMED:16176974] [PUBMED:16807326] [PUBMED:15716354] [PUBMED:8707857] [PUBMED:19162191] [PUBMED:12099895] [PUBMED:8113807] [PUBMED:16228908] [PUBMED:17538019] [PUBMED:11056534] [PUBMED:11809840] [PUBMED:11571292] [PUBMED:12377785] [PUBMED:8909549] [PUBMED:3780667] [PUBMED:9655504] [PUBMED:14610057] [PUBMED:15569714] [PUBMED:15662031] [PUBMED:15809310] [PUBMED:15247242] [PUBMED:2762814] [PUBMED:17289573] [PUBMED:17921113] [PUBMED:9712659] [PUBMED:12578907] [PUBMED:16515543] [PUBMED:15034585] [PUBMED:11106648] [PUBMED:11228159] [PUBMED:9786960] [PUBMED:12604612] [PUBMED:11466312] [PUBMED:11238727] [PUBMED:12640032] [PUBMED:1487503] [PUBMED:15383621] [PUBMED:8816706] [PUBMED:17481398] [PUBMED:9545083] [PUBMED:14657280] [PUBMED:12213839] [PUBMED:10930450]
Nectin adhesion pathway [NCBI:138054] [Pathway Interaction Database:nectin_pathway] [PUBMED:15504743] [PUBMED:9845526] [PUBMED:10225955] [PUBMED:12054561] [PUBMED:10974003] [PUBMED:18547333] [PUBMED:14526080] [PUBMED:17965016] [PUBMED:16472674] [PUBMED:12687012] [PUBMED:15263019] [PUBMED:16679515] [PUBMED:15485841] [PUBMED:15857834] [PUBMED:16216929] [PUBMED:10744716] [PUBMED:15277544] [PUBMED:10617658] [PUBMED:16128743] [PUBMED:12400007] [PUBMED:12694536] [PUBMED:18505795] [PUBMED:11544254] [PUBMED:11024295]
Pathways in cancer [NCBI:83105] [KEGG:hsa05200] [PUBMED:12244301] [PUBMED:15156182] [PUBMED:16899407] [PUBMED:12621137] [PUBMED:21193867] [PUBMED:16001072] [PUBMED:11707511] [PUBMED:11253051] [PUBMED:11071626] [PUBMED:17251915] [PUBMED:11736900] [PUBMED:16557281] [PUBMED:16699851] [PUBMED:16189702] [PUBMED:11902573] [PUBMED:16555243] [PUBMED:8069858] [PUBMED:15310786] [PUBMED:9834202] [PUBMED:16700615] [PUBMED:12545153] [PUBMED:15656799] [PUBMED:12154354] [PUBMED:11895903] [PUBMED:11527574] [PUBMED:16326109] [PUBMED:16339096] [PUBMED:11160144] [PUBMED:15724144] [PUBMED:12951584] [PUBMED:10647931] [PUBMED:16881963] [PUBMED:15557758] [PUBMED:11477132] [PUBMED:15721476] [PUBMED:15625120] [PUBMED:16236521] [PUBMED:14967450] [PUBMED:15942304] [PUBMED:17287871] [PUBMED:14634372] [PUBMED:15573119] [PUBMED:15009714] [PUBMED:16112428] [PUBMED:15611513] [PUBMED:16001050] [PUBMED:15349822] [PUBMED:16551846] [PUBMED:15978322] [PUBMED:15774796] [PUBMED:16352814] [PUBMED:12951588] [PUBMED:10944551] [PUBMED:10740269] [PUBMED:15639402] [PUBMED:12407699] [PUBMED:11130178] [PUBMED:15109562] [PUBMED:11170304] [PUBMED:11276000] [PUBMED:9643506] [PUBMED:16248975] [PUBMED:16242838] [PUBMED:12946833] [PUBMED:11559746] [PUBMED:9196022] [PUBMED:12079267] [PUBMED:15468170] [PUBMED:16064138] [PUBMED:14580692] [PUBMED:15082523] [PUBMED:15551095] [PUBMED:17062879] [PUBMED:17211469] [PUBMED:11720739] [PUBMED:12588368] [PUBMED:11057895] [PUBMED:9422516] [PUBMED:12894244] [PUBMED:15479695] [PUBMED:16189154] [PUBMED:12878745] [PUBMED:11900250] [PUBMED:11103787] [PUBMED:15122209] [PUBMED:12711111] [PUBMED:12243753] [PUBMED:16306523] [PUBMED:16702400] [PUBMED:15270885] [PUBMED:14685170] [PUBMED:14586404] [PUBMED:11078609] [PUBMED:15284264] [PUBMED:10505543] [PUBMED:11223406] [PUBMED:14982876] [PUBMED:12648469] [PUBMED:12867060] [PUBMED:15711891] [PUBMED:12094241] [PUBMED:16642045] [PUBMED:11463388] [PUBMED:12762887] [PUBMED:15746962] [PUBMED:15823750] [PUBMED:16750612] [PUBMED:16484590] [PUBMED:11459867] [PUBMED:16146838] [PUBMED:14556242] [PUBMED:15947972] [PUBMED:12563308] [PUBMED:16946003] [PUBMED:15948971] [PUBMED:11407945] [PUBMED:12737309] [PUBMED:16095998] [PUBMED:12351585] [PUBMED:24508914] [PUBMED:12084351] [PUBMED:11807782] [PUBMED:14695152] [PUBMED:10453277] [PUBMED:17554387] [PUBMED:15841168] [PUBMED:12616528] [PUBMED:10403855] [PUBMED:16054233] [PUBMED:16474624] [PUBMED:16822996] [PUBMED:17028294] [PUBMED:11224709] [PUBMED:11750244] [PUBMED:11905738] [PUBMED:15719031] [PUBMED:10843728] [PUBMED:16110317] [PUBMED:11721960] [PUBMED:12741677] [PUBMED:7585656] [PUBMED:12801837] [PUBMED:16551847] [PUBMED:12459728] [PUBMED:11431710] [PUBMED:12468433] [PUBMED:11165748] [PUBMED:16042571] [PUBMED:16508724] [PUBMED:15000146] [PUBMED:17149381] [PUBMED:15948711] [PUBMED:14747944] [PUBMED:14737121] [PUBMED:12379883] [PUBMED:17158541] [PUBMED:12850530] [PUBMED:10835690] [PUBMED:16870043]
RAC1 signaling pathway [NCBI:169355] [Pathway Interaction Database:rac1_pathway] [PUBMED:19158278] [PUBMED:16702231] [PUBMED:16440308] [PUBMED:14765121] [PUBMED:12453877] [PUBMED:12657629] [PUBMED:9799233] [PUBMED:9694656] [PUBMED:9317150] [PUBMED:14970210] [PUBMED:8305740] [PUBMED:8805275] [PUBMED:17178910] [PUBMED:11060298] [PUBMED:11304531] [PUBMED:11804587] [PUBMED:11470914] [PUBMED:11309380] [PUBMED:17244649] [PUBMED:11021801] [PUBMED:7592586] [PUBMED:15681696] [PUBMED:7744004] [PUBMED:15225553] [PUBMED:10559936] [PUBMED:19917258] [PUBMED:7600581] [PUBMED:19363480] [PUBMED:18423204] [PUBMED:20097736] [PUBMED:19852956] [PUBMED:12181570] [PUBMED:19822663] [PUBMED:7652575] [PUBMED:7629060] [PUBMED:8107774] [PUBMED:16636067] [PUBMED:9042860] [PUBMED:12213441] [PUBMED:10679324] [PUBMED:12682053] [PUBMED:18198193] [PUBMED:16542153] [PUBMED:7600582] [PUBMED:18948007] [PUBMED:18319301] [PUBMED:10559253] [PUBMED:17115053] [PUBMED:10473551] [PUBMED:17682062] [PUBMED:17164293] [PUBMED:15557278] [PUBMED:15677464] [PUBMED:16837009] [PUBMED:12796474] [PUBMED:10559863] [PUBMED:9535855] [PUBMED:8910292] [PUBMED:11432831] [PUBMED:17981134] [PUBMED:16762923] [PUBMED:8798539] [PUBMED:18160398] [PUBMED:16099876] [PUBMED:14681219]
RHO GTPase Effectors [NCBI:1269509] [REACTOME:R-HSA-195258] [PUBMED:9694656] [PUBMED:18066052] [PUBMED:11018042] [PUBMED:10470034] [PUBMED:8702756] [PUBMED:21730051] [PUBMED:8571126] [PUBMED:19513348] [PUBMED:17244649] [PUBMED:11145705] [PUBMED:24128008] [PUBMED:23716662] [PUBMED:8617235] [PUBMED:8543060] [PUBMED:11804587] [PUBMED:24969695] [PUBMED:12635176] [PUBMED:12778124] [PUBMED:18006505] [PUBMED:1660188] [PUBMED:21351730] [PUBMED:16507994] [PUBMED:14595335] [PUBMED:10072071] [PUBMED:10591629] [PUBMED:10753910] [PUBMED:23875749] [PUBMED:17151359] [PUBMED:10652353] [PUBMED:12221077] [PUBMED:10559936] [PUBMED:12783890] [PUBMED:11948177] [PUBMED:18237546] [PUBMED:16079795] [PUBMED:10924361] [PUBMED:14514689] [PUBMED:8107774] [PUBMED:8756646] [PUBMED:16979770] [PUBMED:16636067] [PUBMED:9751706] [PUBMED:10619026] [PUBMED:23444367] [PUBMED:15546864] [PUBMED:12473120] [PUBMED:8816443] [PUBMED:9199170] [PUBMED:12514133] [PUBMED:16762923] [PUBMED:12110184] [PUBMED:16431929] [PUBMED:10975528] [PUBMED:10940294] [PUBMED:9535855] [PUBMED:7559638] [PUBMED:11162552] [PUBMED:19737400] [PUBMED:9988689] [PUBMED:12732141] [PUBMED:8798539] [PUBMED:24914801] [PUBMED:11689693] [PUBMED:8769096] [PUBMED:9368021]
RHO GTPases activate IQGAPs [NCBI:1269516] [REACTOME:R-HSA-5626467] [PUBMED:21730051] [PUBMED:17244649] [PUBMED:8756646] [PUBMED:11948177] [PUBMED:22182509] [PUBMED:9199170] [PUBMED:8798539] [PUBMED:9368021]
Signal Transduction [NCBI:1269379] [REACTOME:R-HSA-162582] [PUBMED:17604717] [PUBMED:19648010] [PUBMED:16260143] [PUBMED:11742412] [PUBMED:19536106] [PUBMED:15863030] [PUBMED:19379690] [PUBMED:19458711] [PUBMED:19935667] [PUBMED:21252999] [PUBMED:15520807] [PUBMED:17496910] [PUBMED:15450248] [PUBMED:18043707] [PUBMED:16939974] [PUBMED:19762341] [PUBMED:18483217] [PUBMED:17084981] [PUBMED:21781017] [PUBMED:19619488]
Signaling by Rho GTPases [NCBI:1269507] [REACTOME:R-HSA-194315] [PUBMED:16212495] [PUBMED:15630019]
Signaling by VEGF [NCBI:1269480] [REACTOME:R-HSA-194138] [PUBMED:15585754] [PUBMED:13678960] [PUBMED:16336962] [PUBMED:16835467]
Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) [NCBI:137930] [Pathway Interaction Database:met_pathway] [PUBMED:10793146] [PUBMED:8906793] [PUBMED:11929826] [PUBMED:10022866] [PUBMED:11532961] [PUBMED:12475979] [PUBMED:1718989] [PUBMED:1846706] [PUBMED:10970810] [PUBMED:10516287] [PUBMED:12138161] [PUBMED:11046147] [PUBMED:18073207] [PUBMED:12951049] [PUBMED:15494312] [PUBMED:9001234] [PUBMED:11352916] [PUBMED:11896055] [PUBMED:9440692] [PUBMED:8607979] [PUBMED:12244132] [PUBMED:11162460] [PUBMED:11809798] [PUBMED:9693375] [PUBMED:14636584] [PUBMED:17297451] [PUBMED:17682062] [PUBMED:19628037] [PUBMED:11069926] [PUBMED:18819921] [PUBMED:16423831] [PUBMED:10558875] [PUBMED:16858414] [PUBMED:10995442] [PUBMED:20332103] [PUBMED:11146548] [PUBMED:18346875] [PUBMED:17894413] [PUBMED:9252406] [PUBMED:17635922] [PUBMED:11134526] [PUBMED:2005882] [PUBMED:19609305] [PUBMED:8380735] [PUBMED:16537482] [PUBMED:10618718] [PUBMED:9591773] [PUBMED:12894582] [PUBMED:9748249] [PUBMED:11741535] [PUBMED:17881575] [PUBMED:10713050] [PUBMED:1655790] [PUBMED:11784715] [PUBMED:10753869] [PUBMED:10713700] [PUBMED:11118451] [PUBMED:16952352] [PUBMED:15314156] [PUBMED:19272169] [PUBMED:12802068] [PUBMED:17363898] [PUBMED:7513258] [PUBMED:1827664] [PUBMED:2541345] [PUBMED:8387483] [PUBMED:16620780] [PUBMED:11445578] [PUBMED:10734310] [PUBMED:16227611] [PUBMED:12941962] [PUBMED:15735664] [PUBMED:19071214] [PUBMED:7731718] [PUBMED:19289496] [PUBMED:11438654] [PUBMED:11896612] [PUBMED:11894096] [PUBMED:11896575] [PUBMED:7499247] [PUBMED:12147692] [PUBMED:11948414] [PUBMED:19881549] [PUBMED:19525225] [PUBMED:14684163] [PUBMED:17055484] [PUBMED:9668053] [PUBMED:10531383] [PUBMED:9681449] [PUBMED:1655405] [PUBMED:12686592] [PUBMED:19109251] [PUBMED:10679787] [PUBMED:9487126] [PUBMED:9886295] [PUBMED:12058075] [PUBMED:15452053] [PUBMED:9184210] [PUBMED:10871282] [PUBMED:17329361] [PUBMED:2554238]
Stabilization and expansion of the E-cadherin adherens junction [NCBI:137918] [Pathway Interaction Database:ecadherin_stabilization_pathway] [PUBMED:15057284] [PUBMED:10769210] [PUBMED:17261850] [PUBMED:18413140] [PUBMED:14704278] [PUBMED:19041755] [PUBMED:18690644] [PUBMED:16030252] [PUBMED:16537539] [PUBMED:19193766] [PUBMED:11381089] [PUBMED:16613855] [PUBMED:7962096] [PUBMED:17940061] [PUBMED:10511313] [PUBMED:8660958] [PUBMED:7790378] [PUBMED:18093941] [PUBMED:14709721] [PUBMED:17761530] [PUBMED:16371509] [PUBMED:11024053] [PUBMED:19158278] [PUBMED:9182672] [PUBMED:10085258] [PUBMED:10660044] [PUBMED:17646397] [PUBMED:10980705] [PUBMED:9566974] [PUBMED:11056534] [PUBMED:17664339] [PUBMED:17635938]
VEGFA-VEGFR2 Pathway [NCBI:1269483] [REACTOME:R-HSA-4420097] [PUBMED:17344076] [PUBMED:16633338] [PUBMED:19230644] [PUBMED:13678960]
VEGFR2 mediated vascular permeability [NCBI:1269484] [REACTOME:R-HSA-5218920] [PUBMED:17008595]