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Genes
IL12B
Gene - IL12B
full name
interleukin 12B
synonyms
CLMF, CLMF2, IL-12B, NKSF, NKSF2, IL12B, ENSG00000113302
HGNC
HGNC:5970
Entrez Gene
Gene:3593
ENSEMBL
ENSG00000113302
location
chr: 5
start: 158741791
stop: 158757481
strand: -
OMIM
OMIM:161561
: IL12B
OMIM:614890
: Immunodeficiency 29, mycobacteriosis
transcripts
NM_002187.2
pathways
African trypanosomiasis
[NCBI:194384]
[KEGG:hsa05143]
[PUBMED:9574925]
[PUBMED:12088284]
[PUBMED:19559585]
[PUBMED:20398209]
[PUBMED:17582444]
[PUBMED:19168735]
[PUBMED:19016378]
[PUBMED:11850009]
[PUBMED:16600243]
[PUBMED:19995590]
[PUBMED:19621073]
Allograft rejection
[NCBI:83123]
[KEGG:hsa05330]
[PUBMED:8835634]
[PUBMED:12023610]
[PUBMED:12563298]
[PUBMED:17445565]
[PUBMED:12216939]
[PUBMED:14710779]
[PUBMED:10746853]
[PUBMED:10571983]
[PUBMED:10331992]
[PUBMED:10667806]
Amoebiasis
[NCBI:167324]
[KEGG:hsa05146]
[PUBMED:9832261]
[PUBMED:16380324]
[PUBMED:14700586]
[PUBMED:18725798]
[PUBMED:12142490]
[PUBMED:10637584]
[PUBMED:20145703]
[PUBMED:11378035]
[PUBMED:12160867]
[PUBMED:15813717]
[PUBMED:19207103]
[PUBMED:12660071]
[PUBMED:20303955]
[PUBMED:11352795]
[PUBMED:14502002]
[PUBMED:10756002]
[PUBMED:17702556]
[PUBMED:17576362]
Chagas disease (American trypanosomiasis)
[NCBI:147809]
[KEGG:hsa05142]
[PUBMED:12377585]
[PUBMED:9794425]
[PUBMED:1717552]
[PUBMED:16238097]
[PUBMED:10066513]
[PUBMED:12874238]
[PUBMED:12036740]
[PUBMED:15917295]
[PUBMED:12055254]
[PUBMED:17651955]
[PUBMED:1396957]
[PUBMED:16175174]
[PUBMED:2194668]
[PUBMED:9190942]
[PUBMED:12377942]
[PUBMED:12427093]
[PUBMED:10234174]
[PUBMED:16030288]
[PUBMED:15223603]
[PUBMED:17110955]
Cytokine Signaling in Immune system
[NCBI:1269310]
[REACTOME:R-HSA-1280215]
[PUBMED:12613569]
Cytokine-cytokine receptor interaction
[NCBI:83051]
[KEGG:hsa04060]
[PUBMED:11071910]
[PUBMED:12072446]
[PUBMED:7791754]
[PUBMED:15032600]
[PUBMED:12651226]
[PUBMED:11252892]
[PUBMED:11796220]
[PUBMED:11312110]
[PUBMED:9862719]
[PUBMED:12421671]
[PUBMED:12039028]
[PUBMED:9759503]
[PUBMED:9395284]
[PUBMED:11166270]
[PUBMED:10714678]
[PUBMED:12651221]
Herpes simplex infection
[NCBI:377873]
[KEGG:hsa05168]
[PUBMED:12224518]
[PUBMED:17913820]
[PUBMED:12844494]
[PUBMED:10998601]
[PUBMED:15163721]
[PUBMED:19694546]
[PUBMED:16297150]
[PUBMED:14747533]
[PUBMED:12826401]
[PUBMED:14963113]
[PUBMED:15056211]
[PUBMED:12797447]
[PUBMED:21107701]
[PUBMED:10918307]
[PUBMED:10696424]
[PUBMED:16076403]
[PUBMED:10364308]
[PUBMED:17222692]
[PUBMED:9621021]
[PUBMED:12224508]
[PUBMED:19879619]
[PUBMED:11070032]
[PUBMED:9499021]
[PUBMED:18596690]
[PUBMED:12525427]
[PUBMED:12224517]
[PUBMED:10196275]
[PUBMED:15047834]
[PUBMED:18508584]
[PUBMED:20036979]
IL12-mediated signaling events
[NCBI:137922]
[Pathway Interaction Database:il12_2pathway]
[PUBMED:12874225]
[PUBMED:12221108]
[PUBMED:16380506]
[PUBMED:9768751]
[PUBMED:17114419]
[PUBMED:10358173]
[PUBMED:9890938]
[PUBMED:12213961]
[PUBMED:11120802]
[PUBMED:9202126]
[PUBMED:16641133]
[PUBMED:10198225]
[PUBMED:16763563]
[PUBMED:15728489]
[PUBMED:8103068]
[PUBMED:10903740]
[PUBMED:10201984]
[PUBMED:7638186]
[PUBMED:11894097]
[PUBMED:16220539]
[PUBMED:10961885]
[PUBMED:7594594]
[PUBMED:17110450]
[PUBMED:9582275]
[PUBMED:10320373]
[PUBMED:7528775]
[PUBMED:11207258]
[PUBMED:9038232]
[PUBMED:15522880]
[PUBMED:11175814]
[PUBMED:9531298]
[PUBMED:7722452]
[PUBMED:8943050]
[PUBMED:7553885]
[PUBMED:9454765]
IL23-mediated signaling events
[NCBI:138000]
[Pathway Interaction Database:il23pathway]
[PUBMED:16200068]
[PUBMED:12023338]
[PUBMED:17030949]
[PUBMED:16670770]
[PUBMED:17074928]
[PUBMED:15583831]
[PUBMED:16919486]
[PUBMED:12417590]
[PUBMED:16622035]
[PUBMED:16698929]
[PUBMED:14978083]
[PUBMED:12610626]
[PUBMED:15308705]
[PUBMED:16200070]
[PUBMED:15657292]
[PUBMED:16648837]
[PUBMED:11114383]
[PUBMED:12023369]
[PUBMED:9038232]
IL27-mediated signaling events
[NCBI:137929]
[Pathway Interaction Database:il27pathway]
[PUBMED:11672539]
[PUBMED:16365415]
[PUBMED:16906167]
[PUBMED:15356135]
[PUBMED:14657353]
[PUBMED:15944269]
[PUBMED:14764690]
[PUBMED:14614852]
[PUBMED:15308705]
[PUBMED:15004160]
[PUBMED:12734330]
[PUBMED:11057672]
[PUBMED:15494513]
[PUBMED:14614853]
[PUBMED:12121660]
[PUBMED:16906166]
[PUBMED:15749890]
Immune System
[NCBI:1269170]
[REACTOME:R-HSA-168256]
Inflammatory bowel disease (IBD)
[NCBI:842771]
[KEGG:hsa05321]
[PUBMED:17499605]
[PUBMED:12006974]
[PUBMED:18053739]
[PUBMED:20134493]
[PUBMED:10898785]
[PUBMED:18563156]
[PUBMED:23176791]
[PUBMED:18200661]
[PUBMED:12797537]
[PUBMED:21487504]
[PUBMED:19381306]
[PUBMED:21681604]
[PUBMED:19322214]
[PUBMED:16493424]
[PUBMED:18242222]
[PUBMED:12042806]
[PUBMED:9759857]
Influenza A
[NCBI:217173]
[KEGG:hsa05164]
[PUBMED:17267598]
[PUBMED:18049471]
[PUBMED:16882036]
[PUBMED:11907320]
[PUBMED:17944269]
[PUBMED:20629046]
[PUBMED:17072332]
[PUBMED:18588994]
[PUBMED:19864182]
[PUBMED:19290913]
[PUBMED:19420020]
[PUBMED:17213831]
[PUBMED:9060654]
[PUBMED:19481124]
[PUBMED:16494716]
[PUBMED:21147034]
[PUBMED:18980544]
[PUBMED:20020828]
[PUBMED:15502848]
[PUBMED:19782761]
Interleukin-10 signaling
[NCBI:1470924]
[REACTOME:R-HSA-6783783]
[PUBMED:11244051]
Interleukin-12 signaling
[NCBI:1383035]
[REACTOME:R-HSA-447115]
[PUBMED:1357073]
Interleukin-4 and 13 signaling
[NCBI:1470923]
[REACTOME:R-HSA-6785807]
[PUBMED:12704343]
[PUBMED:10358772]
Jak-STAT signaling pathway
[NCBI:83077]
[KEGG:hsa04630]
[PUBMED:21034406]
[PUBMED:22339650]
[PUBMED:16204702]
[PUBMED:25587654]
[PUBMED:24069565]
[PUBMED:22383755]
[PUBMED:24606160]
[PUBMED:10851053]
[PUBMED:23735217]
[PUBMED:25217450]
[PUBMED:21372217]
Legionellosis
[NCBI:469200]
[KEGG:hsa05134]
[PUBMED:19021631]
[PUBMED:19157961]
[PUBMED:20375353]
[PUBMED:19478083]
[PUBMED:18284575]
[PUBMED:19386084]
[PUBMED:19666608]
[PUBMED:15972519]
[PUBMED:18549456]
[PUBMED:1721820]
[PUBMED:17124169]
[PUBMED:19687203]
[PUBMED:18363881]
[PUBMED:19343209]
[PUBMED:20941588]
[PUBMED:16824952]
[PUBMED:18281405]
[PUBMED:18048909]
[PUBMED:16495539]
[PUBMED:12427954]
Leishmaniasis
[NCBI:144181]
[KEGG:hsa05140]
[PUBMED:11890722]
[PUBMED:7916951]
[PUBMED:10417174]
[PUBMED:11298294]
[PUBMED:10586030]
[PUBMED:15322192]
[PUBMED:15831826]
[PUBMED:11728310]
[PUBMED:15039466]
[PUBMED:10462516]
[PUBMED:10608501]
[PUBMED:15721837]
[PUBMED:15639739]
[PUBMED:14762510]
[PUBMED:18793215]
[PUBMED:7591091]
[PUBMED:12438359]
[PUBMED:18070909]
[PUBMED:17543969]
[PUBMED:15983048]
[PUBMED:16848789]
[PUBMED:10770277]
[PUBMED:9504340]
Measles
[NCBI:213306]
[KEGG:hsa05162]
[PUBMED:16237742]
[PUBMED:12804771]
[PUBMED:19198562]
[PUBMED:20376484]
[PUBMED:11385511]
[PUBMED:16963735]
[PUBMED:19198566]
[PUBMED:18922877]
[PUBMED:19203114]
[PUBMED:12620806]
[PUBMED:16690907]
[PUBMED:17720800]
[PUBMED:20636817]
[PUBMED:12410527]
[PUBMED:11582511]
[PUBMED:19203109]
[PUBMED:19203113]
[PUBMED:14585342]
[PUBMED:12805463]
Pertussis
[NCBI:218111]
[KEGG:hsa05133]
[PUBMED:20610650]
[PUBMED:12701623]
[PUBMED:15201703]
[PUBMED:18401006]
[PUBMED:20210554]
[PUBMED:16622221]
[PUBMED:17148436]
[PUBMED:21204863]
[PUBMED:20404851]
[PUBMED:10540218]
[PUBMED:16999837]
[PUBMED:16481212]
[PUBMED:16863919]
[PUBMED:16390441]
[PUBMED:21423776]
[PUBMED:17328678]
[PUBMED:12915094]
Proteoglycans in cancer
[NCBI:782000]
[KEGG:hsa05205]
[PUBMED:19433454]
[PUBMED:20655987]
[PUBMED:18798267]
[PUBMED:10633082]
[PUBMED:10687947]
[PUBMED:22735579]
[PUBMED:24412155]
[PUBMED:9346940]
[PUBMED:22087031]
[PUBMED:22194599]
[PUBMED:14711376]
[PUBMED:19255147]
[PUBMED:15655247]
[PUBMED:11717317]
[PUBMED:17971838]
[PUBMED:18413366]
[PUBMED:20974860]
[PUBMED:11830493]
[PUBMED:23058688]
[PUBMED:18450475]
[PUBMED:12748184]
[PUBMED:19733083]
[PUBMED:18812315]
[PUBMED:12509413]
[PUBMED:21155971]
[PUBMED:11931647]
[PUBMED:18949819]
[PUBMED:12729888]
[PUBMED:15994311]
[PUBMED:23305321]
[PUBMED:18505598]
[PUBMED:22563565]
[PUBMED:22033227]
RIG-I-like receptor signaling pathway
[NCBI:117292]
[KEGG:hsa04622]
[PUBMED:19224920]
[PUBMED:19076341]
[PUBMED:18549796]
[PUBMED:18591413]
[PUBMED:19615405]
[PUBMED:19120475]
[PUBMED:18439848]
[PUBMED:19120476]
[PUBMED:15208624]
[PUBMED:19539500]
[PUBMED:18272355]
[PUBMED:18984593]
Signaling by Interleukins
[NCBI:1269318]
[REACTOME:R-HSA-449147]
[PUBMED:19302047]
[PUBMED:12445398]
Th1 and Th2 cell differentiation
[NCBI:1458885]
[KEGG:hsa04658]
[PUBMED:15819694]
[PUBMED:12171942]
[PUBMED:19165228]
[PUBMED:23336087]
[PUBMED:26044597]
[PUBMED:19151746]
[PUBMED:19362457]
[PUBMED:22044277]
[PUBMED:11752608]
[PUBMED:23405903]
[PUBMED:19375293]
[PUBMED:24113868]
[PUBMED:19151747]
[PUBMED:23624818]
[PUBMED:22566933]
[PUBMED:11121747]
[PUBMED:20969597]
[PUBMED:20065998]
Toll-like receptor signaling pathway
[NCBI:83076]
[KEGG:hsa04620]
[PUBMED:16924467]
[PUBMED:17395581]
[PUBMED:17637696]
[PUBMED:12734364]
[PUBMED:17507094]
[PUBMED:14698224]
[PUBMED:11101877]
[PUBMED:16497588]
[PUBMED:14751764]
[PUBMED:17275323]
[PUBMED:17457343]
[PUBMED:16932750]
Toxoplasmosis
[NCBI:169642]
[KEGG:hsa05145]
[PUBMED:18617274]
[PUBMED:19400868]
[PUBMED:17024357]
[PUBMED:19744886]
[PUBMED:19891610]
[PUBMED:17110955]
[PUBMED:12106793]
[PUBMED:12580944]
[PUBMED:12857995]
[PUBMED:10234174]
[PUBMED:18327664]
[PUBMED:10525166]
[PUBMED:18059289]
[PUBMED:18775432]
[PUBMED:14642303]
[PUBMED:15361242]
[PUBMED:16339966]
[PUBMED:14987366]
[PUBMED:15639739]
Tuberculosis
[NCBI:213780]
[KEGG:hsa05152]
[PUBMED:20199890]
[PUBMED:21274449]
[PUBMED:17359235]
[PUBMED:20415982]
[PUBMED:18541216]
[PUBMED:19369951]
[PUBMED:15083155]
[PUBMED:11378475]
[PUBMED:15228522]
[PUBMED:19634703]
[PUBMED:21274433]
[PUBMED:19563525]
[PUBMED:18407066]
[PUBMED:18288961]
[PUBMED:16200082]
[PUBMED:17785780]
[PUBMED:11932234]
Type I diabetes mellitus
[NCBI:83095]
[KEGG:hsa04940]
[PUBMED:11507694]
[PUBMED:8072542]
[PUBMED:15889095]
[PUBMED:15889096]
[PUBMED:12796471]
[PUBMED:14617043]
[PUBMED:8786033]
[PUBMED:9719467]
[PUBMED:12752668]