full name
proprotein convertase subtilisin/kexin type 9

synonyms
FH3, HCHOLA3, LDLCQ1, NARC-1, NARC1, PC9, PCSK9, ENSG00000169174

HGNC
HGNC:20001

Entrez Gene
Gene:255738

ENSEMBL
ENSG00000169174

location
chr: 1
start: 55505149
stop: 55530526
strand: +

OMIM
OMIM:607786: PCSK9 (Autosomal dominant inheritance)
OMIM:603776: Hypercholesterolemia, familial, 3
OMIM:603776: {Low density lipoprotein cholesterol level QTL 1}

transcripts
NM_174936.3

pathways
LDL-mediated lipid transport [NCBI:1270008] [REACTOME:R-HSA-171052] [PUBMED:2088165] [PUBMED:15952897]
Lipid digestion, mobilization, and transport [NCBI:1270002] [REACTOME:R-HSA-73923]
Lipoprotein metabolism [NCBI:1270005] [REACTOME:R-HSA-174824]
Metabolism [NCBI:1269956] [REACTOME:R-HSA-1430728]
Metabolism of lipids and lipoproteins [NCBI:1270001] [REACTOME:R-HSA-556833]
VLDL interactions [NCBI:1427851] [REACTOME:R-HSA-8855121] [PUBMED:22461740] [PUBMED:12870663] [PUBMED:25544176] [PUBMED:20525064] [PUBMED:14748713] [PUBMED:22510808]
VLDLR internalisation and degradation [NCBI:1427853] [REACTOME:R-HSA-8866427] [PUBMED:18039658]