full name
proprotein convertase subtilisin/kexin type 9
synonyms
FH3, HCHOLA3, LDLCQ1, NARC-1, NARC1, PC9, PCSK9, ENSG00000169174
HGNC
HGNC:20001
Entrez Gene
Gene:255738
ENSEMBL
ENSG00000169174
location
chr: 1
start: 55505149
stop: 55530526
strand: +
OMIM
OMIM:607786:
PCSK9
(Autosomal dominant inheritance)
OMIM:603776:
Hypercholesterolemia, familial, 3
OMIM:603776:
{Low density lipoprotein cholesterol level QTL 1}
transcripts
NM_174936.3
pathways
LDL-mediated lipid transport
[NCBI:1270008]
[REACTOME:R-HSA-171052]
[PUBMED:2088165]
[PUBMED:15952897]
Lipid digestion, mobilization, and transport
[NCBI:1270002]
[REACTOME:R-HSA-73923]
Lipoprotein metabolism
[NCBI:1270005]
[REACTOME:R-HSA-174824]
Metabolism
[NCBI:1269956]
[REACTOME:R-HSA-1430728]
Metabolism of lipids and lipoproteins
[NCBI:1270001]
[REACTOME:R-HSA-556833]
VLDL interactions
[NCBI:1427851]
[REACTOME:R-HSA-8855121]
[PUBMED:22461740]
[PUBMED:12870663]
[PUBMED:25544176]
[PUBMED:20525064]
[PUBMED:14748713]
[PUBMED:22510808]
VLDLR internalisation and degradation
[NCBI:1427853]
[REACTOME:R-HSA-8866427]
[PUBMED:18039658]
