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Genes
HSPA1A
Gene - HSPA1A
full name
heat shock protein family A (Hsp70) member 1A
synonyms
HSP70-1, HSP70-1A, HSP70I, HSP72, HSPA1, HSPA1A, ENSG00000204389
HGNC
HGNC:5232
Entrez Gene
Gene:3303
ENSEMBL
ENSG00000204389
ENSG00000237724
ENSG00000235941
ENSG00000215328
ENSG00000234475
location
chr: 6
start: 31782952
stop: 31785719
strand: +
transcripts
NM_005345.5
pathways
AUF1 (hnRNP D0) binds and destabilizes mRNA
[NCBI:1269726]
[REACTOME:R-HSA-450408]
[PUBMED:16391004]
[PUBMED:12704645]
[PUBMED:10205060]
[PUBMED:12440953]
[PUBMED:18573886]
[PUBMED:12819195]
Antigen processing and presentation
[NCBI:83074]
[KEGG:hsa04612]
[PUBMED:12776207]
[PUBMED:15653315]
[PUBMED:15814328]
[PUBMED:20010787]
[PUBMED:15224094]
[PUBMED:15745856]
[PUBMED:11244040]
[PUBMED:15304636]
[PUBMED:11905820]
[PUBMED:16181333]
[PUBMED:16200082]
[PUBMED:15653312]
[PUBMED:15224093]
[PUBMED:15771591]
[PUBMED:12974477]
Attenuation phase
[NCBI:1270424]
[REACTOME:R-HSA-3371568]
[PUBMED:1936996]
Cellular response to heat stress
[NCBI:1270421]
[REACTOME:R-HSA-3371556]
[PUBMED:8455624]
[PUBMED:8441385]
Cellular responses to stress
[NCBI:1270414]
[REACTOME:R-HSA-2262752]
[PUBMED:15709958]
Disease
[NCBI:1268854]
[REACTOME:R-HSA-1643685]
Endocytosis
[NCBI:102279]
[KEGG:hsa04144]
[PUBMED:19696797]
[PUBMED:19007773]
[PUBMED:16203612]
[PUBMED:15687999]
[PUBMED:19924646]
[PUBMED:15261671]
[PUBMED:18647649]
[PUBMED:19325624]
[PUBMED:20110990]
[PUBMED:22193161]
Epstein-Barr virus infection
[NCBI:585562]
[KEGG:hsa05169]
[PUBMED:1658397]
[PUBMED:10683340]
[PUBMED:19375142]
[PUBMED:12438576]
[PUBMED:12910248]
[PUBMED:10400785]
[PUBMED:16007144]
[PUBMED:14576817]
[PUBMED:18559925]
[PUBMED:16352731]
[PUBMED:7895172]
[PUBMED:15510157]
[PUBMED:21518914]
[PUBMED:10891508]
[PUBMED:14673102]
[PUBMED:17159145]
[PUBMED:15542638]
[PUBMED:18786993]
[PUBMED:16603506]
[PUBMED:10644367]
[PUBMED:15021898]
[PUBMED:10666279]
[PUBMED:9565632]
Estrogen signaling pathway
[NCBI:799177]
[KEGG:hsa04915]
[PUBMED:15695368]
[PUBMED:16112267]
[PUBMED:9278514]
[PUBMED:19187465]
[PUBMED:12421825]
[PUBMED:12650715]
[PUBMED:18253054]
[PUBMED:16516516]
[PUBMED:14573532]
[PUBMED:18755790]
[PUBMED:18538919]
[PUBMED:19767412]
[PUBMED:14993035]
[PUBMED:19549587]
[PUBMED:15862823]
[PUBMED:20694192]
[PUBMED:19464786]
[PUBMED:21779010]
[PUBMED:16270355]
[PUBMED:21742056]
[PUBMED:19700741]
[PUBMED:21844907]
Export of Viral Ribonucleoproteins from Nucleus
[NCBI:1269121]
[REACTOME:R-HSA-168274]
[PUBMED:11118210]
[PUBMED:17081640]
[PUBMED:16806605]
Gene Expression
[NCBI:1269649]
[REACTOME:R-HSA-74160]
HSF1-dependent transactivation
[NCBI:1270423]
[REACTOME:R-HSA-3371571]
[PUBMED:7623826]
Immune System
[NCBI:1269170]
[REACTOME:R-HSA-168256]
Infectious disease
[NCBI:1269056]
[REACTOME:R-HSA-5663205]
Influenza A
[NCBI:217173]
[KEGG:hsa05164]
[PUBMED:17267598]
[PUBMED:18049471]
[PUBMED:16882036]
[PUBMED:11907320]
[PUBMED:17944269]
[PUBMED:20629046]
[PUBMED:17072332]
[PUBMED:18588994]
[PUBMED:19864182]
[PUBMED:19290913]
[PUBMED:19420020]
[PUBMED:17213831]
[PUBMED:9060654]
[PUBMED:19481124]
[PUBMED:16494716]
[PUBMED:21147034]
[PUBMED:18980544]
[PUBMED:20020828]
[PUBMED:15502848]
[PUBMED:19782761]
Influenza Infection
[NCBI:1269108]
[REACTOME:R-HSA-168254]
Influenza Life Cycle
[NCBI:1269109]
[REACTOME:R-HSA-168255]
Innate Immune System
[NCBI:1269203]
[REACTOME:R-HSA-168249]
Legionellosis
[NCBI:469200]
[KEGG:hsa05134]
[PUBMED:19021631]
[PUBMED:19157961]
[PUBMED:20375353]
[PUBMED:19478083]
[PUBMED:18284575]
[PUBMED:19386084]
[PUBMED:19666608]
[PUBMED:15972519]
[PUBMED:18549456]
[PUBMED:1721820]
[PUBMED:17124169]
[PUBMED:19687203]
[PUBMED:18363881]
[PUBMED:19343209]
[PUBMED:20941588]
[PUBMED:16824952]
[PUBMED:18281405]
[PUBMED:18048909]
[PUBMED:16495539]
[PUBMED:12427954]
Longevity regulating pathway - multiple species
[NCBI:1340713]
[KEGG:hsa04213]
[PUBMED:26682004]
[PUBMED:20098959]
[PUBMED:17684529]
[PUBMED:14534077]
[PUBMED:16304601]
[PUBMED:17701476]
[PUBMED:20395504]
[PUBMED:18373439]
[PUBMED:20336132]
[PUBMED:21909281]
[PUBMED:26525455]
[PUBMED:22094419]
[PUBMED:12610293]
[PUBMED:15768047]
[PUBMED:23615258]
[PUBMED:18946478]
[PUBMED:20097433]
[PUBMED:21841070]
[PUBMED:25153840]
MAPK signaling pathway
[NCBI:83048]
[KEGG:hsa04010]
[PUBMED:11749383]
[PUBMED:12566928]
[PUBMED:12849693]
[PUBMED:12676795]
[PUBMED:12947395]
[PUBMED:14597384]
[PUBMED:11369511]
[PUBMED:12191611]
[PUBMED:12390245]
Measles
[NCBI:213306]
[KEGG:hsa05162]
[PUBMED:16237742]
[PUBMED:12804771]
[PUBMED:19198562]
[PUBMED:20376484]
[PUBMED:11385511]
[PUBMED:16963735]
[PUBMED:19198566]
[PUBMED:18922877]
[PUBMED:19203114]
[PUBMED:12620806]
[PUBMED:16690907]
[PUBMED:17720800]
[PUBMED:20636817]
[PUBMED:12410527]
[PUBMED:11582511]
[PUBMED:19203109]
[PUBMED:19203113]
[PUBMED:14585342]
[PUBMED:12805463]
Neutrophil degranulation
[NCBI:1457780]
[REACTOME:R-HSA-6798695]
[PUBMED:20338884]
[PUBMED:1378856]
[PUBMED:17627888]
[PUBMED:23650620]
[PUBMED:8692836]
Prion diseases
[NCBI:101144]
[KEGG:hsa05020]
[PUBMED:15695097]
[PUBMED:18558863]
[PUBMED:11592845]
[PUBMED:15528202]
[PUBMED:17051207]
[PUBMED:18245809]
[PUBMED:14705136]
[PUBMED:10398674]
[PUBMED:15890824]
[PUBMED:14661267]
[PUBMED:15611724]
[PUBMED:15342004]
[PUBMED:18391177]
[PUBMED:17085779]
[PUBMED:12850426]
Protein processing in endoplasmic reticulum
[NCBI:167325]
[KEGG:hsa04141]
[PUBMED:20347046]
[PUBMED:18023214]
[PUBMED:20219571]
[PUBMED:19491040]
[PUBMED:20112977]
Regulation of HSF1-mediated heat shock response
[NCBI:1270425]
[REACTOME:R-HSA-3371453]
[PUBMED:7623826]
Regulation of mRNA stability by proteins that bind AU-rich elements
[NCBI:1269725]
[REACTOME:R-HSA-450531]
[PUBMED:12440953]
[PUBMED:12704645]
[PUBMED:15460540]
[PUBMED:16391004]
Spliceosome
[NCBI:125136]
[KEGG:hsa03040]
[PUBMED:10978320]
[PUBMED:19239890]
[PUBMED:19733268]
[PUBMED:17537823]
Toxoplasmosis
[NCBI:169642]
[KEGG:hsa05145]
[PUBMED:18617274]
[PUBMED:19400868]
[PUBMED:17024357]
[PUBMED:19744886]
[PUBMED:19891610]
[PUBMED:17110955]
[PUBMED:12106793]
[PUBMED:12580944]
[PUBMED:12857995]
[PUBMED:10234174]
[PUBMED:18327664]
[PUBMED:10525166]
[PUBMED:18059289]
[PUBMED:18775432]
[PUBMED:14642303]
[PUBMED:15361242]
[PUBMED:16339966]
[PUBMED:14987366]
[PUBMED:15639739]
Viral RNP Complexes in the Host Cell Nucleus
[NCBI:1269122]
[REACTOME:R-HSA-168330]
[PUBMED:11531417]