Logo
full name
heat shock protein family A (Hsp70) member 1A

synonyms
HSP70-1, HSP70-1A, HSP70I, HSP72, HSPA1, HSPA1A, ENSG00000204389

HGNC
HGNC:5232

Entrez Gene
Gene:3303

ENSEMBL
ENSG00000204389
ENSG00000237724
ENSG00000235941
ENSG00000215328
ENSG00000234475

location
chr: 6
start: 31782952
stop: 31785719
strand: +

transcripts
NM_005345.5

pathways
AUF1 (hnRNP D0) binds and destabilizes mRNA [NCBI:1269726] [REACTOME:R-HSA-450408] [PUBMED:16391004] [PUBMED:12704645] [PUBMED:10205060] [PUBMED:12440953] [PUBMED:18573886] [PUBMED:12819195]
Antigen processing and presentation [NCBI:83074] [KEGG:hsa04612] [PUBMED:12776207] [PUBMED:15653315] [PUBMED:15814328] [PUBMED:20010787] [PUBMED:15224094] [PUBMED:15745856] [PUBMED:11244040] [PUBMED:15304636] [PUBMED:11905820] [PUBMED:16181333] [PUBMED:16200082] [PUBMED:15653312] [PUBMED:15224093] [PUBMED:15771591] [PUBMED:12974477]
Attenuation phase [NCBI:1270424] [REACTOME:R-HSA-3371568] [PUBMED:1936996]
Cellular response to heat stress [NCBI:1270421] [REACTOME:R-HSA-3371556] [PUBMED:8455624] [PUBMED:8441385]
Cellular responses to stress [NCBI:1270414] [REACTOME:R-HSA-2262752] [PUBMED:15709958]
Disease [NCBI:1268854] [REACTOME:R-HSA-1643685]
Endocytosis [NCBI:102279] [KEGG:hsa04144] [PUBMED:19696797] [PUBMED:19007773] [PUBMED:16203612] [PUBMED:15687999] [PUBMED:19924646] [PUBMED:15261671] [PUBMED:18647649] [PUBMED:19325624] [PUBMED:20110990] [PUBMED:22193161]
Epstein-Barr virus infection [NCBI:585562] [KEGG:hsa05169] [PUBMED:1658397] [PUBMED:10683340] [PUBMED:19375142] [PUBMED:12438576] [PUBMED:12910248] [PUBMED:10400785] [PUBMED:16007144] [PUBMED:14576817] [PUBMED:18559925] [PUBMED:16352731] [PUBMED:7895172] [PUBMED:15510157] [PUBMED:21518914] [PUBMED:10891508] [PUBMED:14673102] [PUBMED:17159145] [PUBMED:15542638] [PUBMED:18786993] [PUBMED:16603506] [PUBMED:10644367] [PUBMED:15021898] [PUBMED:10666279] [PUBMED:9565632]
Estrogen signaling pathway [NCBI:799177] [KEGG:hsa04915] [PUBMED:15695368] [PUBMED:16112267] [PUBMED:9278514] [PUBMED:19187465] [PUBMED:12421825] [PUBMED:12650715] [PUBMED:18253054] [PUBMED:16516516] [PUBMED:14573532] [PUBMED:18755790] [PUBMED:18538919] [PUBMED:19767412] [PUBMED:14993035] [PUBMED:19549587] [PUBMED:15862823] [PUBMED:20694192] [PUBMED:19464786] [PUBMED:21779010] [PUBMED:16270355] [PUBMED:21742056] [PUBMED:19700741] [PUBMED:21844907]
Export of Viral Ribonucleoproteins from Nucleus [NCBI:1269121] [REACTOME:R-HSA-168274] [PUBMED:11118210] [PUBMED:17081640] [PUBMED:16806605]
Gene Expression [NCBI:1269649] [REACTOME:R-HSA-74160]
HSF1-dependent transactivation [NCBI:1270423] [REACTOME:R-HSA-3371571] [PUBMED:7623826]
Immune System [NCBI:1269170] [REACTOME:R-HSA-168256]
Infectious disease [NCBI:1269056] [REACTOME:R-HSA-5663205]
Influenza A [NCBI:217173] [KEGG:hsa05164] [PUBMED:17267598] [PUBMED:18049471] [PUBMED:16882036] [PUBMED:11907320] [PUBMED:17944269] [PUBMED:20629046] [PUBMED:17072332] [PUBMED:18588994] [PUBMED:19864182] [PUBMED:19290913] [PUBMED:19420020] [PUBMED:17213831] [PUBMED:9060654] [PUBMED:19481124] [PUBMED:16494716] [PUBMED:21147034] [PUBMED:18980544] [PUBMED:20020828] [PUBMED:15502848] [PUBMED:19782761]
Influenza Infection [NCBI:1269108] [REACTOME:R-HSA-168254]
Influenza Life Cycle [NCBI:1269109] [REACTOME:R-HSA-168255]
Innate Immune System [NCBI:1269203] [REACTOME:R-HSA-168249]
Legionellosis [NCBI:469200] [KEGG:hsa05134] [PUBMED:19021631] [PUBMED:19157961] [PUBMED:20375353] [PUBMED:19478083] [PUBMED:18284575] [PUBMED:19386084] [PUBMED:19666608] [PUBMED:15972519] [PUBMED:18549456] [PUBMED:1721820] [PUBMED:17124169] [PUBMED:19687203] [PUBMED:18363881] [PUBMED:19343209] [PUBMED:20941588] [PUBMED:16824952] [PUBMED:18281405] [PUBMED:18048909] [PUBMED:16495539] [PUBMED:12427954]
Longevity regulating pathway - multiple species [NCBI:1340713] [KEGG:hsa04213] [PUBMED:26682004] [PUBMED:20098959] [PUBMED:17684529] [PUBMED:14534077] [PUBMED:16304601] [PUBMED:17701476] [PUBMED:20395504] [PUBMED:18373439] [PUBMED:20336132] [PUBMED:21909281] [PUBMED:26525455] [PUBMED:22094419] [PUBMED:12610293] [PUBMED:15768047] [PUBMED:23615258] [PUBMED:18946478] [PUBMED:20097433] [PUBMED:21841070] [PUBMED:25153840]
MAPK signaling pathway [NCBI:83048] [KEGG:hsa04010] [PUBMED:11749383] [PUBMED:12566928] [PUBMED:12849693] [PUBMED:12676795] [PUBMED:12947395] [PUBMED:14597384] [PUBMED:11369511] [PUBMED:12191611] [PUBMED:12390245]
Measles [NCBI:213306] [KEGG:hsa05162] [PUBMED:16237742] [PUBMED:12804771] [PUBMED:19198562] [PUBMED:20376484] [PUBMED:11385511] [PUBMED:16963735] [PUBMED:19198566] [PUBMED:18922877] [PUBMED:19203114] [PUBMED:12620806] [PUBMED:16690907] [PUBMED:17720800] [PUBMED:20636817] [PUBMED:12410527] [PUBMED:11582511] [PUBMED:19203109] [PUBMED:19203113] [PUBMED:14585342] [PUBMED:12805463]
Neutrophil degranulation [NCBI:1457780] [REACTOME:R-HSA-6798695] [PUBMED:20338884] [PUBMED:1378856] [PUBMED:17627888] [PUBMED:23650620] [PUBMED:8692836]
Prion diseases [NCBI:101144] [KEGG:hsa05020] [PUBMED:15695097] [PUBMED:18558863] [PUBMED:11592845] [PUBMED:15528202] [PUBMED:17051207] [PUBMED:18245809] [PUBMED:14705136] [PUBMED:10398674] [PUBMED:15890824] [PUBMED:14661267] [PUBMED:15611724] [PUBMED:15342004] [PUBMED:18391177] [PUBMED:17085779] [PUBMED:12850426]
Protein processing in endoplasmic reticulum [NCBI:167325] [KEGG:hsa04141] [PUBMED:20347046] [PUBMED:18023214] [PUBMED:20219571] [PUBMED:19491040] [PUBMED:20112977]
Regulation of HSF1-mediated heat shock response [NCBI:1270425] [REACTOME:R-HSA-3371453] [PUBMED:7623826]
Regulation of mRNA stability by proteins that bind AU-rich elements [NCBI:1269725] [REACTOME:R-HSA-450531] [PUBMED:12440953] [PUBMED:12704645] [PUBMED:15460540] [PUBMED:16391004]
Spliceosome [NCBI:125136] [KEGG:hsa03040] [PUBMED:10978320] [PUBMED:19239890] [PUBMED:19733268] [PUBMED:17537823]
Toxoplasmosis [NCBI:169642] [KEGG:hsa05145] [PUBMED:18617274] [PUBMED:19400868] [PUBMED:17024357] [PUBMED:19744886] [PUBMED:19891610] [PUBMED:17110955] [PUBMED:12106793] [PUBMED:12580944] [PUBMED:12857995] [PUBMED:10234174] [PUBMED:18327664] [PUBMED:10525166] [PUBMED:18059289] [PUBMED:18775432] [PUBMED:14642303] [PUBMED:15361242] [PUBMED:16339966] [PUBMED:14987366] [PUBMED:15639739]
Viral RNP Complexes in the Host Cell Nucleus [NCBI:1269122] [REACTOME:R-HSA-168330] [PUBMED:11531417]