Logo
full name
triggering receptor expressed on myeloid cells 2

synonyms
TREM-2, Trem2a, Trem2b, Trem2c, TREM2, ENSG00000095970

HGNC
HGNC:17761

Entrez Gene
Gene:54209

ENSEMBL
ENSG00000095970

location
chr: 6
start: 41126244
stop: 41130924
strand: -

OMIM
OMIM:605086: TREM2
OMIM:618193: Polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy 2

transcripts
NM_001271821.1
NM_018965.3

pathways
Adaptive Immune System [NCBI:1269171] [REACTOME:R-HSA-1280218] [PUBMED:16551257] [PUBMED:21682741] [PUBMED:11861602]
Axon guidance [NCBI:83065] [KEGG:hsa04360] [NCBI:1270303] [REACTOME:R-HSA-422475] [PUBMED:14682358] [PUBMED:15084255] [PUBMED:11687826] [PUBMED:15818466] [PUBMED:15363605] [PUBMED:12471249] [PUBMED:15630019] [PUBMED:11891122] [PUBMED:15960985] [PUBMED:12677003]
DAP12 interactions [NCBI:1269283] [REACTOME:R-HSA-2172127] [PUBMED:19120482] [PUBMED:17220916] [PUBMED:9490415] [PUBMED:18192027] [PUBMED:15884055]
DAP12 signaling [NCBI:1269284] [REACTOME:R-HSA-2424491] [PUBMED:15884055] [PUBMED:17110943] [PUBMED:17220916]
Developmental Biology [NCBI:1270302] [REACTOME:R-HSA-1266738]
Immune System [NCBI:1269170] [REACTOME:R-HSA-168256]
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell [NCBI:1269201] [REACTOME:R-HSA-198933] [PUBMED:17218381] [PUBMED:16603343] [PUBMED:16616474] [PUBMED:11244041] [PUBMED:16132082] [PUBMED:18425107]
Innate Immune System [NCBI:1269203] [REACTOME:R-HSA-168249]
Osteoclast differentiation [NCBI:193147] [KEGG:hsa04380] [PUBMED:17633024] [PUBMED:18382763] [PUBMED:18329366] [PUBMED:17869613] [PUBMED:18722561] [PUBMED:15122243] [PUBMED:20703218] [PUBMED:12748652] [PUBMED:12110142] [PUBMED:19585227] [PUBMED:15546140] [PUBMED:16184196] [PUBMED:15817678] [PUBMED:20392226] [PUBMED:16313349] [PUBMED:16313342] [PUBMED:17380158] [PUBMED:18451259]
Other semaphorin interactions [NCBI:1270311] [REACTOME:R-HSA-416700]
Semaphorin interactions [NCBI:1270304] [REACTOME:R-HSA-373755] [PUBMED:12593985] [PUBMED:12471249] [PUBMED:18269210] [PUBMED:16939971] [PUBMED:18374575]