full name
protein phosphatase 2 regulatory subunit B'delta

synonyms
B56D, PPP2R5D, ENSG00000112640

HGNC
HGNC:9312

Entrez Gene
Gene:5528

ENSEMBL
ENSG00000112640

location
chr: 6
start: 42952218
stop: 42980083
strand: +

OMIM
OMIM:601646: PPP2R5D
OMIM:616355: Mental retardation, autosomal dominant 35

transcripts
NM_001270476.1
NM_006245.3
NM_180976.2
NM_180977.2

pathways
AMER1 mutants destabilize the destruction complex [NCBI:1268913] [REACTOME:R-HSA-4839748] [PUBMED:17510365] [PUBMED:21248786] [PUBMED:23256519]
AMPK signaling pathway [NCBI:989139] [KEGG:hsa04152] [PUBMED:22885100] [PUBMED:18725075] [PUBMED:22700795] [PUBMED:19724019] [PUBMED:19584320] [PUBMED:16644802] [PUBMED:20010958] [PUBMED:16479585] [PUBMED:19197243] [PUBMED:23565491] [PUBMED:20357764] [PUBMED:16723978] [PUBMED:16054041] [PUBMED:19393004] [PUBMED:23899560] [PUBMED:17307971] [PUBMED:15509864] [PUBMED:23024365] [PUBMED:23747347] [PUBMED:19629071]
APC truncation mutants have impaired AXIN binding [NCBI:1268909] [REACTOME:R-HSA-5467337] [PUBMED:10921899] [PUBMED:1338904] [PUBMED:11057903] [PUBMED:10213492] [PUBMED:8111410]
ARMS-mediated activation [NCBI:1269471] [REACTOME:R-HSA-170984] [PUBMED:9069267]
AXIN missense mutants destabilize the destruction complex [NCBI:1268912] [REACTOME:R-HSA-5467340] [PUBMED:12101426] [PUBMED:10862053] [PUBMED:11746989] [PUBMED:10700176]
AXIN mutants destabilize the destruction complex, activating WNT signaling [NCBI:1268910] [REACTOME:R-HSA-4839735] [PUBMED:15735151] [PUBMED:23256519] [PUBMED:12101426] [PUBMED:11746989] [PUBMED:10700176] [PUBMED:11585731]
Activated TLR4 signalling [NCBI:1269236] [REACTOME:R-HSA-166054] [PUBMED:15276183] [PUBMED:15588429] [PUBMED:15845500] [PUBMED:15596121]
Adaptive Immune System [NCBI:1269171] [REACTOME:R-HSA-1280218] [PUBMED:16551257] [PUBMED:21682741] [PUBMED:11861602]
Adrenergic signaling in cardiomyocytes [NCBI:908257] [KEGG:hsa04261] [PUBMED:15232578] [PUBMED:20923637] [PUBMED:10571541] [PUBMED:11604549] [PUBMED:17988210] [PUBMED:11805843] [PUBMED:15142747] [PUBMED:21212391] [PUBMED:20658186] [PUBMED:16765984] [PUBMED:19874988] [PUBMED:19883653] [PUBMED:15979723] [PUBMED:18407781] [PUBMED:22022314] [PUBMED:12439640] [PUBMED:17826821] [PUBMED:15765137]
Alpha-synuclein signaling [NCBI:137913] [Pathway Interaction Database:alphasynuclein_pathway] [PUBMED:12551928] [PUBMED:15671022] [PUBMED:12887682] [PUBMED:14991825] [PUBMED:11431533] [PUBMED:11588587] [PUBMED:16030137] [PUBMED:15845543] [PUBMED:11590439] [PUBMED:12096713] [PUBMED:11687285] [PUBMED:15978696] [PUBMED:10407019] [PUBMED:11078745] [PUBMED:16403519] [PUBMED:14985429] [PUBMED:14645218] [PUBMED:12787066] [PUBMED:11292651] [PUBMED:12421356] [PUBMED:15944382] [PUBMED:10567343] [PUBMED:11744621] [PUBMED:15935068] [PUBMED:12928483] [PUBMED:11821392] [PUBMED:10852916]
Aurora A signaling [NCBI:137925] [Pathway Interaction Database:aurora_a_pathway] [PUBMED:17308110] [PUBMED:16894566] [PUBMED:16631581] [PUBMED:17229885] [PUBMED:15128871] [PUBMED:14990569] [PUBMED:12177045] [PUBMED:14580337] [PUBMED:14724178] [PUBMED:17545617] [PUBMED:15687499] [PUBMED:11163242] [PUBMED:14603251] [PUBMED:17060449] [PUBMED:12208850] [PUBMED:12815066] [PUBMED:17125467] [PUBMED:13678582] [PUBMED:15987997] [PUBMED:15966895] [PUBMED:11976319] [PUBMED:14702041] [PUBMED:16246726] [PUBMED:17452972] [PUBMED:12082625] [PUBMED:11039908] [PUBMED:14667408] [PUBMED:12577065] [PUBMED:14600264] [PUBMED:11756469] [PUBMED:16772293] [PUBMED:12023018] [PUBMED:15469940] [PUBMED:16082213]
Aurora B signaling [NCBI:138080] [Pathway Interaction Database:aurora_b_pathway] [PUBMED:14960279] [PUBMED:15249581] [PUBMED:17129783] [PUBMED:15263015] [PUBMED:15854913] [PUBMED:14605209] [PUBMED:12689593] [PUBMED:15499654] [PUBMED:17483322] [PUBMED:15316025] [PUBMED:11350965] [PUBMED:11516652] [PUBMED:11976319] [PUBMED:16222246] [PUBMED:12925766] [PUBMED:15260989] [PUBMED:16764853] [PUBMED:15796717] [PUBMED:16916643] [PUBMED:14667408] [PUBMED:17389228] [PUBMED:16687578] [PUBMED:14722118] [PUBMED:12082625] [PUBMED:17356064] [PUBMED:16222244] [PUBMED:11756469] [PUBMED:17457057] [PUBMED:15350530] [PUBMED:17322402] [PUBMED:11856369] [PUBMED:17199039] [PUBMED:17129782] [PUBMED:12419797] [PUBMED:16046481] [PUBMED:15064709] [PUBMED:12458200] [PUBMED:15064354] [PUBMED:14674694] [PUBMED:16179162] [PUBMED:17543862] [PUBMED:17215513] [PUBMED:12686604] [PUBMED:16537398]
Axon guidance [NCBI:83065] [KEGG:hsa04360] [NCBI:1270303] [REACTOME:R-HSA-422475] [PUBMED:14682358] [PUBMED:15084255] [PUBMED:11687826] [PUBMED:15818466] [PUBMED:15363605] [PUBMED:12471249] [PUBMED:15630019] [PUBMED:11891122] [PUBMED:15960985] [PUBMED:12677003]
Beta-catenin phosphorylation cascade [NCBI:1269597] [REACTOME:R-HSA-196299] [PUBMED:11955436] [PUBMED:12000790]
CTLA4 inhibitory signaling [NCBI:1269181] [REACTOME:R-HSA-389513] [PUBMED:11905831] [PUBMED:10374692] [PUBMED:16551244] [PUBMED:12876557]
Cell Cycle [NCBI:1269741] [REACTOME:R-HSA-1640170]
Cell Cycle, Mitotic [NCBI:1269763] [REACTOME:R-HSA-69278]
Costimulation by the CD28 family [NCBI:1269177] [REACTOME:R-HSA-388841] [PUBMED:10374692] [PUBMED:14647476] [PUBMED:11905831]
Cytokine Signaling in Immune system [NCBI:1269310] [REACTOME:R-HSA-1280215] [PUBMED:12613569]
DAP12 interactions [NCBI:1269283] [REACTOME:R-HSA-2172127] [PUBMED:19120482] [PUBMED:17220916] [PUBMED:9490415] [PUBMED:18192027] [PUBMED:15884055]
DAP12 signaling [NCBI:1269284] [REACTOME:R-HSA-2424491] [PUBMED:15884055] [PUBMED:17110943] [PUBMED:17220916]
DARPP-32 events [NCBI:1269591] [REACTOME:R-HSA-180024] [PUBMED:14744247] [PUBMED:2908293]
Degradation of beta-catenin by the destruction complex [NCBI:1269596] [REACTOME:R-HSA-195253] [PUBMED:17143292]
Developmental Biology [NCBI:1270302] [REACTOME:R-HSA-1266738]
Disassembly of the destruction complex and recruitment of AXIN to the membrane [NCBI:1269601] [REACTOME:R-HSA-4641262] [PUBMED:10647780] [PUBMED:10581160] [PUBMED:14551908] [PUBMED:15084453] [PUBMED:19619488] [PUBMED:19759537] [PUBMED:14731402] [PUBMED:18234723] [PUBMED:15459103] [PUBMED:22363759] [PUBMED:17318175] [PUBMED:11336703] [PUBMED:16341017] [PUBMED:10421629] [PUBMED:17569865]
Disease [NCBI:1268854] [REACTOME:R-HSA-1643685]
Diseases of signal transduction [NCBI:1268855] [REACTOME:R-HSA-5663202] [PUBMED:12509752]
Dopaminergic synapse [NCBI:469199] [KEGG:hsa04728] [PUBMED:20727368] [PUBMED:10433257] [PUBMED:17408758] [PUBMED:15292232] [PUBMED:9457173] [PUBMED:17349698] [PUBMED:15521361] [PUBMED:18353279] [PUBMED:21303898] [PUBMED:19251795] [PUBMED:15381316] [PUBMED:15590733] [PUBMED:20224735] [PUBMED:19138563] [PUBMED:12967774]
Downstream signal transduction [NCBI:1269479] [REACTOME:R-HSA-186763] [PUBMED:10508235] [PUBMED:9739761]
Downstream signaling events of B Cell Receptor (BCR) [NCBI:1269185] [REACTOME:R-HSA-1168372] [PUBMED:17052215] [PUBMED:19909372]
ERK/MAPK targets [NCBI:1269215] [REACTOME:R-HSA-198753]
ERKs are inactivated [NCBI:1269216] [REACTOME:R-HSA-202670] [PUBMED:17322878] [PUBMED:15115656]
FCERI mediated MAPK activation [NCBI:1269299] [REACTOME:R-HSA-2871796] [PUBMED:19290926] [PUBMED:19909365] [PUBMED:17122878]
Fc epsilon receptor (FCERI) signaling [NCBI:1269298] [REACTOME:R-HSA-2454202] [PUBMED:15099567] [PUBMED:21799019]
Frs2-mediated activation [NCBI:1269470] [REACTOME:R-HSA-170968] [PUBMED:9069267]
GAB1 signalosome [NCBI:1269384] [REACTOME:R-HSA-180292] [PUBMED:15550174]
GRB2 events in EGFR signaling [NCBI:1269382] [REACTOME:R-HSA-179812] [PUBMED:11706405] [PUBMED:11498013]
Gastrin-CREB signalling pathway via PKC and MAPK [NCBI:1269592] [REACTOME:R-HSA-881907] [PUBMED:10413847] [PUBMED:7491953] [PUBMED:17698287]
Glucose metabolism [NCBI:1269959] [REACTOME:R-HSA-70326]
Glycolysis [NCBI:1269960] [REACTOME:R-HSA-70171] [PUBMED:16051738]
Hemostasis [NCBI:1269340] [REACTOME:R-HSA-109582]
IGF1R signaling cascade [NCBI:1269618] [REACTOME:R-HSA-2428924] [PUBMED:17598937] [PUBMED:20975071] [PUBMED:22649417] [PUBMED:21042815] [PUBMED:18927274] [PUBMED:20098959]
IL2-mediated signaling events [NCBI:137976] [Pathway Interaction Database:il2_1pathway] [PUBMED:7568005] [PUBMED:10962026] [PUBMED:1545122] [PUBMED:10602027] [PUBMED:15170389] [PUBMED:9092570] [PUBMED:7509794] [PUBMED:15356145] [PUBMED:9973481] [PUBMED:10899310] [PUBMED:9195132] [PUBMED:7544001] [PUBMED:7777534] [PUBMED:12681450] [PUBMED:7665592] [PUBMED:8702919] [PUBMED:1708096] [PUBMED:8643566] [PUBMED:7988557] [PUBMED:7737351] [PUBMED:1532814] [PUBMED:8262551] [PUBMED:8025955] [PUBMED:10993906] [PUBMED:3095922] [PUBMED:8805624] [PUBMED:9391116] [PUBMED:7973658] [PUBMED:11331873] [PUBMED:10421845] [PUBMED:8119884] [PUBMED:7781605] [PUBMED:12543077] [PUBMED:9133424] [PUBMED:1618313] [PUBMED:1940342] [PUBMED:9382798] [PUBMED:10514520] [PUBMED:7973659] [PUBMED:1639773] [PUBMED:9029085] [PUBMED:7760801] [PUBMED:1460037] [PUBMED:9202126] [PUBMED:1652056] [PUBMED:12393431] [PUBMED:8397196] [PUBMED:2047859] [PUBMED:7688728] [PUBMED:8700888] [PUBMED:7528668] [PUBMED:9305919] [PUBMED:2303462] [PUBMED:7568001] [PUBMED:9822600] [PUBMED:7543676] [PUBMED:7499365] [PUBMED:10843677] [PUBMED:7600304] [PUBMED:7719937] [PUBMED:9590209] [PUBMED:9794391] [PUBMED:10849428] [PUBMED:8294403] [PUBMED:10373548] [PUBMED:2590941] [PUBMED:9512511] [PUBMED:6434688] [PUBMED:9697832] [PUBMED:10982827] [PUBMED:10214954] [PUBMED:10825200] [PUBMED:1535827] [PUBMED:10369681] [PUBMED:7719938] [PUBMED:1655887] [PUBMED:8376945] [PUBMED:1996324] [PUBMED:7479881] [PUBMED:10962581] [PUBMED:7973657] [PUBMED:1631559] [PUBMED:10066828] [PUBMED:9169478] [PUBMED:8552611] [PUBMED:8483935] [PUBMED:2106566] [PUBMED:16199887]
IRS-mediated signalling [NCBI:1269431] [REACTOME:R-HSA-112399]
IRS-related events triggered by IGF1R [NCBI:1269620] [REACTOME:R-HSA-2428928] [PUBMED:17598937] [PUBMED:20975071] [PUBMED:22649417] [PUBMED:18927274] [PUBMED:21042815] [PUBMED:20098959]
Immune System [NCBI:1269170] [REACTOME:R-HSA-168256]
Innate Immune System [NCBI:1269203] [REACTOME:R-HSA-168249]
Insulin receptor signalling cascade [NCBI:1269429] [REACTOME:R-HSA-74751] [PUBMED:9677303] [PUBMED:11282018]
Integration of energy metabolism [NCBI:1270101] [REACTOME:R-HSA-163685] [PUBMED:15509864] [PUBMED:12721358] [PUBMED:12626323]
Interleukin receptor SHC signaling [NCBI:1269322] [REACTOME:R-HSA-912526] [PUBMED:8294403]
Interleukin-2 signaling [NCBI:1269321] [REACTOME:R-HSA-451927] [PUBMED:17936914] [PUBMED:18817510] [PUBMED:19543225] [PUBMED:18062768]
Interleukin-3, 5 and GM-CSF signaling [NCBI:1269323] [REACTOME:R-HSA-512988] [PUBMED:10450743] [PUBMED:9766809]
Lissencephaly gene (LIS1) in neuronal migration and development [NCBI:137984] [Pathway Interaction Database:lis1pathway] [PUBMED:16203747] [PUBMED:16369480] [PUBMED:16138011] [PUBMED:8090221] [PUBMED:14578885] [PUBMED:11940666] [PUBMED:7690334] [PUBMED:10491172] [PUBMED:15762842] [PUBMED:11734602] [PUBMED:11889140] [PUBMED:12796778] [PUBMED:14507966] [PUBMED:11163260] [PUBMED:14724251] [PUBMED:12911752] [PUBMED:10896159]
M Phase [NCBI:1269810] [REACTOME:R-HSA-68886]
MAP kinase activation in TLR cascade [NCBI:1269211] [REACTOME:R-HSA-450294] [PUBMED:17637696] [PUBMED:11861597] [PUBMED:19196711] [PUBMED:11242034]
MAPK family signaling cascades [NCBI:1269501] [REACTOME:R-HSA-5683057] [PUBMED:21167873] [PUBMED:17161475] [PUBMED:22535895] [PUBMED:21372320]
MAPK targets/ Nuclear events mediated by MAP kinases [NCBI:1269214] [REACTOME:R-HSA-450282] [PUBMED:17158707] [PUBMED:16393692] [PUBMED:12471242]
MAPK1/MAPK3 signaling [NCBI:1269502] [REACTOME:R-HSA-5684996] [PUBMED:25378393] [PUBMED:18199641] [PUBMED:17496909] [PUBMED:21779496] [PUBMED:15520807] [PUBMED:16393692] [PUBMED:19520853] [PUBMED:17496910] [PUBMED:22569528]
Metabolism [NCBI:1269956] [REACTOME:R-HSA-1430728]
Metabolism of carbohydrates [NCBI:1269957] [REACTOME:R-HSA-71387]
Misspliced GSK3beta mutants stabilize beta-catenin [NCBI:1268921] [REACTOME:R-HSA-5339716] [PUBMED:15306667] [PUBMED:19237556]
Mitotic Anaphase [NCBI:1269825] [REACTOME:R-HSA-68882]
Mitotic Metaphase and Anaphase [NCBI:1269823] [REACTOME:R-HSA-2555396]
Mitotic Prometaphase [NCBI:1269820] [REACTOME:R-HSA-68877]
MyD88 cascade initiated on plasma membrane [NCBI:1269207] [REACTOME:R-HSA-975871] [PUBMED:15728506] [PUBMED:16239509]
MyD88 dependent cascade initiated on endosome [NCBI:1269228] [REACTOME:R-HSA-975155] [PUBMED:20237413] [PUBMED:15276183] [PUBMED:18652679]
MyD88-independent TLR3/TLR4 cascade [NCBI:1269220] [REACTOME:R-HSA-166166] [PUBMED:15276183]
MyD88:Mal cascade initiated on plasma membrane [NCBI:1269237] [REACTOME:R-HSA-166058] [PUBMED:15276183]
NCAM signaling for neurite out-growth [NCBI:1270312] [REACTOME:R-HSA-375165] [PUBMED:18760361] [PUBMED:12587671] [PUBMED:15662836] [PUBMED:17975827] [PUBMED:15153429] [PUBMED:12700044]
NGF signalling via TRKA from the plasma membrane [NCBI:1269460] [REACTOME:R-HSA-187037] [PUBMED:11520933] [PUBMED:12676795] [PUBMED:10851172] [PUBMED:10579918]
Negative regulation of MAPK pathway [NCBI:1269288] [REACTOME:R-HSA-5675221] [PUBMED:15664191] [PUBMED:19219045] [PUBMED:19158341] [PUBMED:23443682] [PUBMED:16892053] [PUBMED:21779496] [PUBMED:17496916]
Negative regulation of the PI3K/AKT network [NCBI:1269191] [REACTOME:R-HSA-199418]
Nuclear Events (kinase and transcription factor activation) [NCBI:1269477] [REACTOME:R-HSA-198725] [PUBMED:8833451]
Oocyte meiosis [NCBI:126909] [KEGG:hsa04114] [PUBMED:16760654] [PUBMED:17480229] [PUBMED:15136768] [PUBMED:18946022] [PUBMED:18598214] [PUBMED:16518630] [PUBMED:18631137] [PUBMED:15182704] [PUBMED:15182701] [PUBMED:16554437] [PUBMED:14691134] [PUBMED:18550795] [PUBMED:18096427] [PUBMED:14517314] [PUBMED:18311174]
Opioid Signalling [NCBI:1269584] [REACTOME:R-HSA-111885] [PUBMED:9422713] [PUBMED:9218123] [PUBMED:16612131]
PI3K-Akt signaling pathway [NCBI:692234] [KEGG:hsa04151] [PUBMED:12048182] [PUBMED:11357143] [PUBMED:21440011] [PUBMED:15209374] [PUBMED:12669022] [PUBMED:18842113] [PUBMED:16847462] [PUBMED:12660731] [PUBMED:17360849] [PUBMED:9838078] [PUBMED:15505410] [PUBMED:16248975] [PUBMED:12531180] [PUBMED:21779440] [PUBMED:16187290] [PUBMED:15784165] [PUBMED:21620960]
PI3K/AKT activation [NCBI:1269473] [REACTOME:R-HSA-198203] [PUBMED:10579926] [PUBMED:12123609]
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling [NCBI:1383020] [REACTOME:R-HSA-6811558] [PUBMED:12422219] [PUBMED:16979564] [PUBMED:19805105] [PUBMED:17200115] [PUBMED:21827948] [PUBMED:19576174] [PUBMED:18753295] [PUBMED:19896968] [PUBMED:16456541] [PUBMED:25495341] [PUBMED:15464023] [PUBMED:23758345] [PUBMED:9367159] [PUBMED:9211928] [PUBMED:17245604]
PIP3 activates AKT signaling [NCBI:1269188] [REACTOME:R-HSA-1257604]
PP2A-mediated dephosphorylation of key metabolic factors [NCBI:1270113] [REACTOME:R-HSA-163767] [PUBMED:12721358]
Platelet homeostasis [NCBI:1269341] [REACTOME:R-HSA-418346] [PUBMED:10798271]
Platelet sensitization by LDL [NCBI:1269348] [REACTOME:R-HSA-432142] [PUBMED:12038793] [PUBMED:12775720] [PUBMED:15459198]
Presenilin action in Notch and Wnt signaling [NCBI:137914] [Pathway Interaction Database:ps1pathway] [PUBMED:10391247] [PUBMED:11921277] [PUBMED:11357136] [PUBMED:15620650] [PUBMED:11739397] [PUBMED:15747065] [PUBMED:10359821] [PUBMED:15327768] [PUBMED:12554650] [PUBMED:15292388] [PUBMED:11266469] [PUBMED:12794186] [PUBMED:10882062] [PUBMED:8923452] [PUBMED:12050670] [PUBMED:10201374] [PUBMED:12857724] [PUBMED:9171444]
Prolonged ERK activation events [NCBI:1269469] [REACTOME:R-HSA-169893] [PUBMED:12765839] [PUBMED:9069267]
RAF activation [NCBI:1269286] [REACTOME:R-HSA-5673000] [PUBMED:9689060] [PUBMED:16364920] [PUBMED:23993095] [PUBMED:17555829] [PUBMED:12865432] [PUBMED:11782426] [PUBMED:11296227] [PUBMED:12068308] [PUBMED:11447113] [PUBMED:11950876] [PUBMED:21779496] [PUBMED:20141835] [PUBMED:11296228] [PUBMED:15710605] [PUBMED:2993863] [PUBMED:11821947] [PUBMED:24937142] [PUBMED:11579234]
RAF/MAP kinase cascade [NCBI:1269285] [REACTOME:R-HSA-5673001] [PUBMED:21167873] [PUBMED:24937142] [PUBMED:20674547] [PUBMED:17496910] [PUBMED:22177953] [PUBMED:17496919] [PUBMED:22569528] [PUBMED:22535895] [PUBMED:12068308] [PUBMED:17496923] [PUBMED:19091303] [PUBMED:21372320] [PUBMED:21388974] [PUBMED:15520807]
RET signaling [NCBI:1427866] [REACTOME:R-HSA-8853659] [PUBMED:15013219] [PUBMED:17036197]
RHO GTPase Effectors [NCBI:1269509] [REACTOME:R-HSA-195258] [PUBMED:9694656] [PUBMED:18066052] [PUBMED:11018042] [PUBMED:10470034] [PUBMED:8702756] [PUBMED:21730051] [PUBMED:8571126] [PUBMED:19513348] [PUBMED:17244649] [PUBMED:11145705] [PUBMED:24128008] [PUBMED:23716662] [PUBMED:8617235] [PUBMED:8543060] [PUBMED:11804587] [PUBMED:24969695] [PUBMED:12635176] [PUBMED:12778124] [PUBMED:18006505] [PUBMED:1660188] [PUBMED:21351730] [PUBMED:16507994] [PUBMED:14595335] [PUBMED:10072071] [PUBMED:10591629] [PUBMED:10753910] [PUBMED:23875749] [PUBMED:17151359] [PUBMED:10652353] [PUBMED:12221077] [PUBMED:10559936] [PUBMED:12783890] [PUBMED:11948177] [PUBMED:18237546] [PUBMED:16079795] [PUBMED:10924361] [PUBMED:14514689] [PUBMED:8107774] [PUBMED:8756646] [PUBMED:16979770] [PUBMED:16636067] [PUBMED:9751706] [PUBMED:10619026] [PUBMED:23444367] [PUBMED:15546864] [PUBMED:12473120] [PUBMED:8816443] [PUBMED:9199170] [PUBMED:12514133] [PUBMED:16762923] [PUBMED:12110184] [PUBMED:16431929] [PUBMED:10975528] [PUBMED:10940294] [PUBMED:9535855] [PUBMED:7559638] [PUBMED:11162552] [PUBMED:19737400] [PUBMED:9988689] [PUBMED:12732141] [PUBMED:8798539] [PUBMED:24914801] [PUBMED:11689693] [PUBMED:8769096] [PUBMED:9368021]
RHO GTPases Activate Formins [NCBI:1269519] [REACTOME:R-HSA-5663220] [PUBMED:20233848] [PUBMED:15507212] [PUBMED:16292343] [PUBMED:12906795] [PUBMED:11779461] [PUBMED:21397845] [PUBMED:12577064] [PUBMED:17198702] [PUBMED:15006353] [PUBMED:20101212] [PUBMED:15944396] [PUBMED:10678165] [PUBMED:16943183] [PUBMED:16439214] [PUBMED:16472745] [PUBMED:10958683] [PUBMED:12732141] [PUBMED:15085137] [PUBMED:24914801] [PUBMED:9497258] [PUBMED:21576392] [PUBMED:21868368]
Resolution of Sister Chromatid Cohesion [NCBI:1269821] [REACTOME:R-HSA-2500257] [PUBMED:16541025] [PUBMED:15339662] [PUBMED:17112726] [PUBMED:9649503] [PUBMED:21111234] [PUBMED:15737063] [PUBMED:17113138] [PUBMED:21987589] [PUBMED:14730319] [PUBMED:11509732] [PUBMED:19696148] [PUBMED:21878504] [PUBMED:15723797]
Role of LAT2/NTAL/LAB on calcium mobilization [NCBI:1269302] [REACTOME:R-HSA-2730905] [PUBMED:17993265] [PUBMED:20643813] [PUBMED:17420272]
S33 mutants of beta-catenin aren't phosphorylated [NCBI:1268920] [REACTOME:R-HSA-5358747] [PUBMED:10487827] [PUBMED:12067995] [PUBMED:10921899] [PUBMED:18757411]
S37 mutants of beta-catenin aren't phosphorylated [NCBI:1268919] [REACTOME:R-HSA-5358749] [PUBMED:10487827] [PUBMED:12067995] [PUBMED:10921899]
S45 mutants of beta-catenin aren't phosphorylated [NCBI:1268917] [REACTOME:R-HSA-5358751] [PUBMED:9065402] [PUBMED:12000790] [PUBMED:10921899]
SHC1 events in EGFR signaling [NCBI:1269383] [REACTOME:R-HSA-180336] [PUBMED:11498013] [PUBMED:8755247]
SOS-mediated signalling [NCBI:1269440] [REACTOME:R-HSA-112412]
Separation of Sister Chromatids [NCBI:1269826] [REACTOME:R-HSA-2467813] [PUBMED:11081627] [PUBMED:10411507] [PUBMED:12070128] [PUBMED:12194817] [PUBMED:11509732]
Signal Transduction [NCBI:1269379] [REACTOME:R-HSA-162582] [PUBMED:17604717] [PUBMED:19648010] [PUBMED:16260143] [PUBMED:11742412] [PUBMED:19536106] [PUBMED:15863030] [PUBMED:19379690] [PUBMED:19458711] [PUBMED:19935667] [PUBMED:21252999] [PUBMED:15520807] [PUBMED:17496910] [PUBMED:15450248] [PUBMED:18043707] [PUBMED:16939974] [PUBMED:19762341] [PUBMED:18483217] [PUBMED:17084981] [PUBMED:21781017] [PUBMED:19619488]
Signaling by EGFR [NCBI:1269380] [REACTOME:R-HSA-177929] [PUBMED:10459005] [PUBMED:10404636] [PUBMED:12297041] [PUBMED:15142631]
Signaling by GPCR [NCBI:1269543] [REACTOME:R-HSA-372790] [PUBMED:16902930] [PUBMED:10202136] [PUBMED:18043707]
Signaling by Insulin receptor [NCBI:1269428] [REACTOME:R-HSA-74752] [PUBMED:8276779]
Signaling by Interleukins [NCBI:1269318] [REACTOME:R-HSA-449147] [PUBMED:19302047] [PUBMED:12445398]
Signaling by Leptin [NCBI:1269632] [REACTOME:R-HSA-2586552] [PUBMED:22211890] [PUBMED:23562747] [PUBMED:20600241] [PUBMED:21622208] [PUBMED:23579596] [PUBMED:22458591] [PUBMED:21489811] [PUBMED:19724019] [PUBMED:21331644] [PUBMED:22448029] [PUBMED:21147620] [PUBMED:20198122] [PUBMED:21677426] [PUBMED:20029269] [PUBMED:22249808] [PUBMED:22991412] [PUBMED:21527729] [PUBMED:17937601] [PUBMED:20553370] [PUBMED:21713385] [PUBMED:23565489] [PUBMED:22289780]
Signaling by PDGF [NCBI:1269478] [REACTOME:R-HSA-186797] [PUBMED:15207811] [PUBMED:10508235] [PUBMED:9739761]
Signaling by Rho GTPases [NCBI:1269507] [REACTOME:R-HSA-194315] [PUBMED:16212495] [PUBMED:15630019]
Signaling by SCF-KIT [NCBI:1269487] [REACTOME:R-HSA-1433557] [PUBMED:17350321] [PUBMED:16483568] [PUBMED:7688988] [PUBMED:19540337] [PUBMED:16475976] [PUBMED:15526160]
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) [NCBI:1269617] [REACTOME:R-HSA-2404192] [PUBMED:21042815] [PUBMED:18927274] [PUBMED:20098959] [PUBMED:17598937] [PUBMED:20975071] [PUBMED:22044904] [PUBMED:22649417]
Signaling by VEGF [NCBI:1269480] [REACTOME:R-HSA-194138] [PUBMED:15585754] [PUBMED:13678960] [PUBMED:16336962] [PUBMED:16835467]
Signaling by WNT in cancer [NCBI:1268906] [REACTOME:R-HSA-4791275] [PUBMED:7749328] [PUBMED:6318122] [PUBMED:22438566] [PUBMED:17510365] [PUBMED:10700176] [PUBMED:10733430] [PUBMED:17143297] [PUBMED:18311776] [PUBMED:11375957]
Signaling by Wnt [NCBI:1269594] [REACTOME:R-HSA-195721] [PUBMED:19530173] [PUBMED:23256519] [PUBMED:22952392] [PUBMED:19204114] [PUBMED:19365405] [PUBMED:19619488] [PUBMED:17143292] [PUBMED:17230199] [PUBMED:18710302] [PUBMED:16099039] [PUBMED:20576942] [PUBMED:10858654] [PUBMED:12967557]
Signaling by the B Cell Receptor (BCR) [NCBI:1269183] [REACTOME:R-HSA-983705] [PUBMED:1702903] [PUBMED:2011584] [PUBMED:1081164] [PUBMED:19065780] [PUBMED:16849466] [PUBMED:1375264] [PUBMED:7538118] [PUBMED:11901194] [PUBMED:8580068] [PUBMED:19249086] [PUBMED:18596693] [PUBMED:10648173] [PUBMED:4589993] [PUBMED:8163536] [PUBMED:1376928] [PUBMED:7688784] [PUBMED:6335036] [PUBMED:17052215] [PUBMED:18818202] [PUBMED:20206686] [PUBMED:7592958] [PUBMED:7524079] [PUBMED:15489917] [PUBMED:15509800] [PUBMED:18187424] [PUBMED:7927516] [PUBMED:803528] [PUBMED:19909372] [PUBMED:20192804] [PUBMED:8306975]
Signalling by NGF [NCBI:1269443] [REACTOME:R-HSA-166520]
Signalling to ERKs [NCBI:1269464] [REACTOME:R-HSA-187687] [PUBMED:10508738]
Signalling to RAS [NCBI:1269465] [REACTOME:R-HSA-167044] [PUBMED:11520933]
Signalling to p38 via RIT and RIN [NCBI:1269468] [REACTOME:R-HSA-187706] [PUBMED:10712923]
Sphingolipid signaling pathway [NCBI:1144995] [KEGG:hsa04071] [PUBMED:23919551] [PUBMED:21705677] [PUBMED:18675379] [PUBMED:20534702] [PUBMED:15999095] [PUBMED:16470226] [PUBMED:11001563] [PUBMED:17913601] [PUBMED:17161984] [PUBMED:22654878] [PUBMED:17438574] [PUBMED:18216770] [PUBMED:11418646] [PUBMED:10880336] [PUBMED:15451787] [PUBMED:25309325] [PUBMED:18403224]
T41 mutants of beta-catenin aren't phosphorylated [NCBI:1268918] [REACTOME:R-HSA-5358752] [PUBMED:12101426] [PUBMED:12439748] [PUBMED:22438566] [PUBMED:10921899] [PUBMED:23256519]
TCF dependent signaling in response to WNT [NCBI:1269599] [REACTOME:R-HSA-201681] [PUBMED:19619488] [PUBMED:23256519] [PUBMED:23343194]
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation [NCBI:1269229] [REACTOME:R-HSA-975138] [PUBMED:22511786] [PUBMED:18794297]
TRIF-mediated TLR3/TLR4 signaling [NCBI:1269221] [REACTOME:R-HSA-937061] [PUBMED:15814722] [PUBMED:12855817] [PUBMED:14739303]
Toll Like Receptor 10 (TLR10) Cascade [NCBI:1269206] [REACTOME:R-HSA-168142] [PUBMED:15728506] [PUBMED:18332149]
Toll Like Receptor 2 (TLR2) Cascade [NCBI:1269238] [REACTOME:R-HSA-181438] [PUBMED:10820283]
Toll Like Receptor 3 (TLR3) Cascade [NCBI:1269219] [REACTOME:R-HSA-168164] [PUBMED:19627256] [PUBMED:15733829] [PUBMED:18202435]
Toll Like Receptor 4 (TLR4) Cascade [NCBI:1269234] [REACTOME:R-HSA-166016]
Toll Like Receptor 5 (TLR5) Cascade [NCBI:1269226] [REACTOME:R-HSA-168176] [PUBMED:11489966] [PUBMED:11323673]
Toll Like Receptor 7/8 (TLR7/8) Cascade [NCBI:1269227] [REACTOME:R-HSA-168181] [PUBMED:14976262]
Toll Like Receptor 9 (TLR9) Cascade [NCBI:1269233] [REACTOME:R-HSA-168138] [PUBMED:14751759]
Toll Like Receptor TLR1:TLR2 Cascade [NCBI:1269239] [REACTOME:R-HSA-168179] [PUBMED:12975352]
Toll Like Receptor TLR6:TLR2 Cascade [NCBI:1269240] [REACTOME:R-HSA-168188] [PUBMED:14977973]
Toll-Like Receptors Cascades [NCBI:1269204] [REACTOME:R-HSA-168898] [PUBMED:15950447] [PUBMED:12893815] [PUBMED:15976490] [PUBMED:15585605] [PUBMED:14751757]
Truncations of AMER1 destabilize the destruction complex [NCBI:1268915] [REACTOME:R-HSA-5467348] [PUBMED:19760609] [PUBMED:18311776] [PUBMED:17510365] [PUBMED:21248786]
VEGFA-VEGFR2 Pathway [NCBI:1269483] [REACTOME:R-HSA-4420097] [PUBMED:17344076] [PUBMED:16633338] [PUBMED:19230644] [PUBMED:13678960]
VEGFR2 mediated cell proliferation [NCBI:1269485] [REACTOME:R-HSA-5218921] [PUBMED:22866201] [PUBMED:22180219] [PUBMED:22762016]
mRNA surveillance pathway [NCBI:193328] [KEGG:hsa03015] [PUBMED:16723977] [PUBMED:18158581] [PUBMED:16715045] [PUBMED:17183357] [PUBMED:15040442]
phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex [NCBI:1268916] [REACTOME:R-HSA-4839743] [PUBMED:9601641] [PUBMED:10733430] [PUBMED:9065402] [PUBMED:23256519] [PUBMED:11375957] [PUBMED:9065403]
truncated APC mutants destabilize the destruction complex [NCBI:1268907] [REACTOME:R-HSA-4839744] [PUBMED:1338904] [PUBMED:8756721] [PUBMED:9065402] [PUBMED:17143297] [PUBMED:23256519] [PUBMED:8111410] [PUBMED:23169527] [PUBMED:15327768] [PUBMED:22761442] [PUBMED:10921899] [PUBMED:9065401]