full name
acyl-CoA dehydrogenase, C-4 to C-12 straight chain

synonyms
ACAD1, MCAD, MCADH, ACADM, ENSG00000117054

HGNC
HGNC:89

Entrez Gene
Gene:34

ENSEMBL
ENSG00000117054

location
chr: 1
start: 76190043
stop: 76229355
strand: +

OMIM
OMIM:607008: ACADM (Autosomal recessive inheritance)
OMIM:201450: Acyl-CoA dehydrogenase, medium chain, deficiency of

transcripts
NM_001127328.1
NM_000016.4

pathways
Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA [NCBI:1270020] [REACTOME:R-HSA-77346]
Beta oxidation of octanoyl-CoA to hexanoyl-CoA [NCBI:1270021] [REACTOME:R-HSA-77348]
Carbon metabolism [NCBI:814926] [KEGG:hsa01200]
FOXA2 and FOXA3 transcription factor networks [NCBI:137911] [Pathway Interaction Database:hnf3bpathway] [PUBMED:14500912] [PUBMED:9632808] [PUBMED:8668179] [PUBMED:2786140] [PUBMED:10748140] [PUBMED:8662915] [PUBMED:12865419] [PUBMED:12145169] [PUBMED:15314688] [PUBMED:12911579] [PUBMED:15123725] [PUBMED:16098831] [PUBMED:10455192] [PUBMED:15616563] [PUBMED:7524494] [PUBMED:7565696] [PUBMED:15959514] [PUBMED:11278466] [PUBMED:9369482] [PUBMED:8813720]
Fatty acid degradation [NCBI:82935] [KEGG:hsa00071] [PUBMED:869535]
Fatty acid metabolism [NCBI:868084] [KEGG:hsa01212]
Fatty acid, triacylglycerol, and ketone body metabolism [NCBI:1270010] [REACTOME:R-HSA-535734]
Leucine degradation, leucine => acetoacetate + acetyl-CoA [NCBI:413354] [KEGG:hsa_M00036]
Malonate semialdehyde pathway, propanoyl-CoA => acetyl-CoA [NCBI:413478] [KEGG:hsa_M00013]
Metabolic pathways [NCBI:132956] [KEGG:hsa01100]
Metabolism [NCBI:1269956] [REACTOME:R-HSA-1430728]
Metabolism of lipids and lipoproteins [NCBI:1270001] [REACTOME:R-HSA-556833]
Mitochondrial Fatty Acid Beta-Oxidation [NCBI:1270015] [REACTOME:R-HSA-77289] [PUBMED:10527676] [PUBMED:11826276] [PUBMED:7951672] [PUBMED:1431593]
PPAR signaling pathway [NCBI:83042] [KEGG:hsa03320] [PUBMED:15673477] [PUBMED:15828221] [PUBMED:14999402] [PUBMED:15828222] [PUBMED:16601267] [PUBMED:15828220] [PUBMED:10529898] [PUBMED:15828223] [PUBMED:16476485] [PUBMED:11921433] [PUBMED:16511590] [PUBMED:16360030]
PPARA activates gene expression [NCBI:1270030] [REACTOME:R-HSA-1989781] [PUBMED:10529898] [PUBMED:18288277] [PUBMED:11330046] [PUBMED:20936127] [PUBMED:14999402]
Propanoate metabolism [NCBI:83004] [KEGG:hsa00640]
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) [NCBI:1270029] [REACTOME:R-HSA-400206] [PUBMED:18288277] [PUBMED:10529898] [PUBMED:16476485] [PUBMED:16503871]
Valine, leucine and isoleucine degradation [NCBI:82952] [KEGG:hsa00280]
beta-Alanine metabolism [NCBI:82966] [KEGG:hsa00410]
beta-Oxidation [NCBI:413381] [KEGG:hsa_M00087]
mitochondrial fatty acid beta-oxidation of saturated fatty acids [NCBI:1270016] [REACTOME:R-HSA-77286]
mitochondrial fatty acid beta-oxidation of unsaturated fatty acids [NCBI:1270024] [REACTOME:R-HSA-77288]