full name
acyl-CoA dehydrogenase, C-4 to C-12 straight chain
synonyms
ACAD1, MCAD, MCADH, ACADM, ENSG00000117054
HGNC
HGNC:89
Entrez Gene
Gene:34
ENSEMBL
ENSG00000117054
location
chr: 1
start: 76190043
stop: 76229355
strand: +
OMIM
OMIM:607008:
ACADM
(Autosomal recessive inheritance)
OMIM:201450:
Acyl-CoA dehydrogenase, medium chain, deficiency of
transcripts
NM_001127328.1
NM_000016.4
pathways
Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA
[NCBI:1270020]
[REACTOME:R-HSA-77346]
Beta oxidation of octanoyl-CoA to hexanoyl-CoA
[NCBI:1270021]
[REACTOME:R-HSA-77348]
Carbon metabolism
[NCBI:814926]
[KEGG:hsa01200]
FOXA2 and FOXA3 transcription factor networks
[NCBI:137911]
[Pathway Interaction Database:hnf3bpathway]
[PUBMED:14500912]
[PUBMED:9632808]
[PUBMED:8668179]
[PUBMED:2786140]
[PUBMED:10748140]
[PUBMED:8662915]
[PUBMED:12865419]
[PUBMED:12145169]
[PUBMED:15314688]
[PUBMED:12911579]
[PUBMED:15123725]
[PUBMED:16098831]
[PUBMED:10455192]
[PUBMED:15616563]
[PUBMED:7524494]
[PUBMED:7565696]
[PUBMED:15959514]
[PUBMED:11278466]
[PUBMED:9369482]
[PUBMED:8813720]
Fatty acid degradation
[NCBI:82935]
[KEGG:hsa00071]
[PUBMED:869535]
Fatty acid metabolism
[NCBI:868084]
[KEGG:hsa01212]
Fatty acid, triacylglycerol, and ketone body metabolism
[NCBI:1270010]
[REACTOME:R-HSA-535734]
Leucine degradation, leucine => acetoacetate + acetyl-CoA
[NCBI:413354]
[KEGG:hsa_M00036]
Malonate semialdehyde pathway, propanoyl-CoA => acetyl-CoA
[NCBI:413478]
[KEGG:hsa_M00013]
Metabolic pathways
[NCBI:132956]
[KEGG:hsa01100]
Metabolism
[NCBI:1269956]
[REACTOME:R-HSA-1430728]
Metabolism of lipids and lipoproteins
[NCBI:1270001]
[REACTOME:R-HSA-556833]
Mitochondrial Fatty Acid Beta-Oxidation
[NCBI:1270015]
[REACTOME:R-HSA-77289]
[PUBMED:10527676]
[PUBMED:11826276]
[PUBMED:7951672]
[PUBMED:1431593]
PPAR signaling pathway
[NCBI:83042]
[KEGG:hsa03320]
[PUBMED:15673477]
[PUBMED:15828221]
[PUBMED:14999402]
[PUBMED:15828222]
[PUBMED:16601267]
[PUBMED:15828220]
[PUBMED:10529898]
[PUBMED:15828223]
[PUBMED:16476485]
[PUBMED:11921433]
[PUBMED:16511590]
[PUBMED:16360030]
PPARA activates gene expression
[NCBI:1270030]
[REACTOME:R-HSA-1989781]
[PUBMED:10529898]
[PUBMED:18288277]
[PUBMED:11330046]
[PUBMED:20936127]
[PUBMED:14999402]
Propanoate metabolism
[NCBI:83004]
[KEGG:hsa00640]
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
[NCBI:1270029]
[REACTOME:R-HSA-400206]
[PUBMED:18288277]
[PUBMED:10529898]
[PUBMED:16476485]
[PUBMED:16503871]
Valine, leucine and isoleucine degradation
[NCBI:82952]
[KEGG:hsa00280]
beta-Alanine metabolism
[NCBI:82966]
[KEGG:hsa00410]
beta-Oxidation
[NCBI:413381]
[KEGG:hsa_M00087]
mitochondrial fatty acid beta-oxidation of saturated fatty acids
[NCBI:1270016]
[REACTOME:R-HSA-77286]
mitochondrial fatty acid beta-oxidation of unsaturated fatty acids
[NCBI:1270024]
[REACTOME:R-HSA-77288]
