Logo
full name
WAS protein family member 1

synonyms
SCAR1, WAVE, WAVE1, WASF1, ENSG00000112290

HGNC
HGNC:12732

Entrez Gene
Gene:8936

ENSEMBL
ENSG00000112290

location
chr: 6
start: 110421022
stop: 110501219
strand: -

transcripts
NM_001024936.1
NM_001024935.1
NM_001024934.1
NM_003931.2

pathways
Adherens junction [NCBI:83070] [KEGG:hsa04520] [PUBMED:11703922] [PUBMED:10890911] [PUBMED:15551862] [PUBMED:15561584] [PUBMED:10959047] [PUBMED:11984870] [PUBMED:10204118] [PUBMED:15489912] [PUBMED:14623871] [PUBMED:15001769] [PUBMED:12640114] [PUBMED:12665527] [PUBMED:11171368]
Bacterial invasion of epithelial cells [NCBI:149807] [KEGG:hsa05100] [PUBMED:17298394] [PUBMED:16406780] [PUBMED:19185531] [PUBMED:19157959] [PUBMED:17719540] [PUBMED:19296488]
Choline metabolism in cancer [NCBI:1059539] [KEGG:hsa05231] [PUBMED:23076158] [PUBMED:19264150] [PUBMED:16230400] [PUBMED:23350810] [PUBMED:22429397] [PUBMED:16432178] [PUBMED:19136975] [PUBMED:22089420] [PUBMED:14517341] [PUBMED:22921309] [PUBMED:19855431] [PUBMED:20528734] [PUBMED:19935796] [PUBMED:14523987] [PUBMED:21793073]
E2F transcription factor network [NCBI:137934] [Pathway Interaction Database:e2f_pathway] [PUBMED:15175242] [PUBMED:11034215] [PUBMED:8832394] [PUBMED:7479977] [PUBMED:12077144] [PUBMED:11274364] [PUBMED:8618861] [PUBMED:11857079] [PUBMED:7958837] [PUBMED:15014447] [PUBMED:9774682] [PUBMED:9704927] [PUBMED:9271400] [PUBMED:8334989] [PUBMED:16288221] [PUBMED:10766737] [PUBMED:8657141] [PUBMED:8552092] [PUBMED:11101847] [PUBMED:12757710] [PUBMED:17704056] [PUBMED:7705662] [PUBMED:15897886] [PUBMED:9192872] [PUBMED:9778043] [PUBMED:12766778] [PUBMED:15510213] [PUBMED:11418595] [PUBMED:10454584] [PUBMED:10783242] [PUBMED:11904439] [PUBMED:16179649] [PUBMED:7791762] [PUBMED:11719808] [PUBMED:12389032] [PUBMED:8264596] [PUBMED:19491197] [PUBMED:15713665] [PUBMED:16357170] [PUBMED:9689056] [PUBMED:12748276] [PUBMED:2524830] [PUBMED:14633988] [PUBMED:12697828] [PUBMED:12101096] [PUBMED:11799067] [PUBMED:15133492] [PUBMED:16892051] [PUBMED:8943353] [PUBMED:9724731] [PUBMED:10030670] [PUBMED:11459832] [PUBMED:8114719] [PUBMED:9520412] [PUBMED:18348985] [PUBMED:9020173] [PUBMED:11389439] [PUBMED:16211008] [PUBMED:12411495] [PUBMED:7958836] [PUBMED:12909625] [PUBMED:15306814] [PUBMED:10688648] [PUBMED:12611887] [PUBMED:9191053] [PUBMED:10373518] [PUBMED:10187822]
Fc gamma R-mediated phagocytosis [NCBI:114228] [KEGG:hsa04666] [PUBMED:11304556] [PUBMED:11244038] [PUBMED:10755615] [PUBMED:17308335] [PUBMED:12821647] [PUBMED:15466916] [PUBMED:17050193] [PUBMED:11228151] [PUBMED:12488490] [PUBMED:10224668] [PUBMED:11708889] [PUBMED:9581795] [PUBMED:10586078] [PUBMED:9417101] [PUBMED:15485887] [PUBMED:18322649] [PUBMED:10577498] [PUBMED:10376013] [PUBMED:10601359] [PUBMED:9545263]
Fcgamma receptor (FCGR) dependent phagocytosis [NCBI:1269279] [REACTOME:R-HSA-2029480] [PUBMED:8541526] [PUBMED:12488490] [PUBMED:16413920] [PUBMED:17050193]
Immune System [NCBI:1269170] [REACTOME:R-HSA-168256]
Innate Immune System [NCBI:1269203] [REACTOME:R-HSA-168249]
RAC1 signaling pathway [NCBI:169355] [Pathway Interaction Database:rac1_pathway] [PUBMED:19158278] [PUBMED:16702231] [PUBMED:16440308] [PUBMED:14765121] [PUBMED:12453877] [PUBMED:12657629] [PUBMED:9799233] [PUBMED:9694656] [PUBMED:9317150] [PUBMED:14970210] [PUBMED:8305740] [PUBMED:8805275] [PUBMED:17178910] [PUBMED:11060298] [PUBMED:11304531] [PUBMED:11804587] [PUBMED:11470914] [PUBMED:11309380] [PUBMED:17244649] [PUBMED:11021801] [PUBMED:7592586] [PUBMED:15681696] [PUBMED:7744004] [PUBMED:15225553] [PUBMED:10559936] [PUBMED:19917258] [PUBMED:7600581] [PUBMED:19363480] [PUBMED:18423204] [PUBMED:20097736] [PUBMED:19852956] [PUBMED:12181570] [PUBMED:19822663] [PUBMED:7652575] [PUBMED:7629060] [PUBMED:8107774] [PUBMED:16636067] [PUBMED:9042860] [PUBMED:12213441] [PUBMED:10679324] [PUBMED:12682053] [PUBMED:18198193] [PUBMED:16542153] [PUBMED:7600582] [PUBMED:18948007] [PUBMED:18319301] [PUBMED:10559253] [PUBMED:17115053] [PUBMED:10473551] [PUBMED:17682062] [PUBMED:17164293] [PUBMED:15557278] [PUBMED:15677464] [PUBMED:16837009] [PUBMED:12796474] [PUBMED:10559863] [PUBMED:9535855] [PUBMED:8910292] [PUBMED:11432831] [PUBMED:17981134] [PUBMED:16762923] [PUBMED:8798539] [PUBMED:18160398] [PUBMED:16099876] [PUBMED:14681219]
RHO GTPase Effectors [NCBI:1269509] [REACTOME:R-HSA-195258] [PUBMED:9694656] [PUBMED:18066052] [PUBMED:11018042] [PUBMED:10470034] [PUBMED:8702756] [PUBMED:21730051] [PUBMED:8571126] [PUBMED:19513348] [PUBMED:17244649] [PUBMED:11145705] [PUBMED:24128008] [PUBMED:23716662] [PUBMED:8617235] [PUBMED:8543060] [PUBMED:11804587] [PUBMED:24969695] [PUBMED:12635176] [PUBMED:12778124] [PUBMED:18006505] [PUBMED:1660188] [PUBMED:21351730] [PUBMED:16507994] [PUBMED:14595335] [PUBMED:10072071] [PUBMED:10591629] [PUBMED:10753910] [PUBMED:23875749] [PUBMED:17151359] [PUBMED:10652353] [PUBMED:12221077] [PUBMED:10559936] [PUBMED:12783890] [PUBMED:11948177] [PUBMED:18237546] [PUBMED:16079795] [PUBMED:10924361] [PUBMED:14514689] [PUBMED:8107774] [PUBMED:8756646] [PUBMED:16979770] [PUBMED:16636067] [PUBMED:9751706] [PUBMED:10619026] [PUBMED:23444367] [PUBMED:15546864] [PUBMED:12473120] [PUBMED:8816443] [PUBMED:9199170] [PUBMED:12514133] [PUBMED:16762923] [PUBMED:12110184] [PUBMED:16431929] [PUBMED:10975528] [PUBMED:10940294] [PUBMED:9535855] [PUBMED:7559638] [PUBMED:11162552] [PUBMED:19737400] [PUBMED:9988689] [PUBMED:12732141] [PUBMED:8798539] [PUBMED:24914801] [PUBMED:11689693] [PUBMED:8769096] [PUBMED:9368021]
RHO GTPases Activate WASPs and WAVEs [NCBI:1269518] [REACTOME:R-HSA-5663213] [PUBMED:24969695]
Regulation of actin cytoskeleton [NCBI:83089] [KEGG:hsa04810] [PUBMED:11152757] [PUBMED:11082272] [PUBMED:10574699] [PUBMED:11082269] [PUBMED:14657486] [PUBMED:14744429] [PUBMED:12700767]
Regulation of actin dynamics for phagocytic cup formation [NCBI:1269281] [REACTOME:R-HSA-2029482] [PUBMED:17477841] [PUBMED:15452139] [PUBMED:15981459]
Salmonella infection [NCBI:375172] [KEGG:hsa05132] [PUBMED:18407067] [PUBMED:18411289] [PUBMED:18778407] [PUBMED:20123714] [PUBMED:20158475] [PUBMED:19779561] [PUBMED:18026123] [PUBMED:19930040] [PUBMED:12675800] [PUBMED:11755407] [PUBMED:11489966] [PUBMED:19775254] [PUBMED:20943123] [PUBMED:17690885] [PUBMED:16938850] [PUBMED:20526845] [PUBMED:11567004] [PUBMED:17074883] [PUBMED:11825778] [PUBMED:17071592] [PUBMED:16800847] [PUBMED:16611232] [PUBMED:10499590]
Shigellosis [NCBI:83104] [KEGG:hsa05131] [PUBMED:11379633] [PUBMED:10491394] [PUBMED:17173036] [PUBMED:18202440] [PUBMED:17095701] [PUBMED:16622194] [PUBMED:16413487] [PUBMED:18005683] [PUBMED:15731041] [PUBMED:15073367] [PUBMED:12856283] [PUBMED:16939534] [PUBMED:17060328] [PUBMED:12065406] [PUBMED:8376337] [PUBMED:11207560] [PUBMED:8642302] [PUBMED:12356723] [PUBMED:15694852] [PUBMED:10369666] [PUBMED:14638419] [PUBMED:16441429] [PUBMED:16162672] [PUBMED:17719540] [PUBMED:7665485] [PUBMED:18059288] [PUBMED:18005697] [PUBMED:19165331] [PUBMED:12828640] [PUBMED:17662586] [PUBMED:9176079] [PUBMED:7591128] [PUBMED:15318166] [PUBMED:15950937]
Signal Transduction [NCBI:1269379] [REACTOME:R-HSA-162582] [PUBMED:17604717] [PUBMED:19648010] [PUBMED:16260143] [PUBMED:11742412] [PUBMED:19536106] [PUBMED:15863030] [PUBMED:19379690] [PUBMED:19458711] [PUBMED:19935667] [PUBMED:21252999] [PUBMED:15520807] [PUBMED:17496910] [PUBMED:15450248] [PUBMED:18043707] [PUBMED:16939974] [PUBMED:19762341] [PUBMED:18483217] [PUBMED:17084981] [PUBMED:21781017] [PUBMED:19619488]
Signaling by Rho GTPases [NCBI:1269507] [REACTOME:R-HSA-194315] [PUBMED:16212495] [PUBMED:15630019]
Signaling by VEGF [NCBI:1269480] [REACTOME:R-HSA-194138] [PUBMED:15585754] [PUBMED:13678960] [PUBMED:16336962] [PUBMED:16835467]
VEGFA-VEGFR2 Pathway [NCBI:1269483] [REACTOME:R-HSA-4420097] [PUBMED:17344076] [PUBMED:16633338] [PUBMED:19230644] [PUBMED:13678960]