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Genes
SGK1
Gene - SGK1
full name
serum/glucocorticoid regulated kinase 1
synonyms
SGK, SGK1, ENSG00000118515
HGNC
HGNC:10810
Entrez Gene
Gene:6446
ENSEMBL
ENSG00000118515
location
chr: 6
start: 134490384
stop: 134639196
strand: -
transcripts
NM_001143676.1
NM_001143677.1
NM_001143678.1
NM_005627.3
pathways
Aldosterone-regulated sodium reabsorption
[NCBI:130626]
[KEGG:hsa04960]
[PUBMED:17332888]
[PUBMED:12943727]
[PUBMED:11208606]
[PUBMED:18197893]
[PUBMED:19549592]
[PUBMED:12649599]
[PUBMED:16286565]
[PUBMED:15590995]
[PUBMED:11850323]
[PUBMED:17309947]
[PUBMED:18174920]
[PUBMED:16002531]
Class I PI3K signaling events
[NCBI:138022]
[Pathway Interaction Database:pi3kcipathway]
[PUBMED:9072969]
[PUBMED:15296756]
[PUBMED:12780340]
[PUBMED:11154281]
[PUBMED:9326591]
[PUBMED:10357815]
[PUBMED:10586033]
[PUBMED:9824312]
[PUBMED:11001876]
[PUBMED:9593664]
[PUBMED:10770799]
[PUBMED:9442017]
[PUBMED:8643691]
[PUBMED:7627555]
[PUBMED:11102801]
[PUBMED:9307042]
[PUBMED:10506192]
[PUBMED:11804589]
[PUBMED:15879121]
[PUBMED:11226282]
[PUBMED:18024423]
[PUBMED:8629002]
[PUBMED:9550703]
[PUBMED:14688341]
[PUBMED:16418224]
[PUBMED:8945478]
[PUBMED:10333475]
[PUBMED:10764758]
[PUBMED:9417041]
[PUBMED:8052307]
FoxO family signaling
[NCBI:138036]
[Pathway Interaction Database:foxopathway]
[PUBMED:17038621]
[PUBMED:15788402]
[PUBMED:14976264]
[PUBMED:11864996]
[PUBMED:12517744]
[PUBMED:11050388]
[PUBMED:10960473]
[PUBMED:10783894]
[PUBMED:11154281]
[PUBMED:11313479]
[PUBMED:11777915]
[PUBMED:11980723]
[PUBMED:10102273]
[PUBMED:15509806]
[PUBMED:11237865]
[PUBMED:16751106]
[PUBMED:12857750]
[PUBMED:15538382]
[PUBMED:12239572]
[PUBMED:12048180]
[PUBMED:11884717]
[PUBMED:11884591]
[PUBMED:15084260]
[PUBMED:11964479]
[PUBMED:10217147]
[PUBMED:15109499]
[PUBMED:16964248]
[PUBMED:15905404]
[PUBMED:11607034]
[PUBMED:15668399]
[PUBMED:15220471]
[PUBMED:10358075]
[PUBMED:16424905]
FoxO signaling pathway
[NCBI:921162]
[KEGG:hsa04068]
[PUBMED:23325358]
[PUBMED:15005655]
[PUBMED:18951090]
[PUBMED:22761423]
[PUBMED:22902436]
[PUBMED:16288288]
[PUBMED:19701188]
[PUBMED:16964248]
[PUBMED:18045156]
[PUBMED:18403263]
[PUBMED:21613825]
[PUBMED:21440011]
[PUBMED:17470511]
[PUBMED:21238503]
[PUBMED:17522590]
[PUBMED:15084259]
[PUBMED:23801966]
[PUBMED:17569704]
[PUBMED:15516968]
Gene Expression
[NCBI:1269649]
[REACTOME:R-HSA-74160]
Generic Transcription Pathway
[NCBI:1269650]
[REACTOME:R-HSA-212436]
[PUBMED:15175151]
[PUBMED:14744435]
[PUBMED:15680972]
[PUBMED:11395415]
[PUBMED:15896744]
[PUBMED:10235266]
[PUBMED:14986688]
[PUBMED:12023297]
[PUBMED:15680973]
[PUBMED:16751179]
[PUBMED:11861166]
[PUBMED:16429119]
[PUBMED:16719718]
[PUBMED:16921404]
[PUBMED:15690163]
Glucocorticoid receptor regulatory network
[NCBI:138014]
[Pathway Interaction Database:reg_gr_pathway]
[PUBMED:8943293]
[PUBMED:1708774]
[PUBMED:15826950]
[PUBMED:11027313]
[PUBMED:12118039]
[PUBMED:9388207]
[PUBMED:11751894]
[PUBMED:12151000]
[PUBMED:9765258]
[PUBMED:9407028]
[PUBMED:19074285]
[PUBMED:2838908]
[PUBMED:15817653]
[PUBMED:9722596]
[PUBMED:12917342]
[PUBMED:1387550]
[PUBMED:10974006]
[PUBMED:15790729]
[PUBMED:10825196]
[PUBMED:10623828]
[PUBMED:2169352]
[PUBMED:9315653]
[PUBMED:7759501]
[PUBMED:8290595]
[PUBMED:2905764]
[PUBMED:12351702]
[PUBMED:11080152]
[PUBMED:8428574]
[PUBMED:9215863]
[PUBMED:15459252]
[PUBMED:10400612]
[PUBMED:9426156]
[PUBMED:17440046]
[PUBMED:18838540]
[PUBMED:2169353]
[PUBMED:10820245]
[PUBMED:12511605]
[PUBMED:2586521]
[PUBMED:1740658]
[PUBMED:11555652]
[PUBMED:11562347]
[PUBMED:9482836]
[PUBMED:18337589]
[PUBMED:10958685]
[PUBMED:9388192]
[PUBMED:15834420]
[PUBMED:15657031]
[PUBMED:8878484]
[PUBMED:10760263]
[PUBMED:12730237]
[PUBMED:8702844]
[PUBMED:2169351]
[PUBMED:17215482]
[PUBMED:8898375]
Insulin Pathway
[NCBI:138026]
[Pathway Interaction Database:insulin_pathway]
[PUBMED:8491186]
[PUBMED:9111325]
[PUBMED:7629070]
[PUBMED:10499514]
[PUBMED:11121405]
[PUBMED:10660596]
[PUBMED:8196603]
[PUBMED:11096081]
[PUBMED:8524328]
[PUBMED:9891043]
[PUBMED:12242347]
[PUBMED:2123524]
[PUBMED:9369444]
[PUBMED:1375946]
[PUBMED:9348199]
[PUBMED:8826975]
[PUBMED:8316835]
[PUBMED:8999839]
[PUBMED:8449939]
[PUBMED:10807907]
[PUBMED:1599438]
[PUBMED:8265614]
[PUBMED:11171109]
[PUBMED:11821390]
[PUBMED:12687004]
[PUBMED:7806540]
[PUBMED:11154281]
[PUBMED:8244979]
[PUBMED:8798417]
[PUBMED:1381348]
[PUBMED:7581368]
[PUBMED:15787604]
[PUBMED:8385105]
[PUBMED:11551902]
[PUBMED:8114695]
[PUBMED:11997497]
[PUBMED:11001060]
[PUBMED:11309621]
[PUBMED:9109420]
[PUBMED:8383963]
[PUBMED:12147684]
[PUBMED:8144662]
[PUBMED:12036959]
[PUBMED:14734537]
[PUBMED:7983051]
[PUBMED:9083103]
[PUBMED:15210700]
[PUBMED:9065430]
[PUBMED:11297536]
[PUBMED:10544179]
[PUBMED:1321126]
[PUBMED:11502760]
[PUBMED:8978681]
[PUBMED:8999972]
[PUBMED:14690593]
[PUBMED:11832334]
[PUBMED:9447983]
[PUBMED:15192089]
[PUBMED:8524413]
[PUBMED:7685165]
[PUBMED:10329736]
[PUBMED:11287630]
[PUBMED:15486046]
[PUBMED:10330191]
[PUBMED:8626723]
Ion channel transport
[NCBI:1269950]
[REACTOME:R-HSA-983712]
[PUBMED:15071553]
PI3K-Akt signaling pathway
[NCBI:692234]
[KEGG:hsa04151]
[PUBMED:12048182]
[PUBMED:11357143]
[PUBMED:21440011]
[PUBMED:15209374]
[PUBMED:12669022]
[PUBMED:18842113]
[PUBMED:16847462]
[PUBMED:12660731]
[PUBMED:17360849]
[PUBMED:9838078]
[PUBMED:15505410]
[PUBMED:16248975]
[PUBMED:12531180]
[PUBMED:21779440]
[PUBMED:16187290]
[PUBMED:15784165]
[PUBMED:21620960]
Regulation of TP53 Activity
[NCBI:1383076]
[REACTOME:R-HSA-5633007]
[PUBMED:19450511]
[PUBMED:20457558]
[PUBMED:23825024]
[PUBMED:25641576]
Regulation of TP53 Degradation
[NCBI:1383079]
[REACTOME:R-HSA-6804757]
[PUBMED:21730132]
[PUBMED:10570149]
[PUBMED:15563468]
[PUBMED:16845383]
[PUBMED:11923872]
[PUBMED:11883935]
[PUBMED:17290220]
[PUBMED:17121812]
[PUBMED:10673500]
[PUBMED:9843217]
[PUBMED:9529249]
[PUBMED:21730163]
[PUBMED:11715018]
[PUBMED:9733514]
[PUBMED:19838211]
[PUBMED:10608892]
[PUBMED:16474402]
[PUBMED:19450511]
[PUBMED:16163388]
[PUBMED:10722742]
[PUBMED:21986495]
[PUBMED:15788536]
[PUBMED:19816404]
[PUBMED:11359766]
[PUBMED:11504915]
[PUBMED:9733515]
[PUBMED:19756449]
[PUBMED:11983168]
[PUBMED:8319905]
[PUBMED:20438709]
Regulation of TP53 Expression and Degradation
[NCBI:1383077]
[REACTOME:R-HSA-6806003]
[PUBMED:11883935]
[PUBMED:11923872]
[PUBMED:19293287]
[PUBMED:23303139]
[PUBMED:17499002]
[PUBMED:15563468]
[PUBMED:17121812]
[PUBMED:21986495]
[PUBMED:15103385]
[PUBMED:9529249]
[PUBMED:21814038]
[PUBMED:19250907]
[PUBMED:8319905]
[PUBMED:7878469]
[PUBMED:12654245]
[PUBMED:16213212]
Stimuli-sensing channels
[NCBI:1269953]
[REACTOME:R-HSA-2672351]
[PUBMED:15728426]
[PUBMED:16460286]
[PUBMED:12907679]
[PUBMED:18391176]
[PUBMED:19278523]
[PUBMED:11904445]
[PUBMED:22934072]
[PUBMED:20807551]
[PUBMED:19783045]
[PUBMED:16219661]
[PUBMED:21932071]
[PUBMED:22277752]
Transcriptional Regulation by TP53
[NCBI:1269654]
[REACTOME:R-HSA-3700989]
[PUBMED:26122615]
[PUBMED:19410540]
Transmembrane transport of small molecules
[NCBI:1269903]
[REACTOME:R-HSA-382551]
mTOR signaling pathway
[NCBI:83059]
[KEGG:hsa04150]
[NCBI:138001]
[Pathway Interaction Database:mtor_4pathway]
[PUBMED:17277771]
[PUBMED:15341740]
[PUBMED:12172553]
[PUBMED:15718470]
[PUBMED:14651849]
[PUBMED:15268862]
[PUBMED:15306821]
[PUBMED:26046644]
[PUBMED:12869586]
[PUBMED:24556838]
[PUBMED:17928295]
[PUBMED:9427642]
[PUBMED:18046414]
[PUBMED:12912918]
[PUBMED:16286006]
[PUBMED:26658722]
[PUBMED:24842496]
[PUBMED:23465396]
[PUBMED:17709744]
[PUBMED:17599906]
[PUBMED:16919458]
[PUBMED:10364159]
[PUBMED:15342917]
[PUBMED:11500364]
[PUBMED:19812304]
[PUBMED:12482958]
[PUBMED:11729323]
[PUBMED:16962653]
[PUBMED:18952604]
[PUBMED:9465032]
[PUBMED:1496022]
[PUBMED:10567431]
[PUBMED:19114562]
[PUBMED:17510057]
[PUBMED:18604198]
[PUBMED:15545625]
[PUBMED:11914378]
[PUBMED:17461779]
[PUBMED:9445476]
[PUBMED:18497260]
[PUBMED:12604610]
[PUBMED:15071500]
[PUBMED:18925875]
[PUBMED:12906785]
[PUBMED:11287630]
[PUBMED:15004009]
[PUBMED:16756488]
[PUBMED:17043309]
[PUBMED:18198340]
[PUBMED:12820960]
[PUBMED:12747827]
[PUBMED:17053147]
[PUBMED:15851026]
[PUBMED:15467718]
[PUBMED:18762023]
[PUBMED:25242279]
[PUBMED:24698685]
[PUBMED:11175345]
[PUBMED:27304501]
[PUBMED:18411301]
[PUBMED:11500365]
[PUBMED:17693255]
[PUBMED:23694989]
[PUBMED:12231510]
[PUBMED:19446321]
[PUBMED:11418588]
[PUBMED:19258318]
[PUBMED:18439900]
[PUBMED:19225151]
[PUBMED:26185979]
[PUBMED:10357815]
[PUBMED:26269525]
[PUBMED:23421405]
[PUBMED:9271440]
[PUBMED:16915281]
[PUBMED:17141160]
[PUBMED:15249583]
[PUBMED:12912989]
[PUBMED:27027448]
[PUBMED:18423201]
[PUBMED:19211835]
[PUBMED:9204908]
[PUBMED:26700098]
[PUBMED:18566587]
[PUBMED:17386266]