full name
T-cell lymphoma invasion and metastasis 2

synonyms
STEF, TIAM-2, TIAM2, ENSG00000146426

HGNC
HGNC:11806

Entrez Gene
Gene:26230

ENSEMBL
ENSG00000146426

location
chr: 6
start: 155316488
stop: 155578857
strand: +

transcripts
ENST00000318981.5
ENST00000275246.7

pathways
Cell death signalling via NRAGE, NRIF and NADE [NCBI:1269447] [REACTOME:R-HSA-204998] [PUBMED:12787561]
Fatty acid, triacylglycerol, and ketone body metabolism [NCBI:1270010] [REACTOME:R-HSA-535734]
G alpha (12/13) signalling events [NCBI:1269579] [REACTOME:R-HSA-416482] [PUBMED:18814923] [PUBMED:19212140]
GPCR downstream signaling [NCBI:1269574] [REACTOME:R-HSA-388396] [PUBMED:12040175]
Metabolism [NCBI:1269956] [REACTOME:R-HSA-1430728]
Metabolism of lipids and lipoproteins [NCBI:1270001] [REACTOME:R-HSA-556833]
NRAGE signals death through JNK [NCBI:1269448] [REACTOME:R-HSA-193648] [PUBMED:12376548]
PPARA activates gene expression [NCBI:1270030] [REACTOME:R-HSA-1989781] [PUBMED:10529898] [PUBMED:18288277] [PUBMED:11330046] [PUBMED:20936127] [PUBMED:14999402]
Regulation of RAC1 activity [NCBI:169346] [Pathway Interaction Database:rac1_reg_pathway] [PUBMED:8297393] [PUBMED:12134164] [PUBMED:15485841] [PUBMED:11707441] [PUBMED:17320046] [PUBMED:9857026] [PUBMED:9497316] [PUBMED:17254573] [PUBMED:15850775] [PUBMED:8352776] [PUBMED:15128856] [PUBMED:17403664] [PUBMED:8491184] [PUBMED:7753201] [PUBMED:9707409] [PUBMED:12432077] [PUBMED:8226937] [PUBMED:19934221] [PUBMED:17196961] [PUBMED:17640372] [PUBMED:11287617] [PUBMED:12515821] [PUBMED:16943182] [PUBMED:19861492] [PUBMED:10220378] [PUBMED:11431473] [PUBMED:10982832] [PUBMED:7673236] [PUBMED:10744696] [PUBMED:17599059] [PUBMED:17116687] [PUBMED:12923183] [PUBMED:10364228] [PUBMED:16628218] [PUBMED:8288572] [PUBMED:15306850] [PUBMED:11396949] [PUBMED:8496137] [PUBMED:11912491] [PUBMED:15649357] [PUBMED:7980444] [PUBMED:18325335] [PUBMED:15242348] [PUBMED:11955434] [PUBMED:15039778] [PUBMED:11685227] [PUBMED:15897194] [PUBMED:11130063] [PUBMED:10559863] [PUBMED:17052214] [PUBMED:11099046] [PUBMED:15728722] [PUBMED:16520382] [PUBMED:16492808] [PUBMED:12547822] [PUBMED:12446789] [PUBMED:11274357] [PUBMED:8419353] [PUBMED:16481401] [PUBMED:8276860] [PUBMED:15005707] [PUBMED:10499589] [PUBMED:11336673] [PUBMED:1903516] [PUBMED:12829596] [PUBMED:17332503] [PUBMED:11146652] [PUBMED:12134158] [PUBMED:8643598] [PUBMED:18212043]
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) [NCBI:1270029] [REACTOME:R-HSA-400206] [PUBMED:18288277] [PUBMED:10529898] [PUBMED:16476485] [PUBMED:16503871]
Rho GTPase cycle [NCBI:1269508] [REACTOME:R-HSA-194840] [PUBMED:17222083] [PUBMED:9308960]
Signal Transduction [NCBI:1269379] [REACTOME:R-HSA-162582] [PUBMED:17604717] [PUBMED:19648010] [PUBMED:16260143] [PUBMED:11742412] [PUBMED:19536106] [PUBMED:15863030] [PUBMED:19379690] [PUBMED:19458711] [PUBMED:19935667] [PUBMED:21252999] [PUBMED:15520807] [PUBMED:17496910] [PUBMED:15450248] [PUBMED:18043707] [PUBMED:16939974] [PUBMED:19762341] [PUBMED:18483217] [PUBMED:17084981] [PUBMED:21781017] [PUBMED:19619488]
Signaling by GPCR [NCBI:1269543] [REACTOME:R-HSA-372790] [PUBMED:16902930] [PUBMED:10202136] [PUBMED:18043707]
Signaling by Rho GTPases [NCBI:1269507] [REACTOME:R-HSA-194315] [PUBMED:16212495] [PUBMED:15630019]
Signalling by NGF [NCBI:1269443] [REACTOME:R-HSA-166520]
p75 NTR receptor-mediated signalling [NCBI:1269445] [REACTOME:R-HSA-193704] [PUBMED:16699811] [PUBMED:16939974] [PUBMED:12671646]