full name
superoxide dismutase 2

synonyms
IPOB, MNSOD, MVCD6, SOD2, ENSG00000112096

HGNC
HGNC:11180

Entrez Gene
Gene:6648

ENSEMBL
ENSG00000112096

location
chr: 6
start: 160100148
stop: 160114353
strand: -

OMIM
OMIM:147460: SOD2
OMIM:612634: {Microvascular complications of diabetes 6}

transcripts
NM_001024466.1
NM_001024465.1
NM_000636.2

pathways
Cellular responses to stress [NCBI:1270414] [REACTOME:R-HSA-2262752] [PUBMED:15709958]
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models [NCBI:1457789] [REACTOME:R-HSA-8862803] [PUBMED:8090221] [PUBMED:12684440] [PUBMED:22899714] [PUBMED:10830966] [PUBMED:7592934] [PUBMED:19519302]
Detoxification of Reactive Oxygen Species [NCBI:1270420] [REACTOME:R-HSA-3299685] [PUBMED:23469953] [PUBMED:23268465] [PUBMED:20064600] [PUBMED:22286106] [PUBMED:21473702] [PUBMED:22196163] [PUBMED:21375475] [PUBMED:19061483] [PUBMED:21453242]
Disease [NCBI:1268854] [REACTOME:R-HSA-1643685]
FoxO family signaling [NCBI:138036] [Pathway Interaction Database:foxopathway] [PUBMED:17038621] [PUBMED:15788402] [PUBMED:14976264] [PUBMED:11864996] [PUBMED:12517744] [PUBMED:11050388] [PUBMED:10960473] [PUBMED:10783894] [PUBMED:11154281] [PUBMED:11313479] [PUBMED:11777915] [PUBMED:11980723] [PUBMED:10102273] [PUBMED:15509806] [PUBMED:11237865] [PUBMED:16751106] [PUBMED:12857750] [PUBMED:15538382] [PUBMED:12239572] [PUBMED:12048180] [PUBMED:11884717] [PUBMED:11884591] [PUBMED:15084260] [PUBMED:11964479] [PUBMED:10217147] [PUBMED:15109499] [PUBMED:16964248] [PUBMED:15905404] [PUBMED:11607034] [PUBMED:15668399] [PUBMED:15220471] [PUBMED:10358075] [PUBMED:16424905]
FoxO signaling pathway [NCBI:921162] [KEGG:hsa04068] [PUBMED:23325358] [PUBMED:15005655] [PUBMED:18951090] [PUBMED:22761423] [PUBMED:22902436] [PUBMED:16288288] [PUBMED:19701188] [PUBMED:16964248] [PUBMED:18045156] [PUBMED:18403263] [PUBMED:21613825] [PUBMED:21440011] [PUBMED:17470511] [PUBMED:21238503] [PUBMED:17522590] [PUBMED:15084259] [PUBMED:23801966] [PUBMED:17569704] [PUBMED:15516968]
Huntington's disease [NCBI:83100] [KEGG:hsa05016] [PUBMED:15336977] [PUBMED:11738471] [PUBMED:11807533] [PUBMED:15996546] [PUBMED:14526190] [PUBMED:15242639] [PUBMED:17041811] [PUBMED:15996541] [PUBMED:18951640] [PUBMED:15459747] [PUBMED:16288298] [PUBMED:17081970] [PUBMED:15695335] [PUBMED:12372277] [PUBMED:11839795]
Longevity regulating pathway [NCBI:1319989] [KEGG:hsa04211] [PUBMED:21779512] [PUBMED:23594965] [PUBMED:25654554] [PUBMED:25832544] [PUBMED:24997879] [PUBMED:22618766] [PUBMED:20336132] [PUBMED:24905167] [PUBMED:25601466] [PUBMED:20103737] [PUBMED:18692468] [PUBMED:20395504] [PUBMED:25824609] [PUBMED:17701476] [PUBMED:23939249] [PUBMED:20848587] [PUBMED:22983298] [PUBMED:19262508] [PUBMED:20357764] [PUBMED:18946478] [PUBMED:23061800]
Longevity regulating pathway - multiple species [NCBI:1340713] [KEGG:hsa04213] [PUBMED:26682004] [PUBMED:20098959] [PUBMED:17684529] [PUBMED:14534077] [PUBMED:16304601] [PUBMED:17701476] [PUBMED:20395504] [PUBMED:18373439] [PUBMED:20336132] [PUBMED:21909281] [PUBMED:26525455] [PUBMED:22094419] [PUBMED:12610293] [PUBMED:15768047] [PUBMED:23615258] [PUBMED:18946478] [PUBMED:20097433] [PUBMED:21841070] [PUBMED:25153840]
Neurodegenerative Diseases [NCBI:1457788] [REACTOME:R-HSA-8863678] [PUBMED:26848654]
Peroxisome [NCBI:131226] [KEGG:hsa04146] [PUBMED:17055079] [PUBMED:16631601] [PUBMED:17055078] [PUBMED:17010456]
reactive oxygen species degradation [NCBI:1108784] [BIOCYC:HUMAN_DETOX1-PWY-1] [PUBMED:2853161] [PUBMED:11997379] [PUBMED:9214587] [PUBMED:10666617] [PUBMED:10638941] [PUBMED:9765550] [PUBMED:24511533]