full name
MAD1 mitotic arrest deficient like 1

synonyms
MAD1, PIG9, TP53I9, TXBP181, MAD1L1, ENSG00000002822

HGNC
HGNC:6762

Entrez Gene
Gene:8379

ENSEMBL
ENSG00000002822

location
chr: 7
start: 1855428
stop: 2272583
strand: -

OMIM
OMIM:602686: MAD1L1
OMIM:176807: Prostate cancer, somatic

transcripts
NM_001013837.1
NM_001013836.1
NM_003550.2

pathways
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal [NCBI:1269760] [REACTOME:R-HSA-141444] [PUBMED:14593737]
Amplification of signal from the kinetochores [NCBI:1269759] [REACTOME:R-HSA-141424] [PUBMED:14593737]
C-MYB transcription factor network [NCBI:138073] [Pathway Interaction Database:cmyb_pathway] [PUBMED:17152050] [PUBMED:1944282] [PUBMED:7964503] [PUBMED:8598284] [PUBMED:15608679] [PUBMED:10619021] [PUBMED:2233716] [PUBMED:9244354] [PUBMED:8654374] [PUBMED:10590070] [PUBMED:17587615] [PUBMED:12424255] [PUBMED:1679531] [PUBMED:17077080] [PUBMED:8946914] [PUBMED:16055116] [PUBMED:11259163] [PUBMED:9659917] [PUBMED:9135152] [PUBMED:7721782] [PUBMED:11290610] [PUBMED:12244173] [PUBMED:11792321] [PUBMED:17242210] [PUBMED:10722757] [PUBMED:8264615] [PUBMED:15687240] [PUBMED:14761981] [PUBMED:10542314] [PUBMED:12673198] [PUBMED:11779867] [PUBMED:8756344] [PUBMED:11427482] [PUBMED:9809063] [PUBMED:10523863] [PUBMED:11094072] [PUBMED:15356292] [PUBMED:11781241] [PUBMED:15778089] [PUBMED:9096387] [PUBMED:17931383] [PUBMED:14576818] [PUBMED:11259170] [PUBMED:8491193] [PUBMED:11581319] [PUBMED:10644988] [PUBMED:7565722] [PUBMED:9490676] [PUBMED:9244356] [PUBMED:17641686] [PUBMED:16407849] [PUBMED:1594249] [PUBMED:17822556] [PUBMED:15867358] [PUBMED:17959653] [PUBMED:7509358] [PUBMED:11287612] [PUBMED:15082531] [PUBMED:10766162] [PUBMED:8756629] [PUBMED:11115410] [PUBMED:7684005] [PUBMED:9566892]
Cell Cycle [NCBI:1269741] [REACTOME:R-HSA-1640170]
Cell Cycle Checkpoints [NCBI:1269742] [REACTOME:R-HSA-69620]
Cell Cycle, Mitotic [NCBI:1269763] [REACTOME:R-HSA-69278]
Cell cycle [NCBI:83054] [KEGG:hsa04110] [PUBMED:7973727] [PUBMED:17568790] [PUBMED:9832503] [PUBMED:16936746] [PUBMED:9029154] [PUBMED:12573239] [PUBMED:19020303] [PUBMED:9618481] [PUBMED:12809600] [PUBMED:8242749] [PUBMED:10385618] [PUBMED:17426725] [PUBMED:17018296] [PUBMED:16212951] [PUBMED:12925736] [PUBMED:11099028] [PUBMED:15568976] [PUBMED:15838516] [PUBMED:15838523] [PUBMED:15876871] [PUBMED:7908906] [PUBMED:9889196]
M Phase [NCBI:1269810] [REACTOME:R-HSA-68886]
Mitotic Anaphase [NCBI:1269825] [REACTOME:R-HSA-68882]
Mitotic Metaphase and Anaphase [NCBI:1269823] [REACTOME:R-HSA-2555396]
Mitotic Prometaphase [NCBI:1269820] [REACTOME:R-HSA-68877]
Mitotic Spindle Checkpoint [NCBI:1269758] [REACTOME:R-HSA-69618] [PUBMED:14593737] [PUBMED:12360190]
Progesterone-mediated oocyte maturation [NCBI:119304] [KEGG:hsa04914] [PUBMED:10497333] [PUBMED:12084906] [PUBMED:12045215] [PUBMED:11063930] [PUBMED:12477927] [PUBMED:11148128] [PUBMED:11730319] [PUBMED:12374568]
RHO GTPase Effectors [NCBI:1269509] [REACTOME:R-HSA-195258] [PUBMED:9694656] [PUBMED:18066052] [PUBMED:11018042] [PUBMED:10470034] [PUBMED:8702756] [PUBMED:21730051] [PUBMED:8571126] [PUBMED:19513348] [PUBMED:17244649] [PUBMED:11145705] [PUBMED:24128008] [PUBMED:23716662] [PUBMED:8617235] [PUBMED:8543060] [PUBMED:11804587] [PUBMED:24969695] [PUBMED:12635176] [PUBMED:12778124] [PUBMED:18006505] [PUBMED:1660188] [PUBMED:21351730] [PUBMED:16507994] [PUBMED:14595335] [PUBMED:10072071] [PUBMED:10591629] [PUBMED:10753910] [PUBMED:23875749] [PUBMED:17151359] [PUBMED:10652353] [PUBMED:12221077] [PUBMED:10559936] [PUBMED:12783890] [PUBMED:11948177] [PUBMED:18237546] [PUBMED:16079795] [PUBMED:10924361] [PUBMED:14514689] [PUBMED:8107774] [PUBMED:8756646] [PUBMED:16979770] [PUBMED:16636067] [PUBMED:9751706] [PUBMED:10619026] [PUBMED:23444367] [PUBMED:15546864] [PUBMED:12473120] [PUBMED:8816443] [PUBMED:9199170] [PUBMED:12514133] [PUBMED:16762923] [PUBMED:12110184] [PUBMED:16431929] [PUBMED:10975528] [PUBMED:10940294] [PUBMED:9535855] [PUBMED:7559638] [PUBMED:11162552] [PUBMED:19737400] [PUBMED:9988689] [PUBMED:12732141] [PUBMED:8798539] [PUBMED:24914801] [PUBMED:11689693] [PUBMED:8769096] [PUBMED:9368021]
RHO GTPases Activate Formins [NCBI:1269519] [REACTOME:R-HSA-5663220] [PUBMED:20233848] [PUBMED:15507212] [PUBMED:16292343] [PUBMED:12906795] [PUBMED:11779461] [PUBMED:21397845] [PUBMED:12577064] [PUBMED:17198702] [PUBMED:15006353] [PUBMED:20101212] [PUBMED:15944396] [PUBMED:10678165] [PUBMED:16943183] [PUBMED:16439214] [PUBMED:16472745] [PUBMED:10958683] [PUBMED:12732141] [PUBMED:15085137] [PUBMED:24914801] [PUBMED:9497258] [PUBMED:21576392] [PUBMED:21868368]
Resolution of Sister Chromatid Cohesion [NCBI:1269821] [REACTOME:R-HSA-2500257] [PUBMED:16541025] [PUBMED:15339662] [PUBMED:17112726] [PUBMED:9649503] [PUBMED:21111234] [PUBMED:15737063] [PUBMED:17113138] [PUBMED:21987589] [PUBMED:14730319] [PUBMED:11509732] [PUBMED:19696148] [PUBMED:21878504] [PUBMED:15723797]
Separation of Sister Chromatids [NCBI:1269826] [REACTOME:R-HSA-2467813] [PUBMED:11081627] [PUBMED:10411507] [PUBMED:12070128] [PUBMED:12194817] [PUBMED:11509732]
Signal Transduction [NCBI:1269379] [REACTOME:R-HSA-162582] [PUBMED:17604717] [PUBMED:19648010] [PUBMED:16260143] [PUBMED:11742412] [PUBMED:19536106] [PUBMED:15863030] [PUBMED:19379690] [PUBMED:19458711] [PUBMED:19935667] [PUBMED:21252999] [PUBMED:15520807] [PUBMED:17496910] [PUBMED:15450248] [PUBMED:18043707] [PUBMED:16939974] [PUBMED:19762341] [PUBMED:18483217] [PUBMED:17084981] [PUBMED:21781017] [PUBMED:19619488]
Signaling by Rho GTPases [NCBI:1269507] [REACTOME:R-HSA-194315] [PUBMED:16212495] [PUBMED:15630019]
Viral carcinogenesis [NCBI:658418] [KEGG:hsa05203] [PUBMED:9990017] [PUBMED:15173177] [PUBMED:16036567] [PUBMED:16581947] [PUBMED:9060639] [PUBMED:17457345] [PUBMED:15956361] [PUBMED:21421561] [PUBMED:18391203] [PUBMED:21040832] [PUBMED:9837909] [PUBMED:17645777] [PUBMED:15967719] [PUBMED:12686421] [PUBMED:17049016] [PUBMED:21152115] [PUBMED:11160754] [PUBMED:21966251] [PUBMED:17979705] [PUBMED:8617242] [PUBMED:12925958] [PUBMED:10873631] [PUBMED:21250384] [PUBMED:15614436] [PUBMED:10354594] [PUBMED:20494113] [PUBMED:18702816] [PUBMED:9651361] [PUBMED:16459163] [PUBMED:11278402] [PUBMED:15510157] [PUBMED:19956178] [PUBMED:18251977] [PUBMED:11766888] [PUBMED:10824878] [PUBMED:21372216] [PUBMED:11244044] [PUBMED:17894800] [PUBMED:11905817] [PUBMED:21347341] [PUBMED:12186904] [PUBMED:9374493] [PUBMED:16352731] [PUBMED:12770701] [PUBMED:17384582] [PUBMED:14506283] [PUBMED:11091847] [PUBMED:17267064] [PUBMED:11886269] [PUBMED:21177815] [PUBMED:10400746] [PUBMED:19156753] [PUBMED:9882379] [PUBMED:14559998] [PUBMED:15767449] [PUBMED:22110506] [PUBMED:20534855] [PUBMED:15542638] [PUBMED:9343405] [PUBMED:10405893] [PUBMED:19400863] [PUBMED:9349482] [PUBMED:14747563] [PUBMED:21647825] [PUBMED:12970441] [PUBMED:11669605] [PUBMED:15795286] [PUBMED:21994562] [PUBMED:14530271] [PUBMED:9594662] [PUBMED:22566809] [PUBMED:19651473] [PUBMED:8756622] [PUBMED:15105524] [PUBMED:15452270] [PUBMED:18948197] [PUBMED:16760382] [PUBMED:10793105] [PUBMED:21084867] [PUBMED:16308315] [PUBMED:16155604] [PUBMED:16381817] [PUBMED:16828973] [PUBMED:15342967] [PUBMED:15692053] [PUBMED:10855768] [PUBMED:19078975] [PUBMED:12379483] [PUBMED:15310405] [PUBMED:8223437] [PUBMED:16939421] [PUBMED:12910250] [PUBMED:16039586] [PUBMED:18201576] [PUBMED:21102637] [PUBMED:21743832] [PUBMED:20592731] [PUBMED:10644344] [PUBMED:10074132] [PUBMED:19715458] [PUBMED:16155601] [PUBMED:11604508] [PUBMED:15919895] [PUBMED:11099494] [PUBMED:18385245] [PUBMED:19854353] [PUBMED:12101418]