full name
interleukin 6
synonyms
BSF2, HGF, HSF, IFNB2, IL-6, IL6, ENSG00000136244
HGNC
HGNC:6018
Entrez Gene
Gene:3569
ENSEMBL
ENSG00000136244
location
chr: 7
start: 22766766
stop: 22771621
strand: +
OMIM
OMIM:147620:
IL6
OMIM:266600:
{Crohn disease-associated growth failure}
OMIM:125853:
{Diabetes, susceptibility to}, 222100
OMIM:108010:
{Intracranial hemorrhage in brain cerebrovascular malformations, susceptibility to}
OMIM:148000:
{Kaposi sarcoma, susceptibility to}
OMIM:604302:
{Rheumatoid arthritis, systemic juvenile}
transcripts
NM_000600.3
pathways
AGE-RAGE signaling pathway in diabetic complications
[NCBI:1319988]
[KEGG:hsa04933]
[PUBMED:23776698]
[PUBMED:15569303]
[PUBMED:16894049]
[PUBMED:18323529]
[PUBMED:11375353]
[PUBMED:21111800]
[PUBMED:19404313]
[PUBMED:20470857]
[PUBMED:17005604]
[PUBMED:23961320]
[PUBMED:21261520]
[PUBMED:11180401]
[PUBMED:18922799]
[PUBMED:21680901]
[PUBMED:11684565]
[PUBMED:21590515]
[PUBMED:12709399]
[PUBMED:20300563]
[PUBMED:21440603]
[PUBMED:22558488]
ATF-2 transcription factor network
[NCBI:138006]
[Pathway Interaction Database:atf2_pathway]
[PUBMED:12048217]
[PUBMED:19255142]
[PUBMED:11739785]
[PUBMED:7624151]
[PUBMED:19822663]
[PUBMED:17590016]
[PUBMED:7535770]
[PUBMED:18396163]
[PUBMED:20507983]
[PUBMED:19422799]
[PUBMED:7824938]
[PUBMED:11713276]
[PUBMED:17258390]
[PUBMED:10454570]
[PUBMED:20067572]
[PUBMED:10364225]
[PUBMED:12121977]
[PUBMED:12110590]
[PUBMED:19176525]
[PUBMED:16511568]
[PUBMED:17079470]
[PUBMED:17267404]
[PUBMED:10777595]
[PUBMED:2516827]
[PUBMED:18397884]
[PUBMED:10207054]
[PUBMED:9436983]
[PUBMED:7737130]
[PUBMED:10982836]
[PUBMED:9006914]
[PUBMED:19592489]
[PUBMED:17158955]
[PUBMED:17189429]
[PUBMED:11566021]
[PUBMED:17626013]
[PUBMED:17036053]
[PUBMED:20702711]
[PUBMED:10085140]
[PUBMED:20032511]
[PUBMED:17219413]
[PUBMED:17337306]
[PUBMED:9511728]
[PUBMED:12196528]
[PUBMED:19304750]
[PUBMED:17700520]
[PUBMED:16373341]
[PUBMED:12833146]
[PUBMED:1827203]
[PUBMED:17699753]
[PUBMED:9990041]
[PUBMED:15304344]
[PUBMED:11231009]
[PUBMED:18385943]
[PUBMED:18387947]
[PUBMED:18638549]
[PUBMED:15767263]
[PUBMED:10777545]
[PUBMED:14630918]
[PUBMED:18802055]
[PUBMED:10037779]
[PUBMED:12052888]
[PUBMED:8943243]
[PUBMED:20181929]
[PUBMED:19647037]
[PUBMED:8382609]
[PUBMED:16405968]
[PUBMED:1641004]
African trypanosomiasis
[NCBI:194384]
[KEGG:hsa05143]
[PUBMED:9574925]
[PUBMED:12088284]
[PUBMED:19559585]
[PUBMED:20398209]
[PUBMED:17582444]
[PUBMED:19168735]
[PUBMED:19016378]
[PUBMED:11850009]
[PUBMED:16600243]
[PUBMED:19995590]
[PUBMED:19621073]
Amoebiasis
[NCBI:167324]
[KEGG:hsa05146]
[PUBMED:9832261]
[PUBMED:16380324]
[PUBMED:14700586]
[PUBMED:18725798]
[PUBMED:12142490]
[PUBMED:10637584]
[PUBMED:20145703]
[PUBMED:11378035]
[PUBMED:12160867]
[PUBMED:15813717]
[PUBMED:19207103]
[PUBMED:12660071]
[PUBMED:20303955]
[PUBMED:11352795]
[PUBMED:14502002]
[PUBMED:10756002]
[PUBMED:17702556]
[PUBMED:17576362]
Antifolate resistance
[NCBI:1440526]
[KEGG:hsa01523]
[PUBMED:17333344]
[PUBMED:23987246]
[PUBMED:11509639]
[PUBMED:24732946]
[PUBMED:8793930]
[PUBMED:15117425]
[PUBMED:22921318]
[PUBMED:16491071]
[PUBMED:26920997]
[PUBMED:22954694]
[PUBMED:17092765]
[PUBMED:17203006]
[PUBMED:23897011]
[PUBMED:21317831]
[PUBMED:18297517]
[PUBMED:14576850]
[PUBMED:16380836]
Cellular Senescence
[NCBI:1270426]
[REACTOME:R-HSA-2559583]
[PUBMED:21078816]
[PUBMED:18711403]
[PUBMED:22048312]
[PUBMED:19818705]
[PUBMED:17662938]
[PUBMED:23746838]
[PUBMED:9282108]
[PUBMED:17667954]
[PUBMED:13905658]
Cellular responses to stress
[NCBI:1270414]
[REACTOME:R-HSA-2262752]
[PUBMED:15709958]
Chagas disease (American trypanosomiasis)
[NCBI:147809]
[KEGG:hsa05142]
[PUBMED:12377585]
[PUBMED:9794425]
[PUBMED:1717552]
[PUBMED:16238097]
[PUBMED:10066513]
[PUBMED:12874238]
[PUBMED:12036740]
[PUBMED:15917295]
[PUBMED:12055254]
[PUBMED:17651955]
[PUBMED:1396957]
[PUBMED:16175174]
[PUBMED:2194668]
[PUBMED:9190942]
[PUBMED:12377942]
[PUBMED:12427093]
[PUBMED:10234174]
[PUBMED:16030288]
[PUBMED:15223603]
[PUBMED:17110955]
Cytokine Signaling in Immune system
[NCBI:1269310]
[REACTOME:R-HSA-1280215]
[PUBMED:12613569]
Cytokine-cytokine receptor interaction
[NCBI:83051]
[KEGG:hsa04060]
[PUBMED:11071910]
[PUBMED:12072446]
[PUBMED:7791754]
[PUBMED:15032600]
[PUBMED:12651226]
[PUBMED:11252892]
[PUBMED:11796220]
[PUBMED:11312110]
[PUBMED:9862719]
[PUBMED:12421671]
[PUBMED:12039028]
[PUBMED:9759503]
[PUBMED:9395284]
[PUBMED:11166270]
[PUBMED:10714678]
[PUBMED:12651221]
Cytosolic DNA-sensing pathway
[NCBI:125137]
[KEGG:hsa04623]
[PUBMED:18573338]
[PUBMED:19665965]
[PUBMED:19567913]
[PUBMED:18280611]
[PUBMED:18724932]
[PUBMED:19497760]
[PUBMED:16286919]
[PUBMED:19122387]
[PUBMED:19590578]
[PUBMED:23258413]
[PUBMED:18375758]
[PUBMED:19321146]
[PUBMED:19362700]
[PUBMED:18941233]
[PUBMED:19767723]
EGFR tyrosine kinase inhibitor resistance
[NCBI:1404798]
[KEGG:hsa01521]
[PUBMED:16843264]
[PUBMED:23401451]
[PUBMED:20966921]
[PUBMED:24307395]
[PUBMED:22956644]
[PUBMED:25232485]
[PUBMED:24493829]
[PUBMED:23071030]
[PUBMED:18483355]
[PUBMED:24202392]
[PUBMED:19632948]
[PUBMED:23361103]
[PUBMED:26579470]
[PUBMED:22970367]
[PUBMED:23358468]
[PUBMED:17554333]
[PUBMED:25337673]
[PUBMED:22474259]
[PUBMED:20551942]
FoxO signaling pathway
[NCBI:921162]
[KEGG:hsa04068]
[PUBMED:23325358]
[PUBMED:15005655]
[PUBMED:18951090]
[PUBMED:22761423]
[PUBMED:22902436]
[PUBMED:16288288]
[PUBMED:19701188]
[PUBMED:16964248]
[PUBMED:18045156]
[PUBMED:18403263]
[PUBMED:21613825]
[PUBMED:21440011]
[PUBMED:17470511]
[PUBMED:21238503]
[PUBMED:17522590]
[PUBMED:15084259]
[PUBMED:23801966]
[PUBMED:17569704]
[PUBMED:15516968]
Glucocorticoid receptor regulatory network
[NCBI:138014]
[Pathway Interaction Database:reg_gr_pathway]
[PUBMED:8943293]
[PUBMED:1708774]
[PUBMED:15826950]
[PUBMED:11027313]
[PUBMED:12118039]
[PUBMED:9388207]
[PUBMED:11751894]
[PUBMED:12151000]
[PUBMED:9765258]
[PUBMED:9407028]
[PUBMED:19074285]
[PUBMED:2838908]
[PUBMED:15817653]
[PUBMED:9722596]
[PUBMED:12917342]
[PUBMED:1387550]
[PUBMED:10974006]
[PUBMED:15790729]
[PUBMED:10825196]
[PUBMED:10623828]
[PUBMED:2169352]
[PUBMED:9315653]
[PUBMED:7759501]
[PUBMED:8290595]
[PUBMED:2905764]
[PUBMED:12351702]
[PUBMED:11080152]
[PUBMED:8428574]
[PUBMED:9215863]
[PUBMED:15459252]
[PUBMED:10400612]
[PUBMED:9426156]
[PUBMED:17440046]
[PUBMED:18838540]
[PUBMED:2169353]
[PUBMED:10820245]
[PUBMED:12511605]
[PUBMED:2586521]
[PUBMED:1740658]
[PUBMED:11555652]
[PUBMED:11562347]
[PUBMED:9482836]
[PUBMED:18337589]
[PUBMED:10958685]
[PUBMED:9388192]
[PUBMED:15834420]
[PUBMED:15657031]
[PUBMED:8878484]
[PUBMED:10760263]
[PUBMED:12730237]
[PUBMED:8702844]
[PUBMED:2169351]
[PUBMED:17215482]
[PUBMED:8898375]
Graft-versus-host disease
[NCBI:83124]
[KEGG:hsa05332]
[PUBMED:14556773]
[PUBMED:17784964]
[PUBMED:14735553]
[PUBMED:16412784]
[PUBMED:17900507]
[PUBMED:15372473]
[PUBMED:16147539]
[PUBMED:12359826]
[PUBMED:15882431]
HIF-1 signaling pathway
[NCBI:695200]
[KEGG:hsa04066]
[PUBMED:11902584]
[PUBMED:20965423]
[PUBMED:20679415]
[PUBMED:15031665]
[PUBMED:18259201]
[PUBMED:22205687]
[PUBMED:19364912]
[PUBMED:19147540]
[PUBMED:15448722]
[PUBMED:16234508]
[PUBMED:18505681]
[PUBMED:20836033]
[PUBMED:19861159]
[PUBMED:17955264]
[PUBMED:22562152]
HTLV-I infection
[NCBI:373901]
[KEGG:hsa05166]
[PUBMED:17446673]
[PUBMED:16436385]
[PUBMED:14686485]
[PUBMED:19861996]
[PUBMED:19092975]
[PUBMED:11325603]
[PUBMED:16155602]
[PUBMED:12910251]
[PUBMED:16155605]
[PUBMED:16036567]
[PUBMED:11244044]
[PUBMED:18702816]
[PUBMED:15569630]
[PUBMED:21114861]
[PUBMED:16155611]
[PUBMED:17384582]
[PUBMED:16155608]
[PUBMED:10602469]
[PUBMED:19014483]
[PUBMED:9325311]
Hematopoietic cell lineage
[NCBI:83078]
[KEGG:hsa04640]
[PUBMED:15629410]
[PUBMED:15738953]
[PUBMED:11905810]
[PUBMED:15156179]
[PUBMED:12415312]
[PUBMED:14985712]
[PUBMED:9927518]
[PUBMED:15771582]
[PUBMED:14670296]
[PUBMED:12360214]
Hepatitis B
[NCBI:694606]
[KEGG:hsa05161]
[PUBMED:19854353]
[PUBMED:11604508]
[PUBMED:11325602]
[PUBMED:18931690]
[PUBMED:16891440]
[PUBMED:17158882]
[PUBMED:11099494]
[PUBMED:9325306]
[PUBMED:18024894]
[PUBMED:11483993]
[PUBMED:15107488]
[PUBMED:11278872]
[PUBMED:21647825]
[PUBMED:11287574]
[PUBMED:18481805]
[PUBMED:17188775]
[PUBMED:19784739]
[PUBMED:19263472]
[PUBMED:16203685]
[PUBMED:18605975]
[PUBMED:10454581]
[PUBMED:22504921]
[PUBMED:21334391]
[PUBMED:20657822]
[PUBMED:18046710]
[PUBMED:9843511]
[PUBMED:15542625]
[PUBMED:21618535]
[PUBMED:15132991]
[PUBMED:15173177]
[PUBMED:12771941]
[PUBMED:21994545]
[PUBMED:8764004]
[PUBMED:16459163]
[PUBMED:9738022]
[PUBMED:11821950]
[PUBMED:12839924]
Herpes simplex infection
[NCBI:377873]
[KEGG:hsa05168]
[PUBMED:12224518]
[PUBMED:17913820]
[PUBMED:12844494]
[PUBMED:10998601]
[PUBMED:15163721]
[PUBMED:19694546]
[PUBMED:16297150]
[PUBMED:14747533]
[PUBMED:12826401]
[PUBMED:14963113]
[PUBMED:15056211]
[PUBMED:12797447]
[PUBMED:21107701]
[PUBMED:10918307]
[PUBMED:10696424]
[PUBMED:16076403]
[PUBMED:10364308]
[PUBMED:17222692]
[PUBMED:9621021]
[PUBMED:12224508]
[PUBMED:19879619]
[PUBMED:11070032]
[PUBMED:9499021]
[PUBMED:18596690]
[PUBMED:12525427]
[PUBMED:12224517]
[PUBMED:10196275]
[PUBMED:15047834]
[PUBMED:18508584]
[PUBMED:20036979]
Hypertrophic cardiomyopathy (HCM)
[NCBI:114229]
[KEGG:hsa05410]
[PUBMED:11805847]
[PUBMED:18572189]
[PUBMED:14711353]
[PUBMED:19136482]
[PUBMED:18056765]
[PUBMED:11225594]
[PUBMED:12844200]
[PUBMED:10615904]
[PUBMED:11716909]
[PUBMED:11371514]
[PUBMED:12270949]
IL-17 signaling pathway
[NCBI:1474301]
[KEGG:hsa04657]
[PUBMED:17921324]
[PUBMED:24011563]
[PUBMED:21349428]
[PUBMED:20383173]
[PUBMED:20514051]
[PUBMED:20177959]
[PUBMED:18178098]
[PUBMED:21074482]
[PUBMED:21130872]
[PUBMED:17027518]
[PUBMED:23917206]
[PUBMED:23116200]
[PUBMED:18701318]
[PUBMED:26252407]
[PUBMED:22851696]
[PUBMED:21155836]
[PUBMED:25145755]
[PUBMED:17177681]
[PUBMED:19575028]
[PUBMED:23557798]
[PUBMED:21852080]
[PUBMED:22324470]
IL23-mediated signaling events
[NCBI:138000]
[Pathway Interaction Database:il23pathway]
[PUBMED:16200068]
[PUBMED:12023338]
[PUBMED:17030949]
[PUBMED:16670770]
[PUBMED:17074928]
[PUBMED:15583831]
[PUBMED:16919486]
[PUBMED:12417590]
[PUBMED:16622035]
[PUBMED:16698929]
[PUBMED:14978083]
[PUBMED:12610626]
[PUBMED:15308705]
[PUBMED:16200070]
[PUBMED:15657292]
[PUBMED:16648837]
[PUBMED:11114383]
[PUBMED:12023369]
[PUBMED:9038232]
IL27-mediated signaling events
[NCBI:137929]
[Pathway Interaction Database:il27pathway]
[PUBMED:11672539]
[PUBMED:16365415]
[PUBMED:16906167]
[PUBMED:15356135]
[PUBMED:14657353]
[PUBMED:15944269]
[PUBMED:14764690]
[PUBMED:14614852]
[PUBMED:15308705]
[PUBMED:15004160]
[PUBMED:12734330]
[PUBMED:11057672]
[PUBMED:15494513]
[PUBMED:14614853]
[PUBMED:12121660]
[PUBMED:16906166]
[PUBMED:15749890]
IL6-mediated signaling events
[NCBI:137932]
[Pathway Interaction Database:il6_7pathway]
[PUBMED:8559663]
[PUBMED:8662591]
[PUBMED:11689697]
[PUBMED:11727828]
[PUBMED:10383440]
[PUBMED:10777583]
[PUBMED:16774741]
[PUBMED:12754507]
[PUBMED:9295319]
[PUBMED:15722452]
[PUBMED:10859312]
[PUBMED:9590172]
[PUBMED:9880505]
[PUBMED:12445202]
[PUBMED:8134389]
[PUBMED:10409724]
[PUBMED:8164674]
[PUBMED:8272872]
[PUBMED:9794795]
[PUBMED:7678052]
[PUBMED:8511589]
[PUBMED:8668165]
[PUBMED:9724754]
[PUBMED:8083235]
[PUBMED:12754505]
[PUBMED:8621622]
[PUBMED:16254248]
[PUBMED:12361954]
[PUBMED:10605021]
[PUBMED:9388184]
[PUBMED:15935617]
[PUBMED:11120832]
[PUBMED:7875298]
[PUBMED:9973404]
[PUBMED:11335711]
[PUBMED:9632795]
[PUBMED:11468294]
[PUBMED:7898939]
[PUBMED:8626374]
[PUBMED:8670868]
[PUBMED:7537214]
[PUBMED:15677447]
[PUBMED:2261637]
[PUBMED:9874564]
[PUBMED:12829785]
[PUBMED:8537375]
[PUBMED:8272873]
[PUBMED:7523403]
[PUBMED:11251120]
[PUBMED:9163525]
[PUBMED:3136546]
[PUBMED:10727406]
[PUBMED:10023775]
[PUBMED:12754506]
[PUBMED:12456685]
[PUBMED:2788034]
[PUBMED:10446219]
[PUBMED:15572665]
[PUBMED:1662392]
[PUBMED:15010462]
[PUBMED:8140422]
[PUBMED:8467812]
Immune System
[NCBI:1269170]
[REACTOME:R-HSA-168256]
Inflammatory bowel disease (IBD)
[NCBI:842771]
[KEGG:hsa05321]
[PUBMED:17499605]
[PUBMED:12006974]
[PUBMED:18053739]
[PUBMED:20134493]
[PUBMED:10898785]
[PUBMED:18563156]
[PUBMED:23176791]
[PUBMED:18200661]
[PUBMED:12797537]
[PUBMED:21487504]
[PUBMED:19381306]
[PUBMED:21681604]
[PUBMED:19322214]
[PUBMED:16493424]
[PUBMED:18242222]
[PUBMED:12042806]
[PUBMED:9759857]
Influenza A
[NCBI:217173]
[KEGG:hsa05164]
[PUBMED:17267598]
[PUBMED:18049471]
[PUBMED:16882036]
[PUBMED:11907320]
[PUBMED:17944269]
[PUBMED:20629046]
[PUBMED:17072332]
[PUBMED:18588994]
[PUBMED:19864182]
[PUBMED:19290913]
[PUBMED:19420020]
[PUBMED:17213831]
[PUBMED:9060654]
[PUBMED:19481124]
[PUBMED:16494716]
[PUBMED:21147034]
[PUBMED:18980544]
[PUBMED:20020828]
[PUBMED:15502848]
[PUBMED:19782761]
Insulin resistance
[NCBI:1272486]
[KEGG:hsa04931]
[PUBMED:17130651]
[PUBMED:20466550]
[PUBMED:16364488]
[PUBMED:12765939]
[PUBMED:15166380]
[PUBMED:7666792]
[PUBMED:16756496]
[PUBMED:23647930]
[PUBMED:10923637]
[PUBMED:17141630]
[PUBMED:9886945]
[PUBMED:8048519]
[PUBMED:18309108]
[PUBMED:15107844]
[PUBMED:20526383]
[PUBMED:22360800]
[PUBMED:16186396]
[PUBMED:22675355]
[PUBMED:22677645]
Interleukin-10 signaling
[NCBI:1470924]
[REACTOME:R-HSA-6783783]
[PUBMED:11244051]
Interleukin-4 and 13 signaling
[NCBI:1470923]
[REACTOME:R-HSA-6785807]
[PUBMED:12704343]
[PUBMED:10358772]
Interleukin-6 family signaling
[NCBI:1339142]
[REACTOME:R-HSA-6783589]
[PUBMED:9685167]
[PUBMED:8666978]
[PUBMED:12773095]
[PUBMED:9143707]
[PUBMED:9716487]
[PUBMED:7632928]
Interleukin-6 signaling
[NCBI:1269325]
[REACTOME:R-HSA-1059683]
[PUBMED:20410258]
Intestinal immune network for IgA production
[NCBI:128760]
[KEGG:hsa04672]
[PUBMED:18483500]
[PUBMED:18838301]
[PUBMED:15971106]
[PUBMED:18243016]
[PUBMED:19079167]
[PUBMED:18549797]
[PUBMED:19079156]
[PUBMED:17161619]
[PUBMED:17182536]
[PUBMED:12511876]
Jak-STAT signaling pathway
[NCBI:83077]
[KEGG:hsa04630]
[PUBMED:21034406]
[PUBMED:22339650]
[PUBMED:16204702]
[PUBMED:25587654]
[PUBMED:24069565]
[PUBMED:22383755]
[PUBMED:24606160]
[PUBMED:10851053]
[PUBMED:23735217]
[PUBMED:25217450]
[PUBMED:21372217]
LPA receptor mediated events
[NCBI:137928]
[Pathway Interaction Database:lysophospholipid_pathway]
[PUBMED:10601262]
[PUBMED:16289596]
[PUBMED:7809106]
[PUBMED:10342794]
[PUBMED:15928312]
[PUBMED:16769764]
[PUBMED:11243883]
[PUBMED:14688263]
[PUBMED:10551845]
[PUBMED:16687414]
[PUBMED:9819398]
[PUBMED:7527052]
[PUBMED:9600933]
[PUBMED:2551506]
[PUBMED:15988003]
[PUBMED:10644509]
[PUBMED:16199135]
[PUBMED:15728708]
[PUBMED:1637305]
[PUBMED:7476905]
[PUBMED:7510708]
[PUBMED:8647803]
[PUBMED:10420989]
[PUBMED:12880866]
[PUBMED:10766839]
[PUBMED:12181443]
[PUBMED:15461590]
[PUBMED:16452634]
[PUBMED:16197369]
[PUBMED:10779388]
[PUBMED:10506190]
[PUBMED:9305878]
[PUBMED:16904289]
[PUBMED:15878967]
[PUBMED:15143197]
[PUBMED:11948806]
[PUBMED:11040035]
[PUBMED:12393875]
[PUBMED:9407095]
[PUBMED:15280372]
[PUBMED:16890224]
[PUBMED:8805276]
Legionellosis
[NCBI:469200]
[KEGG:hsa05134]
[PUBMED:19021631]
[PUBMED:19157961]
[PUBMED:20375353]
[PUBMED:19478083]
[PUBMED:18284575]
[PUBMED:19386084]
[PUBMED:19666608]
[PUBMED:15972519]
[PUBMED:18549456]
[PUBMED:1721820]
[PUBMED:17124169]
[PUBMED:19687203]
[PUBMED:18363881]
[PUBMED:19343209]
[PUBMED:20941588]
[PUBMED:16824952]
[PUBMED:18281405]
[PUBMED:18048909]
[PUBMED:16495539]
[PUBMED:12427954]
MAPK family signaling cascades
[NCBI:1269501]
[REACTOME:R-HSA-5683057]
[PUBMED:21167873]
[PUBMED:17161475]
[PUBMED:22535895]
[PUBMED:21372320]
MAPK1 (ERK2) activation
[NCBI:1269505]
[REACTOME:R-HSA-112411]
[PUBMED:22177953]
[PUBMED:8131746]
MAPK1/MAPK3 signaling
[NCBI:1269502]
[REACTOME:R-HSA-5684996]
[PUBMED:25378393]
[PUBMED:18199641]
[PUBMED:17496909]
[PUBMED:21779496]
[PUBMED:15520807]
[PUBMED:16393692]
[PUBMED:19520853]
[PUBMED:17496910]
[PUBMED:22569528]
MAPK3 (ERK1) activation
[NCBI:1269504]
[REACTOME:R-HSA-110056]
Malaria
[NCBI:152665]
[KEGG:hsa05144]
[PUBMED:15106591]
[PUBMED:11224682]
[PUBMED:17630968]
[PUBMED:18250459]
[PUBMED:16138104]
[PUBMED:20091081]
[PUBMED:8920859]
[PUBMED:19101208]
[PUBMED:16019257]
[PUBMED:15464448]
[PUBMED:11832955]
[PUBMED:12364790]
[PUBMED:10885986]
[PUBMED:15094163]
[PUBMED:14737184]
[PUBMED:15463497]
[PUBMED:16468982]
[PUBMED:19967139]
Measles
[NCBI:213306]
[KEGG:hsa05162]
[PUBMED:16237742]
[PUBMED:12804771]
[PUBMED:19198562]
[PUBMED:20376484]
[PUBMED:11385511]
[PUBMED:16963735]
[PUBMED:19198566]
[PUBMED:18922877]
[PUBMED:19203114]
[PUBMED:12620806]
[PUBMED:16690907]
[PUBMED:17720800]
[PUBMED:20636817]
[PUBMED:12410527]
[PUBMED:11582511]
[PUBMED:19203109]
[PUBMED:19203113]
[PUBMED:14585342]
[PUBMED:12805463]
NOD-like receptor signaling pathway
[NCBI:122191]
[KEGG:hsa04621]
[PUBMED:25330206]
[PUBMED:21575908]
[PUBMED:23846113]
[PUBMED:26549800]
[PUBMED:16493424]
[PUBMED:23124073]
[PUBMED:24840700]
[PUBMED:27291964]
[PUBMED:27012466]
[PUBMED:24707857]
[PUBMED:19767725]
[PUBMED:25879280]
[PUBMED:23215645]
[PUBMED:22819539]
[PUBMED:23702978]
[PUBMED:20643110]
[PUBMED:25879288]
[PUBMED:26655628]
[PUBMED:25145756]
[PUBMED:24718315]
[PUBMED:26482951]
[PUBMED:25526305]
[PUBMED:26121197]
[PUBMED:22430786]
Non-alcoholic fatty liver disease (NAFLD)
[NCBI:862188]
[KEGG:hsa04932]
[PUBMED:21038418]
[PUBMED:17498512]
[PUBMED:19352614]
[PUBMED:23299992]
[PUBMED:22570745]
[PUBMED:9285483]
[PUBMED:12891546]
[PUBMED:18061659]
[PUBMED:22705006]
[PUBMED:16364488]
[PUBMED:18242193]
[PUBMED:16374858]
[PUBMED:22940046]
[PUBMED:20619513]
[PUBMED:20303879]
[PUBMED:14685853]
[PUBMED:16406828]
[PUBMED:23545492]
[PUBMED:21145844]
PI3K-Akt signaling pathway
[NCBI:692234]
[KEGG:hsa04151]
[PUBMED:12048182]
[PUBMED:11357143]
[PUBMED:21440011]
[PUBMED:15209374]
[PUBMED:12669022]
[PUBMED:18842113]
[PUBMED:16847462]
[PUBMED:12660731]
[PUBMED:17360849]
[PUBMED:9838078]
[PUBMED:15505410]
[PUBMED:16248975]
[PUBMED:12531180]
[PUBMED:21779440]
[PUBMED:16187290]
[PUBMED:15784165]
[PUBMED:21620960]
Pathways in cancer
[NCBI:83105]
[KEGG:hsa05200]
[PUBMED:12244301]
[PUBMED:15156182]
[PUBMED:16899407]
[PUBMED:12621137]
[PUBMED:21193867]
[PUBMED:16001072]
[PUBMED:11707511]
[PUBMED:11253051]
[PUBMED:11071626]
[PUBMED:17251915]
[PUBMED:11736900]
[PUBMED:16557281]
[PUBMED:16699851]
[PUBMED:16189702]
[PUBMED:11902573]
[PUBMED:16555243]
[PUBMED:8069858]
[PUBMED:15310786]
[PUBMED:9834202]
[PUBMED:16700615]
[PUBMED:12545153]
[PUBMED:15656799]
[PUBMED:12154354]
[PUBMED:11895903]
[PUBMED:11527574]
[PUBMED:16326109]
[PUBMED:16339096]
[PUBMED:11160144]
[PUBMED:15724144]
[PUBMED:12951584]
[PUBMED:10647931]
[PUBMED:16881963]
[PUBMED:15557758]
[PUBMED:11477132]
[PUBMED:15721476]
[PUBMED:15625120]
[PUBMED:16236521]
[PUBMED:14967450]
[PUBMED:15942304]
[PUBMED:17287871]
[PUBMED:14634372]
[PUBMED:15573119]
[PUBMED:15009714]
[PUBMED:16112428]
[PUBMED:15611513]
[PUBMED:16001050]
[PUBMED:15349822]
[PUBMED:16551846]
[PUBMED:15978322]
[PUBMED:15774796]
[PUBMED:16352814]
[PUBMED:12951588]
[PUBMED:10944551]
[PUBMED:10740269]
[PUBMED:15639402]
[PUBMED:12407699]
[PUBMED:11130178]
[PUBMED:15109562]
[PUBMED:11170304]
[PUBMED:11276000]
[PUBMED:9643506]
[PUBMED:16248975]
[PUBMED:16242838]
[PUBMED:12946833]
[PUBMED:11559746]
[PUBMED:9196022]
[PUBMED:12079267]
[PUBMED:15468170]
[PUBMED:16064138]
[PUBMED:14580692]
[PUBMED:15082523]
[PUBMED:15551095]
[PUBMED:17062879]
[PUBMED:17211469]
[PUBMED:11720739]
[PUBMED:12588368]
[PUBMED:11057895]
[PUBMED:9422516]
[PUBMED:12894244]
[PUBMED:15479695]
[PUBMED:16189154]
[PUBMED:12878745]
[PUBMED:11900250]
[PUBMED:11103787]
[PUBMED:15122209]
[PUBMED:12711111]
[PUBMED:12243753]
[PUBMED:16306523]
[PUBMED:16702400]
[PUBMED:15270885]
[PUBMED:14685170]
[PUBMED:14586404]
[PUBMED:11078609]
[PUBMED:15284264]
[PUBMED:10505543]
[PUBMED:11223406]
[PUBMED:14982876]
[PUBMED:12648469]
[PUBMED:12867060]
[PUBMED:15711891]
[PUBMED:12094241]
[PUBMED:16642045]
[PUBMED:11463388]
[PUBMED:12762887]
[PUBMED:15746962]
[PUBMED:15823750]
[PUBMED:16750612]
[PUBMED:16484590]
[PUBMED:11459867]
[PUBMED:16146838]
[PUBMED:14556242]
[PUBMED:15947972]
[PUBMED:12563308]
[PUBMED:16946003]
[PUBMED:15948971]
[PUBMED:11407945]
[PUBMED:12737309]
[PUBMED:16095998]
[PUBMED:12351585]
[PUBMED:24508914]
[PUBMED:12084351]
[PUBMED:11807782]
[PUBMED:14695152]
[PUBMED:10453277]
[PUBMED:17554387]
[PUBMED:15841168]
[PUBMED:12616528]
[PUBMED:10403855]
[PUBMED:16054233]
[PUBMED:16474624]
[PUBMED:16822996]
[PUBMED:17028294]
[PUBMED:11224709]
[PUBMED:11750244]
[PUBMED:11905738]
[PUBMED:15719031]
[PUBMED:10843728]
[PUBMED:16110317]
[PUBMED:11721960]
[PUBMED:12741677]
[PUBMED:7585656]
[PUBMED:12801837]
[PUBMED:16551847]
[PUBMED:12459728]
[PUBMED:11431710]
[PUBMED:12468433]
[PUBMED:11165748]
[PUBMED:16042571]
[PUBMED:16508724]
[PUBMED:15000146]
[PUBMED:17149381]
[PUBMED:15948711]
[PUBMED:14747944]
[PUBMED:14737121]
[PUBMED:12379883]
[PUBMED:17158541]
[PUBMED:12850530]
[PUBMED:10835690]
[PUBMED:16870043]
Pertussis
[NCBI:218111]
[KEGG:hsa05133]
[PUBMED:20610650]
[PUBMED:12701623]
[PUBMED:15201703]
[PUBMED:18401006]
[PUBMED:20210554]
[PUBMED:16622221]
[PUBMED:17148436]
[PUBMED:21204863]
[PUBMED:20404851]
[PUBMED:10540218]
[PUBMED:16999837]
[PUBMED:16481212]
[PUBMED:16863919]
[PUBMED:16390441]
[PUBMED:21423776]
[PUBMED:17328678]
[PUBMED:12915094]
Prion diseases
[NCBI:101144]
[KEGG:hsa05020]
[PUBMED:15695097]
[PUBMED:18558863]
[PUBMED:11592845]
[PUBMED:15528202]
[PUBMED:17051207]
[PUBMED:18245809]
[PUBMED:14705136]
[PUBMED:10398674]
[PUBMED:15890824]
[PUBMED:14661267]
[PUBMED:15611724]
[PUBMED:15342004]
[PUBMED:18391177]
[PUBMED:17085779]
[PUBMED:12850426]
RAF-independent MAPK1/3 activation
[NCBI:1269503]
[REACTOME:R-HSA-112409]
[PUBMED:21135874]
[PUBMED:22569528]
[PUBMED:23954936]
Rheumatoid arthritis
[NCBI:200309]
[KEGG:hsa05323]
[PUBMED:9627005]
[PUBMED:17195034]
[PUBMED:15059264]
[PUBMED:17380158]
[PUBMED:20651747]
[PUBMED:19455385]
[PUBMED:20305562]
[PUBMED:20510236]
[PUBMED:19184540]
[PUBMED:20392226]
[PUBMED:17502360]
[PUBMED:16313349]
[PUBMED:16127012]
[PUBMED:15055519]
[PUBMED:20036936]
[PUBMED:11861618]
[PUBMED:19585227]
[PUBMED:20193003]
Salmonella infection
[NCBI:375172]
[KEGG:hsa05132]
[PUBMED:18407067]
[PUBMED:18411289]
[PUBMED:18778407]
[PUBMED:20123714]
[PUBMED:20158475]
[PUBMED:19779561]
[PUBMED:18026123]
[PUBMED:19930040]
[PUBMED:12675800]
[PUBMED:11755407]
[PUBMED:11489966]
[PUBMED:19775254]
[PUBMED:20943123]
[PUBMED:17690885]
[PUBMED:16938850]
[PUBMED:20526845]
[PUBMED:11567004]
[PUBMED:17074883]
[PUBMED:11825778]
[PUBMED:17071592]
[PUBMED:16800847]
[PUBMED:16611232]
[PUBMED:10499590]
Senescence-Associated Secretory Phenotype (SASP)
[NCBI:1270431]
[REACTOME:R-HSA-2559582]
[PUBMED:18411265]
[PUBMED:21979375]
[PUBMED:18267069]
[PUBMED:19597488]
[PUBMED:19218920]
[PUBMED:20818427]
[PUBMED:11114305]
[PUBMED:8617720]
[PUBMED:22178396]
[PUBMED:19805069]
[PUBMED:23770676]
[PUBMED:8384717]
[PUBMED:18555777]
[PUBMED:21686281]
[PUBMED:20351173]
[PUBMED:8688489]
[PUBMED:19053174]
[PUBMED:8234276]
[PUBMED:18555778]
Signal Transduction
[NCBI:1269379]
[REACTOME:R-HSA-162582]
[PUBMED:17604717]
[PUBMED:19648010]
[PUBMED:16260143]
[PUBMED:11742412]
[PUBMED:19536106]
[PUBMED:15863030]
[PUBMED:19379690]
[PUBMED:19458711]
[PUBMED:19935667]
[PUBMED:21252999]
[PUBMED:15520807]
[PUBMED:17496910]
[PUBMED:15450248]
[PUBMED:18043707]
[PUBMED:16939974]
[PUBMED:19762341]
[PUBMED:18483217]
[PUBMED:17084981]
[PUBMED:21781017]
[PUBMED:19619488]
Signaling by Interleukins
[NCBI:1269318]
[REACTOME:R-HSA-449147]
[PUBMED:19302047]
[PUBMED:12445398]
TNF signaling pathway
[NCBI:812256]
[KEGG:hsa04668]
[PUBMED:20489699]
[PUBMED:14532286]
[PUBMED:21232019]
[PUBMED:11897488]
[PUBMED:22296764]
[PUBMED:10581243]
[PUBMED:23085193]
[PUBMED:23531747]
Th17 cell differentiation
[NCBI:1469482]
[KEGG:hsa04659]
[PUBMED:23325835]
[PUBMED:23036716]
[PUBMED:20488727]
[PUBMED:21151104]
[PUBMED:21084214]
[PUBMED:20054607]
[PUBMED:22754770]
[PUBMED:22640807]
[PUBMED:19379825]
[PUBMED:22133865]
[PUBMED:22324470]
[PUBMED:17768419]
[PUBMED:18408735]
[PUBMED:21776333]
[PUBMED:26253381]
[PUBMED:16200068]
[PUBMED:18362914]
[PUBMED:24325586]
[PUBMED:19381306]
[PUBMED:18166487]
Toll-like receptor signaling pathway
[NCBI:83076]
[KEGG:hsa04620]
[PUBMED:16924467]
[PUBMED:17395581]
[PUBMED:17637696]
[PUBMED:12734364]
[PUBMED:17507094]
[PUBMED:14698224]
[PUBMED:11101877]
[PUBMED:16497588]
[PUBMED:14751764]
[PUBMED:17275323]
[PUBMED:17457343]
[PUBMED:16932750]
Transcriptional misregulation in cancer
[NCBI:523016]
[KEGG:hsa05202]
[PUBMED:17327229]
[PUBMED:20190806]
[PUBMED:20145147]
[PUBMED:11313274]
[PUBMED:11863357]
[PUBMED:19472090]
[PUBMED:18330902]
[PUBMED:19738075]
[PUBMED:15024077]
[PUBMED:12032780]
[PUBMED:14630078]
[PUBMED:21765642]
[PUBMED:19564705]
[PUBMED:17101797]
[PUBMED:15160934]
[PUBMED:15688424]
[PUBMED:15985538]
[PUBMED:12527902]
[PUBMED:12511414]
[PUBMED:11607818]
[PUBMED:17222504]
[PUBMED:15826838]
[PUBMED:21747944]
[PUBMED:19406209]
[PUBMED:10350329]
[PUBMED:21779514]
[PUBMED:18563191]
[PUBMED:16946003]
[PUBMED:17250957]
[PUBMED:12670461]
[PUBMED:12529654]
[PUBMED:18855877]
[PUBMED:17505060]
[PUBMED:20153925]
[PUBMED:20490326]
[PUBMED:12130514]
[PUBMED:18648544]
[PUBMED:19855079]
[PUBMED:10717473]
[PUBMED:20478527]
[PUBMED:11340171]
[PUBMED:16169901]
[PUBMED:14998494]
[PUBMED:19233641]
[PUBMED:19133982]
[PUBMED:12393465]
[PUBMED:19059936]
[PUBMED:18172298]
[PUBMED:10500199]
[PUBMED:19141473]
[PUBMED:10537274]
[PUBMED:15156184]
[PUBMED:14701735]
[PUBMED:19422821]
[PUBMED:21518926]
[PUBMED:18850010]
[PUBMED:19075677]
[PUBMED:18457914]
[PUBMED:12527906]
[PUBMED:15644444]
[PUBMED:10784387]
[PUBMED:17024155]
[PUBMED:19075268]
[PUBMED:15826834]
[PUBMED:21849159]
[PUBMED:21123453]
[PUBMED:20974671]
[PUBMED:20863376]
Tuberculosis
[NCBI:213780]
[KEGG:hsa05152]
[PUBMED:20199890]
[PUBMED:21274449]
[PUBMED:17359235]
[PUBMED:20415982]
[PUBMED:18541216]
[PUBMED:19369951]
[PUBMED:15083155]
[PUBMED:11378475]
[PUBMED:15228522]
[PUBMED:19634703]
[PUBMED:21274433]
[PUBMED:19563525]
[PUBMED:18407066]
[PUBMED:18288961]
[PUBMED:16200082]
[PUBMED:17785780]
[PUBMED:11932234]
Validated transcriptional targets of AP1 family members Fra1 and Fra2
[NCBI:169349]
[Pathway Interaction Database:fra_pathway]
[PUBMED:20386569]
[PUBMED:1827665]
[PUBMED:17510314]
[PUBMED:17001307]
[PUBMED:19419315]
[PUBMED:12121977]
[PUBMED:15790882]
[PUBMED:18435914]
[PUBMED:1406676]
[PUBMED:20543861]
[PUBMED:19687301]
[PUBMED:9651314]
[PUBMED:20392257]
[PUBMED:20472895]
[PUBMED:16554298]
[PUBMED:17496887]
[PUBMED:19995753]
[PUBMED:8058317]
[PUBMED:2497053]
[PUBMED:8798756]
[PUBMED:17347653]
[PUBMED:18331200]
[PUBMED:19966854]
[PUBMED:17882273]
[PUBMED:9858556]
[PUBMED:3130660]
[PUBMED:19289495]
[PUBMED:11756554]
[PUBMED:1945831]
[PUBMED:15688012]
[PUBMED:8441422]
[PUBMED:17371847]
[PUBMED:10421804]
[PUBMED:2110368]
[PUBMED:18548006]
[PUBMED:20353950]
[PUBMED:15229648]
[PUBMED:11425864]
[PUBMED:15601844]
[PUBMED:10918580]
[PUBMED:9858557]
[PUBMED:19716794]
[PUBMED:9819396]
[PUBMED:17052890]
[PUBMED:20398633]
[PUBMED:20371606]
[PUBMED:10359014]
[PUBMED:15143165]
[PUBMED:15618352]
[PUBMED:9160889]
[PUBMED:12052899]
[PUBMED:9409785]
[PUBMED:15291758]
[PUBMED:1923525]
[PUBMED:7759510]
[PUBMED:15608675]
[PUBMED:14519134]
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amb2 Integrin signaling
[NCBI:137945]
[Pathway Interaction Database:amb2_neutrophils_pathway]
[PUBMED:15004192]
[PUBMED:16260637]
[PUBMED:8874219]
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[PUBMED:16403785]