full name
growth factor receptor bound protein 10

synonyms
Grb-10, GRB-IR, IRBP, MEG1, RSS, GRB10, ENSG00000106070

HGNC
HGNC:4564

Entrez Gene
Gene:2887

ENSEMBL
ENSG00000106070

location
chr: 7
start: 50657760
stop: 50861159
strand: -

transcripts
ENST00000335866.3
ENST00000357271.5
ENST00000398812.2
ENST00000398810.2

pathways
Axon guidance [NCBI:83065] [KEGG:hsa04360] [NCBI:1270303] [REACTOME:R-HSA-422475] [PUBMED:14682358] [PUBMED:15084255] [PUBMED:11687826] [PUBMED:15818466] [PUBMED:15363605] [PUBMED:12471249] [PUBMED:15630019] [PUBMED:11891122] [PUBMED:15960985] [PUBMED:12677003]
Developmental Biology [NCBI:1270302] [REACTOME:R-HSA-1266738]
IGF1 pathway [NCBI:137992] [Pathway Interaction Database:igf1_pathway] [PUBMED:15003536] [PUBMED:10576742] [PUBMED:8621590] [PUBMED:9346240] [PUBMED:16932738] [PUBMED:8662827] [PUBMED:15976035] [PUBMED:11572799] [PUBMED:14550766] [PUBMED:15070696] [PUBMED:9346905] [PUBMED:10490655] [PUBMED:1378290] [PUBMED:9480911] [PUBMED:9442079] [PUBMED:7534289] [PUBMED:8265614] [PUBMED:9748296] [PUBMED:11884618] [PUBMED:12538620] [PUBMED:8798417] [PUBMED:8764099] [PUBMED:8505282] [PUBMED:7540132] [PUBMED:12048182] [PUBMED:15611085] [PUBMED:14604996] [PUBMED:7642582] [PUBMED:11836447] [PUBMED:8776723] [PUBMED:7513703] [PUBMED:9506989]
IRS activation [NCBI:1269430] [REACTOME:R-HSA-74713]
Insulin Pathway [NCBI:138026] [Pathway Interaction Database:insulin_pathway] [PUBMED:8491186] [PUBMED:9111325] [PUBMED:7629070] [PUBMED:10499514] [PUBMED:11121405] [PUBMED:10660596] [PUBMED:8196603] [PUBMED:11096081] [PUBMED:8524328] [PUBMED:9891043] [PUBMED:12242347] [PUBMED:2123524] [PUBMED:9369444] [PUBMED:1375946] [PUBMED:9348199] [PUBMED:8826975] [PUBMED:8316835] [PUBMED:8999839] [PUBMED:8449939] [PUBMED:10807907] [PUBMED:1599438] [PUBMED:8265614] [PUBMED:11171109] [PUBMED:11821390] [PUBMED:12687004] [PUBMED:7806540] [PUBMED:11154281] [PUBMED:8244979] [PUBMED:8798417] [PUBMED:1381348] [PUBMED:7581368] [PUBMED:15787604] [PUBMED:8385105] [PUBMED:11551902] [PUBMED:8114695] [PUBMED:11997497] [PUBMED:11001060] [PUBMED:11309621] [PUBMED:9109420] [PUBMED:8383963] [PUBMED:12147684] [PUBMED:8144662] [PUBMED:12036959] [PUBMED:14734537] [PUBMED:7983051] [PUBMED:9083103] [PUBMED:15210700] [PUBMED:9065430] [PUBMED:11297536] [PUBMED:10544179] [PUBMED:1321126] [PUBMED:11502760] [PUBMED:8978681] [PUBMED:8999972] [PUBMED:14690593] [PUBMED:11832334] [PUBMED:9447983] [PUBMED:15192089] [PUBMED:8524413] [PUBMED:7685165] [PUBMED:10329736] [PUBMED:11287630] [PUBMED:15486046] [PUBMED:10330191] [PUBMED:8626723]
Insulin receptor signalling cascade [NCBI:1269429] [REACTOME:R-HSA-74751] [PUBMED:9677303] [PUBMED:11282018]
PDGFR-beta signaling pathway [NCBI:138071] [Pathway Interaction Database:pdgfrbpathway] [PUBMED:7545675] [PUBMED:16769879] [PUBMED:12652307] [PUBMED:10463951] [PUBMED:9742401] [PUBMED:8086421] [PUBMED:10391677] [PUBMED:7739538] [PUBMED:9989826] [PUBMED:10734138] [PUBMED:15753096] [PUBMED:7692233] [PUBMED:11489946] [PUBMED:10837138] [PUBMED:10229199] [PUBMED:10821867] [PUBMED:11709084] [PUBMED:11389443] [PUBMED:12958184] [PUBMED:10734113] [PUBMED:15161943] [PUBMED:12149261] [PUBMED:16456542] [PUBMED:16224065] [PUBMED:8619809] [PUBMED:15494217] [PUBMED:1849073] [PUBMED:11085978] [PUBMED:2544881] [PUBMED:7622571] [PUBMED:10779329] [PUBMED:15944146] [PUBMED:11027258] [PUBMED:1708307] [PUBMED:8940081] [PUBMED:11854295] [PUBMED:8195171] [PUBMED:12424235] [PUBMED:7935392] [PUBMED:14966296] [PUBMED:16537894]
RET signaling [NCBI:1427866] [REACTOME:R-HSA-8853659] [PUBMED:15013219] [PUBMED:17036197]
Signal Transduction [NCBI:1269379] [REACTOME:R-HSA-162582] [PUBMED:17604717] [PUBMED:19648010] [PUBMED:16260143] [PUBMED:11742412] [PUBMED:19536106] [PUBMED:15863030] [PUBMED:19379690] [PUBMED:19458711] [PUBMED:19935667] [PUBMED:21252999] [PUBMED:15520807] [PUBMED:17496910] [PUBMED:15450248] [PUBMED:18043707] [PUBMED:16939974] [PUBMED:19762341] [PUBMED:18483217] [PUBMED:17084981] [PUBMED:21781017] [PUBMED:19619488]
Signal attenuation [NCBI:1269441] [REACTOME:R-HSA-74749]
Signaling by Insulin receptor [NCBI:1269428] [REACTOME:R-HSA-74752] [PUBMED:8276779]
Signaling by SCF-KIT [NCBI:1269487] [REACTOME:R-HSA-1433557] [PUBMED:17350321] [PUBMED:16483568] [PUBMED:7688988] [PUBMED:19540337] [PUBMED:16475976] [PUBMED:15526160]
Signaling events mediated by Stem cell factor receptor (c-Kit) [NCBI:138068] [Pathway Interaction Database:kitpathway] [PUBMED:12909618] [PUBMED:10364466] [PUBMED:10673502] [PUBMED:15315962] [PUBMED:12192036] [PUBMED:12444928] [PUBMED:15504549] [PUBMED:8950973] [PUBMED:11071635] [PUBMED:12149208] [PUBMED:11369651] [PUBMED:9038210] [PUBMED:10679268] [PUBMED:15465815] [PUBMED:10523831] [PUBMED:8611693] [PUBMED:15676208] [PUBMED:11805142] [PUBMED:10637471] [PUBMED:9872323] [PUBMED:11809791] [PUBMED:11520784] [PUBMED:12691919] [PUBMED:10397721] [PUBMED:15611091] [PUBMED:12356726] [PUBMED:9528781] [PUBMED:1381360] [PUBMED:9651683] [PUBMED:10849422] [PUBMED:9355737]
Signaling events mediated by VEGFR1 and VEGFR2 [NCBI:137940] [Pathway Interaction Database:vegfr1_2_pathway] [PUBMED:9398617] [PUBMED:9405464] [PUBMED:11494124] [PUBMED:12963813] [PUBMED:11756651] [PUBMED:10744763] [PUBMED:15060076] [PUBMED:9600074] [PUBMED:10376603] [PUBMED:11425855] [PUBMED:16337972] [PUBMED:12154000] [PUBMED:11978735] [PUBMED:10692392] [PUBMED:16763158] [PUBMED:10361126] [PUBMED:10748121] [PUBMED:12598525] [PUBMED:15026417] [PUBMED:11948691] [PUBMED:16966330] [PUBMED:16835467] [PUBMED:10409677] [PUBMED:10908731] [PUBMED:8903320] [PUBMED:15962004] [PUBMED:16633338] [PUBMED:11387210] [PUBMED:16839566] [PUBMED:11312102] [PUBMED:10207622] [PUBMED:16787925] [PUBMED:12171920] [PUBMED:12509223] [PUBMED:16760434] [PUBMED:14724572] [PUBMED:11704645] [PUBMED:12821150] [PUBMED:12881528] [PUBMED:9790910] [PUBMED:10376602] [PUBMED:15247219] [PUBMED:11333271] [PUBMED:12214271] [PUBMED:9804796] [PUBMED:11986311] [PUBMED:9182576] [PUBMED:15217908] [PUBMED:10749680] [PUBMED:16763549]
Signaling events regulated by Ret tyrosine kinase [NCBI:137915] [Pathway Interaction Database:ret_pathway] [PUBMED:11002419] [PUBMED:17050626] [PUBMED:11360177] [PUBMED:7478523] [PUBMED:12176011] [PUBMED:12771945] [PUBMED:14607833] [PUBMED:7665556] [PUBMED:8631863] [PUBMED:11470823] [PUBMED:15966897] [PUBMED:12087092] [PUBMED:16820412] [PUBMED:15657578] [PUBMED:10208419] [PUBMED:9182757] [PUBMED:8662982] [PUBMED:9047383] [PUBMED:12063395] [PUBMED:15569713] [PUBMED:15286081] [PUBMED:10448070] [PUBMED:16227613] [PUBMED:11390647] [PUBMED:15351743] [PUBMED:8674117] [PUBMED:11313948] [PUBMED:2181380] [PUBMED:9047384] [PUBMED:8570170] [PUBMED:11886862] [PUBMED:9632781] [PUBMED:16153436] [PUBMED:11000521]
mTOR signaling pathway [NCBI:83059] [KEGG:hsa04150] [NCBI:138001] [Pathway Interaction Database:mtor_4pathway] [PUBMED:17277771] [PUBMED:15341740] [PUBMED:12172553] [PUBMED:15718470] [PUBMED:14651849] [PUBMED:15268862] [PUBMED:15306821] [PUBMED:26046644] [PUBMED:12869586] [PUBMED:24556838] [PUBMED:17928295] [PUBMED:9427642] [PUBMED:18046414] [PUBMED:12912918] [PUBMED:16286006] [PUBMED:26658722] [PUBMED:24842496] [PUBMED:23465396] [PUBMED:17709744] [PUBMED:17599906] [PUBMED:16919458] [PUBMED:10364159] [PUBMED:15342917] [PUBMED:11500364] [PUBMED:19812304] [PUBMED:12482958] [PUBMED:11729323] [PUBMED:16962653] [PUBMED:18952604] [PUBMED:9465032] [PUBMED:1496022] [PUBMED:10567431] [PUBMED:19114562] [PUBMED:17510057] [PUBMED:18604198] [PUBMED:15545625] [PUBMED:11914378] [PUBMED:17461779] [PUBMED:9445476] [PUBMED:18497260] [PUBMED:12604610] [PUBMED:15071500] [PUBMED:18925875] [PUBMED:12906785] [PUBMED:11287630] [PUBMED:15004009] [PUBMED:16756488] [PUBMED:17043309] [PUBMED:18198340] [PUBMED:12820960] [PUBMED:12747827] [PUBMED:17053147] [PUBMED:15851026] [PUBMED:15467718] [PUBMED:18762023] [PUBMED:25242279] [PUBMED:24698685] [PUBMED:11175345] [PUBMED:27304501] [PUBMED:18411301] [PUBMED:11500365] [PUBMED:17693255] [PUBMED:23694989] [PUBMED:12231510] [PUBMED:19446321] [PUBMED:11418588] [PUBMED:19258318] [PUBMED:18439900] [PUBMED:19225151] [PUBMED:26185979] [PUBMED:10357815] [PUBMED:26269525] [PUBMED:23421405] [PUBMED:9271440] [PUBMED:16915281] [PUBMED:17141160] [PUBMED:15249583] [PUBMED:12912989] [PUBMED:27027448] [PUBMED:18423201] [PUBMED:19211835] [PUBMED:9204908] [PUBMED:26700098] [PUBMED:18566587] [PUBMED:17386266]