full name
glucuronidase beta

synonyms
BG, MPS7, GUSB, ENSG00000169919

HGNC
HGNC:4696

Entrez Gene
Gene:2990

ENSEMBL
ENSG00000169919

location
chr: 7
start: 65425671
stop: 65447301
strand: -

OMIM
OMIM:611499: GUSB (Autosomal recessive inheritance)
OMIM:253220: Mucopolysaccharidosis VII

transcripts
NM_000181.3

pathways
Chondroitin sulfate degradation [NCBI:413376] [KEGG:hsa_M00077]
Dermatan sulfate degradation [NCBI:413375] [KEGG:hsa_M00076]
Drug metabolism - other enzymes [NCBI:83033] [KEGG:hsa00983] [PUBMED:15514566] [PUBMED:15173095] [PUBMED:15788214] [PUBMED:11379777] [PUBMED:10976516] [PUBMED:11489791] [PUBMED:16048561] [PUBMED:16880012]
Glucuronate pathway (uronate pathway) [NCBI:997799] [KEGG:hsa_M00014]
Glycosaminoglycan degradation [NCBI:82981] [KEGG:hsa00531] [PUBMED:27570] [PUBMED:3161730]
Glycosaminoglycan metabolism [NCBI:1269972] [REACTOME:R-HSA-1630316] [PUBMED:18201392] [PUBMED:20301236] [PUBMED:820626]
HS-GAG degradation [NCBI:1269983] [REACTOME:R-HSA-2024096] [PUBMED:15647514]
Heparan sulfate degradation [NCBI:413377] [KEGG:hsa_M00078]
Heparan sulfate/heparin (HS-GAG) metabolism [NCBI:1269980] [REACTOME:R-HSA-1638091] [PUBMED:11102866] [PUBMED:19111581] [PUBMED:10716625] [PUBMED:9251237]
Hyaluronan metabolism [NCBI:1269973] [REACTOME:R-HSA-2142845] [PUBMED:15229478] [PUBMED:10930435] [PUBMED:19442142]
Hyaluronan uptake and degradation [NCBI:1269975] [REACTOME:R-HSA-2160916] [PUBMED:9839614] [PUBMED:22216413] [PUBMED:14514708]
Immune System [NCBI:1269170] [REACTOME:R-HSA-168256]
Innate Immune System [NCBI:1269203] [REACTOME:R-HSA-168249]
Lysosome [NCBI:99052] [KEGG:hsa04142] [PUBMED:2943218] [PUBMED:12628346] [PUBMED:1883197] [PUBMED:18635948] [PUBMED:15987739]
Metabolic pathways [NCBI:132956] [KEGG:hsa01100]
Metabolism [NCBI:1269956] [REACTOME:R-HSA-1430728]
Metabolism of carbohydrates [NCBI:1269957] [REACTOME:R-HSA-71387]
Neutrophil degranulation [NCBI:1457780] [REACTOME:R-HSA-6798695] [PUBMED:20338884] [PUBMED:1378856] [PUBMED:17627888] [PUBMED:23650620] [PUBMED:8692836]
Pentose and glucuronate interconversions [NCBI:82929] [KEGG:hsa00040] [PUBMED:10913097] [PUBMED:15697206] [PUBMED:15901685] [PUBMED:11741871] [PUBMED:10572115]
Porphyrin and chlorophyll metabolism [NCBI:83021] [KEGG:hsa00860] [PUBMED:12195810] [PUBMED:11283349] [PUBMED:10217486] [PUBMED:11007789] [PUBMED:10518530] [PUBMED:12055304] [PUBMED:12196148] [PUBMED:17506685] [PUBMED:16245042] [PUBMED:23922391] [PUBMED:23042036] [PUBMED:9461500]