full name
cytochrome p450 oxidoreductase

synonyms
CPR, CYPOR, P450R, POR, ENSG00000127948

HGNC
HGNC:9208

Entrez Gene
Gene:5447

ENSEMBL
ENSG00000127948
ENSG00000262569

location
chr: 7
start: 75544420
stop: 75616173
strand: +

OMIM
OMIM:124015: POR (Autosomal recessive inheritance)
OMIM:201750: Antley-Bixler syndrome with genital anomalies and disordered steroidogenesis
OMIM:613571: Disordered steroidogenesis due to cytochrome P450 oxidoreductase

transcripts
NM_000941.2

pathways
Biological oxidations [NCBI:1270189] [REACTOME:R-HSA-211859]
Cytochrome P450 - arranged by substrate type [NCBI:1270191] [REACTOME:R-HSA-211897] [PUBMED:16584116] [PUBMED:15102545] [PUBMED:12369887]
Metabolism [NCBI:1269956] [REACTOME:R-HSA-1430728]
Phase 1 - Functionalization of compounds [NCBI:1270190] [REACTOME:R-HSA-211945] [PUBMED:12369887] [PUBMED:17125408] [PUBMED:16584116]
bile acid biosynthesis, neutral pathway [NCBI:545316] [BIOCYC:HUMAN_PWY-6061] [PUBMED:18538142] [PUBMED:17346171] [PUBMED:15769750] [PUBMED:11146090] [PUBMED:12543708] [PUBMED:9390170] [PUBMED:3746130] [PUBMED:11673457] [PUBMED:18815433] [PUBMED:6736016] [PUBMED:3459552] [PUBMED:9307041] [PUBMED:11969205] [PUBMED:9538213] [PUBMED:9215542] [PUBMED:624713] [PUBMED:2848026]
melatonin degradation I [NCBI:545356] [BIOCYC:HUMAN_PWY-6398] [PUBMED:18344019] [PUBMED:18717775] [PUBMED:12899443] [PUBMED:17198536] [PUBMED:16219483] [PUBMED:9181522] [PUBMED:15981996] [PUBMED:12662344] [PUBMED:11485009] [PUBMED:18155917] [PUBMED:15616152] [PUBMED:16793870]
superpathway of melatonin degradation [NCBI:545359] [BIOCYC:HUMAN_PWY-6402]
superpathway of tryptophan utilization [NCBI:835392] [BIOCYC:HUMAN_PWY66-401]
vitamin D3 biosynthesis [NCBI:545291] [BIOCYC:HUMAN_PWY-6076] [PUBMED:17196157] [PUBMED:15951480] [PUBMED:15585789] [PUBMED:18089691] [PUBMED:15465040] [PUBMED:12520537] [PUBMED:11172626] [PUBMED:15544953] [PUBMED:16563471] [PUBMED:17023693] [PUBMED:2719932] [PUBMED:194588] [PUBMED:12670492] [PUBMED:17646648]