full name
protein tyrosine phosphatase, non-receptor type 12

synonyms
PTP-PEST, PTPG1, PTPN12, ENSG00000127947

HGNC
HGNC:9645

Entrez Gene
Gene:5782

ENSEMBL
ENSG00000127947

location
chr: 7
start: 77166773
stop: 77269388
strand: +

OMIM
OMIM:600079: PTPN12
OMIM:114500: Colon cancer, somatic

transcripts
NM_002835.3
NM_001131008.1
NM_001131009.1

pathways
Downregulation of ERBB2 signaling [NCBI:1457793] [REACTOME:R-HSA-8863795] [PUBMED:19933325] [PUBMED:21376233] [PUBMED:17210635] [PUBMED:12239347] [PUBMED:25081058]
EGFR downregulation [NCBI:1269385] [REACTOME:R-HSA-182971] [PUBMED:11283727] [PUBMED:15021893] [PUBMED:14641021]
SHC1 events in ERBB2 signaling [NCBI:1269490] [REACTOME:R-HSA-1250196]
Signal Transduction [NCBI:1269379] [REACTOME:R-HSA-162582] [PUBMED:17604717] [PUBMED:19648010] [PUBMED:16260143] [PUBMED:11742412] [PUBMED:19536106] [PUBMED:15863030] [PUBMED:19379690] [PUBMED:19458711] [PUBMED:19935667] [PUBMED:21252999] [PUBMED:15520807] [PUBMED:17496910] [PUBMED:15450248] [PUBMED:18043707] [PUBMED:16939974] [PUBMED:19762341] [PUBMED:18483217] [PUBMED:17084981] [PUBMED:21781017] [PUBMED:19619488]
Signaling by EGFR [NCBI:1269380] [REACTOME:R-HSA-177929] [PUBMED:10459005] [PUBMED:10404636] [PUBMED:12297041] [PUBMED:15142631]
Signaling by ERBB2 [NCBI:1269489] [REACTOME:R-HSA-1227986]
Signaling by PDGF [NCBI:1269478] [REACTOME:R-HSA-186797] [PUBMED:15207811] [PUBMED:10508235] [PUBMED:9739761]