full name
ATP binding cassette subfamily B member 4

synonyms
ABC21, GBD1, ICP3, MDR2, MDR2%2F3, MDR3, PFIC-3, PGY3, ABCB4, ENSG00000005471

HGNC
HGNC:45

Entrez Gene
Gene:5244

ENSEMBL
ENSG00000005471

location
chr: 7
start: 87031361
stop: 87105019
strand: -

OMIM
OMIM:171060: ABCB4 (Autosomal dominant inheritance,Autosomal recessive inheritance)
OMIM:614972: Cholestasis, intrahepatic, of pregnancy, 3
OMIM:602347: Cholestasis, progressive familial intrahepatic 3
OMIM:600803: Gallbladder disease 1

transcripts
NM_018850.2
NM_000443.3
NM_018849.2

pathways
ABC transporters [NCBI:83035] [KEGG:hsa02010] [PUBMED:10557362] [PUBMED:18424520] [PUBMED:9799792] [PUBMED:18375759] [PUBMED:16135226] [PUBMED:18326572] [PUBMED:18805970] [PUBMED:17214741] [PUBMED:11929526] [PUBMED:11731493] [PUBMED:16109926] [PUBMED:17873039]
ABC-family proteins mediated transport [NCBI:1269904] [REACTOME:R-HSA-382556] [PUBMED:11435397] [PUBMED:12045106] [PUBMED:19234479]
Bile secretion [NCBI:193146] [KEGG:hsa04976] [PUBMED:11826283] [PUBMED:19273385] [PUBMED:12663868] [PUBMED:15758646] [PUBMED:18837079] [PUBMED:15975683] [PUBMED:17404808] [PUBMED:18377365] [PUBMED:16706681] [PUBMED:10728790] [PUBMED:14659471] [PUBMED:18670431] [PUBMED:12483266] [PUBMED:19273238] [PUBMED:18668439] [PUBMED:18371245] [PUBMED:14999673] [PUBMED:11316487] [PUBMED:18081658] [PUBMED:19482594] [PUBMED:20103563]
Fatty acid, triacylglycerol, and ketone body metabolism [NCBI:1270010] [REACTOME:R-HSA-535734]
Metabolism [NCBI:1269956] [REACTOME:R-HSA-1430728]
Metabolism of lipids and lipoproteins [NCBI:1270001] [REACTOME:R-HSA-556833]
PPARA activates gene expression [NCBI:1270030] [REACTOME:R-HSA-1989781] [PUBMED:10529898] [PUBMED:18288277] [PUBMED:11330046] [PUBMED:20936127] [PUBMED:14999402]
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) [NCBI:1270029] [REACTOME:R-HSA-400206] [PUBMED:18288277] [PUBMED:10529898] [PUBMED:16476485] [PUBMED:16503871]
Transmembrane transport of small molecules [NCBI:1269903] [REACTOME:R-HSA-382551]