full name
asparagine synthetase (glutamine-hydrolyzing)

synonyms
TS11, ASNS, ENSG00000070669

HGNC
HGNC:753

Entrez Gene
Gene:440

ENSEMBL
ENSG00000070669

location
chr: 7
start: 97481429
stop: 97501854
strand: -

OMIM
OMIM:108370: ASNS (Autosomal dominant inheritance,Autosomal recessive inheritance)
OMIM:615574: Asparagine synthetase deficiency

transcripts
NM_001178076.1
NM_001178075.1
NM_001673.4
NM_183356.3
NM_001178077.1
NM_133436.3

pathways
ATF4 activates genes [NCBI:1268762] [REACTOME:R-HSA-380994] [PUBMED:18840095] [PUBMED:16931790] [PUBMED:14742429] [PUBMED:16687408] [PUBMED:20022965] [PUBMED:18426796] [PUBMED:14630918] [PUBMED:16912112]
Alanine, aspartate and glutamate metabolism [NCBI:101142] [KEGG:hsa00250] [PUBMED:9687539]
Amino acid synthesis and interconversion (transamination) [NCBI:1270159] [REACTOME:R-HSA-70614]
Metabolic pathways [NCBI:132956] [KEGG:hsa01100]
Metabolism [NCBI:1269956] [REACTOME:R-HSA-1430728]
Metabolism of amino acids and derivatives [NCBI:1270158] [REACTOME:R-HSA-71291]
Metabolism of proteins [NCBI:1268677] [REACTOME:R-HSA-392499]
PERK regulates gene expression [NCBI:1268761] [REACTOME:R-HSA-381042] [PUBMED:18048764] [PUBMED:17956313] [PUBMED:18038217] [PUBMED:18436705]
Unfolded Protein Response (UPR) [NCBI:1268756] [REACTOME:R-HSA-381119] [PUBMED:18436705] [PUBMED:18038217] [PUBMED:27067637] [PUBMED:16365312] [PUBMED:18048764] [PUBMED:15952902]
asparagine biosynthesis [NCBI:142134] [BIOCYC:HUMAN_ASPARAGINE-BIOSYNTHESIS] [PUBMED:16039064] [PUBMED:23403946] [PUBMED:2564390]