full name
protein kinase cAMP-dependent type II regulatory subunit beta

synonyms
PRKAR2, RII-BETA, PRKAR2B, ENSG00000005249

HGNC
HGNC:9392

Entrez Gene
Gene:5577

ENSEMBL
ENSG00000005249

location
chr: 7
start: 106685178
stop: 106802256
strand: +

transcripts
NM_002736.2

pathways
AURKA Activation by TPX2 [NCBI:1383018] [REACTOME:R-HSA-8854518] [PUBMED:14580337] [PUBMED:21147853] [PUBMED:22094468] [PUBMED:21347367]
Anchoring of the basal body to the plasma membrane [NCBI:1268847] [REACTOME:R-HSA-5620912] [PUBMED:21816947] [PUBMED:23747070] [PUBMED:19575670] [PUBMED:13978319] [PUBMED:23348840] [PUBMED:25047614] [PUBMED:20819941] [PUBMED:5661997] [PUBMED:21422230] [PUBMED:24469809] [PUBMED:23530209] [PUBMED:21725307] [PUBMED:21680046] [PUBMED:23351793] [PUBMED:21427764] [PUBMED:11676918] [PUBMED:22653444]
Aquaporin-mediated transport [NCBI:1269944] [REACTOME:R-HSA-445717] [PUBMED:11773613] [PUBMED:15901243] [PUBMED:20224213] [PUBMED:15340377] [PUBMED:16650285] [PUBMED:19448080] [PUBMED:17222168] [PUBMED:16107722] [PUBMED:15809071] [PUBMED:19096770] [PUBMED:15924268] [PUBMED:17961083]
Ca-dependent events [NCBI:1269588] [REACTOME:R-HSA-111996] [PUBMED:18083096] [PUBMED:11162741] [PUBMED:17697045] [PUBMED:16076488]
CaM pathway [NCBI:1269292] [REACTOME:R-HSA-111997] [PUBMED:10884684]
Calmodulin induced events [NCBI:1269293] [REACTOME:R-HSA-111933] [PUBMED:15381755]
Cell Cycle [NCBI:1269741] [REACTOME:R-HSA-1640170]
Cell Cycle, Mitotic [NCBI:1269763] [REACTOME:R-HSA-69278]
Centrosome maturation [NCBI:1269805] [REACTOME:R-HSA-380287] [PUBMED:17178454] [PUBMED:18437411]
Cilium Assembly [NCBI:1268846] [REACTOME:R-HSA-5617833] [PUBMED:21427764] [PUBMED:23351793] [PUBMED:25040720] [PUBMED:17955020] [PUBMED:22118932] [PUBMED:22653444] [PUBMED:22389062] [PUBMED:20399632] [PUBMED:25047619] [PUBMED:20395968] [PUBMED:23945166] [PUBMED:19575670] [PUBMED:24296415] [PUBMED:20145001] [PUBMED:19602418]
DAG and IP3 signaling [NCBI:1269291] [REACTOME:R-HSA-1489509] [PUBMED:16260143]
DAP12 interactions [NCBI:1269283] [REACTOME:R-HSA-2172127] [PUBMED:19120482] [PUBMED:17220916] [PUBMED:9490415] [PUBMED:18192027] [PUBMED:15884055]
DAP12 signaling [NCBI:1269284] [REACTOME:R-HSA-2424491] [PUBMED:15884055] [PUBMED:17110943] [PUBMED:17220916]
DARPP-32 events [NCBI:1269591] [REACTOME:R-HSA-180024] [PUBMED:14744247] [PUBMED:2908293]
Downstream signal transduction [NCBI:1269479] [REACTOME:R-HSA-186763] [PUBMED:10508235] [PUBMED:9739761]
EGFR interacts with phospholipase C-gamma [NCBI:1269381] [REACTOME:R-HSA-212718] [PUBMED:1501243]
Factors involved in megakaryocyte development and platelet production [NCBI:1269377] [REACTOME:R-HSA-983231] [PUBMED:16856888] [PUBMED:17635743] [PUBMED:17934486]
G-protein mediated events [NCBI:1269586] [REACTOME:R-HSA-112040] [PUBMED:9422713] [PUBMED:9218123]
G2/M Transition [NCBI:1269799] [REACTOME:R-HSA-69275]
Glucagon signaling in metabolic regulation [NCBI:1270108] [REACTOME:R-HSA-163359] [PUBMED:12626323]
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion [NCBI:1270107] [REACTOME:R-HSA-381676] [PUBMED:8830891] [PUBMED:15569269] [PUBMED:17306374] [PUBMED:9914469] [PUBMED:17900700] [PUBMED:11078440] [PUBMED:12475787] [PUBMED:11815463]
Hedgehog 'off' state [NCBI:1269636] [REACTOME:R-HSA-5610787] [PUBMED:21801010] [PUBMED:20395968] [PUBMED:23719536] [PUBMED:21502959]
Hemostasis [NCBI:1269340] [REACTOME:R-HSA-109582]
Immune System [NCBI:1269170] [REACTOME:R-HSA-168256]
Innate Immune System [NCBI:1269203] [REACTOME:R-HSA-168249]
Insulin signaling pathway [NCBI:83090] [KEGG:hsa04910] [PUBMED:11742412] [PUBMED:11343120] [PUBMED:15733744] [PUBMED:11282018] [PUBMED:10196204] [PUBMED:18291668] [PUBMED:9609110] [PUBMED:10567225] [PUBMED:12791379] [PUBMED:9748166] [PUBMED:15624019] [PUBMED:9445476] [PUBMED:9346240] [PUBMED:14635525] [PUBMED:16288289] [PUBMED:12867054] [PUBMED:15229476] [PUBMED:17344645] [PUBMED:9609111]
Integration of energy metabolism [NCBI:1270101] [REACTOME:R-HSA-163685] [PUBMED:15509864] [PUBMED:12721358] [PUBMED:12626323]
Loss of Nlp from mitotic centrosomes [NCBI:1269809] [REACTOME:R-HSA-380259] [PUBMED:12852856]
Loss of proteins required for interphase microtubule organization from the centrosome [NCBI:1269808] [REACTOME:R-HSA-380284] [PUBMED:12140259] [PUBMED:12852856]
Metabolism [NCBI:1269956] [REACTOME:R-HSA-1430728]
Mitotic G2-G2/M phases [NCBI:1269797] [REACTOME:R-HSA-453274]
NGF signalling via TRKA from the plasma membrane [NCBI:1269460] [REACTOME:R-HSA-187037] [PUBMED:11520933] [PUBMED:12676795] [PUBMED:10851172] [PUBMED:10579918]
Opioid Signalling [NCBI:1269584] [REACTOME:R-HSA-111885] [PUBMED:9422713] [PUBMED:9218123] [PUBMED:16612131]
Organelle biogenesis and maintenance [NCBI:1268838] [REACTOME:R-HSA-1852241] [PUBMED:8608592] [PUBMED:16103713]
PKA activation [NCBI:1269295] [REACTOME:R-HSA-163615] [PUBMED:2165385]
PKA activation in glucagon signalling [NCBI:1270109] [REACTOME:R-HSA-164378]
PKA-mediated phosphorylation of CREB [NCBI:1269294] [REACTOME:R-HSA-111931] [PUBMED:15337521] [PUBMED:16125054]
PLC beta mediated events [NCBI:1269587] [REACTOME:R-HSA-112043] [PUBMED:9218123] [PUBMED:16183910] [PUBMED:1335363]
PLC-gamma1 signalling [NCBI:1269472] [REACTOME:R-HSA-167021] [PUBMED:12676795] [PUBMED:10579907]
Recruitment of mitotic centrosome proteins and complexes [NCBI:1269806] [REACTOME:R-HSA-380270] [PUBMED:18437411] [PUBMED:17178454]
Regulation of PLK1 Activity at G2/M Transition [NCBI:1269803] [REACTOME:R-HSA-2565942] [PUBMED:12207013] [PUBMED:18615013] [PUBMED:13678582] [PUBMED:18378770] [PUBMED:18566290] [PUBMED:18477460] [PUBMED:22365832]
Regulation of insulin secretion [NCBI:1270102] [REACTOME:R-HSA-422356] [PUBMED:18200017] [PUBMED:11078440] [PUBMED:16321791] [PUBMED:11815463] [PUBMED:16556766]
Signal Transduction [NCBI:1269379] [REACTOME:R-HSA-162582] [PUBMED:17604717] [PUBMED:19648010] [PUBMED:16260143] [PUBMED:11742412] [PUBMED:19536106] [PUBMED:15863030] [PUBMED:19379690] [PUBMED:19458711] [PUBMED:19935667] [PUBMED:21252999] [PUBMED:15520807] [PUBMED:17496910] [PUBMED:15450248] [PUBMED:18043707] [PUBMED:16939974] [PUBMED:19762341] [PUBMED:18483217] [PUBMED:17084981] [PUBMED:21781017] [PUBMED:19619488]
Signaling by EGFR [NCBI:1269380] [REACTOME:R-HSA-177929] [PUBMED:10459005] [PUBMED:10404636] [PUBMED:12297041] [PUBMED:15142631]
Signaling by GPCR [NCBI:1269543] [REACTOME:R-HSA-372790] [PUBMED:16902930] [PUBMED:10202136] [PUBMED:18043707]
Signaling by Hedgehog [NCBI:1269633] [REACTOME:R-HSA-5358351] [PUBMED:19081070] [PUBMED:21801010] [PUBMED:15549094] [PUBMED:23719536]
Signaling by PDGF [NCBI:1269478] [REACTOME:R-HSA-186797] [PUBMED:15207811] [PUBMED:10508235] [PUBMED:9739761]
Signalling by NGF [NCBI:1269443] [REACTOME:R-HSA-166520]
Transmembrane transport of small molecules [NCBI:1269903] [REACTOME:R-HSA-382551]
Vasopressin regulates renal water homeostasis via Aquaporins [NCBI:1269946] [REACTOME:R-HSA-432040] [PUBMED:18566824] [PUBMED:15924268] [PUBMED:17222168] [PUBMED:11773613] [PUBMED:19096775]