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Genes
BRAF
Gene - BRAF
full name
B-Raf proto-oncogene, serine/threonine kinase
synonyms
B-RAF1, BRAF1, NS7, RAFB1, BRAF, ENSG00000157764
HGNC
HGNC:1097
Entrez Gene
Gene:673
ENSEMBL
ENSG00000157764
location
chr: 7
start: 140415749
stop: 140624564
strand: -
OMIM
OMIM:164757
: BRAF
(Autosomal recessive inheritance)
OMIM:211980
: Adenocarcinoma of lung, somatic
OMIM:115150
: Cardiofaciocutaneous syndrome
OMIM:613707
: LEOPARD syndrome 3
OMIM:613706
: Noonan syndrome 7
transcripts
NM_004333.4
pathways
ARMS-mediated activation
[NCBI:1269471]
[REACTOME:R-HSA-170984]
[PUBMED:9069267]
Activation of NMDA receptor upon glutamate binding and postsynaptic events
[NCBI:1268798]
[REACTOME:R-HSA-442755]
[PUBMED:18616423]
Acute myeloid leukemia
[NCBI:83117]
[KEGG:hsa05221]
[PUBMED:12951584]
[PUBMED:12563308]
[PUBMED:16352814]
[PUBMED:16236521]
[PUBMED:16146838]
[PUBMED:16642045]
[PUBMED:15625120]
[PUBMED:11721960]
[PUBMED:17554387]
[PUBMED:12468433]
Alcoholism
[NCBI:585563]
[KEGG:hsa05034]
[PUBMED:16764827]
[PUBMED:18616668]
[PUBMED:19077056]
[PUBMED:18991950]
[PUBMED:19756388]
[PUBMED:12068305]
[PUBMED:16102840]
[PUBMED:20947635]
[PUBMED:20729980]
[PUBMED:16278489]
[PUBMED:17270154]
[PUBMED:20626732]
[PUBMED:18310464]
[PUBMED:10774721]
[PUBMED:19342616]
[PUBMED:12605085]
[PUBMED:15500908]
[PUBMED:14729391]
[PUBMED:12085089]
[PUBMED:16776597]
Axon guidance
[NCBI:83065]
[KEGG:hsa04360]
[NCBI:1270303]
[REACTOME:R-HSA-422475]
[PUBMED:14682358]
[PUBMED:15084255]
[PUBMED:11687826]
[PUBMED:15818466]
[PUBMED:15363605]
[PUBMED:12471249]
[PUBMED:15630019]
[PUBMED:11891122]
[PUBMED:15960985]
[PUBMED:12677003]
Bladder cancer
[NCBI:83115]
[KEGG:hsa05219]
[PUBMED:15551095]
[PUBMED:15746962]
[PUBMED:11103787]
[PUBMED:16474624]
[PUBMED:17158541]
[PUBMED:12850530]
[PUBMED:17149381]
[PUBMED:16110317]
Breast cancer
[NCBI:1435207]
[KEGG:hsa05224]
[PUBMED:24649067]
[PUBMED:26040571]
[PUBMED:11879567]
[PUBMED:22722193]
[PUBMED:26028978]
[PUBMED:25013431]
[PUBMED:11737884]
[PUBMED:23702927]
[PUBMED:21076461]
[PUBMED:21898546]
[PUBMED:27390604]
[PUBMED:24291072]
[PUBMED:26968398]
[PUBMED:20087430]
[PUBMED:23000897]
[PUBMED:25544707]
[PUBMED:24596345]
[PUBMED:23988612]
[PUBMED:24111892]
[PUBMED:25907219]
[PUBMED:15343273]
[PUBMED:21965336]
[PUBMED:23881035]
[PUBMED:23196196]
[PUBMED:22178455]
[PUBMED:20436504]
[PUBMED:19088017]
[PUBMED:16113099]
[PUBMED:20971825]
CDC42 signaling events
[NCBI:137994]
[Pathway Interaction Database:cdc42_pathway]
[PUBMED:7629060]
[PUBMED:7652575]
[PUBMED:8653792]
[PUBMED:18448434]
[PUBMED:19822663]
[PUBMED:19454477]
[PUBMED:18662680]
[PUBMED:15882626]
[PUBMED:11948177]
[PUBMED:9860974]
[PUBMED:15225553]
[PUBMED:8643625]
[PUBMED:8107774]
[PUBMED:8670801]
[PUBMED:8034624]
[PUBMED:10934474]
[PUBMED:10734320]
[PUBMED:17522712]
[PUBMED:11525734]
[PUBMED:15649357]
[PUBMED:10473551]
[PUBMED:16157700]
[PUBMED:9822598]
[PUBMED:15723051]
[PUBMED:7600582]
[PUBMED:18319301]
[PUBMED:9042860]
[PUBMED:10613909]
[PUBMED:17580073]
[PUBMED:12745076]
[PUBMED:16253996]
[PUBMED:10840034]
[PUBMED:10360579]
[PUBMED:11907268]
[PUBMED:10934475]
[PUBMED:10219243]
[PUBMED:17038317]
[PUBMED:8910292]
[PUBMED:9403696]
[PUBMED:11285260]
[PUBMED:10995437]
[PUBMED:9368021]
[PUBMED:14970210]
[PUBMED:9694656]
[PUBMED:14505571]
[PUBMED:17115031]
[PUBMED:9317150]
[PUBMED:14653992]
[PUBMED:17081755]
[PUBMED:12676083]
[PUBMED:18216334]
[PUBMED:19826000]
[PUBMED:8702968]
[PUBMED:11304531]
[PUBMED:10973943]
[PUBMED:11309380]
[PUBMED:18586681]
[PUBMED:15479449]
[PUBMED:19097998]
[PUBMED:16892055]
[PUBMED:17244649]
[PUBMED:8625410]
[PUBMED:8497321]
[PUBMED:15485841]
[PUBMED:16407834]
[PUBMED:11804587]
[PUBMED:9867866]
[PUBMED:10747870]
[PUBMED:7600581]
[PUBMED:12610628]
[PUBMED:19435802]
[PUBMED:15572110]
[PUBMED:7592586]
[PUBMED:11696321]
[PUBMED:10559936]
CREB phosphorylation through the activation of Ras
[NCBI:1268801]
[REACTOME:R-HSA-442742]
[PUBMED:12819448]
Chemokine signaling pathway
[NCBI:99051]
[KEGG:hsa04062]
[PUBMED:17371236]
[PUBMED:19159344]
[PUBMED:17169327]
[PUBMED:10852130]
[PUBMED:9765254]
[PUBMED:15771581]
[PUBMED:14607270]
[PUBMED:18662984]
[PUBMED:12495636]
[PUBMED:15803148]
[PUBMED:15046611]
[PUBMED:12069927]
[PUBMED:18711432]
[PUBMED:17675482]
[PUBMED:16144840]
[PUBMED:17496928]
[PUBMED:17537990]
[PUBMED:11872087]
[PUBMED:12051620]
[PUBMED:14625285]
[PUBMED:8576262]
[PUBMED:11244042]
Chronic myeloid leukemia
[NCBI:83116]
[KEGG:hsa05220]
[PUBMED:22286129]
[PUBMED:12801837]
[PUBMED:11160144]
[PUBMED:15719031]
[PUBMED:10403855]
[PUBMED:9834202]
[PUBMED:11071626]
[PUBMED:12244301]
[PUBMED:15156182]
[PUBMED:16484590]
[PUBMED:14982876]
Colorectal cancer
[NCBI:83106]
[KEGG:hsa05210]
[PUBMED:15479695]
[PUBMED:11459867]
[PUBMED:9196022]
[PUBMED:11170304]
[PUBMED:12951588]
[PUBMED:15349822]
[PUBMED:15711891]
[PUBMED:16042571]
[PUBMED:15000146]
[PUBMED:12737309]
[PUBMED:10505543]
[PUBMED:11078609]
[PUBMED:11223406]
[PUBMED:16326109]
[PUBMED:16699851]
[PUBMED:11477132]
[PUBMED:12621137]
[PUBMED:15573119]
[PUBMED:16555243]
[PUBMED:15310786]
Cytokine Signaling in Immune system
[NCBI:1269310]
[REACTOME:R-HSA-1280215]
[PUBMED:12613569]
DAP12 interactions
[NCBI:1269283]
[REACTOME:R-HSA-2172127]
[PUBMED:19120482]
[PUBMED:17220916]
[PUBMED:9490415]
[PUBMED:18192027]
[PUBMED:15884055]
DAP12 signaling
[NCBI:1269284]
[REACTOME:R-HSA-2424491]
[PUBMED:15884055]
[PUBMED:17110943]
[PUBMED:17220916]
Developmental Biology
[NCBI:1270302]
[REACTOME:R-HSA-1266738]
Disease
[NCBI:1268854]
[REACTOME:R-HSA-1643685]
Diseases of signal transduction
[NCBI:1268855]
[REACTOME:R-HSA-5663202]
[PUBMED:12509752]
Dorso-ventral axis formation
[NCBI:114227]
[KEGG:hsa04320]
Downstream signal transduction
[NCBI:1269479]
[REACTOME:R-HSA-186763]
[PUBMED:10508235]
[PUBMED:9739761]
Downstream signaling in naive CD8+ T cells
[NCBI:138018]
[Pathway Interaction Database:cd8tcrdownstreampathway]
[PUBMED:293720]
[PUBMED:7935374]
[PUBMED:12065418]
[PUBMED:8566027]
[PUBMED:12917261]
[PUBMED:8394352]
[PUBMED:8441422]
[PUBMED:1386920]
[PUBMED:8617294]
[PUBMED:12732656]
[PUBMED:7889942]
[PUBMED:1737937]
[PUBMED:1381507]
[PUBMED:16210616]
[PUBMED:11927626]
[PUBMED:10477579]
[PUBMED:10206983]
[PUBMED:8376940]
[PUBMED:9395475]
[PUBMED:12972619]
[PUBMED:8394845]
[PUBMED:11485747]
[PUBMED:15814665]
[PUBMED:14645153]
[PUBMED:2119889]
[PUBMED:8208531]
[PUBMED:10970869]
[PUBMED:8612134]
[PUBMED:8623163]
[PUBMED:16237086]
[PUBMED:16585578]
[PUBMED:10544201]
[PUBMED:8397339]
[PUBMED:14605368]
[PUBMED:12560487]
[PUBMED:7982959]
EGFR tyrosine kinase inhibitor resistance
[NCBI:1404798]
[KEGG:hsa01521]
[PUBMED:16843264]
[PUBMED:23401451]
[PUBMED:20966921]
[PUBMED:24307395]
[PUBMED:22956644]
[PUBMED:25232485]
[PUBMED:24493829]
[PUBMED:23071030]
[PUBMED:18483355]
[PUBMED:24202392]
[PUBMED:19632948]
[PUBMED:23361103]
[PUBMED:26579470]
[PUBMED:22970367]
[PUBMED:23358468]
[PUBMED:17554333]
[PUBMED:25337673]
[PUBMED:22474259]
[PUBMED:20551942]
Endocrine resistance
[NCBI:1404799]
[KEGG:hsa01522]
[PUBMED:24415977]
[PUBMED:23625614]
[PUBMED:24841429]
[PUBMED:15613444]
[PUBMED:23714450]
[PUBMED:20960099]
[PUBMED:22771991]
[PUBMED:19701242]
[PUBMED:24289103]
[PUBMED:24130921]
[PUBMED:23344024]
[PUBMED:22015292]
[PUBMED:26122181]
[PUBMED:26473850]
[PUBMED:18804516]
[PUBMED:24565562]
[PUBMED:26849149]
[PUBMED:25907219]
[PUBMED:20887199]
Endometrial cancer
[NCBI:83109]
[KEGG:hsa05213]
[PUBMED:14747944]
[PUBMED:11431710]
[PUBMED:7585656]
[PUBMED:16508724]
[PUBMED:15284264]
[PUBMED:17028294]
[PUBMED:16248975]
[PUBMED:15947972]
ErbB signaling pathway
[NCBI:83049]
[KEGG:hsa04012]
[PUBMED:16377102]
[PUBMED:14967450]
[PUBMED:9642287]
[PUBMED:9872057]
[PUBMED:10880430]
[PUBMED:12851486]
[PUBMED:16729045]
[PUBMED:15863494]
[PUBMED:15864276]
[PUBMED:17000658]
[PUBMED:16729043]
[PUBMED:10490623]
[PUBMED:11252954]
[PUBMED:14744244]
[PUBMED:16829981]
ErbB1 downstream signaling
[NCBI:138057]
[Pathway Interaction Database:erbb1_downstream_pathway]
[PUBMED:1330321]
[PUBMED:7939666]
[PUBMED:9448004]
[PUBMED:3497813]
[PUBMED:7680434]
[PUBMED:18567582]
[PUBMED:12503606]
[PUBMED:12183455]
[PUBMED:8073291]
[PUBMED:17563371]
[PUBMED:8378775]
[PUBMED:19219045]
[PUBMED:1990291]
[PUBMED:15550174]
[PUBMED:16508002]
[PUBMED:17881733]
[PUBMED:11278353]
[PUBMED:9889102]
[PUBMED:14699061]
[PUBMED:8248196]
[PUBMED:8262053]
[PUBMED:11319218]
[PUBMED:19595761]
[PUBMED:17360704]
[PUBMED:15048123]
[PUBMED:19341767]
[PUBMED:9837959]
[PUBMED:14993287]
[PUBMED:19710016]
[PUBMED:18516090]
[PUBMED:9733714]
[PUBMED:8052307]
[PUBMED:10567369]
[PUBMED:9335504]
[PUBMED:9580112]
[PUBMED:11018520]
[PUBMED:10499589]
[PUBMED:19706684]
[PUBMED:8910287]
[PUBMED:10469645]
[PUBMED:11073940]
[PUBMED:9315636]
[PUBMED:2189103]
[PUBMED:14765121]
[PUBMED:14970219]
[PUBMED:8332195]
[PUBMED:16239230]
[PUBMED:8621729]
[PUBMED:11889038]
[PUBMED:11029289]
[PUBMED:11152283]
[PUBMED:8071311]
[PUBMED:12932319]
[PUBMED:19541618]
[PUBMED:2123453]
[PUBMED:9384584]
[PUBMED:8140422]
[PUBMED:10644690]
[PUBMED:18156174]
[PUBMED:15718470]
[PUBMED:12172553]
[PUBMED:10082559]
[PUBMED:17079732]
[PUBMED:12446727]
[PUBMED:9989263]
[PUBMED:12551925]
[PUBMED:10856237]
[PUBMED:8013650]
[PUBMED:7600581]
[PUBMED:8688081]
[PUBMED:8397445]
[PUBMED:16135787]
[PUBMED:7637810]
[PUBMED:9438848]
[PUBMED:12515821]
[PUBMED:12881422]
[PUBMED:9305638]
[PUBMED:15284024]
[PUBMED:3136398]
[PUBMED:10597268]
[PUBMED:10648629]
[PUBMED:9790194]
[PUBMED:9797479]
[PUBMED:16093354]
[PUBMED:7741752]
[PUBMED:10891480]
[PUBMED:17052213]
[PUBMED:8221888]
[PUBMED:9593664]
[PUBMED:16892053]
[PUBMED:8413226]
[PUBMED:9407138]
[PUBMED:9710644]
[PUBMED:8248197]
[PUBMED:12414794]
[PUBMED:1653949]
[PUBMED:12181570]
[PUBMED:9550702]
[PUBMED:12110590]
[PUBMED:10400627]
[PUBMED:9927426]
[PUBMED:12242303]
[PUBMED:10480933]
[PUBMED:9665134]
[PUBMED:11238956]
[PUBMED:16984645]
[PUBMED:7761091]
[PUBMED:17322878]
[PUBMED:12640115]
[PUBMED:14963038]
[PUBMED:17486115]
[PUBMED:8503013]
[PUBMED:16155590]
[PUBMED:16628218]
[PUBMED:1406636]
[PUBMED:9430728]
[PUBMED:19401591]
[PUBMED:17053785]
[PUBMED:7992057]
[PUBMED:14609431]
[PUBMED:9346240]
[PUBMED:8626780]
[PUBMED:8940018]
[PUBMED:12454019]
[PUBMED:10441128]
[PUBMED:14747473]
[PUBMED:11777939]
[PUBMED:8614832]
[PUBMED:8378774]
[PUBMED:19121340]
[PUBMED:18775988]
[PUBMED:15039778]
[PUBMED:9770464]
[PUBMED:10567531]
[PUBMED:8180183]
[PUBMED:10675331]
[PUBMED:1545823]
[PUBMED:7958858]
[PUBMED:11948693]
[PUBMED:2109185]
[PUBMED:8942998]
[PUBMED:1637333]
[PUBMED:14690430]
[PUBMED:11134016]
[PUBMED:12429840]
[PUBMED:8621573]
[PUBMED:7600582]
[PUBMED:8226933]
[PUBMED:10201527]
[PUBMED:12832467]
[PUBMED:3492494]
[PUBMED:15034142]
[PUBMED:9596579]
[PUBMED:7889942]
[PUBMED:8524316]
[PUBMED:7731720]
[PUBMED:8386592]
[PUBMED:16407412]
[PUBMED:6334806]
[PUBMED:11703925]
[PUBMED:11099046]
[PUBMED:7876145]
[PUBMED:14498832]
FCERI mediated MAPK activation
[NCBI:1269299]
[REACTOME:R-HSA-2871796]
[PUBMED:19290926]
[PUBMED:19909365]
[PUBMED:17122878]
Fc epsilon receptor (FCERI) signaling
[NCBI:1269298]
[REACTOME:R-HSA-2454202]
[PUBMED:15099567]
[PUBMED:21799019]
Focal adhesion
[NCBI:83067]
[KEGG:hsa04510]
[PUBMED:10698680]
[PUBMED:15459662]
[PUBMED:14756624]
[PUBMED:11573199]
[PUBMED:12640026]
[PUBMED:15179030]
[PUBMED:15108811]
[PUBMED:15053919]
[PUBMED:11082269]
[PUBMED:15034601]
[PUBMED:12235283]
[PUBMED:14519391]
[PUBMED:11146675]
[PUBMED:11229600]
[PUBMED:15688067]
[PUBMED:14744429]
[PUBMED:11882383]
FoxO signaling pathway
[NCBI:921162]
[KEGG:hsa04068]
[PUBMED:23325358]
[PUBMED:15005655]
[PUBMED:18951090]
[PUBMED:22761423]
[PUBMED:22902436]
[PUBMED:16288288]
[PUBMED:19701188]
[PUBMED:16964248]
[PUBMED:18045156]
[PUBMED:18403263]
[PUBMED:21613825]
[PUBMED:21440011]
[PUBMED:17470511]
[PUBMED:21238503]
[PUBMED:17522590]
[PUBMED:15084259]
[PUBMED:23801966]
[PUBMED:17569704]
[PUBMED:15516968]
Frs2-mediated activation
[NCBI:1269470]
[REACTOME:R-HSA-170968]
[PUBMED:9069267]
GRB2 events in EGFR signaling
[NCBI:1269382]
[REACTOME:R-HSA-179812]
[PUBMED:11706405]
[PUBMED:11498013]
Gastrin-CREB signalling pathway via PKC and MAPK
[NCBI:1269592]
[REACTOME:R-HSA-881907]
[PUBMED:10413847]
[PUBMED:7491953]
[PUBMED:17698287]
Glioma
[NCBI:83110]
[KEGG:hsa05214]
[PUBMED:11057895]
[PUBMED:11253051]
[PUBMED:12154354]
[PUBMED:12084351]
[PUBMED:15639402]
[PUBMED:9643506]
[PUBMED:16095998]
[PUBMED:12762887]
[PUBMED:16700615]
Hepatitis C
[NCBI:173973]
[KEGG:hsa05160]
[PUBMED:19708811]
[PUBMED:16314558]
[PUBMED:17467654]
[PUBMED:19515018]
[PUBMED:18514579]
[PUBMED:16107833]
[PUBMED:19074178]
[PUBMED:12691459]
[PUBMED:15302943]
[PUBMED:20537953]
[PUBMED:11991644]
[PUBMED:19148799]
[PUBMED:19187070]
[PUBMED:12655344]
IGF1R signaling cascade
[NCBI:1269618]
[REACTOME:R-HSA-2428924]
[PUBMED:17598937]
[PUBMED:20975071]
[PUBMED:22649417]
[PUBMED:21042815]
[PUBMED:18927274]
[PUBMED:20098959]
IRS-mediated signalling
[NCBI:1269431]
[REACTOME:R-HSA-112399]
IRS-related events triggered by IGF1R
[NCBI:1269620]
[REACTOME:R-HSA-2428928]
[PUBMED:17598937]
[PUBMED:20975071]
[PUBMED:22649417]
[PUBMED:18927274]
[PUBMED:21042815]
[PUBMED:20098959]
Immune System
[NCBI:1269170]
[REACTOME:R-HSA-168256]
Innate Immune System
[NCBI:1269203]
[REACTOME:R-HSA-168249]
Insulin receptor signalling cascade
[NCBI:1269429]
[REACTOME:R-HSA-74751]
[PUBMED:9677303]
[PUBMED:11282018]
Insulin signaling pathway
[NCBI:83090]
[KEGG:hsa04910]
[PUBMED:11742412]
[PUBMED:11343120]
[PUBMED:15733744]
[PUBMED:11282018]
[PUBMED:10196204]
[PUBMED:18291668]
[PUBMED:9609110]
[PUBMED:10567225]
[PUBMED:12791379]
[PUBMED:9748166]
[PUBMED:15624019]
[PUBMED:9445476]
[PUBMED:9346240]
[PUBMED:14635525]
[PUBMED:16288289]
[PUBMED:12867054]
[PUBMED:15229476]
[PUBMED:17344645]
[PUBMED:9609111]
Interleukin receptor SHC signaling
[NCBI:1269322]
[REACTOME:R-HSA-912526]
[PUBMED:8294403]
Interleukin-2 signaling
[NCBI:1269321]
[REACTOME:R-HSA-451927]
[PUBMED:17936914]
[PUBMED:18817510]
[PUBMED:19543225]
[PUBMED:18062768]
Interleukin-3, 5 and GM-CSF signaling
[NCBI:1269323]
[REACTOME:R-HSA-512988]
[PUBMED:10450743]
[PUBMED:9766809]
Long-term depression
[NCBI:83086]
[KEGG:hsa04730]
[PUBMED:9602501]
[PUBMED:9735948]
[PUBMED:14509570]
[PUBMED:11427694]
[PUBMED:12415297]
Long-term potentiation
[NCBI:83085]
[KEGG:hsa04720]
[PUBMED:9697848]
[PUBMED:15652868]
[PUBMED:15803158]
[PUBMED:11378299]
[PUBMED:10652548]
[PUBMED:15857686]
[PUBMED:14715912]
MAP2K and MAPK activation
[NCBI:1269287]
[REACTOME:R-HSA-5674135]
[PUBMED:21779496]
[PUBMED:20674547]
[PUBMED:22569528]
[PUBMED:22177953]
[PUBMED:19091303]
MAPK family signaling cascades
[NCBI:1269501]
[REACTOME:R-HSA-5683057]
[PUBMED:21167873]
[PUBMED:17161475]
[PUBMED:22535895]
[PUBMED:21372320]
MAPK signaling pathway
[NCBI:83048]
[KEGG:hsa04010]
[PUBMED:11749383]
[PUBMED:12566928]
[PUBMED:12849693]
[PUBMED:12676795]
[PUBMED:12947395]
[PUBMED:14597384]
[PUBMED:11369511]
[PUBMED:12191611]
[PUBMED:12390245]
MAPK1/MAPK3 signaling
[NCBI:1269502]
[REACTOME:R-HSA-5684996]
[PUBMED:25378393]
[PUBMED:18199641]
[PUBMED:17496909]
[PUBMED:21779496]
[PUBMED:15520807]
[PUBMED:16393692]
[PUBMED:19520853]
[PUBMED:17496910]
[PUBMED:22569528]
Melanoma
[NCBI:83114]
[KEGG:hsa05218]
[PUBMED:16822996]
[PUBMED:14695152]
[PUBMED:11224709]
[PUBMED:10843728]
[PUBMED:12894244]
[PUBMED:16899407]
[PUBMED:16001072]
[PUBMED:15721476]
[PUBMED:15557758]
[PUBMED:15009714]
[PUBMED:16001050]
[PUBMED:15841168]
[PUBMED:16750612]
NCAM signaling for neurite out-growth
[NCBI:1270312]
[REACTOME:R-HSA-375165]
[PUBMED:18760361]
[PUBMED:12587671]
[PUBMED:15662836]
[PUBMED:17975827]
[PUBMED:15153429]
[PUBMED:12700044]
NGF signalling via TRKA from the plasma membrane
[NCBI:1269460]
[REACTOME:R-HSA-187037]
[PUBMED:11520933]
[PUBMED:12676795]
[PUBMED:10851172]
[PUBMED:10579918]
Natural killer cell mediated cytotoxicity
[NCBI:83079]
[KEGG:hsa04650]
[PUBMED:12530970]
[PUBMED:15567854]
[PUBMED:8942070]
[PUBMED:11905813]
[PUBMED:9143705]
[PUBMED:9862693]
[PUBMED:11895890]
[PUBMED:12205470]
[PUBMED:11836514]
[PUBMED:15607806]
[PUBMED:16002670]
[PUBMED:15618404]
[PUBMED:11390470]
[PUBMED:11062493]
[PUBMED:14710949]
[PUBMED:12752668]
[PUBMED:15607802]
[PUBMED:16109839]
[PUBMED:12766758]
[PUBMED:16177799]
Negative feedback regulation of MAPK pathway
[NCBI:1269289]
[REACTOME:R-HSA-5674499]
[PUBMED:21177493]
[PUBMED:19933846]
[PUBMED:21613978]
[PUBMED:8626428]
[PUBMED:7478553]
[PUBMED:15664191]
[PUBMED:16508002]
[PUBMED:19219045]
[PUBMED:14654779]
Negative regulation of FGFR1 signaling
[NCBI:1269397]
[REACTOME:R-HSA-5654726]
[PUBMED:18452557]
[PUBMED:11997436]
[PUBMED:20940169]
[PUBMED:12815057]
Negative regulation of FGFR2 signaling
[NCBI:1269408]
[REACTOME:R-HSA-5654727]
[PUBMED:12815057]
[PUBMED:18452557]
[PUBMED:11997436]
[PUBMED:20940169]
Negative regulation of FGFR3 signaling
[NCBI:1269418]
[REACTOME:R-HSA-5654732]
[PUBMED:12815057]
[PUBMED:18452557]
[PUBMED:11997436]
[PUBMED:20940169]
Negative regulation of FGFR4 signaling
[NCBI:1269427]
[REACTOME:R-HSA-5654733]
[PUBMED:12815057]
[PUBMED:18452557]
[PUBMED:11997436]
[PUBMED:20940169]
Negative regulation of MAPK pathway
[NCBI:1269288]
[REACTOME:R-HSA-5675221]
[PUBMED:15664191]
[PUBMED:19219045]
[PUBMED:19158341]
[PUBMED:23443682]
[PUBMED:16892053]
[PUBMED:21779496]
[PUBMED:17496916]
Neuronal System
[NCBI:1268763]
[REACTOME:R-HSA-112316]
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
[NCBI:1268786]
[REACTOME:R-HSA-112314]
Neurotrophin signaling pathway
[NCBI:101143]
[KEGG:hsa04722]
[PUBMED:16699811]
[PUBMED:10812966]
[PUBMED:12676795]
[PUBMED:16939974]
[PUBMED:10851172]
[PUBMED:15499580]
[PUBMED:14704852]
[PUBMED:11399424]
[PUBMED:10764727]
[PUBMED:10985348]
[PUBMED:16856873]
[PUBMED:11529497]
Non-small cell lung cancer
[NCBI:83119]
[KEGG:hsa05223]
[PUBMED:11895903]
[PUBMED:21753699]
[PUBMED:23733083]
[PUBMED:11902573]
[PUBMED:19629074]
[PUBMED:12867060]
[PUBMED:22154278]
[PUBMED:10944551]
[PUBMED:16112428]
[PUBMED:15942304]
[PUBMED:12407699]
[PUBMED:15948711]
[PUBMED:18593892]
[PUBMED:23201355]
[PUBMED:21855164]
[PUBMED:12379883]
[PUBMED:17625570]
[PUBMED:12741677]
[PUBMED:22736493]
[PUBMED:21850578]
[PUBMED:16870043]
[PUBMED:16189154]
Oncogenic MAPK signaling
[NCBI:1457781]
[REACTOME:R-HSA-6802957]
[PUBMED:25907612]
[PUBMED:24651010]
[PUBMED:24202393]
[PUBMED:25435214]
[PUBMED:21993244]
[PUBMED:24814062]
[PUBMED:22589270]
Pancreatic cancer
[NCBI:83108]
[KEGG:hsa05212]
[PUBMED:12079267]
[PUBMED:14967450]
[PUBMED:15774796]
[PUBMED:10740269]
[PUBMED:12946833]
[PUBMED:16702400]
[PUBMED:14586404]
[PUBMED:15823750]
[PUBMED:12648469]
[PUBMED:11407945]
[PUBMED:12459728]
[PUBMED:14580692]
[PUBMED:11707511]
[PUBMED:12545153]
Paradoxical activation of RAF signaling by kinase inactive BRAF
[NCBI:1457785]
[REACTOME:R-HSA-6802955]
[PUBMED:25435214]
[PUBMED:20674547]
[PUBMED:24957944]
[PUBMED:23352452]
[PUBMED:20130576]
[PUBMED:23680146]
[PUBMED:16364920]
[PUBMED:25907612]
[PUBMED:15035987]
[PUBMED:20179705]
[PUBMED:19727074]
[PUBMED:20141835]
[PUBMED:22510884]
Pathways in cancer
[NCBI:83105]
[KEGG:hsa05200]
[PUBMED:12244301]
[PUBMED:15156182]
[PUBMED:16899407]
[PUBMED:12621137]
[PUBMED:21193867]
[PUBMED:16001072]
[PUBMED:11707511]
[PUBMED:11253051]
[PUBMED:11071626]
[PUBMED:17251915]
[PUBMED:11736900]
[PUBMED:16557281]
[PUBMED:16699851]
[PUBMED:16189702]
[PUBMED:11902573]
[PUBMED:16555243]
[PUBMED:8069858]
[PUBMED:15310786]
[PUBMED:9834202]
[PUBMED:16700615]
[PUBMED:12545153]
[PUBMED:15656799]
[PUBMED:12154354]
[PUBMED:11895903]
[PUBMED:11527574]
[PUBMED:16326109]
[PUBMED:16339096]
[PUBMED:11160144]
[PUBMED:15724144]
[PUBMED:12951584]
[PUBMED:10647931]
[PUBMED:16881963]
[PUBMED:15557758]
[PUBMED:11477132]
[PUBMED:15721476]
[PUBMED:15625120]
[PUBMED:16236521]
[PUBMED:14967450]
[PUBMED:15942304]
[PUBMED:17287871]
[PUBMED:14634372]
[PUBMED:15573119]
[PUBMED:15009714]
[PUBMED:16112428]
[PUBMED:15611513]
[PUBMED:16001050]
[PUBMED:15349822]
[PUBMED:16551846]
[PUBMED:15978322]
[PUBMED:15774796]
[PUBMED:16352814]
[PUBMED:12951588]
[PUBMED:10944551]
[PUBMED:10740269]
[PUBMED:15639402]
[PUBMED:12407699]
[PUBMED:11130178]
[PUBMED:15109562]
[PUBMED:11170304]
[PUBMED:11276000]
[PUBMED:9643506]
[PUBMED:16248975]
[PUBMED:16242838]
[PUBMED:12946833]
[PUBMED:11559746]
[PUBMED:9196022]
[PUBMED:12079267]
[PUBMED:15468170]
[PUBMED:16064138]
[PUBMED:14580692]
[PUBMED:15082523]
[PUBMED:15551095]
[PUBMED:17062879]
[PUBMED:17211469]
[PUBMED:11720739]
[PUBMED:12588368]
[PUBMED:11057895]
[PUBMED:9422516]
[PUBMED:12894244]
[PUBMED:15479695]
[PUBMED:16189154]
[PUBMED:12878745]
[PUBMED:11900250]
[PUBMED:11103787]
[PUBMED:15122209]
[PUBMED:12711111]
[PUBMED:12243753]
[PUBMED:16306523]
[PUBMED:16702400]
[PUBMED:15270885]
[PUBMED:14685170]
[PUBMED:14586404]
[PUBMED:11078609]
[PUBMED:15284264]
[PUBMED:10505543]
[PUBMED:11223406]
[PUBMED:14982876]
[PUBMED:12648469]
[PUBMED:12867060]
[PUBMED:15711891]
[PUBMED:12094241]
[PUBMED:16642045]
[PUBMED:11463388]
[PUBMED:12762887]
[PUBMED:15746962]
[PUBMED:15823750]
[PUBMED:16750612]
[PUBMED:16484590]
[PUBMED:11459867]
[PUBMED:16146838]
[PUBMED:14556242]
[PUBMED:15947972]
[PUBMED:12563308]
[PUBMED:16946003]
[PUBMED:15948971]
[PUBMED:11407945]
[PUBMED:12737309]
[PUBMED:16095998]
[PUBMED:12351585]
[PUBMED:24508914]
[PUBMED:12084351]
[PUBMED:11807782]
[PUBMED:14695152]
[PUBMED:10453277]
[PUBMED:17554387]
[PUBMED:15841168]
[PUBMED:12616528]
[PUBMED:10403855]
[PUBMED:16054233]
[PUBMED:16474624]
[PUBMED:16822996]
[PUBMED:17028294]
[PUBMED:11224709]
[PUBMED:11750244]
[PUBMED:11905738]
[PUBMED:15719031]
[PUBMED:10843728]
[PUBMED:16110317]
[PUBMED:11721960]
[PUBMED:12741677]
[PUBMED:7585656]
[PUBMED:12801837]
[PUBMED:16551847]
[PUBMED:12459728]
[PUBMED:11431710]
[PUBMED:12468433]
[PUBMED:11165748]
[PUBMED:16042571]
[PUBMED:16508724]
[PUBMED:15000146]
[PUBMED:17149381]
[PUBMED:15948711]
[PUBMED:14747944]
[PUBMED:14737121]
[PUBMED:12379883]
[PUBMED:17158541]
[PUBMED:12850530]
[PUBMED:10835690]
[PUBMED:16870043]
Post NMDA receptor activation events
[NCBI:1268800]
[REACTOME:R-HSA-438064]
[PUBMED:18616423]
Progesterone-mediated oocyte maturation
[NCBI:119304]
[KEGG:hsa04914]
[PUBMED:10497333]
[PUBMED:12084906]
[PUBMED:12045215]
[PUBMED:11063930]
[PUBMED:12477927]
[PUBMED:11148128]
[PUBMED:11730319]
[PUBMED:12374568]
Prolonged ERK activation events
[NCBI:1269469]
[REACTOME:R-HSA-169893]
[PUBMED:12765839]
[PUBMED:9069267]
Prostate cancer
[NCBI:83111]
[KEGG:hsa05215]
[PUBMED:12878745]
[PUBMED:11900250]
[PUBMED:11527574]
[PUBMED:11750244]
[PUBMED:16551847]
[PUBMED:10835690]
[PUBMED:8069858]
[PUBMED:15724144]
[PUBMED:10453277]
[PUBMED:15082523]
[PUBMED:9422516]
Proteoglycans in cancer
[NCBI:782000]
[KEGG:hsa05205]
[PUBMED:19433454]
[PUBMED:20655987]
[PUBMED:18798267]
[PUBMED:10633082]
[PUBMED:10687947]
[PUBMED:22735579]
[PUBMED:24412155]
[PUBMED:9346940]
[PUBMED:22087031]
[PUBMED:22194599]
[PUBMED:14711376]
[PUBMED:19255147]
[PUBMED:15655247]
[PUBMED:11717317]
[PUBMED:17971838]
[PUBMED:18413366]
[PUBMED:20974860]
[PUBMED:11830493]
[PUBMED:23058688]
[PUBMED:18450475]
[PUBMED:12748184]
[PUBMED:19733083]
[PUBMED:18812315]
[PUBMED:12509413]
[PUBMED:21155971]
[PUBMED:11931647]
[PUBMED:18949819]
[PUBMED:12729888]
[PUBMED:15994311]
[PUBMED:23305321]
[PUBMED:18505598]
[PUBMED:22563565]
[PUBMED:22033227]
RAF activation
[NCBI:1269286]
[REACTOME:R-HSA-5673000]
[PUBMED:9689060]
[PUBMED:16364920]
[PUBMED:23993095]
[PUBMED:17555829]
[PUBMED:12865432]
[PUBMED:11782426]
[PUBMED:11296227]
[PUBMED:12068308]
[PUBMED:11447113]
[PUBMED:11950876]
[PUBMED:21779496]
[PUBMED:20141835]
[PUBMED:11296228]
[PUBMED:15710605]
[PUBMED:2993863]
[PUBMED:11821947]
[PUBMED:24937142]
[PUBMED:11579234]
RAF/MAP kinase cascade
[NCBI:1269285]
[REACTOME:R-HSA-5673001]
[PUBMED:21167873]
[PUBMED:24937142]
[PUBMED:20674547]
[PUBMED:17496910]
[PUBMED:22177953]
[PUBMED:17496919]
[PUBMED:22569528]
[PUBMED:22535895]
[PUBMED:12068308]
[PUBMED:17496923]
[PUBMED:19091303]
[PUBMED:21372320]
[PUBMED:21388974]
[PUBMED:15520807]
RET signaling
[NCBI:1427866]
[REACTOME:R-HSA-8853659]
[PUBMED:15013219]
[PUBMED:17036197]
Rap1 signaling pathway
[NCBI:868086]
[KEGG:hsa04015]
[PUBMED:17624944]
[PUBMED:12351703]
[PUBMED:10579920]
[PUBMED:19159611]
[PUBMED:18363565]
[PUBMED:12765839]
[PUBMED:12508104]
[PUBMED:11331911]
[PUBMED:17182900]
[PUBMED:15803158]
[PUBMED:19615876]
[PUBMED:21402149]
[PUBMED:17624948]
[PUBMED:17383543]
[PUBMED:14607972]
[PUBMED:15780587]
[PUBMED:19710505]
Ras signaling in the CD4+ TCR pathway
[NCBI:137921]
[Pathway Interaction Database:tcrraspathway]
[PUBMED:12917261]
[PUBMED:1386920]
[PUBMED:1381507]
[PUBMED:7889942]
[PUBMED:8394352]
[PUBMED:8631303]
[PUBMED:10206983]
[PUBMED:12972619]
[PUBMED:8394845]
[PUBMED:2119889]
[PUBMED:8208531]
[PUBMED:7935374]
Regulation of actin cytoskeleton
[NCBI:83089]
[KEGG:hsa04810]
[PUBMED:11152757]
[PUBMED:11082272]
[PUBMED:10574699]
[PUBMED:11082269]
[PUBMED:14657486]
[PUBMED:14744429]
[PUBMED:12700767]
Renal cell carcinoma
[NCBI:83107]
[KEGG:hsa05211]
[PUBMED:12351585]
[PUBMED:17211469]
[PUBMED:16339096]
[PUBMED:17287871]
[PUBMED:14634372]
[PUBMED:15611513]
[PUBMED:14685170]
[PUBMED:15122209]
SHC1 events in EGFR signaling
[NCBI:1269383]
[REACTOME:R-HSA-180336]
[PUBMED:11498013]
[PUBMED:8755247]
SOS-mediated signalling
[NCBI:1269440]
[REACTOME:R-HSA-112412]
Serotonergic synapse
[NCBI:525336]
[KEGG:hsa04726]
[PUBMED:9658404]
[PUBMED:15034221]
[PUBMED:11043573]
[PUBMED:9651340]
[PUBMED:9542727]
[PUBMED:18676031]
[PUBMED:12543273]
[PUBMED:15710402]
[PUBMED:16826372]
[PUBMED:19545642]
[PUBMED:11916537]
[PUBMED:11701344]
[PUBMED:12676358]
[PUBMED:20561690]
[PUBMED:16896947]
Signal Transduction
[NCBI:1269379]
[REACTOME:R-HSA-162582]
[PUBMED:17604717]
[PUBMED:19648010]
[PUBMED:16260143]
[PUBMED:11742412]
[PUBMED:19536106]
[PUBMED:15863030]
[PUBMED:19379690]
[PUBMED:19458711]
[PUBMED:19935667]
[PUBMED:21252999]
[PUBMED:15520807]
[PUBMED:17496910]
[PUBMED:15450248]
[PUBMED:18043707]
[PUBMED:16939974]
[PUBMED:19762341]
[PUBMED:18483217]
[PUBMED:17084981]
[PUBMED:21781017]
[PUBMED:19619488]
Signaling by BRAF and RAF fusions
[NCBI:1457786]
[REACTOME:R-HSA-6802952]
[PUBMED:18974108]
[PUBMED:24135138]
[PUBMED:22745804]
[PUBMED:25907612]
[PUBMED:20526349]
[PUBMED:15630448]
[PUBMED:25204415]
[PUBMED:24345920]
[PUBMED:21424530]
[PUBMED:23583981]
Signaling by EGFR
[NCBI:1269380]
[REACTOME:R-HSA-177929]
[PUBMED:10459005]
[PUBMED:10404636]
[PUBMED:12297041]
[PUBMED:15142631]
Signaling by FGFR
[NCBI:1269386]
[REACTOME:R-HSA-190236]
[PUBMED:15863038]
[PUBMED:12080084]
[PUBMED:20602996]
[PUBMED:15863030]
[PUBMED:15567848]
[PUBMED:7917292]
[PUBMED:19247306]
[PUBMED:16597617]
Signaling by FGFR1
[NCBI:1269387]
[REACTOME:R-HSA-5654736]
[PUBMED:16597617]
[PUBMED:19247306]
[PUBMED:12080084]
[PUBMED:15863038]
[PUBMED:15567848]
[PUBMED:20602996]
[PUBMED:7917292]
[PUBMED:15863030]
Signaling by FGFR2
[NCBI:1269399]
[REACTOME:R-HSA-5654738]
[PUBMED:19247306]
[PUBMED:16597617]
[PUBMED:15863038]
[PUBMED:12080084]
[PUBMED:15863030]
[PUBMED:20602996]
[PUBMED:15567848]
[PUBMED:7917292]
Signaling by FGFR3
[NCBI:1269409]
[REACTOME:R-HSA-5654741]
[PUBMED:16597617]
[PUBMED:19247306]
[PUBMED:15863038]
[PUBMED:12080084]
[PUBMED:20602996]
[PUBMED:15567848]
[PUBMED:7917292]
[PUBMED:15863030]
Signaling by FGFR4
[NCBI:1269419]
[REACTOME:R-HSA-5654743]
[PUBMED:15863038]
[PUBMED:12080084]
[PUBMED:15567848]
[PUBMED:20602996]
[PUBMED:7917292]
[PUBMED:15863030]
[PUBMED:19247306]
[PUBMED:16597617]
Signaling by GPCR
[NCBI:1269543]
[REACTOME:R-HSA-372790]
[PUBMED:16902930]
[PUBMED:10202136]
[PUBMED:18043707]
Signaling by Insulin receptor
[NCBI:1269428]
[REACTOME:R-HSA-74752]
[PUBMED:8276779]
Signaling by Interleukins
[NCBI:1269318]
[REACTOME:R-HSA-449147]
[PUBMED:19302047]
[PUBMED:12445398]
Signaling by Leptin
[NCBI:1269632]
[REACTOME:R-HSA-2586552]
[PUBMED:22211890]
[PUBMED:23562747]
[PUBMED:20600241]
[PUBMED:21622208]
[PUBMED:23579596]
[PUBMED:22458591]
[PUBMED:21489811]
[PUBMED:19724019]
[PUBMED:21331644]
[PUBMED:22448029]
[PUBMED:21147620]
[PUBMED:20198122]
[PUBMED:21677426]
[PUBMED:20029269]
[PUBMED:22249808]
[PUBMED:22991412]
[PUBMED:21527729]
[PUBMED:17937601]
[PUBMED:20553370]
[PUBMED:21713385]
[PUBMED:23565489]
[PUBMED:22289780]
Signaling by PDGF
[NCBI:1269478]
[REACTOME:R-HSA-186797]
[PUBMED:15207811]
[PUBMED:10508235]
[PUBMED:9739761]
Signaling by RAS mutants
[NCBI:1457782]
[REACTOME:R-HSA-6802949]
[PUBMED:21993244]
[PUBMED:22589270]
[PUBMED:24651010]
Signaling by SCF-KIT
[NCBI:1269487]
[REACTOME:R-HSA-1433557]
[PUBMED:17350321]
[PUBMED:16483568]
[PUBMED:7688988]
[PUBMED:19540337]
[PUBMED:16475976]
[PUBMED:15526160]
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
[NCBI:1269617]
[REACTOME:R-HSA-2404192]
[PUBMED:21042815]
[PUBMED:18927274]
[PUBMED:20098959]
[PUBMED:17598937]
[PUBMED:20975071]
[PUBMED:22044904]
[PUBMED:22649417]
Signaling by VEGF
[NCBI:1269480]
[REACTOME:R-HSA-194138]
[PUBMED:15585754]
[PUBMED:13678960]
[PUBMED:16336962]
[PUBMED:16835467]
Signaling by high-kinase activity BRAF mutants
[NCBI:1457783]
[REACTOME:R-HSA-6802948]
[PUBMED:16702958]
[PUBMED:21190184]
[PUBMED:23352452]
[PUBMED:16364920]
[PUBMED:22113612]
[PUBMED:12068308]
[PUBMED:15035987]
[PUBMED:22510884]
[PUBMED:25435214]
[PUBMED:24202393]
Signaling by moderate kinase activity BRAF mutants
[NCBI:1457784]
[REACTOME:R-HSA-6802946]
[PUBMED:25907612]
[PUBMED:15035987]
[PUBMED:24202393]
[PUBMED:22510884]
[PUBMED:25355519]
[PUBMED:23352452]
Signaling events mediated by focal adhesion kinase
[NCBI:169348]
[Pathway Interaction Database:fak_pathway]
[PUBMED:18793427]
[PUBMED:15340073]
[PUBMED:16054026]
[PUBMED:12932330]
[PUBMED:20038548]
[PUBMED:7542255]
[PUBMED:8939916]
[PUBMED:16000375]
[PUBMED:10856236]
[PUBMED:17164291]
[PUBMED:9148935]
[PUBMED:10893408]
[PUBMED:10512882]
[PUBMED:11839772]
[PUBMED:11553710]
[PUBMED:7566154]
[PUBMED:20018869]
[PUBMED:12839996]
[PUBMED:11799111]
[PUBMED:16308318]
[PUBMED:11331870]
[PUBMED:12681445]
[PUBMED:11369769]
[PUBMED:11739801]
[PUBMED:9860979]
[PUBMED:8947559]
[PUBMED:11017882]
[PUBMED:7509446]
[PUBMED:10791986]
[PUBMED:9128257]
[PUBMED:19297531]
[PUBMED:17325207]
[PUBMED:17093062]
[PUBMED:10593973]
[PUBMED:20308429]
[PUBMED:8922390]
[PUBMED:19776348]
[PUBMED:9374537]
[PUBMED:10976102]
[PUBMED:10373530]
[PUBMED:19883375]
[PUBMED:10430888]
[PUBMED:12820964]
[PUBMED:9425168]
[PUBMED:14743221]
[PUBMED:18854312]
[PUBMED:12952943]
[PUBMED:15962308]
[PUBMED:11927607]
[PUBMED:15657076]
[PUBMED:15039571]
[PUBMED:18303050]
[PUBMED:11799401]
[PUBMED:15247219]
[PUBMED:12702722]
[PUBMED:10998418]
[PUBMED:7615549]
[PUBMED:18195107]
[PUBMED:9032297]
[PUBMED:10873807]
[PUBMED:10777511]
[PUBMED:12502711]
[PUBMED:9566877]
[PUBMED:8649427]
[PUBMED:19473962]
[PUBMED:9808620]
[PUBMED:15914540]
[PUBMED:1385445]
[PUBMED:18223254]
[PUBMED:11909938]
[PUBMED:15166238]
[PUBMED:7622520]
[PUBMED:8824286]
[PUBMED:8662921]
[PUBMED:8707856]
[PUBMED:10330411]
[PUBMED:10446223]
[PUBMED:20150423]
[PUBMED:11604500]
[PUBMED:9234699]
[PUBMED:18773890]
[PUBMED:18757826]
[PUBMED:9864370]
[PUBMED:7983066]
[PUBMED:18322799]
[PUBMED:12006652]
[PUBMED:16461767]
[PUBMED:10385525]
[PUBMED:14676198]
[PUBMED:9858476]
[PUBMED:18070912]
[PUBMED:11058585]
[PUBMED:12890755]
[PUBMED:9184223]
[PUBMED:12058076]
[PUBMED:12226752]
[PUBMED:19435801]
[PUBMED:10212207]
[PUBMED:10521463]
[PUBMED:16159962]
[PUBMED:7579684]
[PUBMED:18362184]
[PUBMED:7997267]
[PUBMED:8816475]
[PUBMED:11279163]
[PUBMED:7537852]
[PUBMED:11418135]
[PUBMED:12167697]
[PUBMED:12615911]
[PUBMED:12876277]
Signalling by NGF
[NCBI:1269443]
[REACTOME:R-HSA-166520]
Signalling to ERKs
[NCBI:1269464]
[REACTOME:R-HSA-187687]
[PUBMED:10508738]
Signalling to RAS
[NCBI:1269465]
[REACTOME:R-HSA-167044]
[PUBMED:11520933]
Signalling to p38 via RIT and RIN
[NCBI:1269468]
[REACTOME:R-HSA-187706]
[PUBMED:10712923]
Spry regulation of FGF signaling
[NCBI:1269398]
[REACTOME:R-HSA-1295596]
[PUBMED:9458049]
[PUBMED:16893902]
[PUBMED:19690147]
[PUBMED:19570949]
Thyroid cancer
[NCBI:83112]
[KEGG:hsa05216]
[PUBMED:16189702]
[PUBMED:17062879]
[PUBMED:16557281]
[PUBMED:16242838]
[PUBMED:12094241]
[PUBMED:16551846]
[PUBMED:16946003]
[PUBMED:11165748]
Transmission across Chemical Synapses
[NCBI:1268766]
[REACTOME:R-HSA-112315]
Trk receptor signaling mediated by the MAPK pathway
[NCBI:138044]
[Pathway Interaction Database:mapktrkpathway]
[PUBMED:15632082]
[PUBMED:11050086]
[PUBMED:9687510]
[PUBMED:17003042]
[PUBMED:7889942]
[PUBMED:11150318]
[PUBMED:11331872]
[PUBMED:8387505]
[PUBMED:1386920]
[PUBMED:8394352]
[PUBMED:11278445]
[PUBMED:15917464]
[PUBMED:9560161]
[PUBMED:11073940]
[PUBMED:12826611]
[PUBMED:16157584]
[PUBMED:15024033]
[PUBMED:9528766]
[PUBMED:12011113]
[PUBMED:10330161]
[PUBMED:11544482]
[PUBMED:12367506]
[PUBMED:12917366]
VEGFA-VEGFR2 Pathway
[NCBI:1269483]
[REACTOME:R-HSA-4420097]
[PUBMED:17344076]
[PUBMED:16633338]
[PUBMED:19230644]
[PUBMED:13678960]
VEGFR2 mediated cell proliferation
[NCBI:1269485]
[REACTOME:R-HSA-5218921]
[PUBMED:22866201]
[PUBMED:22180219]
[PUBMED:22762016]
Vascular smooth muscle contraction
[NCBI:96530]
[KEGG:hsa04270]
[PUBMED:16870827]
[PUBMED:10911373]
[PUBMED:11679404]
[PUBMED:16339747]
[PUBMED:10221985]
[PUBMED:12689814]
[PUBMED:11165670]
[PUBMED:18552454]
[PUBMED:12060106]
[PUBMED:9458738]
[PUBMED:15725705]
[PUBMED:18040024]
[PUBMED:12693609]
[PUBMED:11773611]
[PUBMED:17158339]
[PUBMED:17458653]
[PUBMED:15026027]
[PUBMED:19120701]
[PUBMED:15269340]
[PUBMED:18703404]
[PUBMED:11709400]
[PUBMED:17200683]
cAMP signaling pathway
[NCBI:1017634]
[KEGG:hsa04024]
[PUBMED:10880354]
[PUBMED:9204709]
[PUBMED:21693691]
[PUBMED:24062645]
[PUBMED:24450633]
[PUBMED:21346730]
[PUBMED:24613710]
[PUBMED:21744067]
[PUBMED:22082266]
[PUBMED:16460276]
[PUBMED:18176800]
[PUBMED:14715909]
[PUBMED:7688165]
[PUBMED:24281338]
[PUBMED:11117527]
[PUBMED:16765984]
[PUBMED:18323530]
[PUBMED:18064650]
[PUBMED:21852968]
[PUBMED:11493633]
[PUBMED:21212391]
[PUBMED:15142747]
[PUBMED:17077866]
[PUBMED:19460777]
[PUBMED:19874988]
[PUBMED:16571352]
[PUBMED:22022314]
mTOR signaling pathway
[NCBI:83059]
[KEGG:hsa04150]
[NCBI:138001]
[Pathway Interaction Database:mtor_4pathway]
[PUBMED:17277771]
[PUBMED:15341740]
[PUBMED:12172553]
[PUBMED:15718470]
[PUBMED:14651849]
[PUBMED:15268862]
[PUBMED:15306821]
[PUBMED:26046644]
[PUBMED:12869586]
[PUBMED:24556838]
[PUBMED:17928295]
[PUBMED:9427642]
[PUBMED:18046414]
[PUBMED:12912918]
[PUBMED:16286006]
[PUBMED:26658722]
[PUBMED:24842496]
[PUBMED:23465396]
[PUBMED:17709744]
[PUBMED:17599906]
[PUBMED:16919458]
[PUBMED:10364159]
[PUBMED:15342917]
[PUBMED:11500364]
[PUBMED:19812304]
[PUBMED:12482958]
[PUBMED:11729323]
[PUBMED:16962653]
[PUBMED:18952604]
[PUBMED:9465032]
[PUBMED:1496022]
[PUBMED:10567431]
[PUBMED:19114562]
[PUBMED:17510057]
[PUBMED:18604198]
[PUBMED:15545625]
[PUBMED:11914378]
[PUBMED:17461779]
[PUBMED:9445476]
[PUBMED:18497260]
[PUBMED:12604610]
[PUBMED:15071500]
[PUBMED:18925875]
[PUBMED:12906785]
[PUBMED:11287630]
[PUBMED:15004009]
[PUBMED:16756488]
[PUBMED:17043309]
[PUBMED:18198340]
[PUBMED:12820960]
[PUBMED:12747827]
[PUBMED:17053147]
[PUBMED:15851026]
[PUBMED:15467718]
[PUBMED:18762023]
[PUBMED:25242279]
[PUBMED:24698685]
[PUBMED:11175345]
[PUBMED:27304501]
[PUBMED:18411301]
[PUBMED:11500365]
[PUBMED:17693255]
[PUBMED:23694989]
[PUBMED:12231510]
[PUBMED:19446321]
[PUBMED:11418588]
[PUBMED:19258318]
[PUBMED:18439900]
[PUBMED:19225151]
[PUBMED:26185979]
[PUBMED:10357815]
[PUBMED:26269525]
[PUBMED:23421405]
[PUBMED:9271440]
[PUBMED:16915281]
[PUBMED:17141160]
[PUBMED:15249583]
[PUBMED:12912989]
[PUBMED:27027448]
[PUBMED:18423201]
[PUBMED:19211835]
[PUBMED:9204908]
[PUBMED:26700098]
[PUBMED:18566587]
[PUBMED:17386266]