full name
lysine methyltransferase 2C

synonyms
HALR, MLL3, KMT2C, ENSG00000055609

HGNC
HGNC:13726

Entrez Gene
Gene:58508

ENSEMBL
ENSG00000055609

location
chr: 7
start: 151832010
stop: 152133090
strand: -

OMIM
OMIM:606833: KMT2C
OMIM:617768: Kleefstra syndrome 2

transcripts
NM_170606.2

pathways
Activation of HOX genes during differentiation [NCBI:1339139] [REACTOME:R-HSA-5619507] [PUBMED:19923920] [PUBMED:25804734] [PUBMED:23973942] [PUBMED:23650639] [PUBMED:20435029] [PUBMED:24529385]
Activation of anterior HOX genes in hindbrain development during early embryogenesis [NCBI:1339140] [REACTOME:R-HSA-5617472] [PUBMED:19575673] [PUBMED:23973942] [PUBMED:18394579] [PUBMED:24529385] [PUBMED:24115586] [PUBMED:18412118] [PUBMED:19651303] [PUBMED:25804734] [PUBMED:22770981] [PUBMED:19923920] [PUBMED:16155570] [PUBMED:18816852] [PUBMED:25560970] [PUBMED:10068641] [PUBMED:10662633] [PUBMED:20435029] [PUBMED:17368312] [PUBMED:21497760] [PUBMED:10668974]
Chromatin modifying enzymes [NCBI:1270434] [REACTOME:R-HSA-3247509]
Chromatin organization [NCBI:1270433] [REACTOME:R-HSA-4839726] [PUBMED:21342762] [PUBMED:15598472]
Developmental Biology [NCBI:1270302] [REACTOME:R-HSA-1266738]
Lysine degradation [NCBI:82956] [KEGG:hsa00310] [PUBMED:11802770] [PUBMED:1682209]
PKMTs methylate histone lysines [NCBI:1270438] [REACTOME:R-HSA-3214841] [PUBMED:11893494] [PUBMED:19721445]