full name
GATA binding protein 4

synonyms
ASD2, VSD1, GATA4, ENSG00000136574

HGNC
HGNC:4173

Entrez Gene
Gene:2626

ENSEMBL
ENSG00000136574

location
chr: 8
start: 11534433
stop: 11617510
strand: +

OMIM
OMIM:600576: GATA4 (Autosomal dominant inheritance)
OMIM:615542: ?Testicular anomalies with or without congenital heart disease
OMIM:607941: Atrial septal defect 2
OMIM:614430: Atrioventricular septal defect 4
OMIM:187500: Tetralogy of Fallot
OMIM:614429: Ventricular septal defect 1

transcripts
NM_002052.3

pathways
Cardiac conduction [NCBI:1339115] [REACTOME:R-HSA-5576891] [PUBMED:19808464] [PUBMED:26140724] [PUBMED:21357845]
Factors involved in megakaryocyte development and platelet production [NCBI:1269377] [REACTOME:R-HSA-983231] [PUBMED:16856888] [PUBMED:17635743] [PUBMED:17934486]
Gene Expression [NCBI:1269649] [REACTOME:R-HSA-74160]
Generic Transcription Pathway [NCBI:1269650] [REACTOME:R-HSA-212436] [PUBMED:15175151] [PUBMED:14744435] [PUBMED:15680972] [PUBMED:11395415] [PUBMED:15896744] [PUBMED:10235266] [PUBMED:14986688] [PUBMED:12023297] [PUBMED:15680973] [PUBMED:16751179] [PUBMED:11861166] [PUBMED:16429119] [PUBMED:16719718] [PUBMED:16921404] [PUBMED:15690163]
Hemostasis [NCBI:1269340] [REACTOME:R-HSA-109582]
Incretin synthesis, secretion, and inactivation [NCBI:1268750] [REACTOME:R-HSA-400508] [PUBMED:19074620] [PUBMED:17498508] [PUBMED:17263764]
Metabolism of proteins [NCBI:1268677] [REACTOME:R-HSA-392499]
Muscle contraction [NCBI:1269868] [REACTOME:R-HSA-397014]
Notch-mediated HES/HEY network [NCBI:169347] [Pathway Interaction Database:hes_heypathway] [PUBMED:15546612] [PUBMED:11038350] [PUBMED:12065598] [PUBMED:11741889] [PUBMED:10851137] [PUBMED:10205173] [PUBMED:10747963] [PUBMED:10913198] [PUBMED:11101851] [PUBMED:16201968] [PUBMED:12488457] [PUBMED:12370315] [PUBMED:19116245] [PUBMED:16025100] [PUBMED:11486044] [PUBMED:15607978] [PUBMED:15467735] [PUBMED:14739937] [PUBMED:9694793] [PUBMED:8749394] [PUBMED:16782059] [PUBMED:12972610] [PUBMED:17392792] [PUBMED:11334435] [PUBMED:11486045] [PUBMED:16753023] [PUBMED:15485867] [PUBMED:15866158] [PUBMED:16199874] [PUBMED:12374742] [PUBMED:9570950] [PUBMED:10964718] [PUBMED:16682003] [PUBMED:16287852] [PUBMED:10692439] [PUBMED:11095750] [PUBMED:11287612] [PUBMED:15314183] [PUBMED:15156153] [PUBMED:15684393] [PUBMED:7566092] [PUBMED:11604511] [PUBMED:9819403] [PUBMED:15563463] [PUBMED:15870295]
Peptide hormone metabolism [NCBI:1268746] [REACTOME:R-HSA-2980736] [PUBMED:2663045] [PUBMED:21805235]
Physiological factors [NCBI:1339122] [REACTOME:R-HSA-5578768] [PUBMED:25202235]
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) [NCBI:1268752] [REACTOME:R-HSA-400511] [PUBMED:19074620] [PUBMED:17498508] [PUBMED:17263764]
Thyroid hormone signaling pathway [NCBI:946598] [KEGG:hsa04919] [PUBMED:20005976] [PUBMED:17983645] [PUBMED:15345678] [PUBMED:16951130] [PUBMED:16214361] [PUBMED:18329679] [PUBMED:20051527] [PUBMED:17574003] [PUBMED:19716314] [PUBMED:19755667] [PUBMED:20868274] [PUBMED:21835053] [PUBMED:16051672] [PUBMED:19295177] [PUBMED:23021374] [PUBMED:22484490]
Tight junction [NCBI:83071] [KEGG:hsa04530] [PUBMED:25152334] [PUBMED:16650994] [PUBMED:22892070] [PUBMED:18946474] [PUBMED:12042308] [PUBMED:23885123] [PUBMED:16771626] [PUBMED:17182900] [PUBMED:21283798] [PUBMED:25757376] [PUBMED:22928510] [PUBMED:22169974] [PUBMED:25469537] [PUBMED:24651541] [PUBMED:15820555] [PUBMED:17525755] [PUBMED:27353478] [PUBMED:17950242] [PUBMED:18005931] [PUBMED:24548561] [PUBMED:21781017] [PUBMED:20094051] [PUBMED:20134025] [PUBMED:22896795] [PUBMED:18094055] [PUBMED:25483301]
YAP1- and WWTR1 (TAZ)-stimulated gene expression [NCBI:1269653] [REACTOME:R-HSA-2032785] [PUBMED:16332960] [PUBMED:20452772]
cGMP-PKG signaling pathway [NCBI:983748] [KEGG:hsa04022] [PUBMED:18006449] [PUBMED:9003029] [PUBMED:18040025] [PUBMED:19306895] [PUBMED:21666108] [PUBMED:12524221] [PUBMED:16460276] [PUBMED:20716671] [PUBMED:22785374] [PUBMED:11522789] [PUBMED:16439998] [PUBMED:16371594] [PUBMED:20388537] [PUBMED:18757523] [PUBMED:16815627] [PUBMED:23212367] [PUBMED:21685243] [PUBMED:20024580] [PUBMED:15894227] [PUBMED:22965426] [PUBMED:17643091] [PUBMED:19176601] [PUBMED:19961855]