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Genes
MCM4
Gene - MCM4
full name
minichromosome maintenance complex component 4
synonyms
CDC21, CDC54, hCdc21, NKCD, NKGCD, P1-CDC21, MCM4, ENSG00000104738
HGNC
HGNC:6947
Entrez Gene
Gene:4173
ENSEMBL
ENSG00000104738
location
chr: 8
start: 48872763
stop: 48890720
strand: +
OMIM
OMIM:602638
: MCM4
(Autosomal recessive inheritance)
OMIM:609981
: Immunodeficiency 54
transcripts
NM_005914.3
NM_182746.2
pathways
Activation of ATR in response to replication stress
[NCBI:1269757]
[REACTOME:R-HSA-176187]
[PUBMED:12791985]
Activation of the pre-replicative complex
[NCBI:1269773]
[REACTOME:R-HSA-68962]
[PUBMED:10402192]
[PUBMED:11779870]
[PUBMED:10801458]
[PUBMED:12169736]
[PUBMED:11323433]
[PUBMED:9038340]
[PUBMED:9765232]
[PUBMED:9829972]
[PUBMED:10970868]
[PUBMED:9353276]
[PUBMED:7502077]
[PUBMED:11459976]
[PUBMED:11395502]
Assembly of the pre-replicative complex
[NCBI:1269833]
[REACTOME:R-HSA-68867]
[PUBMED:11801723]
[PUBMED:9829972]
[PUBMED:9288745]
[PUBMED:9407030]
[PUBMED:9927482]
[PUBMED:9335335]
[PUBMED:11046155]
C-MYB transcription factor network
[NCBI:138073]
[Pathway Interaction Database:cmyb_pathway]
[PUBMED:17152050]
[PUBMED:1944282]
[PUBMED:7964503]
[PUBMED:8598284]
[PUBMED:15608679]
[PUBMED:10619021]
[PUBMED:2233716]
[PUBMED:9244354]
[PUBMED:8654374]
[PUBMED:10590070]
[PUBMED:17587615]
[PUBMED:12424255]
[PUBMED:1679531]
[PUBMED:17077080]
[PUBMED:8946914]
[PUBMED:16055116]
[PUBMED:11259163]
[PUBMED:9659917]
[PUBMED:9135152]
[PUBMED:7721782]
[PUBMED:11290610]
[PUBMED:12244173]
[PUBMED:11792321]
[PUBMED:17242210]
[PUBMED:10722757]
[PUBMED:8264615]
[PUBMED:15687240]
[PUBMED:14761981]
[PUBMED:10542314]
[PUBMED:12673198]
[PUBMED:11779867]
[PUBMED:8756344]
[PUBMED:11427482]
[PUBMED:9809063]
[PUBMED:10523863]
[PUBMED:11094072]
[PUBMED:15356292]
[PUBMED:11781241]
[PUBMED:15778089]
[PUBMED:9096387]
[PUBMED:17931383]
[PUBMED:14576818]
[PUBMED:11259170]
[PUBMED:8491193]
[PUBMED:11581319]
[PUBMED:10644988]
[PUBMED:7565722]
[PUBMED:9490676]
[PUBMED:9244356]
[PUBMED:17641686]
[PUBMED:16407849]
[PUBMED:1594249]
[PUBMED:17822556]
[PUBMED:15867358]
[PUBMED:17959653]
[PUBMED:7509358]
[PUBMED:11287612]
[PUBMED:15082531]
[PUBMED:10766162]
[PUBMED:8756629]
[PUBMED:11115410]
[PUBMED:7684005]
[PUBMED:9566892]
Cell Cycle
[NCBI:1269741]
[REACTOME:R-HSA-1640170]
Cell Cycle Checkpoints
[NCBI:1269742]
[REACTOME:R-HSA-69620]
Cell Cycle, Mitotic
[NCBI:1269763]
[REACTOME:R-HSA-69278]
Cell cycle
[NCBI:83054]
[KEGG:hsa04110]
[PUBMED:7973727]
[PUBMED:17568790]
[PUBMED:9832503]
[PUBMED:16936746]
[PUBMED:9029154]
[PUBMED:12573239]
[PUBMED:19020303]
[PUBMED:9618481]
[PUBMED:12809600]
[PUBMED:8242749]
[PUBMED:10385618]
[PUBMED:17426725]
[PUBMED:17018296]
[PUBMED:16212951]
[PUBMED:12925736]
[PUBMED:11099028]
[PUBMED:15568976]
[PUBMED:15838516]
[PUBMED:15838523]
[PUBMED:15876871]
[PUBMED:7908906]
[PUBMED:9889196]
DNA Replication
[NCBI:1269875]
[REACTOME:R-HSA-69306]
[PUBMED:11257218]
[PUBMED:12045100]
[PUBMED:1536007]
[PUBMED:10966477]
[PUBMED:1579437]
[PUBMED:8223461]
DNA Replication Pre-Initiation
[NCBI:1269832]
[REACTOME:R-HSA-69002]
DNA replication
[NCBI:83039]
[KEGG:hsa03030]
[PUBMED:9759502]
[PUBMED:8087839]
DNA strand elongation
[NCBI:1269784]
[REACTOME:R-HSA-69190]
[PUBMED:9081985]
[PUBMED:1976634]
[PUBMED:7623835]
[PUBMED:1536007]
[PUBMED:8594377]
G1/S Transition
[NCBI:1269768]
[REACTOME:R-HSA-69206]
G2/M Checkpoints
[NCBI:1269753]
[REACTOME:R-HSA-69481]
M/G1 Transition
[NCBI:1269831]
[REACTOME:R-HSA-68874]
Mitotic G1-G1/S phases
[NCBI:1269764]
[REACTOME:R-HSA-453279]
Orc1 removal from chromatin
[NCBI:1269782]
[REACTOME:R-HSA-68949]
[PUBMED:11931757]
[PUBMED:11739726]
[PUBMED:11809796]
[PUBMED:1110244]
Regulation of DNA replication
[NCBI:1269794]
[REACTOME:R-HSA-69304]
Removal of licensing factors from origins
[NCBI:1269796]
[REACTOME:R-HSA-69300]
S Phase
[NCBI:1269777]
[REACTOME:R-HSA-69242]
Switching of origins to a post-replicative state
[NCBI:1269781]
[REACTOME:R-HSA-69052]
Synthesis of DNA
[NCBI:1269779]
[REACTOME:R-HSA-69239]
Unwinding of DNA
[NCBI:1269785]
[REACTOME:R-HSA-176974]
[PUBMED:10834843]
[PUBMED:15707891]