full name
cytochrome P450 family 7 subfamily A member 1

synonyms
CP7A, CYP7, CYPVII, CYP7A1, ENSG00000167910

HGNC
HGNC:2651

Entrez Gene
Gene:1581

ENSEMBL
ENSG00000167910

location
chr: 8
start: 59402737
stop: 59412720
strand: -

transcripts
NM_000780.3

pathways
Bile acid and bile salt metabolism [NCBI:1270040] [REACTOME:R-HSA-194068] [PUBMED:12543708] [PUBMED:12663868] [PUBMED:14699511] [PUBMED:11969205]
Bile acid biosynthesis, cholesterol => cholate/chenodeoxycholate [NCBI:413432] [KEGG:hsa_M00104]
Bile secretion [NCBI:193146] [KEGG:hsa04976] [PUBMED:11826283] [PUBMED:19273385] [PUBMED:12663868] [PUBMED:15758646] [PUBMED:18837079] [PUBMED:15975683] [PUBMED:17404808] [PUBMED:18377365] [PUBMED:16706681] [PUBMED:10728790] [PUBMED:14659471] [PUBMED:18670431] [PUBMED:12483266] [PUBMED:19273238] [PUBMED:18668439] [PUBMED:18371245] [PUBMED:14999673] [PUBMED:11316487] [PUBMED:18081658] [PUBMED:19482594] [PUBMED:20103563]
Biological oxidations [NCBI:1270189] [REACTOME:R-HSA-211859]
Cytochrome P450 - arranged by substrate type [NCBI:1270191] [REACTOME:R-HSA-211897] [PUBMED:16584116] [PUBMED:15102545] [PUBMED:12369887]
Endogenous sterols [NCBI:1270192] [REACTOME:R-HSA-211976] [PUBMED:16872679] [PUBMED:15102545] [PUBMED:16584116]
Fatty acid, triacylglycerol, and ketone body metabolism [NCBI:1270010] [REACTOME:R-HSA-535734]
Metabolic pathways [NCBI:132956] [KEGG:hsa01100]
Metabolism [NCBI:1269956] [REACTOME:R-HSA-1430728]
Metabolism of lipids and lipoproteins [NCBI:1270001] [REACTOME:R-HSA-556833]
PPAR signaling pathway [NCBI:83042] [KEGG:hsa03320] [PUBMED:15673477] [PUBMED:15828221] [PUBMED:14999402] [PUBMED:15828222] [PUBMED:16601267] [PUBMED:15828220] [PUBMED:10529898] [PUBMED:15828223] [PUBMED:16476485] [PUBMED:11921433] [PUBMED:16511590] [PUBMED:16360030]
PPARA activates gene expression [NCBI:1270030] [REACTOME:R-HSA-1989781] [PUBMED:10529898] [PUBMED:18288277] [PUBMED:11330046] [PUBMED:20936127] [PUBMED:14999402]
Phase 1 - Functionalization of compounds [NCBI:1270190] [REACTOME:R-HSA-211945] [PUBMED:12369887] [PUBMED:17125408] [PUBMED:16584116]
Primary bile acid biosynthesis [NCBI:82938] [KEGG:hsa00120] [PUBMED:16299351] [PUBMED:11067870] [PUBMED:9292932] [PUBMED:10198776] [PUBMED:18488143] [PUBMED:12543708] [PUBMED:18081658] [PUBMED:17346171]
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) [NCBI:1270029] [REACTOME:R-HSA-400206] [PUBMED:18288277] [PUBMED:10529898] [PUBMED:16476485] [PUBMED:16503871]
Steroid hormone biosynthesis [NCBI:82940] [KEGG:hsa00140] [PUBMED:15642792] [PUBMED:16413106] [PUBMED:12832414] [PUBMED:17475203] [PUBMED:12604236] [PUBMED:10998348] [PUBMED:11469811] [PUBMED:16547389] [PUBMED:17926129] [PUBMED:17459698]
Synthesis of bile acids and bile salts [NCBI:1270041] [REACTOME:R-HSA-192105] [PUBMED:12543708] [PUBMED:11969205]
Synthesis of bile acids and bile salts via 27-hydroxycholesterol [NCBI:1270044] [REACTOME:R-HSA-193807] [PUBMED:10428977] [PUBMED:12543708] [PUBMED:11969205] [PUBMED:8078928]
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol [NCBI:1270042] [REACTOME:R-HSA-193368] [PUBMED:12543708]
bile acid biosynthesis, neutral pathway [NCBI:545316] [BIOCYC:HUMAN_PWY-6061] [PUBMED:18538142] [PUBMED:17346171] [PUBMED:15769750] [PUBMED:11146090] [PUBMED:12543708] [PUBMED:9390170] [PUBMED:3746130] [PUBMED:11673457] [PUBMED:18815433] [PUBMED:6736016] [PUBMED:3459552] [PUBMED:9307041] [PUBMED:11969205] [PUBMED:9538213] [PUBMED:9215542] [PUBMED:624713] [PUBMED:2848026]