full name
cytochrome P450 family 7 subfamily B member 1

synonyms
CBAS3, CP7B, SPG5A, CYP7B1, ENSG00000172817

HGNC
HGNC:2652

Entrez Gene
Gene:9420

ENSEMBL
ENSG00000172817

location
chr: 8
start: 65508529
stop: 65711348
strand: -

OMIM
OMIM:603711: CYP7B1 (Autosomal recessive inheritance)
OMIM:613812: Bile acid synthesis defect, congenital, 3
OMIM:270800: Spastic paraplegia 5A, autosomal recessive

transcripts
NM_004820.3

pathways
Bile acid and bile salt metabolism [NCBI:1270040] [REACTOME:R-HSA-194068] [PUBMED:12543708] [PUBMED:12663868] [PUBMED:14699511] [PUBMED:11969205]
Biological oxidations [NCBI:1270189] [REACTOME:R-HSA-211859]
Cytochrome P450 - arranged by substrate type [NCBI:1270191] [REACTOME:R-HSA-211897] [PUBMED:16584116] [PUBMED:15102545] [PUBMED:12369887]
Endogenous sterols [NCBI:1270192] [REACTOME:R-HSA-211976] [PUBMED:16872679] [PUBMED:15102545] [PUBMED:16584116]
Metabolism [NCBI:1269956] [REACTOME:R-HSA-1430728]
Metabolism of lipids and lipoproteins [NCBI:1270001] [REACTOME:R-HSA-556833]
Phase 1 - Functionalization of compounds [NCBI:1270190] [REACTOME:R-HSA-211945] [PUBMED:12369887] [PUBMED:17125408] [PUBMED:16584116]
Primary bile acid biosynthesis [NCBI:82938] [KEGG:hsa00120] [PUBMED:16299351] [PUBMED:11067870] [PUBMED:9292932] [PUBMED:10198776] [PUBMED:18488143] [PUBMED:12543708] [PUBMED:18081658] [PUBMED:17346171]
Steroid hormone biosynthesis [NCBI:82940] [KEGG:hsa00140] [PUBMED:15642792] [PUBMED:16413106] [PUBMED:12832414] [PUBMED:17475203] [PUBMED:12604236] [PUBMED:10998348] [PUBMED:11469811] [PUBMED:16547389] [PUBMED:17926129] [PUBMED:17459698]
Synthesis of bile acids and bile salts [NCBI:1270041] [REACTOME:R-HSA-192105] [PUBMED:12543708] [PUBMED:11969205]
Synthesis of bile acids and bile salts via 27-hydroxycholesterol [NCBI:1270044] [REACTOME:R-HSA-193807] [PUBMED:10428977] [PUBMED:12543708] [PUBMED:11969205] [PUBMED:8078928]
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol [NCBI:1270042] [REACTOME:R-HSA-193368] [PUBMED:12543708]