Logo
full name
adenosylhomocysteinase like 1

synonyms
DCAL, IRBIT, PRO0233, XPVKONA, AHCYL1, ENSG00000168710

HGNC
HGNC:344

Entrez Gene
Gene:10768

ENSEMBL
ENSG00000168710

location
chr: 1
start: 110527387
stop: 110566364
strand: +

transcripts
NM_001242673.1
NM_006621.5
NM_001242674.1
NM_001242675.1
NM_001242676.1

pathways
Adaptive Immune System [NCBI:1269171] [REACTOME:R-HSA-1280218] [PUBMED:16551257] [PUBMED:21682741] [PUBMED:11861602]
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers [NCBI:1269184] [REACTOME:R-HSA-983695] [PUBMED:8163536] [PUBMED:18818202] [PUBMED:15489917] [PUBMED:20206686] [PUBMED:7592958] [PUBMED:6335036] [PUBMED:8918697] [PUBMED:7688784] [PUBMED:1376928] [PUBMED:1550550] [PUBMED:15509800] [PUBMED:7524079] [PUBMED:7927516] [PUBMED:9341187] [PUBMED:18187424] [PUBMED:803528] [PUBMED:20192804] [PUBMED:7929028] [PUBMED:10770799] [PUBMED:16849466] [PUBMED:8306975] [PUBMED:11606584] [PUBMED:1702903] [PUBMED:2011584] [PUBMED:7538118] [PUBMED:19065780] [PUBMED:1375264] [PUBMED:1081164] [PUBMED:15161916] [PUBMED:11901194] [PUBMED:18596693] [PUBMED:8580068] [PUBMED:19249086] [PUBMED:9468499] [PUBMED:11226282] [PUBMED:12456653] [PUBMED:10648173] [PUBMED:9697839] [PUBMED:4589993]
C-type lectin receptors (CLRs) [NCBI:1269303] [REACTOME:R-HSA-5621481] [PUBMED:19521399] [PUBMED:24330199]
CLEC7A (Dectin-1) induces NFAT activation [NCBI:1269305] [REACTOME:R-HSA-5607763] [PUBMED:17312158] [PUBMED:22611159] [PUBMED:21728173]
CLEC7A (Dectin-1) signaling [NCBI:1269304] [REACTOME:R-HSA-5607764] [PUBMED:12719478] [PUBMED:19223162]
Cardiac conduction [NCBI:1339115] [REACTOME:R-HSA-5576891] [PUBMED:19808464] [PUBMED:26140724] [PUBMED:21357845]
Cysteine and methionine metabolism [NCBI:104488] [KEGG:hsa00270] [PUBMED:18391471] [PUBMED:14551435] [PUBMED:15102328] [PUBMED:12644499] [PUBMED:12670965] [PUBMED:18625006] [PUBMED:19270684] [PUBMED:17169919] [PUBMED:17030798] [PUBMED:10613873] [PUBMED:18520135] [PUBMED:12022921]
DAG and IP3 signaling [NCBI:1269291] [REACTOME:R-HSA-1489509] [PUBMED:16260143]
DAP12 interactions [NCBI:1269283] [REACTOME:R-HSA-2172127] [PUBMED:19120482] [PUBMED:17220916] [PUBMED:9490415] [PUBMED:18192027] [PUBMED:15884055]
DAP12 signaling [NCBI:1269284] [REACTOME:R-HSA-2424491] [PUBMED:15884055] [PUBMED:17110943] [PUBMED:17220916]
Downstream signal transduction [NCBI:1269479] [REACTOME:R-HSA-186763] [PUBMED:10508235] [PUBMED:9739761]
EGFR interacts with phospholipase C-gamma [NCBI:1269381] [REACTOME:R-HSA-212718] [PUBMED:1501243]
FCERI mediated Ca+2 mobilization [NCBI:1269300] [REACTOME:R-HSA-2871809] [PUBMED:17336609] [PUBMED:10807788] [PUBMED:1309940]
Fc epsilon receptor (FCERI) signaling [NCBI:1269298] [REACTOME:R-HSA-2454202] [PUBMED:15099567] [PUBMED:21799019]
Fcgamma receptor (FCGR) dependent phagocytosis [NCBI:1269279] [REACTOME:R-HSA-2029480] [PUBMED:8541526] [PUBMED:12488490] [PUBMED:16413920] [PUBMED:17050193]
G-protein mediated events [NCBI:1269586] [REACTOME:R-HSA-112040] [PUBMED:9422713] [PUBMED:9218123]
Immune System [NCBI:1269170] [REACTOME:R-HSA-168256]
Innate Immune System [NCBI:1269203] [REACTOME:R-HSA-168249]
Integration of energy metabolism [NCBI:1270101] [REACTOME:R-HSA-163685] [PUBMED:15509864] [PUBMED:12721358] [PUBMED:12626323]
Ion homeostasis [NCBI:1339121] [REACTOME:R-HSA-5578775] [PUBMED:26140724] [PUBMED:17017901]
Metabolic pathways [NCBI:132956] [KEGG:hsa01100]
Metabolism [NCBI:1269956] [REACTOME:R-HSA-1430728]
Methionine degradation [NCBI:413353] [KEGG:hsa_M00035]
Muscle contraction [NCBI:1269868] [REACTOME:R-HSA-397014]
NGF signalling via TRKA from the plasma membrane [NCBI:1269460] [REACTOME:R-HSA-187037] [PUBMED:11520933] [PUBMED:12676795] [PUBMED:10851172] [PUBMED:10579918]
Opioid Signalling [NCBI:1269584] [REACTOME:R-HSA-111885] [PUBMED:9422713] [PUBMED:9218123] [PUBMED:16612131]
PLC beta mediated events [NCBI:1269587] [REACTOME:R-HSA-112043] [PUBMED:9218123] [PUBMED:16183910] [PUBMED:1335363]
PLC-gamma1 signalling [NCBI:1269472] [REACTOME:R-HSA-167021] [PUBMED:12676795] [PUBMED:10579907]
Regulation of insulin secretion [NCBI:1270102] [REACTOME:R-HSA-422356] [PUBMED:18200017] [PUBMED:11078440] [PUBMED:16321791] [PUBMED:11815463] [PUBMED:16556766]
Role of phospholipids in phagocytosis [NCBI:1269282] [REACTOME:R-HSA-2029485] [PUBMED:10224668] [PUBMED:20400677]
Signal Transduction [NCBI:1269379] [REACTOME:R-HSA-162582] [PUBMED:17604717] [PUBMED:19648010] [PUBMED:16260143] [PUBMED:11742412] [PUBMED:19536106] [PUBMED:15863030] [PUBMED:19379690] [PUBMED:19458711] [PUBMED:19935667] [PUBMED:21252999] [PUBMED:15520807] [PUBMED:17496910] [PUBMED:15450248] [PUBMED:18043707] [PUBMED:16939974] [PUBMED:19762341] [PUBMED:18483217] [PUBMED:17084981] [PUBMED:21781017] [PUBMED:19619488]
Signaling by EGFR [NCBI:1269380] [REACTOME:R-HSA-177929] [PUBMED:10459005] [PUBMED:10404636] [PUBMED:12297041] [PUBMED:15142631]
Signaling by GPCR [NCBI:1269543] [REACTOME:R-HSA-372790] [PUBMED:16902930] [PUBMED:10202136] [PUBMED:18043707]
Signaling by PDGF [NCBI:1269478] [REACTOME:R-HSA-186797] [PUBMED:15207811] [PUBMED:10508235] [PUBMED:9739761]
Signaling by VEGF [NCBI:1269480] [REACTOME:R-HSA-194138] [PUBMED:15585754] [PUBMED:13678960] [PUBMED:16336962] [PUBMED:16835467]
Signaling by the B Cell Receptor (BCR) [NCBI:1269183] [REACTOME:R-HSA-983705] [PUBMED:1702903] [PUBMED:2011584] [PUBMED:1081164] [PUBMED:19065780] [PUBMED:16849466] [PUBMED:1375264] [PUBMED:7538118] [PUBMED:11901194] [PUBMED:8580068] [PUBMED:19249086] [PUBMED:18596693] [PUBMED:10648173] [PUBMED:4589993] [PUBMED:8163536] [PUBMED:1376928] [PUBMED:7688784] [PUBMED:6335036] [PUBMED:17052215] [PUBMED:18818202] [PUBMED:20206686] [PUBMED:7592958] [PUBMED:7524079] [PUBMED:15489917] [PUBMED:15509800] [PUBMED:18187424] [PUBMED:7927516] [PUBMED:803528] [PUBMED:19909372] [PUBMED:20192804] [PUBMED:8306975]
Signalling by NGF [NCBI:1269443] [REACTOME:R-HSA-166520]
VEGFA-VEGFR2 Pathway [NCBI:1269483] [REACTOME:R-HSA-4420097] [PUBMED:17344076] [PUBMED:16633338] [PUBMED:19230644] [PUBMED:13678960]
VEGFR2 mediated cell proliferation [NCBI:1269485] [REACTOME:R-HSA-5218921] [PUBMED:22866201] [PUBMED:22180219] [PUBMED:22762016]