full name
WW domain containing E3 ubiquitin protein ligase 1

synonyms
AIP5, hSDRP1, Tiul1, WWP1, ENSG00000123124

HGNC
HGNC:17004

Entrez Gene
Gene:11059

ENSEMBL
ENSG00000123124

location
chr: 8
start: 87354965
stop: 87480181
strand: +

transcripts
NM_007013.3

pathways
Adaptive Immune System [NCBI:1269171] [REACTOME:R-HSA-1280218] [PUBMED:16551257] [PUBMED:21682741] [PUBMED:11861602]
Antigen processing: Ubiquitination & Proteasome degradation [NCBI:1269193] [REACTOME:R-HSA-983168] [PUBMED:12648452] [PUBMED:11917093] [PUBMED:19489725] [PUBMED:14734113] [PUBMED:20351195] [PUBMED:17145306]
Class I MHC mediated antigen processing & presentation [NCBI:1269192] [REACTOME:R-HSA-983169] [PUBMED:8717519] [PUBMED:17145306] [PUBMED:18926908] [PUBMED:17055423] [PUBMED:12495737] [PUBMED:18641646] [PUBMED:18243674]
Downregulation of ERBB4 signaling [NCBI:1269500] [REACTOME:R-HSA-1253288]
Endocytosis [NCBI:102279] [KEGG:hsa04144] [PUBMED:19696797] [PUBMED:19007773] [PUBMED:16203612] [PUBMED:15687999] [PUBMED:19924646] [PUBMED:15261671] [PUBMED:18647649] [PUBMED:19325624] [PUBMED:20110990] [PUBMED:22193161]
ErbB4 signaling events [NCBI:137991] [Pathway Interaction Database:erbb4_pathway] [PUBMED:16815842] [PUBMED:8617750] [PUBMED:9663464] [PUBMED:12466964] [PUBMED:15345710] [PUBMED:16061658] [PUBMED:12954715] [PUBMED:17463226] [PUBMED:17646177] [PUBMED:17085783] [PUBMED:18721752] [PUBMED:15023535] [PUBMED:9556621] [PUBMED:12807903] [PUBMED:17486069] [PUBMED:10358079] [PUBMED:12454007] [PUBMED:8702723] [PUBMED:10693928] [PUBMED:18334649] [PUBMED:10725395] [PUBMED:11731109] [PUBMED:7477376] [PUBMED:16837552] [PUBMED:15863494] [PUBMED:19047365] [PUBMED:10722704] [PUBMED:19193720] [PUBMED:10348342] [PUBMED:17018285] [PUBMED:9135143] [PUBMED:9618494] [PUBMED:12716924] [PUBMED:18819924] [PUBMED:10867024] [PUBMED:15985438] [PUBMED:7559778] [PUBMED:7759543] [PUBMED:12824469] [PUBMED:10744726] [PUBMED:15746097] [PUBMED:18653779] [PUBMED:15534001] [PUBMED:17460065] [PUBMED:10508857] [PUBMED:15282549] [PUBMED:9362517] [PUBMED:9685416] [PUBMED:11679632] [PUBMED:10839362] [PUBMED:10353604]
Immune System [NCBI:1269170] [REACTOME:R-HSA-168256]
Ion channel transport [NCBI:1269950] [REACTOME:R-HSA-983712] [PUBMED:15071553]
Signal Transduction [NCBI:1269379] [REACTOME:R-HSA-162582] [PUBMED:17604717] [PUBMED:19648010] [PUBMED:16260143] [PUBMED:11742412] [PUBMED:19536106] [PUBMED:15863030] [PUBMED:19379690] [PUBMED:19458711] [PUBMED:19935667] [PUBMED:21252999] [PUBMED:15520807] [PUBMED:17496910] [PUBMED:15450248] [PUBMED:18043707] [PUBMED:16939974] [PUBMED:19762341] [PUBMED:18483217] [PUBMED:17084981] [PUBMED:21781017] [PUBMED:19619488]
Signaling by ERBB4 [NCBI:1269496] [REACTOME:R-HSA-1236394] [PUBMED:9275162] [PUBMED:9168115] [PUBMED:17545517] [PUBMED:19193720] [PUBMED:16914727] [PUBMED:7929212] [PUBMED:16912174] [PUBMED:9135143] [PUBMED:10867024] [PUBMED:16778220] [PUBMED:17018285] [PUBMED:15534001] [PUBMED:8665853] [PUBMED:1706616] [PUBMED:10744726] [PUBMED:18653779] [PUBMED:11679632] [PUBMED:8617750] [PUBMED:7565730] [PUBMED:15023535] [PUBMED:16061658] [PUBMED:18721752] [PUBMED:16978839] [PUBMED:17463226] [PUBMED:10722704] [PUBMED:12869563] [PUBMED:19047365] [PUBMED:12807903] [PUBMED:9556621]
Stimuli-sensing channels [NCBI:1269953] [REACTOME:R-HSA-2672351] [PUBMED:15728426] [PUBMED:16460286] [PUBMED:12907679] [PUBMED:18391176] [PUBMED:19278523] [PUBMED:11904445] [PUBMED:22934072] [PUBMED:20807551] [PUBMED:19783045] [PUBMED:16219661] [PUBMED:21932071] [PUBMED:22277752]
TGF-beta receptor signaling [NCBI:138024] [Pathway Interaction Database:tgfbrpathway] [PUBMED:12118366] [PUBMED:8242743] [PUBMED:15221015] [PUBMED:9335507] [PUBMED:11278302] [PUBMED:16601693] [PUBMED:8391934] [PUBMED:1333888] [PUBMED:11438668] [PUBMED:17327236] [PUBMED:2879635] [PUBMED:11483955] [PUBMED:12717440] [PUBMED:8047140] [PUBMED:8576253] [PUBMED:9865696] [PUBMED:9346908] [PUBMED:17197390] [PUBMED:8533096] [PUBMED:8756725] [PUBMED:10615055] [PUBMED:10934479] [PUBMED:16251192] [PUBMED:7706248] [PUBMED:15946939] [PUBMED:7774578] [PUBMED:7988555] [PUBMED:11278251] [PUBMED:11027280] [PUBMED:17420258] [PUBMED:9169454] [PUBMED:12151385] [PUBMED:10757800] [PUBMED:12543979] [PUBMED:12475967] [PUBMED:9679059] [PUBMED:17673906] [PUBMED:9774674] [PUBMED:8893010] [PUBMED:1544886] [PUBMED:12958365] [PUBMED:12110587] [PUBMED:9233797] [PUBMED:11163210] [PUBMED:15496141] [PUBMED:7693660] [PUBMED:14657019] [PUBMED:12429842] [PUBMED:11124802] [PUBMED:11389444] [PUBMED:8798398] [PUBMED:15356634] [PUBMED:17272273] [PUBMED:1657407] [PUBMED:12589052] [PUBMED:11016919] [PUBMED:14718519] [PUBMED:10777621] [PUBMED:17384642] [PUBMED:1310899] [PUBMED:9856985] [PUBMED:10519551] [PUBMED:9155023] [PUBMED:12134160] [PUBMED:9215638] [PUBMED:12134149] [PUBMED:16157589] [PUBMED:12356868] [PUBMED:11387212] [PUBMED:12034739] [PUBMED:11739411] [PUBMED:15761148] [PUBMED:9463378] [PUBMED:11583628] [PUBMED:15684397] [PUBMED:8947046] [PUBMED:11781097]
Transmembrane transport of small molecules [NCBI:1269903] [REACTOME:R-HSA-382551]
Ubiquitin mediated proteolysis [NCBI:83056] [KEGG:hsa04120] [PUBMED:16405856] [PUBMED:12944364] [PUBMED:16922408] [PUBMED:17588513] [PUBMED:16922367] [PUBMED:16922370] [PUBMED:16816840]