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Genes
SH3GL2
Gene - SH3GL2
full name
SH3 domain containing GRB2 like 2, endophilin A1
synonyms
CNSA2, EEN-B1, SH3D2A, SH3P4, SH3GL2, ENSG00000107295
HGNC
HGNC:10831
Entrez Gene
Gene:6456
ENSEMBL
ENSG00000107295
location
chr: 9
start: 17578953
stop: 17797122
strand: +
transcripts
NM_003026.2
pathways
Adaptive Immune System
[NCBI:1269171]
[REACTOME:R-HSA-1280218]
[PUBMED:16551257]
[PUBMED:21682741]
[PUBMED:11861602]
Axon guidance
[NCBI:83065]
[KEGG:hsa04360]
[NCBI:1270303]
[REACTOME:R-HSA-422475]
[PUBMED:14682358]
[PUBMED:15084255]
[PUBMED:11687826]
[PUBMED:15818466]
[PUBMED:15363605]
[PUBMED:12471249]
[PUBMED:15630019]
[PUBMED:11891122]
[PUBMED:15960985]
[PUBMED:12677003]
Cargo recognition for clathrin-mediated endocytosis
[NCBI:1427859]
[REACTOME:R-HSA-8856825]
[PUBMED:24186068]
[PUBMED:12952941]
[PUBMED:19696796]
[PUBMED:14985334]
[PUBMED:20448150]
[PUBMED:20485680]
[PUBMED:16382132]
[PUBMED:23482940]
[PUBMED:16870701]
Clathrin derived vesicle budding
[NCBI:1269881]
[REACTOME:R-HSA-421837]
Clathrin-mediated endocytosis
[NCBI:1427858]
[REACTOME:R-HSA-8856828]
[PUBMED:16516836]
[PUBMED:15339664]
[PUBMED:19754444]
[PUBMED:8552632]
[PUBMED:21779028]
[PUBMED:12353027]
[PUBMED:23891661]
[PUBMED:21613550]
[PUBMED:20059951]
[PUBMED:21447041]
[PUBMED:17620409]
[PUBMED:16903783]
[PUBMED:21445324]
[PUBMED:19696798]
[PUBMED:26246598]
[PUBMED:25085911]
[PUBMED:24186068]
[PUBMED:26829388]
[PUBMED:27092250]
[PUBMED:24581490]
[PUBMED:26042225]
[PUBMED:23823722]
[PUBMED:24789820]
[PUBMED:9736607]
[PUBMED:23637288]
[PUBMED:22233676]
[PUBMED:19458185]
[PUBMED:26403691]
[PUBMED:19296720]
[PUBMED:15703209]
[PUBMED:20428113]
[PUBMED:8953040]
[PUBMED:1177317]
[PUBMED:9092476]
[PUBMED:26872272]
[PUBMED:19092055]
Developmental Biology
[NCBI:1270302]
[REACTOME:R-HSA-1266738]
Disease
[NCBI:1268854]
[REACTOME:R-HSA-1643685]
EGFR downregulation
[NCBI:1269385]
[REACTOME:R-HSA-182971]
[PUBMED:11283727]
[PUBMED:15021893]
[PUBMED:14641021]
Endocytosis
[NCBI:102279]
[KEGG:hsa04144]
[PUBMED:19696797]
[PUBMED:19007773]
[PUBMED:16203612]
[PUBMED:15687999]
[PUBMED:19924646]
[PUBMED:15261671]
[PUBMED:18647649]
[PUBMED:19325624]
[PUBMED:20110990]
[PUBMED:22193161]
Golgi Associated Vesicle Biogenesis
[NCBI:1269882]
[REACTOME:R-HSA-432722]
Immune System
[NCBI:1269170]
[REACTOME:R-HSA-168256]
Infectious disease
[NCBI:1269056]
[REACTOME:R-HSA-5663205]
InlB-mediated entry of Listeria monocytogenes into host cell
[NCBI:1470919]
[REACTOME:R-HSA-8875360]
[PUBMED:20670691]
[PUBMED:11081636]
[PUBMED:19900460]
[PUBMED:19432801]
[PUBMED:17662939]
[PUBMED:16113677]
Internalization of ErbB1
[NCBI:138013]
[Pathway Interaction Database:erbb1_internalization_pathway]
[PUBMED:9733512]
[PUBMED:9950686]
[PUBMED:12839496]
[PUBMED:10953014]
[PUBMED:17052190]
[PUBMED:15212941]
[PUBMED:19460345]
[PUBMED:18316398]
[PUBMED:11823423]
[PUBMED:18657070]
[PUBMED:12242303]
[PUBMED:17940017]
[PUBMED:15465819]
[PUBMED:17121848]
[PUBMED:15772153]
[PUBMED:18508924]
[PUBMED:18031739]
[PUBMED:16914641]
[PUBMED:11408594]
[PUBMED:11099046]
[PUBMED:16543144]
[PUBMED:11703925]
[PUBMED:11894095]
[PUBMED:15282549]
[PUBMED:9851973]
[PUBMED:16554368]
[PUBMED:12897150]
[PUBMED:11983899]
[PUBMED:18362181]
[PUBMED:15475003]
[PUBMED:12631709]
[PUBMED:15701692]
[PUBMED:16862145]
[PUBMED:16735510]
[PUBMED:18694561]
[PUBMED:14505571]
[PUBMED:10567412]
[PUBMED:15635092]
[PUBMED:15210722]
[PUBMED:16892055]
[PUBMED:1645724]
[PUBMED:16407834]
[PUBMED:17363458]
[PUBMED:16382132]
[PUBMED:10428778]
[PUBMED:15314065]
[PUBMED:16120644]
[PUBMED:7925272]
[PUBMED:12234920]
[PUBMED:8175702]
[PUBMED:10085141]
[PUBMED:11375397]
[PUBMED:10635327]
[PUBMED:19723633]
[PUBMED:10788520]
[PUBMED:12218189]
[PUBMED:19054389]
L1CAM interactions
[NCBI:1270323]
[REACTOME:R-HSA-373760]
[PUBMED:9211984]
[PUBMED:18760361]
[PUBMED:14709786]
[PUBMED:17189949]
[PUBMED:19356150]
Listeria monocytogenes entry into host cells
[NCBI:1470917]
[REACTOME:R-HSA-8876384]
[PUBMED:23125201]
[PUBMED:21921683]
[PUBMED:23376167]
[PUBMED:25624443]
[PUBMED:19191787]
[PUBMED:20485518]
[PUBMED:15337781]
Lysosome Vesicle Biogenesis
[NCBI:1269883]
[REACTOME:R-HSA-432720]
MHC class II antigen presentation
[NCBI:1269200]
[REACTOME:R-HSA-2132295]
[PUBMED:19703008]
[PUBMED:9316394]
[PUBMED:11684289]
[PUBMED:19217269]
[PUBMED:8689559]
Membrane Trafficking
[NCBI:1269877]
[REACTOME:R-HSA-199991]
[PUBMED:11031247]
NGF signalling via TRKA from the plasma membrane
[NCBI:1269460]
[REACTOME:R-HSA-187037]
[PUBMED:11520933]
[PUBMED:12676795]
[PUBMED:10851172]
[PUBMED:10579918]
Negative regulation of MET activity
[NCBI:1457805]
[REACTOME:R-HSA-6807004]
[PUBMED:24828152]
[PUBMED:11894096]
[PUBMED:14684163]
[PUBMED:12475979]
[PUBMED:23208509]
[PUBMED:9001234]
[PUBMED:11420688]
[PUBMED:18819921]
[PUBMED:11741535]
[PUBMED:15314156]
Recycling pathway of L1
[NCBI:1270324]
[REACTOME:R-HSA-437239]
[PUBMED:10804209]
[PUBMED:11717353]
[PUBMED:14709786]
Retrograde neurotrophin signalling
[NCBI:1269476]
[REACTOME:R-HSA-177504]
RhoA signaling pathway
[NCBI:169356]
[Pathway Interaction Database:rhoa_pathway]
[PUBMED:8641286]
[PUBMED:16705166]
[PUBMED:9510209]
[PUBMED:18267089]
[PUBMED:15866170]
[PUBMED:18303050]
[PUBMED:17588931]
[PUBMED:18941185]
[PUBMED:16164598]
[PUBMED:11238375]
[PUBMED:18559669]
[PUBMED:18025109]
[PUBMED:16427251]
[PUBMED:11122380]
[PUBMED:8632828]
[PUBMED:15866889]
[PUBMED:9707430]
[PUBMED:9456324]
[PUBMED:8662509]
[PUBMED:12429848]
[PUBMED:9294169]
[PUBMED:9042860]
[PUBMED:9582304]
[PUBMED:15170389]
[PUBMED:10744700]
[PUBMED:10893221]
[PUBMED:14681219]
[PUBMED:9121475]
[PUBMED:8858161]
[PUBMED:18309323]
[PUBMED:9710582]
[PUBMED:9265657]
[PUBMED:19625450]
[PUBMED:15068801]
[PUBMED:11278519]
[PUBMED:12732141]
[PUBMED:9529607]
[PUBMED:12600823]
[PUBMED:9697773]
[PUBMED:10085083]
[PUBMED:12802051]
[PUBMED:11018042]
[PUBMED:7600583]
[PUBMED:9693382]
[PUBMED:12899698]
[PUBMED:8702756]
[PUBMED:10556088]
[PUBMED:10037681]
[PUBMED:1643657]
[PUBMED:12034774]
[PUBMED:9670022]
[PUBMED:12574166]
[PUBMED:12584113]
[PUBMED:11877391]
[PUBMED:9920882]
[PUBMED:8995216]
[PUBMED:7929302]
[PUBMED:10428028]
[PUBMED:15793569]
[PUBMED:14595335]
[PUBMED:10436006]
[PUBMED:9482732]
[PUBMED:11342553]
[PUBMED:9351440]
Signal Transduction
[NCBI:1269379]
[REACTOME:R-HSA-162582]
[PUBMED:17604717]
[PUBMED:19648010]
[PUBMED:16260143]
[PUBMED:11742412]
[PUBMED:19536106]
[PUBMED:15863030]
[PUBMED:19379690]
[PUBMED:19458711]
[PUBMED:19935667]
[PUBMED:21252999]
[PUBMED:15520807]
[PUBMED:17496910]
[PUBMED:15450248]
[PUBMED:18043707]
[PUBMED:16939974]
[PUBMED:19762341]
[PUBMED:18483217]
[PUBMED:17084981]
[PUBMED:21781017]
[PUBMED:19619488]
Signaling by EGFR
[NCBI:1269380]
[REACTOME:R-HSA-177929]
[PUBMED:10459005]
[PUBMED:10404636]
[PUBMED:12297041]
[PUBMED:15142631]
Signaling by MET
[NCBI:1457794]
[REACTOME:R-HSA-6806834]
[PUBMED:1846706]
[PUBMED:12948444]
[PUBMED:16782899]
[PUBMED:15249655]
[PUBMED:22270953]
[PUBMED:15167892]
[PUBMED:7708691]
[PUBMED:11081636]
[PUBMED:8384622]
[PUBMED:21102609]
[PUBMED:16461907]
[PUBMED:9407027]
[PUBMED:7854453]
[PUBMED:7651534]
[PUBMED:9070211]
[PUBMED:8208547]
[PUBMED:24518591]
[PUBMED:6590967]
[PUBMED:15180923]
[PUBMED:20802513]
[PUBMED:10521801]
[PUBMED:9038378]
[PUBMED:17403932]
[PUBMED:1655790]
[PUBMED:12006644]
[PUBMED:7513258]
[PUBMED:18614017]
[PUBMED:10753869]
[PUBMED:17662939]
[PUBMED:14685170]
[PUBMED:10734310]
[PUBMED:1827664]
[PUBMED:7731718]
[PUBMED:19996456]
[PUBMED:11430831]
[PUBMED:8302603]
[PUBMED:15218027]
[PUBMED:9140397]
[PUBMED:2423252]
[PUBMED:16113677]
[PUBMED:12147692]
[PUBMED:10648629]
[PUBMED:7854452]
[PUBMED:15070743]
[PUBMED:15301554]
[PUBMED:19881549]
[PUBMED:25992381]
[PUBMED:10871282]
[PUBMED:12726861]
Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
[NCBI:137930]
[Pathway Interaction Database:met_pathway]
[PUBMED:10793146]
[PUBMED:8906793]
[PUBMED:11929826]
[PUBMED:10022866]
[PUBMED:11532961]
[PUBMED:12475979]
[PUBMED:1718989]
[PUBMED:1846706]
[PUBMED:10970810]
[PUBMED:10516287]
[PUBMED:12138161]
[PUBMED:11046147]
[PUBMED:18073207]
[PUBMED:12951049]
[PUBMED:15494312]
[PUBMED:9001234]
[PUBMED:11352916]
[PUBMED:11896055]
[PUBMED:9440692]
[PUBMED:8607979]
[PUBMED:12244132]
[PUBMED:11162460]
[PUBMED:11809798]
[PUBMED:9693375]
[PUBMED:14636584]
[PUBMED:17297451]
[PUBMED:17682062]
[PUBMED:19628037]
[PUBMED:11069926]
[PUBMED:18819921]
[PUBMED:16423831]
[PUBMED:10558875]
[PUBMED:16858414]
[PUBMED:10995442]
[PUBMED:20332103]
[PUBMED:11146548]
[PUBMED:18346875]
[PUBMED:17894413]
[PUBMED:9252406]
[PUBMED:17635922]
[PUBMED:11134526]
[PUBMED:2005882]
[PUBMED:19609305]
[PUBMED:8380735]
[PUBMED:16537482]
[PUBMED:10618718]
[PUBMED:9591773]
[PUBMED:12894582]
[PUBMED:9748249]
[PUBMED:11741535]
[PUBMED:17881575]
[PUBMED:10713050]
[PUBMED:1655790]
[PUBMED:11784715]
[PUBMED:10753869]
[PUBMED:10713700]
[PUBMED:11118451]
[PUBMED:16952352]
[PUBMED:15314156]
[PUBMED:19272169]
[PUBMED:12802068]
[PUBMED:17363898]
[PUBMED:7513258]
[PUBMED:1827664]
[PUBMED:2541345]
[PUBMED:8387483]
[PUBMED:16620780]
[PUBMED:11445578]
[PUBMED:10734310]
[PUBMED:16227611]
[PUBMED:12941962]
[PUBMED:15735664]
[PUBMED:19071214]
[PUBMED:7731718]
[PUBMED:19289496]
[PUBMED:11438654]
[PUBMED:11896612]
[PUBMED:11894096]
[PUBMED:11896575]
[PUBMED:7499247]
[PUBMED:12147692]
[PUBMED:11948414]
[PUBMED:19881549]
[PUBMED:19525225]
[PUBMED:14684163]
[PUBMED:17055484]
[PUBMED:9668053]
[PUBMED:10531383]
[PUBMED:9681449]
[PUBMED:1655405]
[PUBMED:12686592]
[PUBMED:19109251]
[PUBMED:10679787]
[PUBMED:9487126]
[PUBMED:9886295]
[PUBMED:12058075]
[PUBMED:15452053]
[PUBMED:9184210]
[PUBMED:10871282]
[PUBMED:17329361]
[PUBMED:2554238]
Signalling by NGF
[NCBI:1269443]
[REACTOME:R-HSA-166520]
Vesicle-mediated transport
[NCBI:1269876]
[REACTOME:R-HSA-5653656]
trans-Golgi Network Vesicle Budding
[NCBI:1269880]
[REACTOME:R-HSA-199992]
[PUBMED:11252894]