full name
isoleucyl-tRNA synthetase

synonyms
IARS1, ILERS, ILRS, IRS, PRO0785, IARS, ENSG00000196305

HGNC
HGNC:5330

Entrez Gene
Gene:3376

ENSEMBL
ENSG00000196305

location
chr: 9
start: 94972489
stop: 95056038
strand: -

OMIM
OMIM:600709: IARS
OMIM:617093: Growth retardation, impaired intellectual development, hypotonia, and hepatopathy

transcripts
NR_073446.1
NM_002161.5
NM_013417.3

pathways
Aminoacyl-tRNA biosynthesis [NCBI:83030] [KEGG:hsa00970] [PUBMED:15314242] [PUBMED:18252769]
Cytosolic tRNA aminoacylation [NCBI:1269710] [REACTOME:R-HSA-379716] [PUBMED:16169847] [PUBMED:14500886] [PUBMED:9878398]
Gene Expression [NCBI:1269649] [REACTOME:R-HSA-74160]
Metabolism [NCBI:1269956] [REACTOME:R-HSA-1430728]
Metabolism of amino acids and derivatives [NCBI:1270158] [REACTOME:R-HSA-71291]
SeMet incorporation into proteins [NCBI:1339155] [REACTOME:R-HSA-2408517] [PUBMED:16661668] [PUBMED:16661782]
Selenoamino acid metabolism [NCBI:1339149] [REACTOME:R-HSA-2408522] [PUBMED:20812787]
tRNA Aminoacylation [NCBI:1269709] [REACTOME:R-HSA-379724] [PUBMED:16125937] [PUBMED:5324173] [PUBMED:18682559] [PUBMED:764868] [PUBMED:1894595] [PUBMED:5324172] [PUBMED:18767960] [PUBMED:182209]