full name
nuclear cap binding protein subunit 1

synonyms
CBP80, NCBP, Sto1, NCBP1, ENSG00000136937

HGNC
HGNC:7658

Entrez Gene
Gene:4686

ENSEMBL
ENSG00000136937

location
chr: 9
start: 100395705
stop: 100436030
strand: +

transcripts
NM_002486.4

pathways
Abortive elongation of HIV-1 transcript in the absence of Tat [NCBI:1269078] [REACTOME:R-HSA-167242] [PUBMED:2825027] [PUBMED:9450929] [PUBMED:10199401]
Cleavage of Growing Transcript in the Termination Region [NCBI:1269686] [REACTOME:R-HSA-109688]
Disease [NCBI:1268854] [REACTOME:R-HSA-1643685]
Diseases of signal transduction [NCBI:1268855] [REACTOME:R-HSA-5663202] [PUBMED:12509752]
FGFR2 alternative splicing [NCBI:1383022] [REACTOME:R-HSA-6803529] [PUBMED:17959601] [PUBMED:9858549] [PUBMED:12393912] [PUBMED:10982855] [PUBMED:11313454] [PUBMED:10938105] [PUBMED:16603716] [PUBMED:16449636] [PUBMED:7651400] [PUBMED:19285943] [PUBMED:18573884] [PUBMED:15863030] [PUBMED:15684416] [PUBMED:8668531] [PUBMED:12419237]
FGFR2 mutant receptor activation [NCBI:1268870] [REACTOME:R-HSA-1839126] [PUBMED:15282208] [PUBMED:17552943] [PUBMED:9266968] [PUBMED:17803937] [PUBMED:9816310] [PUBMED:18757403] [PUBMED:11003564] [PUBMED:20101236] [PUBMED:18337450] [PUBMED:9538690] [PUBMED:17525745] [PUBMED:10626794] [PUBMED:11056689] [PUBMED:18381441] [PUBMED:11325814] [PUBMED:9539778] [PUBMED:19103595] [PUBMED:9154000] [PUBMED:20106510] [PUBMED:17505008] [PUBMED:18552176]
Formation of HIV elongation complex in the absence of HIV Tat [NCBI:1269080] [REACTOME:R-HSA-167152]
Formation of HIV-1 elongation complex containing HIV-1 Tat [NCBI:1269077] [REACTOME:R-HSA-167200] [PUBMED:7853496] [PUBMED:14701750] [PUBMED:9491887] [PUBMED:15564463] [PUBMED:10757782]
Formation of RNA Pol II elongation complex [NCBI:1269684] [REACTOME:R-HSA-112382] [PUBMED:12676794]
Formation of the Early Elongation Complex [NCBI:1269683] [REACTOME:R-HSA-113418] [PUBMED:11940650] [PUBMED:10916156]
Formation of the HIV-1 Early Elongation Complex [NCBI:1269075] [REACTOME:R-HSA-167158] [PUBMED:12653964] [PUBMED:12370301] [PUBMED:11940650]
Gene Expression [NCBI:1269649] [REACTOME:R-HSA-74160]
HIV Infection [NCBI:1269057] [REACTOME:R-HSA-162906] [PUBMED:16354571] [PUBMED:9759480]
HIV Life Cycle [NCBI:1269058] [REACTOME:R-HSA-162587] [PUBMED:9188609] [PUBMED:9759480]
HIV Transcription Elongation [NCBI:1269074] [REACTOME:R-HSA-167169] [PUBMED:10550206] [PUBMED:15049426]
Infectious disease [NCBI:1269056] [REACTOME:R-HSA-5663205]
Late Phase of HIV Life Cycle [NCBI:1269069] [REACTOME:R-HSA-162599] [PUBMED:2825027] [PUBMED:10550206] [PUBMED:10562489] [PUBMED:15719065] [PUBMED:15183343] [PUBMED:3031512] [PUBMED:9891806] [PUBMED:2784194]
Metabolism of non-coding RNA [NCBI:1269731] [REACTOME:R-HSA-194441]
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) [NCBI:1269717] [REACTOME:R-HSA-975957] [PUBMED:19859661] [PUBMED:21496649] [PUBMED:17352659] [PUBMED:20795950] [PUBMED:19359157] [PUBMED:17531985] [PUBMED:17671086] [PUBMED:19410547]
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) [NCBI:1269718] [REACTOME:R-HSA-975956] [PUBMED:20795950] [PUBMED:18447580] [PUBMED:17671086] [PUBMED:17531985] [PUBMED:19359157] [PUBMED:19859661] [PUBMED:17352659] [PUBMED:18447585] [PUBMED:18256688]
Nonsense-Mediated Decay (NMD) [NCBI:1269716] [REACTOME:R-HSA-927802] [PUBMED:18524595] [PUBMED:17671086] [PUBMED:19359157] [PUBMED:17531985] [PUBMED:17352659] [PUBMED:21496649] [PUBMED:19859661] [PUBMED:20795950] [PUBMED:19010255]
Processing of Capped Intron-Containing Pre-mRNA [NCBI:1269688] [REACTOME:R-HSA-72203]
Processing of Capped Intronless Pre-mRNA [NCBI:1269699] [REACTOME:R-HSA-75067] [PUBMED:11031238] [PUBMED:12242288] [PUBMED:12408966] [PUBMED:10571029] [PUBMED:7597053]
Processing of Intronless Pre-mRNAs [NCBI:1269702] [REACTOME:R-HSA-77595] [PUBMED:11909521]
RNA Polymerase II Pre-transcription Events [NCBI:1269676] [REACTOME:R-HSA-674695]
RNA Polymerase II Transcription [NCBI:1269675] [REACTOME:R-HSA-73857]
RNA Polymerase II Transcription Elongation [NCBI:1269682] [REACTOME:R-HSA-75955] [PUBMED:11018013] [PUBMED:12676794] [PUBMED:14550628]
RNA Polymerase II Transcription Termination [NCBI:1269685] [REACTOME:R-HSA-73856]
RNA polymerase II transcribes snRNA genes [NCBI:1383088] [REACTOME:R-HSA-6807505] [PUBMED:23932780] [PUBMED:18482001] [PUBMED:20659008] [PUBMED:3837185] [PUBMED:18442490] [PUBMED:24097444] [PUBMED:18631122] [PUBMED:18378697] [PUBMED:6201719] [PUBMED:22622228] [PUBMED:11390411] [PUBMED:25882383]
RNA transport [NCBI:177876] [KEGG:hsa03013] [PUBMED:10872469] [PUBMED:17401408] [PUBMED:20733056] [PUBMED:11018020] [PUBMED:15519698] [PUBMED:16314458] [PUBMED:15901496] [PUBMED:9548260] [PUBMED:18313922]
SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs [NCBI:1269700] [REACTOME:R-HSA-77588] [PUBMED:8479907] [PUBMED:2017161]
SLBP independent Processing of Histone Pre-mRNAs [NCBI:1269701] [REACTOME:R-HSA-111367]
Signal Transduction [NCBI:1269379] [REACTOME:R-HSA-162582] [PUBMED:17604717] [PUBMED:19648010] [PUBMED:16260143] [PUBMED:11742412] [PUBMED:19536106] [PUBMED:15863030] [PUBMED:19379690] [PUBMED:19458711] [PUBMED:19935667] [PUBMED:21252999] [PUBMED:15520807] [PUBMED:17496910] [PUBMED:15450248] [PUBMED:18043707] [PUBMED:16939974] [PUBMED:19762341] [PUBMED:18483217] [PUBMED:17084981] [PUBMED:21781017] [PUBMED:19619488]
Signaling by FGFR [NCBI:1269386] [REACTOME:R-HSA-190236] [PUBMED:15863038] [PUBMED:12080084] [PUBMED:20602996] [PUBMED:15863030] [PUBMED:15567848] [PUBMED:7917292] [PUBMED:19247306] [PUBMED:16597617]
Signaling by FGFR in disease [NCBI:1268863] [REACTOME:R-HSA-1226099] [PUBMED:17552943] [PUBMED:10053006] [PUBMED:8640234] [PUBMED:9865713] [PUBMED:21367659] [PUBMED:10471491] [PUBMED:21711248] [PUBMED:9538690] [PUBMED:20094046] [PUBMED:9539778] [PUBMED:12461689] [PUBMED:9438390] [PUBMED:8841188] [PUBMED:11055896] [PUBMED:8599935] [PUBMED:21160078] [PUBMED:9207791] [PUBMED:9154000] [PUBMED:18381441] [PUBMED:20179196] [PUBMED:8755573] [PUBMED:20226962] [PUBMED:8798788] [PUBMED:19066716] [PUBMED:17505008] [PUBMED:11429702]
Signaling by FGFR2 [NCBI:1269399] [REACTOME:R-HSA-5654738] [PUBMED:19247306] [PUBMED:16597617] [PUBMED:15863038] [PUBMED:12080084] [PUBMED:15863030] [PUBMED:20602996] [PUBMED:15567848] [PUBMED:7917292]
Signaling by FGFR2 IIIa TM [NCBI:1383045] [REACTOME:R-HSA-8851708] [PUBMED:21355848]
Signaling by FGFR2 in disease [NCBI:1268869] [REACTOME:R-HSA-5655253] [PUBMED:9154000] [PUBMED:17505008] [PUBMED:17552943] [PUBMED:21367659] [PUBMED:21711248] [PUBMED:9538690] [PUBMED:18381441] [PUBMED:19147536]
Spliceosome [NCBI:125136] [KEGG:hsa03040] [PUBMED:10978320] [PUBMED:19239890] [PUBMED:19733268] [PUBMED:17537823]
Tat-mediated elongation of the HIV-1 transcript [NCBI:1269076] [REACTOME:R-HSA-167246] [PUBMED:2825027] [PUBMED:9450929] [PUBMED:11940650] [PUBMED:2476805] [PUBMED:10866664] [PUBMED:10757782] [PUBMED:10550206] [PUBMED:10199401] [PUBMED:15719065] [PUBMED:10562489] [PUBMED:15183343] [PUBMED:14701750] [PUBMED:7853496] [PUBMED:9491887]
Transcription of the HIV genome [NCBI:1269070] [REACTOME:R-HSA-167172] [PUBMED:10550206] [PUBMED:9791012]
Transport of Mature Transcript to Cytoplasm [NCBI:1269693] [REACTOME:R-HSA-72202]
Transport of Mature mRNA Derived from an Intronless Transcript [NCBI:1269698] [REACTOME:R-HSA-159231]
Transport of Mature mRNA derived from an Intron-Containing Transcript [NCBI:1269694] [REACTOME:R-HSA-159236]
Transport of Mature mRNAs Derived from Intronless Transcripts [NCBI:1269695] [REACTOME:R-HSA-159234]
Transport of the SLBP Dependant Mature mRNA [NCBI:1269696] [REACTOME:R-HSA-159230]
Transport of the SLBP independent Mature mRNA [NCBI:1269697] [REACTOME:R-HSA-159227]
mRNA 3'-end processing [NCBI:1269692] [REACTOME:R-HSA-72187] [PUBMED:10371034] [PUBMED:10357856] [PUBMED:2408761] [PUBMED:11909521]
mRNA Capping [NCBI:1269687] [REACTOME:R-HSA-72086] [PUBMED:11909521] [PUBMED:3326038] [PUBMED:10395561] [PUBMED:11017188]
mRNA Splicing [NCBI:1269689] [REACTOME:R-HSA-72172] [PUBMED:12226669]
mRNA Splicing - Major Pathway [NCBI:1269690] [REACTOME:R-HSA-72163]
mRNA Splicing - Minor Pathway [NCBI:1269691] [REACTOME:R-HSA-72165] [PUBMED:10207048] [PUBMED:9149533]
mRNA surveillance pathway [NCBI:193328] [KEGG:hsa03015] [PUBMED:16723977] [PUBMED:18158581] [PUBMED:16715045] [PUBMED:17183357] [PUBMED:15040442]
snRNP Assembly [NCBI:1269732] [REACTOME:R-HSA-191859] [PUBMED:15130578]