full name
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2

synonyms
HSD3B, HSDB, SDR11E2, HSD3B2, ENSG00000203859

HGNC
HGNC:5218

Entrez Gene
Gene:3284

ENSEMBL
ENSG00000203859

location
chr: 1
start: 119957554
stop: 119965662
strand: +

OMIM
OMIM:613890: HSD3B2
OMIM:201810: Adrenal hyperplasia, congenital, due to 3-beta-hydroxysteroid dehydrogenase 2 deficiency

transcripts
NM_001166120.1
NM_000198.3

pathways
Aldosterone synthesis and secretion [NCBI:1272485] [KEGG:hsa04925] [PUBMED:15044681] [PUBMED:10536682] [PUBMED:24944029] [PUBMED:25788893] [PUBMED:15026188] [PUBMED:22689262] [PUBMED:22364774] [PUBMED:18406824] [PUBMED:14645496] [PUBMED:21839803] [PUBMED:22395411] [PUBMED:23628605] [PUBMED:21962440]
Androgen biosynthesis [NCBI:1270050] [REACTOME:R-HSA-193048] [PUBMED:12428201]
C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone [NCBI:413383] [KEGG:hsa_M00110]
Glucocorticoid biosynthesis [NCBI:1270048] [REACTOME:R-HSA-194002] [PUBMED:15583024]
Metabolic pathways [NCBI:132956] [KEGG:hsa01100]
Metabolism [NCBI:1269956] [REACTOME:R-HSA-1430728]
Metabolism of lipids and lipoproteins [NCBI:1270001] [REACTOME:R-HSA-556833]
Metabolism of steroid hormones [NCBI:1270046] [REACTOME:R-HSA-196071] [PUBMED:15583024]
Mineralocorticoid biosynthesis [NCBI:1270049] [REACTOME:R-HSA-193993] [PUBMED:15583024]
Ovarian steroidogenesis [NCBI:790011] [KEGG:hsa04913] [PUBMED:11883103] [PUBMED:11408113] [PUBMED:16603089] [PUBMED:15831519] [PUBMED:11447221] [PUBMED:20628033] [PUBMED:10630400] [PUBMED:18440223] [PUBMED:20937107] [PUBMED:11704115] [PUBMED:17003287] [PUBMED:17008391] [PUBMED:15541573] [PUBMED:21862696] [PUBMED:16414178] [PUBMED:14769828]
Steroid hormone biosynthesis [NCBI:82940] [KEGG:hsa00140] [PUBMED:15642792] [PUBMED:16413106] [PUBMED:12832414] [PUBMED:17475203] [PUBMED:12604236] [PUBMED:10998348] [PUBMED:11469811] [PUBMED:16547389] [PUBMED:17926129] [PUBMED:17459698]
Steroid hormone biosynthesis, cholesterol => prognenolone => progesterone [NCBI:413396] [KEGG:hsa_M00107]