full name
aminolevulinate dehydratase

synonyms
ALADH, PBGS, ALAD, ENSG00000148218

HGNC
HGNC:395

Entrez Gene
Gene:210

ENSEMBL
ENSG00000148218

location
chr: 9
start: 116148592
stop: 116163618
strand: -

OMIM
OMIM:125270: ALAD (Autosomal recessive inheritance)
OMIM:612740: Porphyria, acute hepatic
OMIM:612740: {Lead poisoning, susceptibility to}

transcripts
NM_000031.5

pathways
Heme biosynthesis [NCBI:1270187] [REACTOME:R-HSA-189451] [PUBMED:16839620] [PUBMED:10522552]
Immune System [NCBI:1269170] [REACTOME:R-HSA-168256]
Innate Immune System [NCBI:1269203] [REACTOME:R-HSA-168249]
Metabolic pathways [NCBI:132956] [KEGG:hsa01100]
Metabolism [NCBI:1269956] [REACTOME:R-HSA-1430728]
Metabolism of porphyrins [NCBI:1270186] [REACTOME:R-HSA-189445]
Neutrophil degranulation [NCBI:1457780] [REACTOME:R-HSA-6798695] [PUBMED:20338884] [PUBMED:1378856] [PUBMED:17627888] [PUBMED:23650620] [PUBMED:8692836]
Porphyrin and chlorophyll metabolism [NCBI:83021] [KEGG:hsa00860] [PUBMED:12195810] [PUBMED:11283349] [PUBMED:10217486] [PUBMED:11007789] [PUBMED:10518530] [PUBMED:12055304] [PUBMED:12196148] [PUBMED:17506685] [PUBMED:16245042] [PUBMED:23922391] [PUBMED:23042036] [PUBMED:9461500]
heme biosynthesis [NCBI:545289] [BIOCYC:HUMAN_PWY-5920] [PUBMED:6769048] [PUBMED:7592564] [PUBMED:3816774] [PUBMED:20506125] [PUBMED:23471474] [PUBMED:9564029] [PUBMED:7592562] [PUBMED:3346226]
tetrapyrrole biosynthesis [NCBI:142231] [BIOCYC:HUMAN_PWY-5189] [PUBMED:16564539] [PUBMED:6769048] [PUBMED:17227226]