full name
phosphoglycerate dehydrogenase

synonyms
3-PGDH, 3PGDH, PDG, PGAD, PGD, PGDH, SERA, PHGDH, ENSG00000092621

HGNC
HGNC:8923

Entrez Gene
Gene:26227

ENSEMBL
ENSG00000092621

location
chr: 1
start: 120254419
stop: 120286849
strand: +

OMIM
OMIM:606879: PHGDH (Autosomal recessive inheritance)
OMIM:256520: Neu-Laxova syndrome 1
OMIM:601815: Phosphoglycerate dehydrogenase deficiency

transcripts
NM_006623.3

pathways
Amino acid synthesis and interconversion (transamination) [NCBI:1270159] [REACTOME:R-HSA-70614]
Biosynthesis of amino acids [NCBI:790012] [KEGG:hsa01230]
Carbon metabolism [NCBI:814926] [KEGG:hsa01200]
Glycine, serine and threonine metabolism [NCBI:82949] [KEGG:hsa00260] [PUBMED:7639721] [PUBMED:15520012] [PUBMED:11823218] [PUBMED:15470257] [PUBMED:10473374] [PUBMED:16707670] [PUBMED:17636255] [PUBMED:11341914]
Metabolic pathways [NCBI:132956] [KEGG:hsa01100]
Metabolism [NCBI:1269956] [REACTOME:R-HSA-1430728]
Metabolism of amino acids and derivatives [NCBI:1270158] [REACTOME:R-HSA-71291]
Serine biosynthesis [NCBI:1270160] [REACTOME:R-HSA-977347] [PUBMED:15021249]
Serine biosynthesis, glycerate-3P => serine [NCBI:413350] [KEGG:hsa_M00020]