full name
syntaxin binding protein 1

synonyms
MUNC18-1, NSEC1, P67, RBSEC1, UNC18, STXBP1, ENSG00000136854

HGNC
HGNC:11444

Entrez Gene
Gene:6812

ENSEMBL
ENSG00000136854

location
chr: 9
start: 130374486
stop: 130454995
strand: +

OMIM
OMIM:602926: STXBP1 (Autosomal dominant inheritance)
OMIM:612164: Epileptic encephalopathy, early infantile, 4

transcripts
NM_003165.3
NM_001032221.3

pathways
Acetylcholine Neurotransmitter Release Cycle [NCBI:1268773] [REACTOME:R-HSA-264642] [PUBMED:18029057]
Dopamine Neurotransmitter Release Cycle [NCBI:1268772] [REACTOME:R-HSA-212676] [PUBMED:16613554]
Effects of Botulinum toxin [NCBI:138028] [Pathway Interaction Database:botulinumtoxinpathway] [PUBMED:10582602] [PUBMED:8175689] [PUBMED:9783260] [PUBMED:8051110] [PUBMED:9886085] [PUBMED:7737992] [PUBMED:12089155] [PUBMED:8223654] [PUBMED:16052212] [PUBMED:15218059] [PUBMED:8505288] [PUBMED:15489225] [PUBMED:15935055] [PUBMED:14504267] [PUBMED:8103915] [PUBMED:7527117] [PUBMED:15123599] [PUBMED:9712688] [PUBMED:9252191]
GABA synthesis, release, reuptake and degradation [NCBI:1268774] [REACTOME:R-HSA-888590] [PUBMED:19428801] [PUBMED:16787421]
Glutamate Neurotransmitter Release Cycle [NCBI:1268771] [REACTOME:R-HSA-210500] [PUBMED:8825650] [PUBMED:11001057] [PUBMED:16990140] [PUBMED:10440375] [PUBMED:16704978] [PUBMED:17478680] [PUBMED:9701566]
Integration of energy metabolism [NCBI:1270101] [REACTOME:R-HSA-163685] [PUBMED:15509864] [PUBMED:12721358] [PUBMED:12626323]
Interactions of neurexins and neuroligins at synapses [NCBI:1427850] [REACTOME:R-HSA-6794361] [PUBMED:22424845] [PUBMED:23559421] [PUBMED:21155806] [PUBMED:17299456] [PUBMED:17275284]
Metabolism [NCBI:1269956] [REACTOME:R-HSA-1430728]
Neuronal System [NCBI:1268763] [REACTOME:R-HSA-112316]
Neurotransmitter Release Cycle [NCBI:1268768] [REACTOME:R-HSA-112310] [PUBMED:15217342] [PUBMED:16819626] [PUBMED:17880890] [PUBMED:16865347]
Norepinephrine Neurotransmitter Release Cycle [NCBI:1268769] [REACTOME:R-HSA-181430] [PUBMED:17891149] [PUBMED:17478680] [PUBMED:12519779]
Protein-protein interactions at synapses [NCBI:1427849] [REACTOME:R-HSA-6794362] [PUBMED:18923512] [PUBMED:16337696] [PUBMED:17299456]
Regulation of insulin secretion [NCBI:1270102] [REACTOME:R-HSA-422356] [PUBMED:18200017] [PUBMED:11078440] [PUBMED:16321791] [PUBMED:11815463] [PUBMED:16556766]
Serotonin Neurotransmitter Release Cycle [NCBI:1268770] [REACTOME:R-HSA-181429]
Synaptic vesicle cycle [NCBI:373900] [KEGG:hsa04721] [PUBMED:20634814] [PUBMED:17767192] [PUBMED:12094216] [PUBMED:16990140] [PUBMED:18726177] [PUBMED:18275379] [PUBMED:12827282] [PUBMED:12154365] [PUBMED:10212473] [PUBMED:15217342] [PUBMED:7791897] [PUBMED:12563290]
Transmission across Chemical Synapses [NCBI:1268766] [REACTOME:R-HSA-112315]