full name
cyclin dependent kinase 9

synonyms
C-2k, CDC2L4, CTK1, PITALRE, TAK, CDK9, ENSG00000136807

HGNC
HGNC:1780

Entrez Gene
Gene:1025

ENSEMBL
ENSG00000136807

location
chr: 9
start: 130548305
stop: 130553052
strand: +

transcripts
NM_001261.3

pathways
Disease [NCBI:1268854] [REACTOME:R-HSA-1643685]
Formation of HIV elongation complex in the absence of HIV Tat [NCBI:1269080] [REACTOME:R-HSA-167152]
Formation of HIV-1 elongation complex containing HIV-1 Tat [NCBI:1269077] [REACTOME:R-HSA-167200] [PUBMED:7853496] [PUBMED:14701750] [PUBMED:9491887] [PUBMED:15564463] [PUBMED:10757782]
Formation of RNA Pol II elongation complex [NCBI:1269684] [REACTOME:R-HSA-112382] [PUBMED:12676794]
Gene Expression [NCBI:1269649] [REACTOME:R-HSA-74160]
Generic Transcription Pathway [NCBI:1269650] [REACTOME:R-HSA-212436] [PUBMED:15175151] [PUBMED:14744435] [PUBMED:15680972] [PUBMED:11395415] [PUBMED:15896744] [PUBMED:10235266] [PUBMED:14986688] [PUBMED:12023297] [PUBMED:15680973] [PUBMED:16751179] [PUBMED:11861166] [PUBMED:16429119] [PUBMED:16719718] [PUBMED:16921404] [PUBMED:15690163]
HIV Infection [NCBI:1269057] [REACTOME:R-HSA-162906] [PUBMED:16354571] [PUBMED:9759480]
HIV Life Cycle [NCBI:1269058] [REACTOME:R-HSA-162587] [PUBMED:9188609] [PUBMED:9759480]
HIV Transcription Elongation [NCBI:1269074] [REACTOME:R-HSA-167169] [PUBMED:10550206] [PUBMED:15049426]
HIV elongation arrest and recovery [NCBI:1269079] [REACTOME:R-HSA-167287]
Host Interactions of HIV factors [NCBI:1269091] [REACTOME:R-HSA-162909]
Infectious disease [NCBI:1269056] [REACTOME:R-HSA-5663205]
Interactions of Tat with host cellular proteins [NCBI:1269099] [REACTOME:R-HSA-176034] [PUBMED:7853496] [PUBMED:9491887]
Late Phase of HIV Life Cycle [NCBI:1269069] [REACTOME:R-HSA-162599] [PUBMED:2825027] [PUBMED:10550206] [PUBMED:10562489] [PUBMED:15719065] [PUBMED:15183343] [PUBMED:3031512] [PUBMED:9891806] [PUBMED:2784194]
Pausing and recovery of HIV elongation [NCBI:1269081] [REACTOME:R-HSA-167290]
Pausing and recovery of Tat-mediated HIV elongation [NCBI:1269083] [REACTOME:R-HSA-167238]
RNA Polymerase II Pre-transcription Events [NCBI:1269676] [REACTOME:R-HSA-674695]
RNA Polymerase II Transcription [NCBI:1269675] [REACTOME:R-HSA-73857]
RNA Polymerase II Transcription Elongation [NCBI:1269682] [REACTOME:R-HSA-75955] [PUBMED:11018013] [PUBMED:12676794] [PUBMED:14550628]
RNA polymerase II transcribes snRNA genes [NCBI:1383088] [REACTOME:R-HSA-6807505] [PUBMED:23932780] [PUBMED:18482001] [PUBMED:20659008] [PUBMED:3837185] [PUBMED:18442490] [PUBMED:24097444] [PUBMED:18631122] [PUBMED:18378697] [PUBMED:6201719] [PUBMED:22622228] [PUBMED:11390411] [PUBMED:25882383]
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription [NCBI:1269528] [REACTOME:R-HSA-2173796] [PUBMED:22275377] [PUBMED:18568018] [PUBMED:15150273] [PUBMED:10934479] [PUBMED:11294908] [PUBMED:12592392] [PUBMED:10022869] [PUBMED:14657019] [PUBMED:11013220] [PUBMED:11274402] [PUBMED:19914168] [PUBMED:12150994]
Signal Transduction [NCBI:1269379] [REACTOME:R-HSA-162582] [PUBMED:17604717] [PUBMED:19648010] [PUBMED:16260143] [PUBMED:11742412] [PUBMED:19536106] [PUBMED:15863030] [PUBMED:19379690] [PUBMED:19458711] [PUBMED:19935667] [PUBMED:21252999] [PUBMED:15520807] [PUBMED:17496910] [PUBMED:15450248] [PUBMED:18043707] [PUBMED:16939974] [PUBMED:19762341] [PUBMED:18483217] [PUBMED:17084981] [PUBMED:21781017] [PUBMED:19619488]
Signaling by TGF-beta Receptor Complex [NCBI:1269523] [REACTOME:R-HSA-170834] [PUBMED:19648010]
TP53 Regulates Transcription of DNA Repair Genes [NCBI:1383075] [REACTOME:R-HSA-6796648] [PUBMED:10984493] [PUBMED:25712099] [PUBMED:22988298] [PUBMED:12771027] [PUBMED:23139867] [PUBMED:11971958] [PUBMED:22012619] [PUBMED:11988847] [PUBMED:9858527] [PUBMED:26773055] [PUBMED:15781865] [PUBMED:11350971] [PUBMED:25429106] [PUBMED:12170774] [PUBMED:20096807] [PUBMED:18187580] [PUBMED:9063748] [PUBMED:24662513]
Tat-mediated HIV elongation arrest and recovery [NCBI:1269082] [REACTOME:R-HSA-167243]
Tat-mediated elongation of the HIV-1 transcript [NCBI:1269076] [REACTOME:R-HSA-167246] [PUBMED:2825027] [PUBMED:9450929] [PUBMED:11940650] [PUBMED:2476805] [PUBMED:10866664] [PUBMED:10757782] [PUBMED:10550206] [PUBMED:10199401] [PUBMED:15719065] [PUBMED:10562489] [PUBMED:15183343] [PUBMED:14701750] [PUBMED:7853496] [PUBMED:9491887]
Transcription of the HIV genome [NCBI:1269070] [REACTOME:R-HSA-167172] [PUBMED:10550206] [PUBMED:9791012]
Transcriptional Regulation by TP53 [NCBI:1269654] [REACTOME:R-HSA-3700989] [PUBMED:26122615] [PUBMED:19410540]
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer [NCBI:1269527] [REACTOME:R-HSA-2173793] [PUBMED:12150994] [PUBMED:16751101] [PUBMED:10199400] [PUBMED:18568018] [PUBMED:19135894] [PUBMED:10531062]
Transcriptional misregulation in cancer [NCBI:523016] [KEGG:hsa05202] [PUBMED:17327229] [PUBMED:20190806] [PUBMED:20145147] [PUBMED:11313274] [PUBMED:11863357] [PUBMED:19472090] [PUBMED:18330902] [PUBMED:19738075] [PUBMED:15024077] [PUBMED:12032780] [PUBMED:14630078] [PUBMED:21765642] [PUBMED:19564705] [PUBMED:17101797] [PUBMED:15160934] [PUBMED:15688424] [PUBMED:15985538] [PUBMED:12527902] [PUBMED:12511414] [PUBMED:11607818] [PUBMED:17222504] [PUBMED:15826838] [PUBMED:21747944] [PUBMED:19406209] [PUBMED:10350329] [PUBMED:21779514] [PUBMED:18563191] [PUBMED:16946003] [PUBMED:17250957] [PUBMED:12670461] [PUBMED:12529654] [PUBMED:18855877] [PUBMED:17505060] [PUBMED:20153925] [PUBMED:20490326] [PUBMED:12130514] [PUBMED:18648544] [PUBMED:19855079] [PUBMED:10717473] [PUBMED:20478527] [PUBMED:11340171] [PUBMED:16169901] [PUBMED:14998494] [PUBMED:19233641] [PUBMED:19133982] [PUBMED:12393465] [PUBMED:19059936] [PUBMED:18172298] [PUBMED:10500199] [PUBMED:19141473] [PUBMED:10537274] [PUBMED:15156184] [PUBMED:14701735] [PUBMED:19422821] [PUBMED:21518926] [PUBMED:18850010] [PUBMED:19075677] [PUBMED:18457914] [PUBMED:12527906] [PUBMED:15644444] [PUBMED:10784387] [PUBMED:17024155] [PUBMED:19075268] [PUBMED:15826834] [PUBMED:21849159] [PUBMED:21123453] [PUBMED:20974671] [PUBMED:20863376]