full name
dolichyl-phosphate mannosyltransferase subunit 2, regulatory

synonyms
CDG1U, DPM2, ENSG00000136908

HGNC
HGNC:3006

Entrez Gene
Gene:8818

ENSEMBL
ENSG00000136908

location
chr: 9
start: 130697374
stop: 130700763
strand: -

OMIM
OMIM:603564: DPM2 (Autosomal recessive inheritance)
OMIM:615042: Congenital disorder of glycosylation, type Iu

transcripts
NM_003863.3

pathways
Asparagine N-linked glycosylation [NCBI:1268714] [REACTOME:R-HSA-446203] [PUBMED:16807922] [PUBMED:19647993] [PUBMED:10580125] [PUBMED:19616933] [PUBMED:20301507] [PUBMED:20301244]
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein [NCBI:1268715] [REACTOME:R-HSA-446193] [PUBMED:20301507]
Glycosylphosphatidylinositol (GPI)-anchor biosynthesis [NCBI:82988] [KEGG:hsa00563] [PUBMED:8253761] [PUBMED:14517336] [PUBMED:12655644] [PUBMED:10329735] [PUBMED:15635094] [PUBMED:14734546] [PUBMED:11102867] [PUBMED:12802054] [PUBMED:15623507] [PUBMED:12807000]
Metabolic pathways [NCBI:132956] [KEGG:hsa01100]
Metabolism of proteins [NCBI:1268677] [REACTOME:R-HSA-392499]
N-Glycan biosynthesis [NCBI:82975] [KEGG:hsa00510] [PUBMED:12684507] [PUBMED:16878994] [PUBMED:11278778] [PUBMED:9111134] [PUBMED:12200473] [PUBMED:15987956]
Post-translational modification: synthesis of GPI-anchored proteins [NCBI:1268710] [REACTOME:R-HSA-163125]
Post-translational protein modification [NCBI:1268701] [REACTOME:R-HSA-597592]
Synthesis of dolichyl-phosphate mannose [NCBI:1268711] [REACTOME:R-HSA-162699] [PUBMED:10835346] [PUBMED:11102867]
Synthesis of glycosylphosphatidylinositol (GPI) [NCBI:1268712] [REACTOME:R-HSA-162710] [PUBMED:11102867]
Synthesis of substrates in N-glycan biosythesis [NCBI:1268716] [REACTOME:R-HSA-446219] [PUBMED:18597486]
dolichyl-diphosphooligosaccharide biosynthesis [NCBI:142200] [BIOCYC:HUMAN_MANNOSYL-CHITO-DOLICHOL-BIOSYNTHESIS]