full name
kynurenine aminotransferase 1

synonyms
GTK, KAT1, KATI, CCBL1, KYAT1, ENSG00000171097

HGNC
HGNC:1564

Entrez Gene
Gene:883

ENSEMBL
ENSG00000171097

location
chr: 9
start: 131595392
stop: 131644354
strand: -

transcripts
NM_001122671.1
NM_001122672.1
NM_004059.4

pathways
Amino acid synthesis and interconversion (transamination) [NCBI:1270159] [REACTOME:R-HSA-70614]
Chemical carcinogenesis [NCBI:673221] [KEGG:hsa05204] [PUBMED:21473878] [PUBMED:15489140] [PUBMED:21255676] [PUBMED:11376689] [PUBMED:15298956] [PUBMED:17445838] [PUBMED:22705365] [PUBMED:9152590] [PUBMED:8759017] [PUBMED:20570348] [PUBMED:11275476] [PUBMED:9202760] [PUBMED:21163908] [PUBMED:10753215] [PUBMED:10913381] [PUBMED:21217854] [PUBMED:15582261] [PUBMED:16959879] [PUBMED:11092599] [PUBMED:20159989] [PUBMED:21234336] [PUBMED:17459420] [PUBMED:9275165] [PUBMED:17292678] [PUBMED:11978484] [PUBMED:11222868] [PUBMED:15660110] [PUBMED:8702479] [PUBMED:9356303] [PUBMED:20232918] [PUBMED:12435844] [PUBMED:19657920] [PUBMED:8951235] [PUBMED:15532073] [PUBMED:16084004] [PUBMED:18066431] [PUBMED:14570033] [PUBMED:16421178] [PUBMED:21154658] [PUBMED:12928348] [PUBMED:19531241] [PUBMED:20669524] [PUBMED:11467078] [PUBMED:22178655] [PUBMED:21456541]
Histidine, lysine, phenylalanine, tyrosine, proline and tryptophan catabolism [NCBI:1309221] [REACTOME:R-HSA-6788656]
L-kynurenine degradation [NCBI:907939] [BIOCYC:HUMAN_PWY-6309] [PUBMED:15018833] [PUBMED:18182052] [PUBMED:9784247] [PUBMED:18032661] [PUBMED:9291104] [PUBMED:18282734] [PUBMED:18220779] [PUBMED:16942634] [PUBMED:2384749] [PUBMED:19141084] [PUBMED:8764597] [PUBMED:18027945] [PUBMED:19268309] [PUBMED:12763538]
Metabolic pathways [NCBI:132956] [KEGG:hsa01100]
Metabolism [NCBI:1269956] [REACTOME:R-HSA-1430728]
Metabolism of amino acids and derivatives [NCBI:1270158] [REACTOME:R-HSA-71291]
Phenylalanine and tyrosine catabolism [NCBI:1270164] [REACTOME:R-HSA-71182]
Selenocompound metabolism [NCBI:82969] [KEGG:hsa00450] [PUBMED:20383543] [PUBMED:21190829] [PUBMED:19051051] [PUBMED:11782468] [PUBMED:17451884]
Tryptophan catabolism [NCBI:1270166] [REACTOME:R-HSA-71240] [PUBMED:1772073]
Tryptophan metabolism [NCBI:82964] [KEGG:hsa00380] [PUBMED:15749753]
glutathione-mediated detoxification [NCBI:142435] [BIOCYC:HUMAN_PWY-4061] [PUBMED:4892500] [PUBMED:4024656] [PUBMED:9755286] [PUBMED:15627473] [PUBMED:5627473] [PUBMED:11876405] [PUBMED:12480900] [PUBMED:9045797]