full name
transcription termination factor 1

synonyms
TTF-1, TTF-I, TTF1, ENSG00000125482

HGNC
HGNC:12397

Entrez Gene
Gene:7270

ENSEMBL
ENSG00000125482

location
chr: 9
start: 135250935
stop: 135282238
strand: -

transcripts
NM_001205296.1
NM_007344.3

pathways
Defective pro-SFTPB causes pulmonary surfactant metabolism dysfunction 1 (SMDP1) and respiratory distress syndrome (RDS) [NCBI:1309211] [REACTOME:R-HSA-5688031] [PUBMED:25621661] [PUBMED:7537464] [PUBMED:19220077] [PUBMED:15049696]
Disease [NCBI:1268854] [REACTOME:R-HSA-1643685]
Diseases associated with surfactant metabolism [NCBI:1309208] [REACTOME:R-HSA-5687613] [PUBMED:25621661]
Diseases of metabolism [NCBI:1268939] [REACTOME:R-HSA-5668914]
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression [NCBI:1383084] [REACTOME:R-HSA-427389] [PUBMED:20026667] [PUBMED:23063748] [PUBMED:17707230] [PUBMED:18948749] [PUBMED:23153826] [PUBMED:23150253] [PUBMED:18631128]
Epigenetic regulation of gene expression [NCBI:1269734] [REACTOME:R-HSA-212165] [PUBMED:12610534]
Gene Expression [NCBI:1269649] [REACTOME:R-HSA-74160]
Metabolism of proteins [NCBI:1268677] [REACTOME:R-HSA-392499]
Negative epigenetic regulation of rRNA expression [NCBI:1269737] [REACTOME:R-HSA-5250941] [PUBMED:23063748] [PUBMED:23150253] [PUBMED:18616426]
NoRC negatively regulates rRNA expression [NCBI:1269739] [REACTOME:R-HSA-427413] [PUBMED:17439825] [PUBMED:17613545] [PUBMED:23063748] [PUBMED:11583633] [PUBMED:18631128] [PUBMED:18616426]
Positive epigenetic regulation of rRNA expression [NCBI:1339125] [REACTOME:R-HSA-5250913] [PUBMED:23153826] [PUBMED:16574391] [PUBMED:23063748] [PUBMED:23150253] [PUBMED:18616426]
RNA Polymerase I Promoter Clearance [NCBI:1269658] [REACTOME:R-HSA-73854]
RNA Polymerase I Transcription [NCBI:1269657] [REACTOME:R-HSA-73864]
RNA Polymerase I Transcription Initiation [NCBI:1269660] [REACTOME:R-HSA-73762]
RNA Polymerase I Transcription Termination [NCBI:1269663] [REACTOME:R-HSA-73863]
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription [NCBI:1269656] [REACTOME:R-HSA-504046]
Surfactant metabolism [NCBI:1309223] [REACTOME:R-HSA-5683826] [PUBMED:20551227] [PUBMED:23026158] [PUBMED:24868212] [PUBMED:23736009] [PUBMED:16423266] [PUBMED:23441475] [PUBMED:19824815] [PUBMED:8162991] [PUBMED:16580255] [PUBMED:19037882]
Thyroid hormone synthesis [NCBI:835410] [KEGG:hsa04918] [PUBMED:21448409] [PUBMED:9086577] [PUBMED:21986207] [PUBMED:11137035] [PUBMED:17666482] [PUBMED:20407074] [PUBMED:20093166] [PUBMED:20122987] [PUBMED:15611820] [PUBMED:20378719] [PUBMED:23438835] [PUBMED:11717564] [PUBMED:16870170] [PUBMED:19196800] [PUBMED:9538302] [PUBMED:11029276] [PUBMED:20167242] [PUBMED:10893432] [PUBMED:21683758]