full name
protein kinase C theta

synonyms
nPKC-theta, PRKCT, PRKCQ, ENSG00000065675

HGNC
HGNC:9410

Entrez Gene
Gene:5588

ENSEMBL
ENSG00000065675

location
chr: 10
start: 6435558
stop: 6622254
strand: -

transcripts
NM_001242413.1
NM_006257.3

pathways
Adaptive Immune System [NCBI:1269171] [REACTOME:R-HSA-1280218] [PUBMED:16551257] [PUBMED:21682741] [PUBMED:11861602]
Adipocytokine signaling pathway [NCBI:83093] [KEGG:hsa04920] [PUBMED:12829246] [PUBMED:10905472] [PUBMED:15980064] [PUBMED:12754525] [PUBMED:12368907] [PUBMED:11557972] [PUBMED:15856064] [PUBMED:9671776] [PUBMED:10766253] [PUBMED:15733744] [PUBMED:15058305] [PUBMED:14716305] [PUBMED:11479627] [PUBMED:14679176]
Apoptosis [NCBI:83060] [KEGG:hsa04210] [NCBI:1270262] [REACTOME:R-HSA-109581] [PUBMED:12189384] [PUBMED:20533903] [PUBMED:18208375] [PUBMED:22429822] [PUBMED:15218528] [PUBMED:24769728] [PUBMED:18023214] [PUBMED:25526085] [PUBMED:23070002] [PUBMED:15654015] [PUBMED:15601572] [PUBMED:14561771] [PUBMED:24278747] [PUBMED:21914490] [PUBMED:22465226] [PUBMED:21145844] [PUBMED:12838338] [PUBMED:18238895] [PUBMED:12949498] [PUBMED:18304445] [PUBMED:14737178] [PUBMED:26231733] [PUBMED:9916983] [PUBMED:14634621] [PUBMED:19770840] [PUBMED:22075987] [PUBMED:4561027] [PUBMED:20075940] [PUBMED:9894605] [PUBMED:26615431] [PUBMED:12505355] [PUBMED:11520933] [PUBMED:19148180] [PUBMED:16397578] [PUBMED:15719025] [PUBMED:15322527] [PUBMED:15725726] [PUBMED:12209154] [PUBMED:23803157]
Apoptotic cleavage of cellular proteins [NCBI:1270288] [REACTOME:R-HSA-111465] [PUBMED:17254298] [PUBMED:17599937] [PUBMED:12655297]
Apoptotic execution phase [NCBI:1270287] [REACTOME:R-HSA-75153] [PUBMED:12655297]
Autophagy - animal [NCBI:83058] [KEGG:hsa04140] [PUBMED:16200202] [PUBMED:15325588] [PUBMED:24343578] [PUBMED:15978794] [PUBMED:19802558] [PUBMED:16099218] [PUBMED:11099404] [PUBMED:19653858] [PUBMED:15325584] [PUBMED:20034776] [PUBMED:15928708] [PUBMED:21801009] [PUBMED:25948417] [PUBMED:16125113] [PUBMED:21187343]
Axon guidance [NCBI:83065] [KEGG:hsa04360] [NCBI:1270303] [REACTOME:R-HSA-422475] [PUBMED:14682358] [PUBMED:15084255] [PUBMED:11687826] [PUBMED:15818466] [PUBMED:15363605] [PUBMED:12471249] [PUBMED:15630019] [PUBMED:11891122] [PUBMED:15960985] [PUBMED:12677003]
Calcineurin-regulated NFAT-dependent transcription in lymphocytes [NCBI:137993] [Pathway Interaction Database:nfat_tfpathway] [PUBMED:11254715] [PUBMED:11356833] [PUBMED:12121669] [PUBMED:10878360] [PUBMED:11786533] [PUBMED:8284217] [PUBMED:10816557] [PUBMED:11956291] [PUBMED:7510691] [PUBMED:9195954] [PUBMED:8240350] [PUBMED:12452838] [PUBMED:8623163] [PUBMED:15834410] [PUBMED:10894164] [PUBMED:10970869] [PUBMED:10755616] [PUBMED:14607827] [PUBMED:12705856] [PUBMED:12086671] [PUBMED:7982959] [PUBMED:9047239] [PUBMED:12374808] [PUBMED:14573767] [PUBMED:12560487] [PUBMED:10570264] [PUBMED:8397339] [PUBMED:12055628] [PUBMED:15308098] [PUBMED:12065418] [PUBMED:7891702] [PUBMED:7749982] [PUBMED:14973438] [PUBMED:8674125] [PUBMED:16873067] [PUBMED:12453415] [PUBMED:8441422] [PUBMED:1737937] [PUBMED:10671476] [PUBMED:8376940] [PUBMED:9545284]
Developmental Biology [NCBI:1270302] [REACTOME:R-HSA-1266738]
Downstream TCR signaling [NCBI:1269176] [REACTOME:R-HSA-202424] [PUBMED:15084594]
Downstream signaling in naive CD8+ T cells [NCBI:138018] [Pathway Interaction Database:cd8tcrdownstreampathway] [PUBMED:293720] [PUBMED:7935374] [PUBMED:12065418] [PUBMED:8566027] [PUBMED:12917261] [PUBMED:8394352] [PUBMED:8441422] [PUBMED:1386920] [PUBMED:8617294] [PUBMED:12732656] [PUBMED:7889942] [PUBMED:1737937] [PUBMED:1381507] [PUBMED:16210616] [PUBMED:11927626] [PUBMED:10477579] [PUBMED:10206983] [PUBMED:8376940] [PUBMED:9395475] [PUBMED:12972619] [PUBMED:8394845] [PUBMED:11485747] [PUBMED:15814665] [PUBMED:14645153] [PUBMED:2119889] [PUBMED:8208531] [PUBMED:10970869] [PUBMED:8612134] [PUBMED:8623163] [PUBMED:16237086] [PUBMED:16585578] [PUBMED:10544201] [PUBMED:8397339] [PUBMED:14605368] [PUBMED:12560487] [PUBMED:7982959]
Effects of PIP2 hydrolysis [NCBI:1269363] [REACTOME:R-HSA-114508] [PUBMED:17157506] [PUBMED:9601053]
Endothelins [NCBI:137958] [Pathway Interaction Database:endothelinpathway] [PUBMED:1319997] [PUBMED:12719447] [PUBMED:15047866] [PUBMED:1905483] [PUBMED:3144974] [PUBMED:12922939] [PUBMED:9595433] [PUBMED:2558572] [PUBMED:10364236] [PUBMED:11231316] [PUBMED:17569879] [PUBMED:11078350] [PUBMED:17535295] [PUBMED:17533154] [PUBMED:8764613] [PUBMED:8617878] [PUBMED:17526654] [PUBMED:8843717] [PUBMED:12606754] [PUBMED:15200122] [PUBMED:8319594] [PUBMED:17627891] [PUBMED:8940174] [PUBMED:12397581] [PUBMED:2545198]
FCERI mediated NF-kB activation [NCBI:1269301] [REACTOME:R-HSA-2871837] [PUBMED:17336609] [PUBMED:16432253]
Fc epsilon receptor (FCERI) signaling [NCBI:1269298] [REACTOME:R-HSA-2454202] [PUBMED:15099567] [PUBMED:21799019]
G alpha (q) signalling events [NCBI:1269578] [REACTOME:R-HSA-416476] [PUBMED:19212139]
G alpha (z) signalling events [NCBI:1269577] [REACTOME:R-HSA-418597] [PUBMED:1908722] [PUBMED:11313909]
GPCR downstream signaling [NCBI:1269574] [REACTOME:R-HSA-388396] [PUBMED:12040175]
Gastrin-CREB signalling pathway via PKC and MAPK [NCBI:1269592] [REACTOME:R-HSA-881907] [PUBMED:10413847] [PUBMED:7491953] [PUBMED:17698287]
Hemostasis [NCBI:1269340] [REACTOME:R-HSA-109582]
Immune System [NCBI:1269170] [REACTOME:R-HSA-168256]
Inactivation, recovery and regulation of the phototransduction cascade [NCBI:1269629] [REACTOME:R-HSA-2514859] [PUBMED:20430952] [PUBMED:22658984]
Inflammatory mediator regulation of TRP channels [NCBI:948277] [KEGG:hsa04750] [PUBMED:21841075] [PUBMED:15820689] [PUBMED:16776582] [PUBMED:12838328] [PUBMED:17548207] [PUBMED:16319926] [PUBMED:18427980] [PUBMED:20932256] [PUBMED:18615141] [PUBMED:17124270] [PUBMED:17684094] [PUBMED:22470230] [PUBMED:19074743] [PUBMED:23000387] [PUBMED:24099085] [PUBMED:17321113]
Innate Immune System [NCBI:1269203] [REACTOME:R-HSA-168249]
Insulin resistance [NCBI:1272486] [KEGG:hsa04931] [PUBMED:17130651] [PUBMED:20466550] [PUBMED:16364488] [PUBMED:12765939] [PUBMED:15166380] [PUBMED:7666792] [PUBMED:16756496] [PUBMED:23647930] [PUBMED:10923637] [PUBMED:17141630] [PUBMED:9886945] [PUBMED:8048519] [PUBMED:18309108] [PUBMED:15107844] [PUBMED:20526383] [PUBMED:22360800] [PUBMED:16186396] [PUBMED:22675355] [PUBMED:22677645]
Measles [NCBI:213306] [KEGG:hsa05162] [PUBMED:16237742] [PUBMED:12804771] [PUBMED:19198562] [PUBMED:20376484] [PUBMED:11385511] [PUBMED:16963735] [PUBMED:19198566] [PUBMED:18922877] [PUBMED:19203114] [PUBMED:12620806] [PUBMED:16690907] [PUBMED:17720800] [PUBMED:20636817] [PUBMED:12410527] [PUBMED:11582511] [PUBMED:19203109] [PUBMED:19203113] [PUBMED:14585342] [PUBMED:12805463]
NF-kappa B signaling pathway [NCBI:634527] [KEGG:hsa04064] [PUBMED:22119011] [PUBMED:16264088] [PUBMED:21187855] [PUBMED:15546385] [PUBMED:17607554] [PUBMED:21135871] [PUBMED:16984817] [PUBMED:17047224] [PUBMED:19203223] [PUBMED:20300215] [PUBMED:14657271] [PUBMED:17431096] [PUBMED:15134788] [PUBMED:16356770] [PUBMED:21772278] [PUBMED:12654254] [PUBMED:22390971] [PUBMED:22017435] [PUBMED:17183360] [PUBMED:21173796] [PUBMED:15905862] [PUBMED:19302050] [PUBMED:17098202] [PUBMED:21872579] [PUBMED:22152226] [PUBMED:18613837] [PUBMED:19489733] [PUBMED:11875461] [PUBMED:19726767] [PUBMED:22017430] [PUBMED:21232019] [PUBMED:18832076]
Netrin-1 signaling [NCBI:1270314] [REACTOME:R-HSA-373752] [PUBMED:18269208] [PUBMED:10499167]
Platelet activation, signaling and aggregation [NCBI:1269350] [REACTOME:R-HSA-76002] [PUBMED:16543958] [PUBMED:8704248] [PUBMED:2018971] [PUBMED:1672265] [PUBMED:17059469] [PUBMED:12681240] [PUBMED:12411949] [PUBMED:11511514]
Programmed Cell Death [NCBI:1270261] [REACTOME:R-HSA-5357801] [PUBMED:25236395]
Role of Calcineurin-dependent NFAT signaling in lymphocytes [NCBI:137953] [Pathway Interaction Database:nfat_3pathway] [PUBMED:15743762] [PUBMED:9109491] [PUBMED:1715244] [PUBMED:15121840] [PUBMED:10195903] [PUBMED:10788511] [PUBMED:9630228] [PUBMED:9834092] [PUBMED:9655484] [PUBMED:10933397] [PUBMED:11030334] [PUBMED:8684469] [PUBMED:10861295] [PUBMED:15117942] [PUBMED:12351631] [PUBMED:15902271] [PUBMED:16406492] [PUBMED:10944115] [PUBMED:10611249] [PUBMED:15733859] [PUBMED:15757646] [PUBMED:9768749] [PUBMED:9072970] [PUBMED:12510191] [PUBMED:9585406] [PUBMED:293720] [PUBMED:12925851] [PUBMED:16943420] [PUBMED:11823475] [PUBMED:16141075] [PUBMED:9374467] [PUBMED:9660798] [PUBMED:7528941] [PUBMED:11356833] [PUBMED:10593895] [PUBMED:10866678] [PUBMED:9171236] [PUBMED:12809556] [PUBMED:10652349] [PUBMED:12021260] [PUBMED:16455648]
Signal Transduction [NCBI:1269379] [REACTOME:R-HSA-162582] [PUBMED:17604717] [PUBMED:19648010] [PUBMED:16260143] [PUBMED:11742412] [PUBMED:19536106] [PUBMED:15863030] [PUBMED:19379690] [PUBMED:19458711] [PUBMED:19935667] [PUBMED:21252999] [PUBMED:15520807] [PUBMED:17496910] [PUBMED:15450248] [PUBMED:18043707] [PUBMED:16939974] [PUBMED:19762341] [PUBMED:18483217] [PUBMED:17084981] [PUBMED:21781017] [PUBMED:19619488]
Signaling by GPCR [NCBI:1269543] [REACTOME:R-HSA-372790] [PUBMED:16902930] [PUBMED:10202136] [PUBMED:18043707]
T cell receptor signaling pathway [NCBI:83080] [KEGG:hsa04660] [PUBMED:17395537] [PUBMED:15308211] [PUBMED:15928679] [PUBMED:14656980] [PUBMED:17187070] [PUBMED:15084594] [PUBMED:16799472] [PUBMED:12669022] [PUBMED:15286727] [PUBMED:15122199] [PUBMED:19132916] [PUBMED:15489916] [PUBMED:11905831] [PUBMED:12195013] [PUBMED:15343367] [PUBMED:12133805] [PUBMED:14647476] [PUBMED:15771581] [PUBMED:15099566] [PUBMED:14617194] [PUBMED:19290929] [PUBMED:15345216]
TCR signaling [NCBI:1269172] [REACTOME:R-HSA-202403] [PUBMED:10375551] [PUBMED:12876557] [PUBMED:9989491]
TCR signaling in naive CD4+ T cells [NCBI:137998] [Pathway Interaction Database:tcr_pathway] [PUBMED:11376344] [PUBMED:9094314] [PUBMED:8083187] [PUBMED:11994416] [PUBMED:16365455] [PUBMED:10072079] [PUBMED:12361955] [PUBMED:12755691] [PUBMED:8642247] [PUBMED:15125833] [PUBMED:7509360] [PUBMED:11353765] [PUBMED:12941616] [PUBMED:8700169] [PUBMED:11120819] [PUBMED:15899849] [PUBMED:8990121] [PUBMED:8702662] [PUBMED:8164687] [PUBMED:2141684] [PUBMED:11567141] [PUBMED:9846481] [PUBMED:9489702] [PUBMED:10811803] [PUBMED:11368773] [PUBMED:14557276] [PUBMED:2548204] [PUBMED:10318843] [PUBMED:15536066] [PUBMED:10652356] [PUBMED:7568038] [PUBMED:11175263] [PUBMED:9438848] [PUBMED:9692882] [PUBMED:10209031] [PUBMED:7509083] [PUBMED:12874226] [PUBMED:8673706] [PUBMED:16733527] [PUBMED:9822663] [PUBMED:12738795] [PUBMED:11904433] [PUBMED:8084588] [PUBMED:8114715] [PUBMED:9312162] [PUBMED:8790380] [PUBMED:9677202] [PUBMED:15802604] [PUBMED:14702343] [PUBMED:10903746] [PUBMED:10807788] [PUBMED:8176201] [PUBMED:9207119] [PUBMED:10790433] [PUBMED:8892604] [PUBMED:9665884] [PUBMED:1639064] [PUBMED:12421919] [PUBMED:8246987] [PUBMED:9710204] [PUBMED:8146197] [PUBMED:2190221] [PUBMED:10229072] [PUBMED:10021361] [PUBMED:9924026] [PUBMED:12186560] [PUBMED:16649996] [PUBMED:11287959] [PUBMED:12917261] [PUBMED:7545666] [PUBMED:11250890] [PUBMED:12842872] [PUBMED:15879121] [PUBMED:11567140] [PUBMED:10209041] [PUBMED:10556826] [PUBMED:8183372] [PUBMED:12397360] [PUBMED:10506192] [PUBMED:10861059] [PUBMED:12507424] [PUBMED:12845325] [PUBMED:10745081] [PUBMED:8195151] [PUBMED:12024036] [PUBMED:7524075] [PUBMED:1464315] [PUBMED:12138205] [PUBMED:7544353] [PUBMED:16906149] [PUBMED:9637919] [PUBMED:2470098] [PUBMED:3919143] [PUBMED:16005298] [PUBMED:10918068] [PUBMED:8636141] [PUBMED:16921383] [PUBMED:8479536] [PUBMED:7556092] [PUBMED:16582901] [PUBMED:8805223] [PUBMED:15933714] [PUBMED:10224278] [PUBMED:9819387] [PUBMED:12881521] [PUBMED:14988727] [PUBMED:16849481] [PUBMED:11390650]
TCR signaling in naive CD8+ T cells [NCBI:138055] [Pathway Interaction Database:cd8tcrpathway] [PUBMED:9094314] [PUBMED:15125833] [PUBMED:11994416] [PUBMED:7509360] [PUBMED:12755691] [PUBMED:8642247] [PUBMED:12361955] [PUBMED:11956228] [PUBMED:10072079] [PUBMED:8977171] [PUBMED:2141684] [PUBMED:8700169] [PUBMED:8164687] [PUBMED:9489702] [PUBMED:8702662] [PUBMED:2548204] [PUBMED:11175263] [PUBMED:8114715] [PUBMED:10209031] [PUBMED:15536066] [PUBMED:7678351] [PUBMED:8673703] [PUBMED:7830771] [PUBMED:7509083] [PUBMED:16733527] [PUBMED:9438848] [PUBMED:8790380] [PUBMED:1639064] [PUBMED:15980863] [PUBMED:8084588] [PUBMED:14702343] [PUBMED:10790433] [PUBMED:10807788] [PUBMED:16169499] [PUBMED:15802604] [PUBMED:8892604] [PUBMED:2114552] [PUBMED:12421919] [PUBMED:12917261] [PUBMED:8146197] [PUBMED:1335364] [PUBMED:10021361] [PUBMED:8183372] [PUBMED:8627172] [PUBMED:8898939] [PUBMED:2190221] [PUBMED:9710204] [PUBMED:11287959] [PUBMED:14764585] [PUBMED:12954628] [PUBMED:10209041] [PUBMED:1464315] [PUBMED:12507424] [PUBMED:12732656] [PUBMED:8195151] [PUBMED:12138205] [PUBMED:16005298] [PUBMED:9312149] [PUBMED:7544353] [PUBMED:16906149] [PUBMED:9637919] [PUBMED:12845325] [PUBMED:2470098] [PUBMED:10918068] [PUBMED:16116204] [PUBMED:16921383] [PUBMED:10562325] [PUBMED:9819387] [PUBMED:16582901] [PUBMED:8034711] [PUBMED:8479536] [PUBMED:10640739] [PUBMED:3919143] [PUBMED:10224278] [PUBMED:10811865]
Th1 and Th2 cell differentiation [NCBI:1458885] [KEGG:hsa04658] [PUBMED:15819694] [PUBMED:12171942] [PUBMED:19165228] [PUBMED:23336087] [PUBMED:26044597] [PUBMED:19151746] [PUBMED:19362457] [PUBMED:22044277] [PUBMED:11752608] [PUBMED:23405903] [PUBMED:19375293] [PUBMED:24113868] [PUBMED:19151747] [PUBMED:23624818] [PUBMED:22566933] [PUBMED:11121747] [PUBMED:20969597] [PUBMED:20065998]
Th17 cell differentiation [NCBI:1469482] [KEGG:hsa04659] [PUBMED:23325835] [PUBMED:23036716] [PUBMED:20488727] [PUBMED:21151104] [PUBMED:21084214] [PUBMED:20054607] [PUBMED:22754770] [PUBMED:22640807] [PUBMED:19379825] [PUBMED:22133865] [PUBMED:22324470] [PUBMED:17768419] [PUBMED:18408735] [PUBMED:21776333] [PUBMED:26253381] [PUBMED:16200068] [PUBMED:18362914] [PUBMED:24325586] [PUBMED:19381306] [PUBMED:18166487]
The phototransduction cascade [NCBI:1269627] [REACTOME:R-HSA-2514856] [PUBMED:20430952] [PUBMED:22658984] [PUBMED:20192770]
Thromboxane A2 receptor signaling [NCBI:138060] [Pathway Interaction Database:txa2pathway] [PUBMED:15100160] [PUBMED:11160627] [PUBMED:16859489] [PUBMED:7476920] [PUBMED:12193606] [PUBMED:8474027] [PUBMED:16595906] [PUBMED:11748077] [PUBMED:8948507] [PUBMED:11055976] [PUBMED:15884057] [PUBMED:1825698] [PUBMED:9054415] [PUBMED:1851174] [PUBMED:9862451] [PUBMED:11901221] [PUBMED:14976202] [PUBMED:9915793] [PUBMED:12796499] [PUBMED:16212421] [PUBMED:16956790] [PUBMED:8034687] [PUBMED:17466390] [PUBMED:12183468] [PUBMED:10085139] [PUBMED:9649216] [PUBMED:11873244] [PUBMED:12038794] [PUBMED:10771086] [PUBMED:11015313] [PUBMED:9417126] [PUBMED:12626493] [PUBMED:10827090] [PUBMED:7969066] [PUBMED:8119906] [PUBMED:11389977] [PUBMED:16876780] [PUBMED:16126723] [PUBMED:8636072] [PUBMED:8894620] [PUBMED:11526402] [PUBMED:17229546] [PUBMED:10037795] [PUBMED:15845539] [PUBMED:10670835] [PUBMED:14530262] [PUBMED:8290554] [PUBMED:11443056] [PUBMED:10800962] [PUBMED:9560198] [PUBMED:11389883] [PUBMED:7961988] [PUBMED:10212262] [PUBMED:8245033] [PUBMED:8613548] [PUBMED:7591017] [PUBMED:12187125] [PUBMED:11516166] [PUBMED:10318854]
Vascular smooth muscle contraction [NCBI:96530] [KEGG:hsa04270] [PUBMED:16870827] [PUBMED:10911373] [PUBMED:11679404] [PUBMED:16339747] [PUBMED:10221985] [PUBMED:12689814] [PUBMED:11165670] [PUBMED:18552454] [PUBMED:12060106] [PUBMED:9458738] [PUBMED:15725705] [PUBMED:18040024] [PUBMED:12693609] [PUBMED:11773611] [PUBMED:17158339] [PUBMED:17458653] [PUBMED:15026027] [PUBMED:19120701] [PUBMED:15269340] [PUBMED:18703404] [PUBMED:11709400] [PUBMED:17200683]
Visual phototransduction [NCBI:1269623] [REACTOME:R-HSA-2187338] [PUBMED:15384919] [PUBMED:22074928] [PUBMED:20188572] [PUBMED:21111842] [PUBMED:16688755] [PUBMED:8382952] [PUBMED:22658984] [PUBMED:20430952] [PUBMED:21350678] [PUBMED:22074927] [PUBMED:16011460] [PUBMED:11340090]