full name
calcium voltage-gated channel auxiliary subunit beta 2

synonyms
CACNLB2, CAVB2, MYSB, CACNB2, ENSG00000165995

HGNC
HGNC:1402

Entrez Gene
Gene:783

ENSEMBL
ENSG00000165995

location
chr: 10
start: 18429373
stop: 18830688
strand: +

OMIM
OMIM:600003: CACNB2 (Autosomal dominant inheritance)
OMIM:611876: Brugada syndrome 4

transcripts
NM_201596.2
NM_201593.2
NM_201597.2
NM_201571.3
NM_001167945.1
NM_201572.3
NM_000724.3
NM_201590.2
NM_201570.2

pathways
Adrenaline,noradrenaline inhibits insulin secretion [NCBI:1270103] [REACTOME:R-HSA-400042] [PUBMED:12684222] [PUBMED:7641683] [PUBMED:8997178] [PUBMED:18162464] [PUBMED:10449730] [PUBMED:17900700] [PUBMED:14514350]
Adrenergic signaling in cardiomyocytes [NCBI:908257] [KEGG:hsa04261] [PUBMED:15232578] [PUBMED:20923637] [PUBMED:10571541] [PUBMED:11604549] [PUBMED:17988210] [PUBMED:11805843] [PUBMED:15142747] [PUBMED:21212391] [PUBMED:20658186] [PUBMED:16765984] [PUBMED:19874988] [PUBMED:19883653] [PUBMED:15979723] [PUBMED:18407781] [PUBMED:22022314] [PUBMED:12439640] [PUBMED:17826821] [PUBMED:15765137]
Arrhythmogenic right ventricular cardiomyopathy (ARVC) [NCBI:117293] [KEGG:hsa05412] [PUBMED:16823481] [PUBMED:19205777] [PUBMED:11716909] [PUBMED:12270949] [PUBMED:18382419] [PUBMED:16101641] [PUBMED:16124859] [PUBMED:17413274]
Axon guidance [NCBI:83065] [KEGG:hsa04360] [NCBI:1270303] [REACTOME:R-HSA-422475] [PUBMED:14682358] [PUBMED:15084255] [PUBMED:11687826] [PUBMED:15818466] [PUBMED:15363605] [PUBMED:12471249] [PUBMED:15630019] [PUBMED:11891122] [PUBMED:15960985] [PUBMED:12677003]
Cardiac conduction [NCBI:1339115] [REACTOME:R-HSA-5576891] [PUBMED:19808464] [PUBMED:26140724] [PUBMED:21357845]
Cardiac muscle contraction [NCBI:93344] [KEGG:hsa04260] [PUBMED:16799263] [PUBMED:18981594] [PUBMED:12763850] [PUBMED:16096350] [PUBMED:16552170] [PUBMED:15736582] [PUBMED:14659803] [PUBMED:17988210] [PUBMED:11805843] [PUBMED:10747208] [PUBMED:16701909] [PUBMED:11294886]
Depolarization of the Presynaptic Terminal Triggers the Opening of Calcium Channels [NCBI:1268767] [REACTOME:R-HSA-112308]
Developmental Biology [NCBI:1270302] [REACTOME:R-HSA-1266738]
Dilated cardiomyopathy [NCBI:121494] [KEGG:hsa05414] [PUBMED:11524405] [PUBMED:11805847] [PUBMED:12270949] [PUBMED:14522402] [PUBMED:19017683] [PUBMED:15146239] [PUBMED:18672201] [PUBMED:19273156] [PUBMED:19246813] [PUBMED:11716909] [PUBMED:16817756]
Hypertrophic cardiomyopathy (HCM) [NCBI:114229] [KEGG:hsa05410] [PUBMED:11805847] [PUBMED:18572189] [PUBMED:14711353] [PUBMED:19136482] [PUBMED:18056765] [PUBMED:11225594] [PUBMED:12844200] [PUBMED:10615904] [PUBMED:11716909] [PUBMED:11371514] [PUBMED:12270949]
Integration of energy metabolism [NCBI:1270101] [REACTOME:R-HSA-163685] [PUBMED:15509864] [PUBMED:12721358] [PUBMED:12626323]
MAPK signaling pathway [NCBI:83048] [KEGG:hsa04010] [PUBMED:11749383] [PUBMED:12566928] [PUBMED:12849693] [PUBMED:12676795] [PUBMED:12947395] [PUBMED:14597384] [PUBMED:11369511] [PUBMED:12191611] [PUBMED:12390245]
Metabolism [NCBI:1269956] [REACTOME:R-HSA-1430728]
Muscle contraction [NCBI:1269868] [REACTOME:R-HSA-397014]
NCAM signaling for neurite out-growth [NCBI:1270312] [REACTOME:R-HSA-375165] [PUBMED:18760361] [PUBMED:12587671] [PUBMED:15662836] [PUBMED:17975827] [PUBMED:15153429] [PUBMED:12700044]
NCAM1 interactions [NCBI:1270313] [REACTOME:R-HSA-419037] [PUBMED:18607724] [PUBMED:15662836]
Neuronal System [NCBI:1268763] [REACTOME:R-HSA-112316]
Oxytocin signaling pathway [NCBI:952859] [KEGG:hsa04921] [PUBMED:23356278] [PUBMED:9219843] [PUBMED:20626426] [PUBMED:18555543] [PUBMED:22190926] [PUBMED:21981277] [PUBMED:9575824] [PUBMED:22227279] [PUBMED:19840865] [PUBMED:11861513] [PUBMED:9326674] [PUBMED:12433531] [PUBMED:18655881] [PUBMED:23335873] [PUBMED:22902539] [PUBMED:16156781] [PUBMED:20141572] [PUBMED:14715914] [PUBMED:12009385] [PUBMED:16787565] [PUBMED:16966388]
Phase 0 - rapid depolarisation [NCBI:1339117] [REACTOME:R-HSA-5576892] [PUBMED:21357845] [PUBMED:19808464]
Phase 2 - plateau phase [NCBI:1339119] [REACTOME:R-HSA-5576893] [PUBMED:21357845] [PUBMED:19808464]
Regulation of insulin secretion [NCBI:1270102] [REACTOME:R-HSA-422356] [PUBMED:18200017] [PUBMED:11078440] [PUBMED:16321791] [PUBMED:11815463] [PUBMED:16556766]
Transmission across Chemical Synapses [NCBI:1268766] [REACTOME:R-HSA-112315]