full name
protein kinase, cGMP-dependent, type I

synonyms
1, cGK, PRKG1, ENSG00000185532

HGNC
HGNC:9414

Entrez Gene
Gene:5592

ENSEMBL
ENSG00000185532

location
chr: 10
start: 52750911
stop: 54058110
strand: +

OMIM
OMIM:176894: PRKG1 (Autosomal dominant inheritance)
OMIM:615436: Aortic aneurysm, familial thoracic 8

transcripts
NM_001098512.2
NM_006258.3

pathways
Adaptive Immune System [NCBI:1269171] [REACTOME:R-HSA-1280218] [PUBMED:16551257] [PUBMED:21682741] [PUBMED:11861602]
Beta-catenin independent WNT signaling [NCBI:1269610] [REACTOME:R-HSA-3858494] [PUBMED:22935904] [PUBMED:21903638] [PUBMED:23256519] [PUBMED:8065359] [PUBMED:7739543] [PUBMED:23140633]
Ca2+ pathway [NCBI:1269615] [REACTOME:R-HSA-4086398] [PUBMED:21903638] [PUBMED:21181886] [PUBMED:16099039]
Circadian entrainment [NCBI:698773] [KEGG:hsa04713] [PUBMED:15016477] [PUBMED:12700026] [PUBMED:20605968] [PUBMED:15813931] [PUBMED:15930378] [PUBMED:12573527] [PUBMED:17586087] [PUBMED:20664079] [PUBMED:17646042] [PUBMED:17167088] [PUBMED:16217123] [PUBMED:11294753] [PUBMED:19109992] [PUBMED:10446325] [PUBMED:10208575] [PUBMED:11086993] [PUBMED:19449447]
Gap junction [NCBI:83072] [KEGG:hsa04540] [PUBMED:9535909] [PUBMED:15033578] [PUBMED:12566218] [PUBMED:14506308] [PUBMED:10751659] [PUBMED:10873290] [PUBMED:15955302] [PUBMED:15033579] [PUBMED:15033580] [PUBMED:15094344]
Hemostasis [NCBI:1269340] [REACTOME:R-HSA-109582]
Immune System [NCBI:1269170] [REACTOME:R-HSA-168256]
Long-term depression [NCBI:83086] [KEGG:hsa04730] [PUBMED:9602501] [PUBMED:9735948] [PUBMED:14509570] [PUBMED:11427694] [PUBMED:12415297]
Nitric oxide stimulates guanylate cyclase [NCBI:1269343] [REACTOME:R-HSA-392154] [PUBMED:12881475]
Olfactory transduction [NCBI:83087] [KEGG:hsa04740] [PUBMED:19652915] [PUBMED:22735517] [PUBMED:11557990] [PUBMED:19306880] [PUBMED:16269360] [PUBMED:19941039] [PUBMED:20145624] [PUBMED:12488531] [PUBMED:22875451] [PUBMED:24733839] [PUBMED:10944513]
Platelet activation [NCBI:952858] [KEGG:hsa04611] [PUBMED:20002545] [PUBMED:18363565] [PUBMED:18544684] [PUBMED:18174460] [PUBMED:23106920] [PUBMED:18550847] [PUBMED:22119499] [PUBMED:19630797] [PUBMED:19286885] [PUBMED:17158345] [PUBMED:20089227] [PUBMED:22701130] [PUBMED:21071698] [PUBMED:23805129] [PUBMED:16149014] [PUBMED:18641368]
Platelet homeostasis [NCBI:1269341] [REACTOME:R-HSA-418346] [PUBMED:10798271]
Rap1 signalling [NCBI:1269202] [REACTOME:R-HSA-392517] [PUBMED:16076873]
Regulation of lipolysis in adipocytes [NCBI:1222950] [KEGG:hsa04923] [PUBMED:24676492] [PUBMED:21241784] [PUBMED:17313320] [PUBMED:21900692] [PUBMED:20025992] [PUBMED:19375517] [PUBMED:22298655] [PUBMED:19464318] [PUBMED:24872083] [PUBMED:19136990] [PUBMED:19796963] [PUBMED:18762440] [PUBMED:17878492] [PUBMED:24731595] [PUBMED:17218471]
Salivary secretion [NCBI:153376] [KEGG:hsa04970] [PUBMED:8105741] [PUBMED:10682899] [PUBMED:10928320] [PUBMED:15709965] [PUBMED:17347411] [PUBMED:9720759] [PUBMED:16712780] [PUBMED:16799262] [PUBMED:17157080] [PUBMED:18626068] [PUBMED:15153696] [PUBMED:11936453] [PUBMED:20224180]
Signal Transduction [NCBI:1269379] [REACTOME:R-HSA-162582] [PUBMED:17604717] [PUBMED:19648010] [PUBMED:16260143] [PUBMED:11742412] [PUBMED:19536106] [PUBMED:15863030] [PUBMED:19379690] [PUBMED:19458711] [PUBMED:19935667] [PUBMED:21252999] [PUBMED:15520807] [PUBMED:17496910] [PUBMED:15450248] [PUBMED:18043707] [PUBMED:16939974] [PUBMED:19762341] [PUBMED:18483217] [PUBMED:17084981] [PUBMED:21781017] [PUBMED:19619488]
Signaling by Wnt [NCBI:1269594] [REACTOME:R-HSA-195721] [PUBMED:19530173] [PUBMED:23256519] [PUBMED:22952392] [PUBMED:19204114] [PUBMED:19365405] [PUBMED:19619488] [PUBMED:17143292] [PUBMED:17230199] [PUBMED:18710302] [PUBMED:16099039] [PUBMED:20576942] [PUBMED:10858654] [PUBMED:12967557]
Vascular smooth muscle contraction [NCBI:96530] [KEGG:hsa04270] [PUBMED:16870827] [PUBMED:10911373] [PUBMED:11679404] [PUBMED:16339747] [PUBMED:10221985] [PUBMED:12689814] [PUBMED:11165670] [PUBMED:18552454] [PUBMED:12060106] [PUBMED:9458738] [PUBMED:15725705] [PUBMED:18040024] [PUBMED:12693609] [PUBMED:11773611] [PUBMED:17158339] [PUBMED:17458653] [PUBMED:15026027] [PUBMED:19120701] [PUBMED:15269340] [PUBMED:18703404] [PUBMED:11709400] [PUBMED:17200683]
cGMP effects [NCBI:1269344] [REACTOME:R-HSA-418457] [PUBMED:7913615] [PUBMED:14597579]
cGMP-PKG signaling pathway [NCBI:983748] [KEGG:hsa04022] [PUBMED:18006449] [PUBMED:9003029] [PUBMED:18040025] [PUBMED:19306895] [PUBMED:21666108] [PUBMED:12524221] [PUBMED:16460276] [PUBMED:20716671] [PUBMED:22785374] [PUBMED:11522789] [PUBMED:16439998] [PUBMED:16371594] [PUBMED:20388537] [PUBMED:18757523] [PUBMED:16815627] [PUBMED:23212367] [PUBMED:21685243] [PUBMED:20024580] [PUBMED:15894227] [PUBMED:22965426] [PUBMED:17643091] [PUBMED:19176601] [PUBMED:19961855]