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Genes
ANAPC16
Gene - ANAPC16
full name
anaphase promoting complex subunit 16
synonyms
APC16, bA570G20.3, C10orf104, CENP-27, MSAG, ANAPC16, ENSG00000166295
HGNC
HGNC:26976
Entrez Gene
Gene:119504
ENSEMBL
ENSG00000166295
location
chr: 10
start: 73975758
stop: 73995618
strand: +
transcripts
NM_001242546.1
NM_173473.3
NR_038392.1
NM_001242547.1
NM_001242548.1
NR_038391.1
pathways
APC-Cdc20 mediated degradation of Nek2A
[NCBI:1269847]
[REACTOME:R-HSA-179409]
[PUBMED:11742988]
[PUBMED:16648845]
APC/C-mediated degradation of cell cycle proteins
[NCBI:1269838]
[REACTOME:R-HSA-174143]
[PUBMED:15678131]
[PUBMED:12049731]
APC/C:Cdc20 mediated degradation of Cyclin B
[NCBI:1269848]
[REACTOME:R-HSA-174048]
[PUBMED:11285280]
APC/C:Cdc20 mediated degradation of Securin
[NCBI:1269849]
[REACTOME:R-HSA-174154]
[PUBMED:12070128]
[PUBMED:10827941]
APC/C:Cdc20 mediated degradation of mitotic proteins
[NCBI:1269844]
[REACTOME:R-HSA-176409]
[PUBMED:15949434]
[PUBMED:10465783]
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
[NCBI:1269851]
[REACTOME:R-HSA-174178]
[PUBMED:16413484]
[PUBMED:15678131]
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint
[NCBI:1269845]
[REACTOME:R-HSA-179419]
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins
[NCBI:1269842]
[REACTOME:R-HSA-176814]
[PUBMED:15678131]
Autodegradation of Cdh1 by Cdh1:APC/C
[NCBI:1269852]
[REACTOME:R-HSA-174084]
[PUBMED:15029244]
Cdc20:Phospho-APC/C mediated degradation of Cyclin A
[NCBI:1269846]
[REACTOME:R-HSA-174184]
[PUBMED:11285280]
Cell Cycle
[NCBI:1269741]
[REACTOME:R-HSA-1640170]
Cell Cycle Checkpoints
[NCBI:1269742]
[REACTOME:R-HSA-69620]
Cell Cycle, Mitotic
[NCBI:1269763]
[REACTOME:R-HSA-69278]
Cellular Senescence
[NCBI:1270426]
[REACTOME:R-HSA-2559583]
[PUBMED:21078816]
[PUBMED:18711403]
[PUBMED:22048312]
[PUBMED:19818705]
[PUBMED:17662938]
[PUBMED:23746838]
[PUBMED:9282108]
[PUBMED:17667954]
[PUBMED:13905658]
Cellular responses to stress
[NCBI:1270414]
[REACTOME:R-HSA-2262752]
[PUBMED:15709958]
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
[NCBI:1269850]
[REACTOME:R-HSA-176407]
[PUBMED:15678131]
Inactivation of APC/C via direct inhibition of the APC/C complex
[NCBI:1269762]
[REACTOME:R-HSA-141430]
[PUBMED:14593737]
[PUBMED:11535616]
[PUBMED:9637688]
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
[NCBI:1269761]
[REACTOME:R-HSA-141405]
[PUBMED:14593737]
M Phase
[NCBI:1269810]
[REACTOME:R-HSA-68886]
Mitotic Anaphase
[NCBI:1269825]
[REACTOME:R-HSA-68882]
Mitotic Metaphase and Anaphase
[NCBI:1269823]
[REACTOME:R-HSA-2555396]
Mitotic Spindle Checkpoint
[NCBI:1269758]
[REACTOME:R-HSA-69618]
[PUBMED:14593737]
[PUBMED:12360190]
Phosphorylation of the APC/C
[NCBI:1269843]
[REACTOME:R-HSA-176412]
[PUBMED:10793135]
Regulation of APC/C activators between G1/S and early anaphase
[NCBI:1269839]
[REACTOME:R-HSA-176408]
[PUBMED:16508672]
[PUBMED:12049731]
[PUBMED:12208841]
[PUBMED:15678131]
Regulation of mitotic cell cycle
[NCBI:1269837]
[REACTOME:R-HSA-453276]
Senescence-Associated Secretory Phenotype (SASP)
[NCBI:1270431]
[REACTOME:R-HSA-2559582]
[PUBMED:18411265]
[PUBMED:21979375]
[PUBMED:18267069]
[PUBMED:19597488]
[PUBMED:19218920]
[PUBMED:20818427]
[PUBMED:11114305]
[PUBMED:8617720]
[PUBMED:22178396]
[PUBMED:19805069]
[PUBMED:23770676]
[PUBMED:8384717]
[PUBMED:18555777]
[PUBMED:21686281]
[PUBMED:20351173]
[PUBMED:8688489]
[PUBMED:19053174]
[PUBMED:8234276]
[PUBMED:18555778]
Separation of Sister Chromatids
[NCBI:1269826]
[REACTOME:R-HSA-2467813]
[PUBMED:11081627]
[PUBMED:10411507]
[PUBMED:12070128]
[PUBMED:12194817]
[PUBMED:11509732]