full name
surfactant protein A2

synonyms
COLEC5, PSAP, PSP-A, PSPA, SFTP1, SFTPA2B, SP-A, SPA2, SPAII, SFTPA2, ENSG00000185303

HGNC
HGNC:10799

Entrez Gene
Gene:729238

ENSEMBL
ENSG00000185303

location
chr: 10
start: 81315608
stop: 81320177
strand: -

OMIM
OMIM:178642: SFTPA2 (Autosomal dominant inheritance)
OMIM:178500: Pulmonary fibrosis, idiopathic

transcripts
NM_001098668.2

pathways
ABC transporter disorders [NCBI:1268933] [REACTOME:R-HSA-5619084] [PUBMED:21740521] [PUBMED:16399363] [PUBMED:23415156] [PUBMED:21389634] [PUBMED:21488864] [PUBMED:21554546]
Defective ABCA3 causes pulmonary surfactant metabolism dysfunction type 3 (SMDP3) [NCBI:1339131] [REACTOME:R-HSA-5683678] [PUBMED:15044640] [PUBMED:23415156] [PUBMED:21967062] [PUBMED:25621661]
Defective CSF2RA causes pulmonary surfactant metabolism dysfunction 4 (SMDP4) [NCBI:1309214] [REACTOME:R-HSA-5688890] [PUBMED:25621661]
Defective CSF2RB causes pulmonary surfactant metabolism dysfunction 5 (SMDP5) [NCBI:1309215] [REACTOME:R-HSA-5688849] [PUBMED:25621661] [PUBMED:19666756]
Defective SFTPA2 causes idiopathic pulmonary fibrosis (IPF) [NCBI:1309210] [REACTOME:R-HSA-5687868] [PUBMED:18366757] [PUBMED:22850886]
Disease [NCBI:1268854] [REACTOME:R-HSA-1643685]
Diseases associated with surfactant metabolism [NCBI:1309208] [REACTOME:R-HSA-5687613] [PUBMED:25621661]
Diseases of metabolism [NCBI:1268939] [REACTOME:R-HSA-5668914]
Disorders of transmembrane transporters [NCBI:1268932] [REACTOME:R-HSA-5619115] [PUBMED:16399363]
FOXA1 transcription factor network [NCBI:137979] [Pathway Interaction Database:hnf3apathway] [PUBMED:9427758] [PUBMED:16087863] [PUBMED:12750453] [PUBMED:12441652] [PUBMED:11763995] [PUBMED:8441395] [PUBMED:8164696] [PUBMED:2786140] [PUBMED:8071346] [PUBMED:8598458] [PUBMED:16331276] [PUBMED:16214823] [PUBMED:10049364] [PUBMED:15987773] [PUBMED:10073575] [PUBMED:8058060] [PUBMED:16980581] [PUBMED:9685261] [PUBMED:16009131]
Metabolism of proteins [NCBI:1268677] [REACTOME:R-HSA-392499]
Pertussis [NCBI:218111] [KEGG:hsa05133] [PUBMED:20610650] [PUBMED:12701623] [PUBMED:15201703] [PUBMED:18401006] [PUBMED:20210554] [PUBMED:16622221] [PUBMED:17148436] [PUBMED:21204863] [PUBMED:20404851] [PUBMED:10540218] [PUBMED:16999837] [PUBMED:16481212] [PUBMED:16863919] [PUBMED:16390441] [PUBMED:21423776] [PUBMED:17328678] [PUBMED:12915094]
Phagosome [NCBI:153910] [KEGG:hsa04145] [PUBMED:17637737] [PUBMED:18513324] [PUBMED:15894272] [PUBMED:10684585] [PUBMED:18492791] [PUBMED:15036145] [PUBMED:17245426]
Surfactant metabolism [NCBI:1309223] [REACTOME:R-HSA-5683826] [PUBMED:20551227] [PUBMED:23026158] [PUBMED:24868212] [PUBMED:23736009] [PUBMED:16423266] [PUBMED:23441475] [PUBMED:19824815] [PUBMED:8162991] [PUBMED:16580255] [PUBMED:19037882]