Logo
full name
actin, alpha 2, smooth muscle, aorta

synonyms
AAT6, ACTSA, MYMY5, ACTA2, ENSG00000107796

HGNC
HGNC:130

Entrez Gene
Gene:59

ENSEMBL
ENSG00000107796

location
chr: 10
start: 90694831
stop: 90751147
strand: -

OMIM
OMIM:102620: ACTA2 (Autosomal dominant inheritance)
OMIM:611788: Aortic aneurysm, familial thoracic 6
OMIM:614042: Moyamoya disease 5
OMIM:613834: Multisystemic smooth muscle dysfunction syndrome

transcripts
NM_001141945.1
NM_001613.2

pathways
Apelin signaling pathway [NCBI:1492886] [KEGG:hsa04371] [PUBMED:23973488] [PUBMED:16182514] [PUBMED:21725702] [PUBMED:22842084] [PUBMED:27825851] [PUBMED:27650065] [PUBMED:22140623] [PUBMED:23943882] [PUBMED:26944568] [PUBMED:24055369] [PUBMED:26385179] [PUBMED:26143239] [PUBMED:22028387] [PUBMED:26254105] [PUBMED:26756969] [PUBMED:22995518] [PUBMED:27979574] [PUBMED:23924696] [PUBMED:21464822] [PUBMED:25914650] [PUBMED:24990699] [PUBMED:26607438] [PUBMED:25164121] [PUBMED:25275559] [PUBMED:25139773] [PUBMED:25931124] [PUBMED:19093215] [PUBMED:20539939] [PUBMED:25652330] [PUBMED:18272138] [PUBMED:23603510]
Muscle contraction [NCBI:1269868] [REACTOME:R-HSA-397014]
Smooth Muscle Contraction [NCBI:1269870] [REACTOME:R-HSA-445355] [PUBMED:14627618]
Vascular smooth muscle contraction [NCBI:96530] [KEGG:hsa04270] [PUBMED:16870827] [PUBMED:10911373] [PUBMED:11679404] [PUBMED:16339747] [PUBMED:10221985] [PUBMED:12689814] [PUBMED:11165670] [PUBMED:18552454] [PUBMED:12060106] [PUBMED:9458738] [PUBMED:15725705] [PUBMED:18040024] [PUBMED:12693609] [PUBMED:11773611] [PUBMED:17158339] [PUBMED:17458653] [PUBMED:15026027] [PUBMED:19120701] [PUBMED:15269340] [PUBMED:18703404] [PUBMED:11709400] [PUBMED:17200683]