full name
fibroblast growth factor receptor 2
synonyms
BBDS, BEK, BFR-1, CD332, CEK3, CFD1, ECT1, JWS, K-SAM, KGFR, TK14, TK25, FGFR2, ENSG00000066468
HGNC
HGNC:3689
Entrez Gene
Gene:2263
ENSEMBL
ENSG00000066468
location
chr: 10
start: 123237844
stop: 123357972
strand: -
OMIM
OMIM:176943:
FGFR2
(Autosomal recessive inheritance)
OMIM:207410:
Antley-Bixler syndrome without genital anomalies or disordered steroidogenesis
OMIM:101200:
Apert syndrome
OMIM:123790:
Beare-Stevenson cutis gyrata syndrome
OMIM:614592:
Bent bone dysplasia syndrome
OMIM:101600:
Craniofacial-skeletal-dermatologic dysplasia
OMIM:123500:
Crouzon syndrome
OMIM:613659:
Gastric cancer, somatic
OMIM:123150:
Jackson-Weiss syndrome
OMIM:149730:
LADD syndrome
OMIM:101600:
Pfeiffer syndrome
OMIM:101400:
Saethre-Chotzen syndrome
OMIM:609579:
Scaphocephaly, maxillary retrusion, and mental retardation
transcripts
NM_001144918.1
NR_073009.1
NM_001144917.1
NM_000141.4
NM_022970.3
NM_001144915.1
NM_001144916.1
NM_023029.2
NM_001144914.1
NM_001144919.1
NM_001144913.1
pathways
ARMS-mediated activation
[NCBI:1269471]
[REACTOME:R-HSA-170984]
[PUBMED:9069267]
Activated point mutants of FGFR2
[NCBI:1268871]
[REACTOME:R-HSA-2033519]
[PUBMED:17525745]
[PUBMED:8841188]
[PUBMED:9539778]
[PUBMED:7719344]
[PUBMED:9154000]
[PUBMED:7874169]
[PUBMED:11325814]
[PUBMED:11121055]
[PUBMED:20106510]
[PUBMED:7773297]
[PUBMED:15282208]
[PUBMED:18552176]
[PUBMED:17803937]
[PUBMED:17552943]
[PUBMED:18757403]
[PUBMED:8696350]
[PUBMED:9538690]
Adaptive Immune System
[NCBI:1269171]
[REACTOME:R-HSA-1280218]
[PUBMED:16551257]
[PUBMED:21682741]
[PUBMED:11861602]
Axon guidance
[NCBI:83065]
[KEGG:hsa04360]
[NCBI:1270303]
[REACTOME:R-HSA-422475]
[PUBMED:14682358]
[PUBMED:15084255]
[PUBMED:11687826]
[PUBMED:15818466]
[PUBMED:15363605]
[PUBMED:12471249]
[PUBMED:15630019]
[PUBMED:11891122]
[PUBMED:15960985]
[PUBMED:12677003]
Central carbon metabolism in cancer
[NCBI:1059538]
[KEGG:hsa05230]
[PUBMED:16982728]
[PUBMED:21127244]
[PUBMED:22349059]
[PUBMED:19270154]
[PUBMED:24113830]
[PUBMED:22156302]
[PUBMED:21801601]
[PUBMED:15916903]
[PUBMED:18177721]
[PUBMED:22237205]
[PUBMED:20520704]
[PUBMED:23018234]
[PUBMED:23897900]
[PUBMED:24398961]
[PUBMED:24079832]
[PUBMED:18538731]
[PUBMED:19460998]
[PUBMED:22307140]
[PUBMED:18766298]
[PUBMED:22101401]
[PUBMED:23071355]
[PUBMED:21508971]
[PUBMED:24738035]
[PUBMED:22750268]
[PUBMED:21258394]
[PUBMED:23279446]
[PUBMED:21340684]
Constitutive Signaling by Aberrant PI3K in Cancer
[NCBI:1268880]
[REACTOME:R-HSA-2219530]
[PUBMED:18317450]
[PUBMED:19962665]
[PUBMED:20009532]
[PUBMED:20713702]
[PUBMED:21478295]
[PUBMED:16339315]
[PUBMED:18079394]
[PUBMED:17626883]
Cytokine Signaling in Immune system
[NCBI:1269310]
[REACTOME:R-HSA-1280215]
[PUBMED:12613569]
DAP12 interactions
[NCBI:1269283]
[REACTOME:R-HSA-2172127]
[PUBMED:19120482]
[PUBMED:17220916]
[PUBMED:9490415]
[PUBMED:18192027]
[PUBMED:15884055]
DAP12 signaling
[NCBI:1269284]
[REACTOME:R-HSA-2424491]
[PUBMED:15884055]
[PUBMED:17110943]
[PUBMED:17220916]
Developmental Biology
[NCBI:1270302]
[REACTOME:R-HSA-1266738]
Disease
[NCBI:1268854]
[REACTOME:R-HSA-1643685]
Diseases of signal transduction
[NCBI:1268855]
[REACTOME:R-HSA-5663202]
[PUBMED:12509752]
Downstream signal transduction
[NCBI:1269479]
[REACTOME:R-HSA-186763]
[PUBMED:10508235]
[PUBMED:9739761]
Downstream signaling events of B Cell Receptor (BCR)
[NCBI:1269185]
[REACTOME:R-HSA-1168372]
[PUBMED:17052215]
[PUBMED:19909372]
Downstream signaling of activated FGFR2
[NCBI:1269403]
[REACTOME:R-HSA-5654696]
[PUBMED:8752212]
EGFR tyrosine kinase inhibitor resistance
[NCBI:1404798]
[KEGG:hsa01521]
[PUBMED:16843264]
[PUBMED:23401451]
[PUBMED:20966921]
[PUBMED:24307395]
[PUBMED:22956644]
[PUBMED:25232485]
[PUBMED:24493829]
[PUBMED:23071030]
[PUBMED:18483355]
[PUBMED:24202392]
[PUBMED:19632948]
[PUBMED:23361103]
[PUBMED:26579470]
[PUBMED:22970367]
[PUBMED:23358468]
[PUBMED:17554333]
[PUBMED:25337673]
[PUBMED:22474259]
[PUBMED:20551942]
Endocytosis
[NCBI:102279]
[KEGG:hsa04144]
[PUBMED:19696797]
[PUBMED:19007773]
[PUBMED:16203612]
[PUBMED:15687999]
[PUBMED:19924646]
[PUBMED:15261671]
[PUBMED:18647649]
[PUBMED:19325624]
[PUBMED:20110990]
[PUBMED:22193161]
FCERI mediated MAPK activation
[NCBI:1269299]
[REACTOME:R-HSA-2871796]
[PUBMED:19290926]
[PUBMED:19909365]
[PUBMED:17122878]
FGF signaling pathway
[NCBI:137989]
[Pathway Interaction Database:fgf_pathway]
[PUBMED:12419216]
[PUBMED:16775459]
[PUBMED:1656221]
[PUBMED:16857743]
[PUBMED:8707855]
[PUBMED:17545628]
[PUBMED:17623664]
[PUBMED:16893902]
[PUBMED:15105428]
[PUBMED:16436388]
[PUBMED:12370824]
[PUBMED:9707175]
[PUBMED:1380001]
[PUBMED:15569927]
[PUBMED:11241670]
[PUBMED:11433297]
[PUBMED:16709412]
[PUBMED:12815057]
[PUBMED:14966081]
[PUBMED:17086194]
[PUBMED:17311277]
[PUBMED:14534538]
[PUBMED:12398894]
[PUBMED:8940113]
[PUBMED:17266935]
[PUBMED:10652257]
[PUBMED:12604616]
[PUBMED:14666721]
[PUBMED:9045692]
[PUBMED:15509650]
[PUBMED:11353842]
[PUBMED:12791257]
[PUBMED:15564375]
[PUBMED:12529371]
[PUBMED:17409417]
[PUBMED:17005551]
[PUBMED:12815619]
[PUBMED:11997436]
[PUBMED:12110689]
[PUBMED:17627937]
FGFR2 ligand binding and activation
[NCBI:1269400]
[REACTOME:R-HSA-190241]
[PUBMED:16844695]
[PUBMED:16597617]
[PUBMED:17133345]
FGFR2 mutant receptor activation
[NCBI:1268870]
[REACTOME:R-HSA-1839126]
[PUBMED:15282208]
[PUBMED:17552943]
[PUBMED:9266968]
[PUBMED:17803937]
[PUBMED:9816310]
[PUBMED:18757403]
[PUBMED:11003564]
[PUBMED:20101236]
[PUBMED:18337450]
[PUBMED:9538690]
[PUBMED:17525745]
[PUBMED:10626794]
[PUBMED:11056689]
[PUBMED:18381441]
[PUBMED:11325814]
[PUBMED:9539778]
[PUBMED:19103595]
[PUBMED:9154000]
[PUBMED:20106510]
[PUBMED:17505008]
[PUBMED:18552176]
FGFR2b ligand binding and activation
[NCBI:1269401]
[REACTOME:R-HSA-190377]
[PUBMED:16597617]
FGFR2c ligand binding and activation
[NCBI:1269402]
[REACTOME:R-HSA-190375]
[PUBMED:16597617]
FRS-mediated FGFR2 signaling
[NCBI:1269404]
[REACTOME:R-HSA-5654700]
[PUBMED:18452557]
[PUBMED:11447289]
[PUBMED:16682955]
[PUBMED:15863030]
Fc epsilon receptor (FCERI) signaling
[NCBI:1269298]
[REACTOME:R-HSA-2454202]
[PUBMED:15099567]
[PUBMED:21799019]
Frs2-mediated activation
[NCBI:1269470]
[REACTOME:R-HSA-170968]
[PUBMED:9069267]
GAB1 signalosome
[NCBI:1269384]
[REACTOME:R-HSA-180292]
[PUBMED:15550174]
GRB2 events in EGFR signaling
[NCBI:1269382]
[REACTOME:R-HSA-179812]
[PUBMED:11706405]
[PUBMED:11498013]
Gastrin-CREB signalling pathway via PKC and MAPK
[NCBI:1269592]
[REACTOME:R-HSA-881907]
[PUBMED:10413847]
[PUBMED:7491953]
[PUBMED:17698287]
IGF1R signaling cascade
[NCBI:1269618]
[REACTOME:R-HSA-2428924]
[PUBMED:17598937]
[PUBMED:20975071]
[PUBMED:22649417]
[PUBMED:21042815]
[PUBMED:18927274]
[PUBMED:20098959]
IRS-mediated signalling
[NCBI:1269431]
[REACTOME:R-HSA-112399]
IRS-related events triggered by IGF1R
[NCBI:1269620]
[REACTOME:R-HSA-2428928]
[PUBMED:17598937]
[PUBMED:20975071]
[PUBMED:22649417]
[PUBMED:18927274]
[PUBMED:21042815]
[PUBMED:20098959]
Immune System
[NCBI:1269170]
[REACTOME:R-HSA-168256]
Innate Immune System
[NCBI:1269203]
[REACTOME:R-HSA-168249]
Insulin receptor signalling cascade
[NCBI:1269429]
[REACTOME:R-HSA-74751]
[PUBMED:9677303]
[PUBMED:11282018]
Interleukin receptor SHC signaling
[NCBI:1269322]
[REACTOME:R-HSA-912526]
[PUBMED:8294403]
Interleukin-2 signaling
[NCBI:1269321]
[REACTOME:R-HSA-451927]
[PUBMED:17936914]
[PUBMED:18817510]
[PUBMED:19543225]
[PUBMED:18062768]
Interleukin-3, 5 and GM-CSF signaling
[NCBI:1269323]
[REACTOME:R-HSA-512988]
[PUBMED:10450743]
[PUBMED:9766809]
MAPK family signaling cascades
[NCBI:1269501]
[REACTOME:R-HSA-5683057]
[PUBMED:21167873]
[PUBMED:17161475]
[PUBMED:22535895]
[PUBMED:21372320]
MAPK signaling pathway
[NCBI:83048]
[KEGG:hsa04010]
[PUBMED:11749383]
[PUBMED:12566928]
[PUBMED:12849693]
[PUBMED:12676795]
[PUBMED:12947395]
[PUBMED:14597384]
[PUBMED:11369511]
[PUBMED:12191611]
[PUBMED:12390245]
MAPK1/MAPK3 signaling
[NCBI:1269502]
[REACTOME:R-HSA-5684996]
[PUBMED:25378393]
[PUBMED:18199641]
[PUBMED:17496909]
[PUBMED:21779496]
[PUBMED:15520807]
[PUBMED:16393692]
[PUBMED:19520853]
[PUBMED:17496910]
[PUBMED:22569528]
NCAM signaling for neurite out-growth
[NCBI:1270312]
[REACTOME:R-HSA-375165]
[PUBMED:18760361]
[PUBMED:12587671]
[PUBMED:15662836]
[PUBMED:17975827]
[PUBMED:15153429]
[PUBMED:12700044]
NGF signalling via TRKA from the plasma membrane
[NCBI:1269460]
[REACTOME:R-HSA-187037]
[PUBMED:11520933]
[PUBMED:12676795]
[PUBMED:10851172]
[PUBMED:10579918]
Negative regulation of FGFR2 signaling
[NCBI:1269408]
[REACTOME:R-HSA-5654727]
[PUBMED:12815057]
[PUBMED:18452557]
[PUBMED:11997436]
[PUBMED:20940169]
Negative regulation of the PI3K/AKT network
[NCBI:1269191]
[REACTOME:R-HSA-199418]
PI-3K cascade:FGFR2
[NCBI:1269407]
[REACTOME:R-HSA-5654695]
[PUBMED:10918587]
[PUBMED:15863030]
[PUBMED:11057895]
[PUBMED:12558974]
[PUBMED:12089343]
PI3K Cascade
[NCBI:1269432]
[REACTOME:R-HSA-109704]
PI3K-Akt signaling pathway
[NCBI:692234]
[KEGG:hsa04151]
[PUBMED:12048182]
[PUBMED:11357143]
[PUBMED:21440011]
[PUBMED:15209374]
[PUBMED:12669022]
[PUBMED:18842113]
[PUBMED:16847462]
[PUBMED:12660731]
[PUBMED:17360849]
[PUBMED:9838078]
[PUBMED:15505410]
[PUBMED:16248975]
[PUBMED:12531180]
[PUBMED:21779440]
[PUBMED:16187290]
[PUBMED:15784165]
[PUBMED:21620960]
PI3K/AKT Signaling in Cancer
[NCBI:1268879]
[REACTOME:R-HSA-2219528]
[PUBMED:20713702]
[PUBMED:10555148]
[PUBMED:19644473]
[PUBMED:17611497]
[PUBMED:21478295]
[PUBMED:17626883]
[PUBMED:16339315]
[PUBMED:18317450]
[PUBMED:18079394]
[PUBMED:9467011]
[PUBMED:17604717]
[PUBMED:9326929]
[PUBMED:18954143]
[PUBMED:20009532]
[PUBMED:19962665]
[PUBMED:21430697]
[PUBMED:19487573]
[PUBMED:10866302]
PI3K/AKT activation
[NCBI:1269473]
[REACTOME:R-HSA-198203]
[PUBMED:10579926]
[PUBMED:12123609]
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
[NCBI:1383020]
[REACTOME:R-HSA-6811558]
[PUBMED:12422219]
[PUBMED:16979564]
[PUBMED:19805105]
[PUBMED:17200115]
[PUBMED:21827948]
[PUBMED:19576174]
[PUBMED:18753295]
[PUBMED:19896968]
[PUBMED:16456541]
[PUBMED:25495341]
[PUBMED:15464023]
[PUBMED:23758345]
[PUBMED:9367159]
[PUBMED:9211928]
[PUBMED:17245604]
PIP3 activates AKT signaling
[NCBI:1269188]
[REACTOME:R-HSA-1257604]
Pathways in cancer
[NCBI:83105]
[KEGG:hsa05200]
[PUBMED:12244301]
[PUBMED:15156182]
[PUBMED:16899407]
[PUBMED:12621137]
[PUBMED:21193867]
[PUBMED:16001072]
[PUBMED:11707511]
[PUBMED:11253051]
[PUBMED:11071626]
[PUBMED:17251915]
[PUBMED:11736900]
[PUBMED:16557281]
[PUBMED:16699851]
[PUBMED:16189702]
[PUBMED:11902573]
[PUBMED:16555243]
[PUBMED:8069858]
[PUBMED:15310786]
[PUBMED:9834202]
[PUBMED:16700615]
[PUBMED:12545153]
[PUBMED:15656799]
[PUBMED:12154354]
[PUBMED:11895903]
[PUBMED:11527574]
[PUBMED:16326109]
[PUBMED:16339096]
[PUBMED:11160144]
[PUBMED:15724144]
[PUBMED:12951584]
[PUBMED:10647931]
[PUBMED:16881963]
[PUBMED:15557758]
[PUBMED:11477132]
[PUBMED:15721476]
[PUBMED:15625120]
[PUBMED:16236521]
[PUBMED:14967450]
[PUBMED:15942304]
[PUBMED:17287871]
[PUBMED:14634372]
[PUBMED:15573119]
[PUBMED:15009714]
[PUBMED:16112428]
[PUBMED:15611513]
[PUBMED:16001050]
[PUBMED:15349822]
[PUBMED:16551846]
[PUBMED:15978322]
[PUBMED:15774796]
[PUBMED:16352814]
[PUBMED:12951588]
[PUBMED:10944551]
[PUBMED:10740269]
[PUBMED:15639402]
[PUBMED:12407699]
[PUBMED:11130178]
[PUBMED:15109562]
[PUBMED:11170304]
[PUBMED:11276000]
[PUBMED:9643506]
[PUBMED:16248975]
[PUBMED:16242838]
[PUBMED:12946833]
[PUBMED:11559746]
[PUBMED:9196022]
[PUBMED:12079267]
[PUBMED:15468170]
[PUBMED:16064138]
[PUBMED:14580692]
[PUBMED:15082523]
[PUBMED:15551095]
[PUBMED:17062879]
[PUBMED:17211469]
[PUBMED:11720739]
[PUBMED:12588368]
[PUBMED:11057895]
[PUBMED:9422516]
[PUBMED:12894244]
[PUBMED:15479695]
[PUBMED:16189154]
[PUBMED:12878745]
[PUBMED:11900250]
[PUBMED:11103787]
[PUBMED:15122209]
[PUBMED:12711111]
[PUBMED:12243753]
[PUBMED:16306523]
[PUBMED:16702400]
[PUBMED:15270885]
[PUBMED:14685170]
[PUBMED:14586404]
[PUBMED:11078609]
[PUBMED:15284264]
[PUBMED:10505543]
[PUBMED:11223406]
[PUBMED:14982876]
[PUBMED:12648469]
[PUBMED:12867060]
[PUBMED:15711891]
[PUBMED:12094241]
[PUBMED:16642045]
[PUBMED:11463388]
[PUBMED:12762887]
[PUBMED:15746962]
[PUBMED:15823750]
[PUBMED:16750612]
[PUBMED:16484590]
[PUBMED:11459867]
[PUBMED:16146838]
[PUBMED:14556242]
[PUBMED:15947972]
[PUBMED:12563308]
[PUBMED:16946003]
[PUBMED:15948971]
[PUBMED:11407945]
[PUBMED:12737309]
[PUBMED:16095998]
[PUBMED:12351585]
[PUBMED:24508914]
[PUBMED:12084351]
[PUBMED:11807782]
[PUBMED:14695152]
[PUBMED:10453277]
[PUBMED:17554387]
[PUBMED:15841168]
[PUBMED:12616528]
[PUBMED:10403855]
[PUBMED:16054233]
[PUBMED:16474624]
[PUBMED:16822996]
[PUBMED:17028294]
[PUBMED:11224709]
[PUBMED:11750244]
[PUBMED:11905738]
[PUBMED:15719031]
[PUBMED:10843728]
[PUBMED:16110317]
[PUBMED:11721960]
[PUBMED:12741677]
[PUBMED:7585656]
[PUBMED:12801837]
[PUBMED:16551847]
[PUBMED:12459728]
[PUBMED:11431710]
[PUBMED:12468433]
[PUBMED:11165748]
[PUBMED:16042571]
[PUBMED:16508724]
[PUBMED:15000146]
[PUBMED:17149381]
[PUBMED:15948711]
[PUBMED:14747944]
[PUBMED:14737121]
[PUBMED:12379883]
[PUBMED:17158541]
[PUBMED:12850530]
[PUBMED:10835690]
[PUBMED:16870043]
Phospholipase C-mediated cascade; FGFR2
[NCBI:1269405]
[REACTOME:R-HSA-5654221]
[PUBMED:10579907]
[PUBMED:1656221]
[PUBMED:15863030]
Prolonged ERK activation events
[NCBI:1269469]
[REACTOME:R-HSA-169893]
[PUBMED:12765839]
[PUBMED:9069267]
Prostate cancer
[NCBI:83111]
[KEGG:hsa05215]
[PUBMED:12878745]
[PUBMED:11900250]
[PUBMED:11527574]
[PUBMED:11750244]
[PUBMED:16551847]
[PUBMED:10835690]
[PUBMED:8069858]
[PUBMED:15724144]
[PUBMED:10453277]
[PUBMED:15082523]
[PUBMED:9422516]
RAF/MAP kinase cascade
[NCBI:1269285]
[REACTOME:R-HSA-5673001]
[PUBMED:21167873]
[PUBMED:24937142]
[PUBMED:20674547]
[PUBMED:17496910]
[PUBMED:22177953]
[PUBMED:17496919]
[PUBMED:22569528]
[PUBMED:22535895]
[PUBMED:12068308]
[PUBMED:17496923]
[PUBMED:19091303]
[PUBMED:21372320]
[PUBMED:21388974]
[PUBMED:15520807]
RET signaling
[NCBI:1427866]
[REACTOME:R-HSA-8853659]
[PUBMED:15013219]
[PUBMED:17036197]
Rap1 signaling pathway
[NCBI:868086]
[KEGG:hsa04015]
[PUBMED:17624944]
[PUBMED:12351703]
[PUBMED:10579920]
[PUBMED:19159611]
[PUBMED:18363565]
[PUBMED:12765839]
[PUBMED:12508104]
[PUBMED:11331911]
[PUBMED:17182900]
[PUBMED:15803158]
[PUBMED:19615876]
[PUBMED:21402149]
[PUBMED:17624948]
[PUBMED:17383543]
[PUBMED:14607972]
[PUBMED:15780587]
[PUBMED:19710505]
Ras signaling pathway
[NCBI:868085]
[KEGG:hsa04014]
[PUBMED:23506953]
[PUBMED:18437264]
[PUBMED:15062121]
[PUBMED:22189424]
[PUBMED:22233291]
[PUBMED:12778136]
[PUBMED:11313946]
[PUBMED:17428555]
[PUBMED:19091743]
[PUBMED:18568040]
[PUBMED:20420946]
[PUBMED:12217381]
[PUBMED:14663478]
[PUBMED:21686117]
[PUBMED:12642680]
[PUBMED:21196257]
[PUBMED:16869784]
[PUBMED:21111786]
[PUBMED:16966426]
[PUBMED:10712923]
[PUBMED:22020205]
[PUBMED:17384584]
[PUBMED:15572660]
[PUBMED:18413813]
Regulation of actin cytoskeleton
[NCBI:83089]
[KEGG:hsa04810]
[PUBMED:11152757]
[PUBMED:11082272]
[PUBMED:10574699]
[PUBMED:11082269]
[PUBMED:14657486]
[PUBMED:14744429]
[PUBMED:12700767]
Role of LAT2/NTAL/LAB on calcium mobilization
[NCBI:1269302]
[REACTOME:R-HSA-2730905]
[PUBMED:17993265]
[PUBMED:20643813]
[PUBMED:17420272]
SHC-mediated cascade:FGFR2
[NCBI:1269406]
[REACTOME:R-HSA-5654699]
[PUBMED:8264585]
[PUBMED:9480847]
[PUBMED:9045692]
[PUBMED:18840094]
[PUBMED:15863030]
SHC1 events in EGFR signaling
[NCBI:1269383]
[REACTOME:R-HSA-180336]
[PUBMED:11498013]
[PUBMED:8755247]
SOS-mediated signalling
[NCBI:1269440]
[REACTOME:R-HSA-112412]
Signal Transduction
[NCBI:1269379]
[REACTOME:R-HSA-162582]
[PUBMED:17604717]
[PUBMED:19648010]
[PUBMED:16260143]
[PUBMED:11742412]
[PUBMED:19536106]
[PUBMED:15863030]
[PUBMED:19379690]
[PUBMED:19458711]
[PUBMED:19935667]
[PUBMED:21252999]
[PUBMED:15520807]
[PUBMED:17496910]
[PUBMED:15450248]
[PUBMED:18043707]
[PUBMED:16939974]
[PUBMED:19762341]
[PUBMED:18483217]
[PUBMED:17084981]
[PUBMED:21781017]
[PUBMED:19619488]
Signaling by EGFR
[NCBI:1269380]
[REACTOME:R-HSA-177929]
[PUBMED:10459005]
[PUBMED:10404636]
[PUBMED:12297041]
[PUBMED:15142631]
Signaling by FGFR
[NCBI:1269386]
[REACTOME:R-HSA-190236]
[PUBMED:15863038]
[PUBMED:12080084]
[PUBMED:20602996]
[PUBMED:15863030]
[PUBMED:15567848]
[PUBMED:7917292]
[PUBMED:19247306]
[PUBMED:16597617]
Signaling by FGFR in disease
[NCBI:1268863]
[REACTOME:R-HSA-1226099]
[PUBMED:17552943]
[PUBMED:10053006]
[PUBMED:8640234]
[PUBMED:9865713]
[PUBMED:21367659]
[PUBMED:10471491]
[PUBMED:21711248]
[PUBMED:9538690]
[PUBMED:20094046]
[PUBMED:9539778]
[PUBMED:12461689]
[PUBMED:9438390]
[PUBMED:8841188]
[PUBMED:11055896]
[PUBMED:8599935]
[PUBMED:21160078]
[PUBMED:9207791]
[PUBMED:9154000]
[PUBMED:18381441]
[PUBMED:20179196]
[PUBMED:8755573]
[PUBMED:20226962]
[PUBMED:8798788]
[PUBMED:19066716]
[PUBMED:17505008]
[PUBMED:11429702]
Signaling by FGFR2
[NCBI:1269399]
[REACTOME:R-HSA-5654738]
[PUBMED:19247306]
[PUBMED:16597617]
[PUBMED:15863038]
[PUBMED:12080084]
[PUBMED:15863030]
[PUBMED:20602996]
[PUBMED:15567848]
[PUBMED:7917292]
Signaling by FGFR2 IIIa TM
[NCBI:1383045]
[REACTOME:R-HSA-8851708]
[PUBMED:21355848]
Signaling by FGFR2 amplification mutants
[NCBI:1268872]
[REACTOME:R-HSA-2023837]
[PUBMED:17505008]
[PUBMED:9266968]
[PUBMED:9816310]
[PUBMED:11003564]
[PUBMED:20101236]
[PUBMED:18337450]
[PUBMED:10626794]
[PUBMED:18381441]
[PUBMED:11056689]
[PUBMED:19103595]
Signaling by FGFR2 fusions
[NCBI:1383046]
[REACTOME:R-HSA-8853333]
[PUBMED:23558953]
[PUBMED:22975805]
[PUBMED:24588013]
[PUBMED:24122810]
Signaling by FGFR2 in disease
[NCBI:1268869]
[REACTOME:R-HSA-5655253]
[PUBMED:9154000]
[PUBMED:17505008]
[PUBMED:17552943]
[PUBMED:21367659]
[PUBMED:21711248]
[PUBMED:9538690]
[PUBMED:18381441]
[PUBMED:19147536]
Signaling by GPCR
[NCBI:1269543]
[REACTOME:R-HSA-372790]
[PUBMED:16902930]
[PUBMED:10202136]
[PUBMED:18043707]
Signaling by Insulin receptor
[NCBI:1269428]
[REACTOME:R-HSA-74752]
[PUBMED:8276779]
Signaling by Interleukins
[NCBI:1269318]
[REACTOME:R-HSA-449147]
[PUBMED:19302047]
[PUBMED:12445398]
Signaling by Leptin
[NCBI:1269632]
[REACTOME:R-HSA-2586552]
[PUBMED:22211890]
[PUBMED:23562747]
[PUBMED:20600241]
[PUBMED:21622208]
[PUBMED:23579596]
[PUBMED:22458591]
[PUBMED:21489811]
[PUBMED:19724019]
[PUBMED:21331644]
[PUBMED:22448029]
[PUBMED:21147620]
[PUBMED:20198122]
[PUBMED:21677426]
[PUBMED:20029269]
[PUBMED:22249808]
[PUBMED:22991412]
[PUBMED:21527729]
[PUBMED:17937601]
[PUBMED:20553370]
[PUBMED:21713385]
[PUBMED:23565489]
[PUBMED:22289780]
Signaling by PDGF
[NCBI:1269478]
[REACTOME:R-HSA-186797]
[PUBMED:15207811]
[PUBMED:10508235]
[PUBMED:9739761]
Signaling by SCF-KIT
[NCBI:1269487]
[REACTOME:R-HSA-1433557]
[PUBMED:17350321]
[PUBMED:16483568]
[PUBMED:7688988]
[PUBMED:19540337]
[PUBMED:16475976]
[PUBMED:15526160]
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
[NCBI:1269617]
[REACTOME:R-HSA-2404192]
[PUBMED:21042815]
[PUBMED:18927274]
[PUBMED:20098959]
[PUBMED:17598937]
[PUBMED:20975071]
[PUBMED:22044904]
[PUBMED:22649417]
Signaling by VEGF
[NCBI:1269480]
[REACTOME:R-HSA-194138]
[PUBMED:15585754]
[PUBMED:13678960]
[PUBMED:16336962]
[PUBMED:16835467]
Signaling by the B Cell Receptor (BCR)
[NCBI:1269183]
[REACTOME:R-HSA-983705]
[PUBMED:1702903]
[PUBMED:2011584]
[PUBMED:1081164]
[PUBMED:19065780]
[PUBMED:16849466]
[PUBMED:1375264]
[PUBMED:7538118]
[PUBMED:11901194]
[PUBMED:8580068]
[PUBMED:19249086]
[PUBMED:18596693]
[PUBMED:10648173]
[PUBMED:4589993]
[PUBMED:8163536]
[PUBMED:1376928]
[PUBMED:7688784]
[PUBMED:6335036]
[PUBMED:17052215]
[PUBMED:18818202]
[PUBMED:20206686]
[PUBMED:7592958]
[PUBMED:7524079]
[PUBMED:15489917]
[PUBMED:15509800]
[PUBMED:18187424]
[PUBMED:7927516]
[PUBMED:803528]
[PUBMED:19909372]
[PUBMED:20192804]
[PUBMED:8306975]
Signaling pathways regulating pluripotency of stem cells
[NCBI:1026136]
[KEGG:hsa04550]
[PUBMED:20705693]
[PUBMED:23653415]
[PUBMED:16518401]
[PUBMED:17211451]
[PUBMED:22649650]
[PUBMED:24910449]
[PUBMED:19551525]
[PUBMED:22298652]
[PUBMED:23370346]
[PUBMED:24315442]
[PUBMED:18414030]
[PUBMED:17647265]
[PUBMED:18295576]
[PUBMED:24957798]
[PUBMED:24147644]
[PUBMED:16153702]
[PUBMED:19427042]
[PUBMED:18220859]
[PUBMED:19571885]
[PUBMED:23585347]
Signalling by NGF
[NCBI:1269443]
[REACTOME:R-HSA-166520]
Signalling to ERKs
[NCBI:1269464]
[REACTOME:R-HSA-187687]
[PUBMED:10508738]
Signalling to RAS
[NCBI:1269465]
[REACTOME:R-HSA-167044]
[PUBMED:11520933]
Signalling to p38 via RIT and RIN
[NCBI:1269468]
[REACTOME:R-HSA-187706]
[PUBMED:10712923]
VEGFA-VEGFR2 Pathway
[NCBI:1269483]
[REACTOME:R-HSA-4420097]
[PUBMED:17344076]
[PUBMED:16633338]
[PUBMED:19230644]
[PUBMED:13678960]
VEGFR2 mediated cell proliferation
[NCBI:1269485]
[REACTOME:R-HSA-5218921]
[PUBMED:22866201]
[PUBMED:22180219]
[PUBMED:22762016]
